Publications by authors named "Carl Anderson"

100Publications

Multicomponent granular mixing in a Bohle bin Blender-Experiments and simulation.

Int J Pharm 2020 Mar 11;578:119131. Epub 2020 Feb 11.

Department of Pharmaceutical Sciences, University of Connecticut, USA; Department of Chemical and Biomolecular Engineering, University of Connecticut, USA; Institute of Material Sciences, University of Connecticut, USA.

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http://dx.doi.org/10.1016/j.ijpharm.2020.119131DOI Listing
March 2020

Terahertz Time of Flight Spectroscopy as a Coating Thickness Reference Method for Partial Least Squares Near Infrared Spectroscopy Models.

Anal Chem 2020 03 20;92(5):3658-3665. Epub 2020 Feb 20.

Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, United States.

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http://dx.doi.org/10.1021/acs.analchem.9b04750DOI Listing
March 2020

Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles.

Sci Immunol 2019 11;4(41)

Laboratory of Applied Evolutionary Biology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1126/sciimmunol.aay6125DOI Listing
November 2019

HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease.

Gastroenterology 2020 01 7;158(1):189-199. Epub 2019 Oct 7.

Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.09.041DOI Listing
January 2020

Determining the effect of photodegradation on film coated nifedipine tablets with terahertz based coating thickness measurements.

Eur J Pharm Biopharm 2019 Dec 27;145:35-41. Epub 2019 Sep 27.

Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA 15282, United States; Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, PA 15282, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2019.09.024DOI Listing
December 2019

Refractive Index Measurement of Pharmaceutical Solids: A Review of Measurement Methods and Pharmaceutical Applications.

J Pharm Sci 2019 11 17;108(11):3478-3495. Epub 2019 Jul 17.

Division of Pharmaceutical, Social and Administrative Sciences, Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282; Division of Pharmaceutical, Social and Administrative Sciences, Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, Pennsylvania 15282. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2019.06.029DOI Listing
November 2019

Urinary apolipoprotein AI in children with kidney disease.

Pediatr Nephrol 2019 11 23;34(11):2351-2360. Epub 2019 Jun 23.

Division of Pediatric Nephrology, Monroe Carrell Children's Hospital at Vanderbilt, Nashville, TN, USA.

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http://dx.doi.org/10.1007/s00467-019-04289-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801060PMC
November 2019

Development of an In-Line Near-Infrared Method for Blend Content Uniformity Assessment in a Tablet Feed Frame.

Appl Spectrosc 2019 Sep 5;73(9):1028-1040. Epub 2019 Jun 5.

GlaxoSmithKline, Analytical Sciences and Development, Collegeville, PA, USA.

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http://journals.sagepub.com/doi/10.1177/0003702819842189
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http://dx.doi.org/10.1177/0003702819842189DOI Listing
September 2019

Feedforward and Feedback Control of a Pharmaceutical Coating Process.

AAPS PharmSciTech 2019 Apr 1;20(4):157. Epub 2019 Apr 1.

Duquesne University Graduate School of Pharmaceutical Sciences, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1208/s12249-019-1348-5DOI Listing
April 2019

Prediction of Dissolution Profiles From Process Parameters, Formulation, and Spectroscopic Measurements.

J Pharm Sci 2019 06 8;108(6):2119-2127. Epub 2019 Feb 8.

Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2019.01.023DOI Listing
June 2019

Susceptibility or Resilience to Maltreatment Can Be Explained by Specific Differences in Brain Network Architecture.

Biol Psychiatry 2019 04 2;85(8):690-702. Epub 2018 Nov 2.

Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.biopsych.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440838PMC
April 2019

Influence of moisture variation on the performance of Raman spectroscopy in quantitative pharmaceutical analyses.

J Pharm Biomed Anal 2019 Feb 15;164:528-535. Epub 2018 Oct 15.

Duquesne University Graduate School of Pharmaceutical Sciences, Pittsburgh, PA 15282, United States; Duquesne University Center for Pharmaceutical Technology, Pittsburgh, PA 15282, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.10.022DOI Listing
February 2019

Revealing a human p53 universe.

Nucleic Acids Res 2018 09;46(16):8153-8167

Genome Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences/National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/nar/gky720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144829PMC
September 2018

N-acetylcysteine blocks serotonin 1B agonist-induced OCD-related behavior in mice.

Behav Neurosci 2018 Aug 9;132(4):258-268. Epub 2018 Jul 9.

Department of Psychology.

