Carina Ittrich

Carina Ittrich

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Carina Ittrich

Carina Ittrich

Publications by authors named "Carina Ittrich"

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Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study.

Lancet Respir Med 2019 Sep 17;7(9):771-779. Epub 2019 Jul 17.

National Institute for Health Research Respiratory Biomedical Research Centre, City Campus, Nottingham University Hospital, Nottingham, UK.

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http://dx.doi.org/10.1016/S2213-2600(19)30255-3DOI Listing
September 2019

Influence of field potential duration on spontaneous beating rate of human induced pluripotent stem cell-derived cardiomyocytes: Implications for data analysis and test system selection.

J Pharmacol Toxicol Methods 2016 Nov - Dec;82:74-82. Epub 2016 Aug 9.

Boehringer Ingelheim Pharma GmbH & Co. KG, Drug Discovery Support, Birkendorfer Straße 65, 88397 Biberach, Germany.

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http://dx.doi.org/10.1016/j.vascn.2016.08.002DOI Listing
May 2017

An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes.

J Pharmacol Toxicol Methods 2015 Sep-Oct;75:91-100. Epub 2015 Apr 25.

Drug Discovery Support, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Strasse 65, 88397 Biberach, Germany.

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http://dx.doi.org/10.1016/j.vascn.2015.04.005DOI Listing
July 2016

Influence of TCF7L2 gene variants on the therapeutic response to the dipeptidylpeptidase-4 inhibitor linagliptin.

Diabetologia 2014 Sep 7;57(9):1869-75. Epub 2014 Jun 7.

Drug Metabolism and Pharmacokinetics, Development, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88397, Biberach/Riss, Germany,

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http://link.springer.com/10.1007/s00125-014-3276-y
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http://dx.doi.org/10.1007/s00125-014-3276-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119242PMC
September 2014

The transcriptional programme of contact-inhibition.

J Cell Biochem 2010 Aug;110(5):1234-43

Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr 67, 55131 Mainz, Germany.

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http://dx.doi.org/10.1002/jcb.22638DOI Listing
August 2010

Flibanserin, a drug intended for treatment of hypoactive sexual desire disorder in pre-menopausal women, affects spontaneous motor activity and brain neurochemistry in female rats.

Naunyn Schmiedebergs Arch Pharmacol 2010 Jun 27;381(6):573-9. Epub 2010 Apr 27.

CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Strasse 65, 88397, Biberach, Germany.

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http://dx.doi.org/10.1007/s00210-010-0515-8DOI Listing
June 2010

High-dimensional Cox models: the choice of penalty as part of the model building process.

Biom J 2010 Feb;52(1):50-69

Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/bimj.200900064DOI Listing
February 2010

Comparative transcriptome and proteome analysis of Ha-ras and B-raf mutated mouse liver tumors.

J Proteome Res 2009 Aug;8(8):3987-94

Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, University of Tubingen, Germany.

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http://dx.doi.org/10.1021/pr9002933DOI Listing
August 2009

Gene expression profiles of adult peripheral and cord blood mononuclear cells altered by lipopolysaccharide.

Neonatology 2008 16;93(2):87-100. Epub 2007 Aug 16.

Division of Neonatology, Department of Pediatrics, University of Heidelberg Medical School, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000107350DOI Listing
April 2008

Global gene expression in Ha-ras and B-raf mutated mouse liver tumors.

Int J Cancer 2007 Sep;121(6):1382-5

Department of Toxicology, Institute of Pharmacology and Toxicology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/ijc.22801DOI Listing
September 2007

Proteome analysis of chemically induced mouse liver tumors with different genotype.

Proteomics 2007 Sep;7(18):3318-31

Department of Toxicology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/pmic.200600983DOI Listing
September 2007

Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomas.

Drug Metab Dispos 2007 Apr 12;35(4):503-7. Epub 2007 Jan 12.

Institute of Pharmacology and Toxicology, Department of Toxicology, University of Tuebingen, Wilhelmstr. 56, 72074 Tuebingen, Germany.

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http://dx.doi.org/10.1124/dmd.106.013656DOI Listing
April 2007

Differential gene expression in periportal and perivenous mouse hepatocytes.

FEBS J 2006 Nov 20;273(22):5051-61. Epub 2006 Oct 20.

Institute of Pharmacology and Toxicology, Department of Toxicology, University of Tuebingen, Germany.

