Publications by authors named "Carien L Creutzberg"

96Publications

Adjuvant therapy for endometrial cancer in the era of molecular classification: radiotherapy, chemoradiation and novel targets for therapy.

Int J Gynecol Cancer 2020 Oct 20. Epub 2020 Oct 20.

Department of Radiation Oncology, Leiden University Medical Center Centrum, Leiden, Zuid-Holland, The Netherlands.

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http://dx.doi.org/10.1136/ijgc-2020-001822DOI Listing
October 2020

Efficacy and toxicity of postoperative external beam radiotherapy or chemoradiation for early-stage cervical cancer.

Int J Gynecol Cancer 2020 Jun 25. Epub 2020 Jun 25.

Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/ijgc-2019-001131DOI Listing
June 2020

PARP and PD-1/PD-L1 checkpoint inhibition in recurrent or metastatic endometrial cancer.

Crit Rev Oncol Hematol 2020 Aug 18;152:102973. Epub 2020 May 18.

Departments of Medical Oncology, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.critrevonc.2020.102973DOI Listing
August 2020

Uterine Cancer: Adjuvant Therapy and Management of Metastatic Disease.

J Clin Oncol 2019 09 12;37(27):2490-2500. Epub 2019 Aug 12.

University of Chicago Medical Center, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.19.00037DOI Listing
September 2019

Selecting Adjuvant Treatment for Endometrial Carcinoma Using Molecular Risk Factors.

Curr Oncol Rep 2019 07 31;21(9):83. Epub 2019 Jul 31.

Department of Radiation Oncology, Leiden University Medical Center, K1-P, Albinusdreef 2, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s11912-019-0825-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669195PMC
July 2019

Vulvar malignant melanoma: Pathogenesis, clinical behaviour and management: Review of the literature.

Cancer Treat Rev 2019 Feb 24;73:91-103. Epub 2018 Dec 24.

Department of Gynaecology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2018.12.005DOI Listing
February 2019

Cancer of the corpus uteri.

Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:37-50

Department of Radiation Oncology, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.1002/ijgo.12612DOI Listing
October 2018

Adjuvant therapy for high-risk endometrial cancer: recent evidence and future directions.

Expert Rev Anticancer Ther 2019 01 24;19(1):51-60. Epub 2018 Oct 24.

a Department of Radiation Oncology , Leiden University Medical Center , Leiden , The Netherlands.

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https://www.tandfonline.com/doi/full/10.1080/14737140.2019.1
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http://dx.doi.org/10.1080/14737140.2019.1531708DOI Listing
January 2019

ESGO Survey on Current Practice in the Management of Cervical Cancer.

Int J Gynecol Cancer 2018 07;28(6):1226-1231

Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic.

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http://dx.doi.org/10.1097/IGC.0000000000001314DOI Listing
July 2018

Investigators' response.

Lancet Oncol 2018 05;19(5):602

Department of Radiation Oncology, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.1016/S1470-2045(18)30279-1DOI Listing
May 2018

Ruthenium-106 brachytherapy for iris and iridociliary melanomas.

Br J Ophthalmol 2018 08 9;102(8):1154-1159. Epub 2017 Nov 9.

Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2017-3106
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http://dx.doi.org/10.1136/bjophthalmol-2017-310688DOI Listing
August 2018

Blinded histopathological characterisation of POLE exonuclease domain-mutant endometrial cancers: sheep in wolf's clothing.

Histopathology 2018 Jan 10;72(2):248-258. Epub 2017 Oct 10.

Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/his.13338DOI Listing
January 2018

Reply to M. Wissing et al.

J Clin Oncol 2017 06 13;35(16):1862. Epub 2017 Mar 13.

Lisette M. Wiltink, Remi A. Nout, Marta Fiocco, Carien L. Creutzberg, and Cornelia A.M. Marijnen, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2017.72.6125DOI Listing
June 2017

A Controlled Study on Vaginal Blood Flow During Sexual Arousal Among Early-Stage Cervical Cancer Survivors Treated With Conventional Radical or Nerve-Sparing Surgery With or Without Radiotherapy.

Int J Gynecol Cancer 2017 06;27(5):1051-1057

*Department of Gynecology, Leiden University Medical Center, Leiden; †Department of Gynecology, Amsterdam Medical Center, Amsterdam; and ‡Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1097/IGC.0000000000000986DOI Listing
June 2017

Ruthenium-106 brachytherapy for choroidal melanoma without transpupillary thermotherapy: Similar efficacy with improved visual outcome.

Eur J Cancer 2016 11 12;68:106-113. Epub 2016 Oct 12.

Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.09.009DOI Listing
November 2016

Which cervical and endometrial cancer patients will benefit most from intensity-modulated proton therapy?

Radiother Oncol 2016 09 21;120(3):397-403. Epub 2016 Jul 21.

Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.radonc.2016.06.016DOI Listing
September 2016

Radiation therapy combined with hyperthermia versus cisplatin for locally advanced cervical cancer: Results of the randomized RADCHOC trial.

Radiother Oncol 2016 09 17;120(3):378-382. Epub 2016 Feb 17.

Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands; Department of Hyperthermia, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.radonc.2016.02.010DOI Listing
September 2016

Hyperbaric oxygen therapy for radiation-induced injury: evidence is needed.

Lancet Oncol 2016 Feb 17;17(2):132-134. Epub 2015 Dec 17.

Department of Radiation Oncology, Leiden University Medical Centre, Leiden, Netherlands. Electronic address:

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://linkinghub.elsevier.com/retrieve/pii/S147020451500534
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http://dx.doi.org/10.1016/S1470-2045(15)00534-3DOI Listing
February 2016

Cancer of the corpus uteri.

Int J Gynaecol Obstet 2015 Oct;131 Suppl 2:S96-104

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.ijgo.2015.06.005DOI Listing
October 2015

Groin surgery and risk of recurrence in lymph node positive patients with vulvar squamous cell carcinoma.

Gynecol Oncol 2015 Dec 23;139(3):458-64. Epub 2015 Oct 23.

Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.ygyno.2015.09.081DOI Listing
December 2015

Radiation Treatment Affects Chromosome Testing in Uveal Melanoma.

Invest Ophthalmol Vis Sci 2015 Sep;56(10):5956-64

Department of Ophthalmology Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1167/iovs.15-17092DOI Listing
September 2015

Nomograms for prediction of outcome with or without adjuvant radiation therapy for patients with endometrial cancer: a pooled analysis of PORTEC-1 and PORTEC-2 trials.

Int J Radiat Oncol Biol Phys 2015 Mar 30;91(3):530-9. Epub 2015 Jan 30.

Department of Radiation Oncology, MAASTRO, GROW, University Medical Centre Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.ijrobp.2014.11.022DOI Listing
March 2015

No Increased Risk of Second Cancer After Radiotherapy in Patients Treated for Rectal or Endometrial Cancer in the Randomized TME, PORTEC-1, and PORTEC-2 Trials.

J Clin Oncol 2015 May 22;33(15):1640-6. Epub 2014 Dec 22.

Lisette M. Wiltink, Remi A. Nout, Marta Fiocco, Elma Meershoek-Klein Kranenbarg, Cornelis J.H. van de Velde, Carien L. Creutzberg, and Corrie A.M. Marijnen, Leiden University Medical Center, Leiden; Ina M. Jürgenliemk-Schulz, University Medical Center Utrecht, Utrecht; Jan J. Jobsen, Medisch Spectum Twente, Enschede; Iris D. Nagtegaal, Radboud University Medical Center, Nijmegen; and Harm J.T. Rutten, Catharina Hospital Eindhoven, Eindhoven, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2014.58.6693DOI Listing
May 2015

Prognostic significance of POLE proofreading mutations in endometrial cancer.

J Natl Cancer Inst 2015 Jan 12;107(1):402. Epub 2014 Dec 12.

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (DNC, IPMT); Oxford Cancer Centre, Churchill Hospital, Oxford, UK (DNC); Department of Pathology (ES, NtH, VTHBMS, TB) and Department of Clinical Oncology (RAN, CLC), Leiden University Medical Center, Leiden, the Netherlands; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland (NV, AN, PJW); Vesalius Research Center (VRC), VIB, Leuven, Belgium (JD, DL); Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Belgium (FA, DL); Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, University Hospitals Gasthuisberg, Leuven, Belgium (FA); Genomic Medicine Theme, Oxford Comprehensive Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (IPMT); Department of Radiation Oncology, University Medical Centrum Utrecht, the Netherlands (IMJS); Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, the Netherlands (JJJ).

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http://dx.doi.org/10.1093/jnci/dju402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301706PMC
January 2015

Qualitative accounts of patients' determinants of vaginal dilator use after pelvic radiotherapy.

J Sex Med 2015 Mar 25;12(3):764-73. Epub 2014 Nov 25.

Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jsm.12776DOI Listing
March 2015

Gynecologic Cancer InterGroup (GCIG) consensus review for uterine serous carcinoma.