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http://dx.doi.org/10.1037/bne0000251DOI Listing
August 2018

Method Development and Validation of an Inline Process Analytical Technology Method for Blend Monitoring in the Tablet Feed Frame Using Raman Spectroscopy.

Anal Chem 2018 07 3;90(14):8436-8444. Epub 2018 Jul 3.

GlaxoSmithKline , Analytical Sciences and Development , King of Prussia , Pennsylvania 19406 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b01009DOI Listing
July 2018

Consequences of Identifying XIAP Deficiency in an Adult Patient With Inflammatory Bowel Disease.

Gastroenterology 2018 07 9;155(1):231-234. Epub 2018 Jun 9.

Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK; Translational Gastroenterology Unit, Experimental Medicine Division, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1053/j.gastro.2018.03.069DOI Listing
July 2018

Does sleep disruption mediate the effects of childhood maltreatment on brain structure?

Eur J Psychotraumatol 2017 28;8(Suppl 7):1450594. Epub 2018 Mar 28.

Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1080/20008198.2018.1450594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965034PMC
March 2018

Differential effects of childhood neglect and abuse during sensitive exposure periods on male and female hippocampus.

Neuroimage 2018 04 27;169:443-452. Epub 2017 Dec 27.

Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street, Belmont MA 02478, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, 02115, United States; Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States.

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http://dx.doi.org/10.1016/j.neuroimage.2017.12.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856615PMC
April 2018

A robust quantitative near infrared modeling approach for blend monitoring.

J Pharm Biomed Anal 2018 Jan 9;148:51-57. Epub 2017 Sep 9.

Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, PA 15282, United States; Duquesne University Graduate School for Pharmaceutical Sciences, Pittsburgh, PA 15282, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2017.09.011DOI Listing
January 2018

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Gut 2018 08 4;67(8):1517-1524. Epub 2017 Aug 4.

Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/gutjnl-2016-313598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797498PMC
August 2018

Determination of Spatially Resolved Tablet Density and Hardness Using Near-Infrared Chemical Imaging (NIR-CI).

Appl Spectrosc 2017 Aug 21;71(8):1906-1914. Epub 2017 Mar 21.

1 Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1177/0003702817693856DOI Listing
August 2017

Designing a calibration set in spectral space for efficient development of an NIR method for tablet analysis.

J Pharm Biomed Anal 2017 Oct 17;145:230-239. Epub 2017 Jun 17.

Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA; Duquesne University Center for Pharmaceutical Technology, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2017.06.012DOI Listing
October 2017

In-line monitoring and optimization of powder flow in a simulated continuous process using transmission near infrared spectroscopy.

Int J Pharm 2017 Jun 23;526(1-2):199-208. Epub 2017 Apr 23.

Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA, 15282, USA; Duquesne University Center for Pharmaceutical Technology, 600 Forbes Avenue, Pittsburgh, PA, 15282, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.04.054DOI Listing
June 2017

Investigation of the Sensitivity of Transmission Raman Spectroscopy for Polymorph Detection in Pharmaceutical Tablets.

Appl Spectrosc 2017 Aug 30;71(8):1856-1867. Epub 2017 Mar 30.

2 GlaxoSmithKline, Analytical Science and Development, King of Prussia, PA, USA.

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http://dx.doi.org/10.1177/0003702817690407DOI Listing
August 2017

Childhood maltreatment is associated with alteration in global network fiber-tract architecture independent of history of depression and anxiety.

Neuroimage 2017 04 16;150:50-59. Epub 2017 Feb 16.

Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill St., Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2017.02.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386807PMC
April 2017

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression.

Cell Death Differ 2017 01 11;24(1):181-191. Epub 2016 Nov 11.

Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.

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http://www.nature.com/articles/cdd2016130
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http://dx.doi.org/10.1038/cdd.2016.130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260499PMC
January 2017

Understanding the Impact of Chemical Variability and Calibration Algorithms on Prediction of Solid Fraction of Roller Compacted Ribbons Using Near-Infrared (NIR) Spectroscopy.

Appl Spectrosc 2017 Jun 4;71(6):1209-1221. Epub 2016 Nov 4.

4 Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1177/0003702816671960DOI Listing
June 2017

The effects of childhood maltreatment on brain structure, function and connectivity.

Nat Rev Neurosci 2016 09;17(10):652-66

Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/nrn.2016.111DOI Listing
September 2016

A reference panel of 64,976 haplotypes for genotype imputation.