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http://dx.doi.org/10.1111/j.1742-4658.2006.05503.xDOI Listing
November 2006

Ablation of gap junctional communication in hepatocytes of transgenic mice does not lead to disrupted cellular homeostasis or increased spontaneous tumourigenesis.

Eur J Cell Biol 2006 Aug 5;85(8):717-28. Epub 2006 Jun 5.

Institut für Genetik, Abteilung Molekulargenetik, Universität Bonn, Römerstr. 164, D-53117 Bonn, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2006.03.004DOI Listing
August 2006

Renal artery stenosis: functional assessment with dynamic MR perfusion measurements--feasibility study.

Radiology 2006 Feb;238(2):586-96

Institute of Clinical Radiology, University Hospitals-Grosshadern, Department of Internal Medicine, Division of Nephrology, Ludwig-Maximilians-University, Marchioninistrasse 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1148/radiol.2382041553DOI Listing
February 2006

Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53.

Carcinogenesis 2005 Oct 25;26(10):1829-34. Epub 2005 May 25.

Department of Toxicology, Institute of Pharmacology and Toxicology, University of Tübingen, Wilhelmstrasse 56, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1093/carcin/bgi142DOI Listing
October 2005

A safety study of oral xanthohumol administration and its influence on fertility in Sprague Dawley rats.

Mol Nutr Food Res 2005 Sep;49(9):861-7

Division of Toxicology and Cancer Risk Factors, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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http://dx.doi.org/10.1002/mnfr.200500089DOI Listing
September 2005

Genotype-phenotype relationships in hepatocellular tumors from mice and man.

Hepatology 2005 Aug;42(2):353-61

Institut für Pharmakologie und Toxikologie, Abteilung Toxikologie, Universität Tübingen, Wilhelmstrasse 56, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1002/hep.20768DOI Listing
August 2005

Patient-based cross-platform comparison of oligonucleotide microarray expression profiles.

Lab Invest 2005 Aug;85(8):1024-39

1Division of Molecular Genetics, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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http://dx.doi.org/10.1038/labinvest.3700293DOI Listing
August 2005

Effect of the tumor promoter phenobarbital on the pattern of global gene expression in liver of connexin32-wild-type and connexin32-deficient mice.

Int J Cancer 2005 Jul;115(6):861-9

Institut für Pharmakologie und Toxikologie, Abteilung Toxikologie, Universität Tübingen, Germany.

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http://dx.doi.org/10.1002/ijc.20815DOI Listing
July 2005

High-spatial-resolution MR angiography of renal arteries with integrated parallel acquisitions: comparison with digital subtraction angiography and US.

Radiology 2005 May 15;235(2):687-98. Epub 2005 Mar 15.

Institute of Clinical Radiology, Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1148/radiol.2352031693DOI Listing
May 2005

Effective transcriptome amplification for expression profiling on sense-oriented oligonucleotide microarrays.

Nucleic Acids Res 2005 Feb 17;33(3):e29. Epub 2005 Feb 17.

Division of Molecular Genetics, Deutsches Krebsforschungszentrum Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/nar/gni029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549428PMC
February 2005

Renal disease: value of functional magnetic resonance imaging with flow and perfusion measurements.

Invest Radiol 2004 Nov;39(11):698-705

Division Oncologic Diagnostics and Therapy, German Cancer Research Center, Ludwig-Maximilians-Universität, Munich, Germany.

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http://dx.doi.org/10.1097/00004424-200411000-00008DOI Listing
November 2004

Nuclear body movement is determined by chromatin accessibility and dynamics.

Proc Natl Acad Sci U S A 2004 Sep 26;101(36):13221-6. Epub 2004 Aug 26.

Division of Molecular Genetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0402958101
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http://dx.doi.org/10.1073/pnas.0402958101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516551PMC
September 2004

A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice.

Cancer Res 2004 Jul;64(14):4707-10

Institut für Pharmakologie und Toxikologie, Abteilung Toxikologie, Universität Tübingen, Wilhelmstrasse 56, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-03-0875DOI Listing
July 2004

Biostatistical methods for the validation of alternative methods for in vitro toxicity testing.

Altern Lab Anim 2003 Jun;31 Suppl 1:5-41

Biostatistics Unit, C060, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1177/026119290303101s02DOI Listing
June 2003