Authors:
Shane McCarthy Sayantan Das Warren Kretzschmar Olivier Delaneau Andrew R Wood Alexander Teumer Hyun Min Kang Christian Fuchsberger Petr Danecek Kevin Sharp Yang Luo Carlo Sidore Alan Kwong Nicholas Timpson Seppo Koskinen Scott Vrieze Laura J Scott He Zhang Anubha Mahajan Jan Veldink Ulrike Peters Carlos Pato Cornelia M van Duijn Christopher E Gillies Ilaria Gandin Massimo Mezzavilla Arthur Gilly Massimiliano Cocca Michela Traglia Andrea Angius Jeffrey C Barrett Dorrett Boomsma Kari Branham Gerome Breen Chad M Brummett Fabio Busonero Harry Campbell Andrew Chan Sai Chen Emily Chew Francis S Collins Laura J Corbin George Davey Smith George Dedoussis Marcus Dorr Aliki-Eleni Farmaki Luigi Ferrucci Lukas Forer Ross M Fraser Stacey Gabriel Shawn Levy Leif Groop Tabitha Harrison Andrew Hattersley Oddgeir L Holmen Kristian Hveem Matthias Kretzler James C Lee Matt McGue Thomas Meitinger David Melzer Josine L Min Karen L Mohlke John B Vincent Matthias Nauck Deborah Nickerson Aarno Palotie Michele Pato Nicola Pirastu Melvin McInnis J Brent Richards Cinzia Sala Veikko Salomaa David Schlessinger Sebastian Schoenherr P Eline Slagboom Kerrin Small Timothy Spector Dwight Stambolian Marcus Tuke Jaakko Tuomilehto Leonard H Van den Berg Wouter Van Rheenen Uwe Volker Cisca Wijmenga Daniela Toniolo Eleftheria Zeggini Paolo Gasparini Matthew G Sampson James F Wilson Timothy Frayling Paul I W de Bakker Morris A Swertz Steven McCarroll Charles Kooperberg Annelot Dekker David Altshuler Cristen Willer William Iacono Samuli Ripatti Nicole Soranzo Klaudia Walter Anand Swaroop Francesco Cucca Carl A Anderson Richard M Myers Michael Boehnke Mark I McCarthy Richard Durbin

Nat Genet 2016 10 22;48(10):1279-83. Epub 2016 Aug 22.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388176PMC
October 2016

Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.

J Clin Endocrinol Metab 2016 12 15;101(12):4521-4531. Epub 2016 Aug 15.

University of Cambridge Metabolic Research Laboratories (A.K.N., E.S., G.L., V.K.K.C., N.S.), Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom; Department of Human Genetics (E.G.S., C.A.A.), The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; Research Centre for Regenerative and Restorative Medicine (H.C.), Department of Medical Genetics Istanbul Medipol University, Kavacık, Istanbul, Turkey; Pediatric Endocrine Unit (S.A., I.U.), Department of Child Health, Sultan Qaboos University Hospital, Muscat, Oman; Paediatric Endocrinology Department (A.D.), Mafraq Hospital, AbuDhabi, United Arab Emirates; Pediatric Department Prince Mohamed Bin Abdulaziz Hospital (A.M.H.), Madinah, Kingdom of Saudi Arabia; Department of Paediatrics (M.A.), Madina Maternity & Children's Hospital Madina Munawara, Saudi Arabia; 8. Department of Endocrinology (C.P.), Great Ormond St Hospital for Children, London, United Kingdom; Department of Paediatrics (N.N.), Luton and Dunstable University Hospital, Luton, United Kingdom; Division of Paediatric Endocrinology (Z.A.), Dr Sami Ulus Woman Health and Children Research Hospital Ankara, Turkey; Department of Paediatric Endocrinology (H.S.), Uludağ University, School of Medicine Bursa, Turkey; Department of Paediatric Endocrinology (E.B.), Dokuz Eylül University, Faculty of Medicine Izmir, Turkey; Developmental Endocrinology Research Group (M.D.), Section of Genetics and Epigenetics in Health and Disease, Genetics and Genomic Medicine Programme, University College London Institute of Child Health, London, United Kingdom; Department of Paediatrics (S.S.), Leicester Royal infirmary, Leicester United Kingdom; Centre for Paediatrics and Child Health (P.G.M.), Institute of Human Development University of Manchester, and Royal Manchester Children's Hospital, Manchester, United Kingdom; Paediatric Endocrinology Division (A.B.), College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia; Department of Paediatrics (R.W., A.T.), University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom; W Midlands Regional Genetics Laboratory (R.I.), Birmingham Women's Hospital NHS Foundation Trust, Birmingham, United Kingdom; Department of Paediatric Endocrinology (R.P.), Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom; Department of Paediatrics (K.T.), Diana Princess of Wales Hospital, Grimsby, United Kingdom; Department of Paediatric Endocrinology (J.H.D.), University Hospital Southampton, Southampton, United Kingdom; Department of Paediatrics (V.P.), Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough, United Kingdom; Department of Clinical Genetics (S.-M.P.), Cambridge University Hospitals NHS Foundation Trust, Cambridge United Kingdom; London N W Healthcare NHS Trust (A.F.M.), Harrow, Middlesex, United Kingdom; Division of Population Medicine (J.W.G.), School of Medicine, Cardiff University, Heath Park Cardiff, UK; Department of Paediatric Endocrinology (A.A.), St George's University Hospitals NHS Foundation Trust, London, United Kingdom; Centre for Endocrinology (E.P.-G.), William Harvey Research Institute, Queen Mary University London and Children's Hospital, Barts Health NHS Trust, London, United Kingdom; Department of Medical Genetics (H.M., K.B., E.R.M.), University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1210/jc.2016-1879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155683PMC
December 2016

Effect of Sampling Frequency for Real-Time Tablet Coating Monitoring Using Near Infrared Spectroscopy.

Appl Spectrosc 2016 Sep 8;70(9):1476-88. Epub 2016 Aug 8.

Duquesne Center for Pharmaceutical Technology, Duquesne University, USA Graduate School of Pharmaceutical Sciences, Duquesne University, USA

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http://dx.doi.org/10.1177/0003702816662622DOI Listing
September 2016

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Nat Commun 2016 08 9;7:12342. Epub 2016 Aug 9.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1038/ncomms12342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980482PMC
August 2016

Method development and validation for pharmaceutical tablets analysis using transmission Raman spectroscopy.

Int J Pharm 2016 Feb 30;498(1-2):318-25. Epub 2015 Nov 30.

Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, United States; Duquesne Center for Pharmaceutical Technology, Duquesne University, 600 Forbes Avenue, Pittsburgh PA 15282, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2015.11.049DOI Listing
February 2016

Near-Infrared Spatially Resolved Spectroscopy for Tablet Quality Determination.

J Pharm Sci 2015 Dec 28;104(12):4074-4081. Epub 2015 Aug 28.

Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania; Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282. Electronic address:

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http://dx.doi.org/10.1002/jps.24618DOI Listing
December 2015

Improving near-infrared prediction model robustness with support vector machine regression: a pharmaceutical tablet assay example.

Appl Spectrosc 2014 1;68(12):1348-56. Epub 2014 Nov 1.

Duquesne University Center for Pharmaceutical Technology, School of Pharmacy, 600 Forbes Avenue, Pittsburgh, PA 15282 USA.

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http://dx.doi.org/10.1366/14-07486DOI Listing
July 2015

Host genetic variants and gene expression patterns associated with Epstein-Barr virus copy number in lymphoblastoid cell lines.

PLoS One 2014 7;9(10):e108384. Epub 2014 Oct 7.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; Department of Infection, Division of Infection and Immunity, University College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108384PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188571PMC
June 2015

Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy.

Int J Pharm 2014 Oct 6;473(1-2):219-31. Epub 2014 Jul 6.

Duquesne Center for Pharmaceutical Technology, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2014.06.061DOI Listing
October 2014

Genetic studies of Crohn's disease: past, present and future.

Best Pract Res Clin Gastroenterol 2014 Jun 6;28(3):373-86. Epub 2014 May 6.

The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bpg.2014.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075408PMC
June 2014

p53 vs. ISG15: stop, you're killing me.

Cell Cycle 2014 9;13(14):2160-1. Epub 2014 Jun 9.

Chromosome Stability Section; Laboratory of Molecular Genetics; National Institute of Environmental Health Sciences; Research Triangle Park, NC USA; Biosciences Department; Brookhaven National Laboratory; Upton, NY USA.

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http://dx.doi.org/10.4161/cc.29466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111670PMC
December 2015

Genetics in PSC: what do the "risk genes" teach us?

Clin Rev Allergy Immunol 2015 Jun;48(2-3):154-64

Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital Rikshospitalet, 4950 Nydalen, 0424, Oslo, Norway.

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http://dx.doi.org/10.1007/s12016-014-8417-zDOI Listing
June 2015

Sensitive periods of amygdala development: the role of maltreatment in preadolescence.

Neuroimage 2014 Aug 13;97:236-44. Epub 2014 Apr 13.

Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478-9106, USA; Department of Psychiatry, Harvard Medical School, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2014.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258391PMC
August 2014

Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects.

Am J Hum Genet 2014 Feb 23;94(2):295-302. Epub 2014 Jan 23.

Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928658PMC
February 2014

Mutant TP53 posttranslational modifications: challenges and opportunities.

Hum Mutat 2014 Jun 11;35(6):738-55. Epub 2014 Feb 11.

Chromosome Stability Section, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1002/humu.22506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074372PMC
June 2014

Effects and detection of raw material variability on the performance of near-infrared calibration models for pharmaceutical products.

J Pharm Sci 2014 Feb 12;103(2):545-56. Epub 2013 Dec 12.

Duquesne University Center for Pharmaceutical Technology, School of Pharmacy, Pittsburgh, Pennsylvania, 15282.

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http://dx.doi.org/10.1002/jps.23816DOI Listing
February 2014

Childhood maltreatment: altered network centrality of cingulate, precuneus, temporal pole and insula.

Biol Psychiatry 2014 Aug 2;76(4):297-305. Epub 2013 Oct 2.

Developmental Biopsychiatry Research Program, McLean Hospital, Belmont; Department of Psychiatry, Northeastern University, Boston, Massachusetts; Harvard Medical School, and School of Nursing, Northeastern University, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.biopsych.2013.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258110PMC
August 2014

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.

Cell 2013 Sep 12;155(1):57-69. Epub 2013 Sep 12.

Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1016/j.cell.2013.08.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790457PMC
September 2013

Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells.

Nucleic Acids Res 2013 Aug 17;41(15):7286-301. Epub 2013 Jun 17.

Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC 27709, USA, Systems Biology Group, Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC 27709, USA, William G. Enloe High School, Raleigh, NC 27610, USA and Department of Biology, Brookhaven National Laboratory, Upton, NY 11973, USA.

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http://dx.doi.org/10.1093/nar/gkt504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753631PMC
August 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

Compensation, crosstalk and sequestering: the currency of checkpoints in cancer.

Cell Cycle 2013 Apr 2;12(8):1163-4. Epub 2013 Apr 2.

Department of Pathology and Laboratory of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674080PMC
April 2013

Reduced visual cortex gray matter volume and thickness in young adults who witnessed domestic violence during childhood.

PLoS One 2012 26;7(12):e52528. Epub 2012 Dec 26.

Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530484PMC
July 2013

Effect of experimental design on the prediction performance of calibration models based on near-infrared spectroscopy for pharmaceutical applications.

Appl Spectrosc 2012 Dec;66(12):1442-53

Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282, USA.

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December 2012

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Development of a fluid bed granulation design space using critical quality attribute weighted tolerance intervals.

J Pharm Sci 2012 Aug 8;101(8):2917-29. Epub 2012 May 8.

Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania 15282, USA.

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August 2012

Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum.

Proc Natl Acad Sci U S A 2012 Feb 13;109(9):E563-72. Epub 2012 Feb 13.

Developmental Biopsychiatry Research Program and Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295326PMC
February 2012

Distinct p53 genomic binding patterns in normal and cancer-derived human cells.

Cell Cycle 2011 Dec 15;10(24):4237-49. Epub 2011 Dec 15.

Biology Department, Brookhaven National Laboratory, Upton, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272258PMC
December 2011

Radial tensile strength prediction of relaxing and relaxed compacts by near-infrared chemical imaging.

Int J Pharm 2011 Oct 20;418(2):297-303. Epub 2011 May 20.

Duquesne University Center for Pharmaceutical Technology, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.

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October 2011

Food and Drug Administration guidance: supervisory responsibilities of investigators.

J Diabetes Sci Technol 2011 Mar 1;5(2):433-8. Epub 2011 Mar 1.

Carl A. Anderson, LLC, Tacoma, Washington 98407, USA.

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http://dx.doi.org/10.1177/193229681100500234DOI Listing
March 2011

Performance-based quality specifications: the relationship between process critical control parameters, critical quality attributes, and clinical performance.

J Pharm Sci 2011 Apr 30;100(4):1566-75. Epub 2010 Nov 30.

Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282.

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April 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Basic statistical analysis in genetic case-control studies.

Nat Protoc 2011 Feb 3;6(2):121-33. Epub 2011 Feb 3.

Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154648PMC
February 2011

Synthetic associations are unlikely to account for many common disease genome-wide association signals.

PLoS Biol 2011 Jan 18;9(1):e1000580. Epub 2011 Jan 18.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB101HH, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022527PMC
January 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

Data quality control in genetic case-control association studies.

Nat Protoc 2010 Sep 26;5(9):1564-73. Epub 2010 Aug 26.

Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/nprot.2010.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025522PMC
September 2010

Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation.

J Biol Chem 2011 Jan 26;286(1):252-8. Epub 2010 Oct 26.

Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012982PMC
January 2011

Pharmaceutical applications of separation of absorption and scattering in near-infrared spectroscopy (NIRS).

J Pharm Sci 2010 Dec;99(12):4766-83

Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, USA.

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December 2010

Application of Monte Carlo simulation-based photon migration for enhanced understanding of near-infrared (NIR) diffuse reflectance. Part II: Photon radial diffusion in NIR chemical images.

J Pharm Sci 2010 Oct;99(10):4174-82

Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, USA.

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October 2010

Harsh corporal punishment is associated with increased T2 relaxation time in dopamine-rich regions.

Neuroimage 2010 Nov 25;53(2):412-9. Epub 2010 Jun 25.

Developmental Biopsychiatry Research Program, McLean Hospital, Belmont MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854930PMC
November 2010

A new definition of pharmaceutical quality: assembly of a risk simulation platform to investigate the impact of manufacturing/product variability on clinical performance.

J Pharm Sci 2010 Dec;99(12):5046-59

Duquesne University Graduate School of Pharmaceutical Sciences, 410A Mellon Hall, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, USA.

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December 2010

Posttranslational modification of p53: cooperative integrators of function.

Cold Spring Harb Perspect Biol 2009 Dec 28;1(6):a000950. Epub 2009 Oct 28.

Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882125PMC
December 2009

Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

Authors:
Jason Z Liu Federica Tozzi Dawn M Waterworth Sreekumar G Pillai Pierandrea Muglia Lefkos Middleton Wade Berrettini Christopher W Knouff Xin Yuan Gérard Waeber Peter Vollenweider Martin Preisig Nicholas J Wareham Jing Hua Zhao Ruth J F Loos Inês Barroso Kay-Tee Khaw Scott Grundy Philip Barter Robert Mahley Antero Kesaniemi Ruth McPherson John B Vincent John Strauss James L Kennedy Anne Farmer Peter McGuffin Richard Day Keith Matthews Per Bakke Amund Gulsvik Susanne Lucae Marcus Ising Tanja Brueckl Sonja Horstmann H-Erich Wichmann Rajesh Rawal Norbert Dahmen Claudia Lamina Ozren Polasek Lina Zgaga Jennifer Huffman Susan Campbell Jaspal Kooner John C Chambers Mary Susan Burnett Joseph M Devaney Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Stephen Epstein James F Wilson Sarah H Wild Harry Campbell Veronique Vitart Muredach P Reilly Mingyao Li Liming Qu Robert Wilensky William Matthai Hakon H Hakonarson Daniel J Rader Andre Franke Michael Wittig Arne Schäfer Manuela Uda Antonio Terracciano Xiangjun Xiao Fabio Busonero Paul Scheet David Schlessinger David St Clair Dan Rujescu Gonçalo R Abecasis Hans Jörgen Grabe Alexander Teumer Henry Völzke Astrid Petersmann Ulrich John Igor Rudan Caroline Hayward Alan F Wright Ivana Kolcic Benjamin J Wright John R Thompson Anthony J Balmforth Alistair S Hall Nilesh J Samani Carl A Anderson Tariq Ahmad Christopher G Mathew Miles Parkes Jack Satsangi Mark Caulfield Patricia B Munroe Martin Farrall Anna Dominiczak Jane Worthington Wendy Thomson Steve Eyre Anne Barton Vincent Mooser Clyde Francks Jonathan Marchini

Nat Genet 2010 May 25;42(5):436-40. Epub 2010 Apr 25.

Department of Statistics, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612983PMC
May 2010

Application of Monte Carlo simulation-based photon migration for enhanced understanding of near-infrared (NIR) diffuse reflectance. Part I: Depth of penetration in pharmaceutical materials.

J Pharm Sci 2010 May;99(5):2399-412

Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, USA.

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May 2010