Int J Gynecol Cancer 2014 Nov;24(9 Suppl 3):S83-9

*Department of Obstetrics & Gynecology, JR Sapporo Hospital, Sapporo, Japan; †Department of Obstetrics & Gynecology, School of Medicine, Keio University, Tokyo; ‡Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA; §Department of Obstetrics and Gynecology, Ohio State University College of Medicine, Columbus, OH; ∥Centre Hospitalier de L'Université de Montréal, Montreal, Quebec, Canada; ¶Oncology Department, Christchurch Hospital, Canterbury, New Zealand; #Department of Clinical Oncology, Leiden University Medical Center, Leiden, the Netherlands; **Department Gynecology & Gynecologic Oncology, Kliniken Essen Mitte (KEM) (AGO), Essen, Germany; ††Norwegian Radium Hospital, Oslo, Norway; ‡‡Department of Obstetrics and Gynecology, Inje University Sanggye Paik Hospital, Seoul, South Korea; §§Department of Oncology and Hematology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; ∥∥Beatson West of Scotland Cancer Centre, Glasgow, Scotland; and ¶¶Department of Radiation Oncology, Stritch School of Medicine Loyola University, Chicago, IL.

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http://pdfs.journals.lww.com/ijgc/2014/11003/Gynecologic_Can
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http://dx.doi.org/10.1097/IGC.0000000000000264DOI Listing
November 2014

Gynecologic Cancer InterGroup (GCIG) consensus review for uterine and ovarian carcinosarcoma.

Int J Gynecol Cancer 2014 Nov;24(9 Suppl 3):S55-60

*ICO Centre René Gauducheau, Saint Herblain; †Hôpital de la Croix Rousse, Lyon, France; ‡UCL Cancer Institute, London, United Kingdom; §Memorial Sloan-Kettering Cancer Center, New York, NY; ∥Washington University School of Medicine, St Louis, MO; ¶Fundacion Instituto Valenciano de Oncologia, Valencia, Spain; #Sydney Local Health District, Sydney, Australia; **Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom; ††Leiden University Medical Center, Leiden, the Netherlands; ‡‡Kliniken-Essen-Mitte, Essen, Germany; §§Seoul National University College of Medicine, Seoul, Republic of Korea; ∥∥Beatson Oncology Centre, Glasgow, United Kingdom; and ¶¶Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1097/IGC.0000000000000228DOI Listing
November 2014

Sexual rehabilitation after pelvic radiotherapy and vaginal dilator use: consensus using the Delphi method.

Int J Gynecol Cancer 2014 Oct;24(8):1499-506

Departments of *Gynecology, and †Clinical Oncology, Leiden University Medical Center, Leiden; and Departments of ‡Radiotherapy, and §Gynecology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.

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http://pdfs.journals.lww.com/ijgc/2014/10000/Sexual_Rehabili
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0000000000000253DOI Listing
October 2014

Psychosexual support for gynecological cancer survivors: professionals' current practices and need for assistance.

Support Care Cancer 2015 Mar 14;23(3):831-9. Epub 2014 Sep 14.

Department of Gynecology, Leiden University Medical Center, P.O. BOX 9600, 2300 RC, Leiden, The Netherlands,

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http://dx.doi.org/10.1007/s00520-014-2433-7DOI Listing
March 2015

Impact of cardiovascular counseling and screening in Hodgkin lymphoma survivors.

Int J Radiat Oncol Biol Phys 2014 Sep;90(1):164-71

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.ijrobp.2014.05.038DOI Listing
September 2014

Second primary cancers in survivors of cervical cancer in The Netherlands: Implications for prevention and surveillance.

Radiother Oncol 2014 Jun 12;111(3):374-81. Epub 2014 May 12.

Section of Cancer Information, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1016/j.radonc.2014.04.011DOI Listing
June 2014

High concordance of molecular tumor alterations between pre-operative curettage and hysterectomy specimens in patients with endometrial carcinoma.

Gynecol Oncol 2014 May 18;133(2):197-204. Epub 2014 Feb 18.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2014.02.012DOI Listing
May 2014

Gynecologic Cancer InterGroup (GCIG) Endometrial Cancer Clinical Trials Planning Meeting: taking endometrial cancer trials into the translational era.

Int J Gynecol Cancer 2013 Oct;23(8):1528-34

*Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands; †Institute of Cancer Sciences, University of Manchester, United Kingdom; ‡Division of Hematology and Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA; §Division of Gynaecology, European Institute of Oncology, Milan, Italy; ∥Department of Gynecologic Oncology and Reproductive Medicine, MD Anderson Cancer Center, Houston, TX; ¶Department of Clinical Oncology, Barts Health NHS Trust, London, United Kingdom; #Department of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY; **Department of Gynaecology, Newcastle University and Northern Institute for Cancer Research, Newcastle upon Tyne, United Kingdom; ††Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, OH; ‡‡Department of Gynaecologic Oncology, Royal Women's Hospital, and Melbourne University Dept of Obstetrics and Gynaecology, Australia; §§Department of Obstetrics and Gynecology, Haukeland University Hospital; and Department of Clinical Medicine, University of Bergen, Norway; and ∥∥Department of Radiation Oncology, Sunnybrook Cancer Center, Toronto, Canada.

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http://dx.doi.org/10.1097/IGC.0b013e3182a26edbDOI Listing
October 2013

Long-term risk of secondary skin cancers after radiation therapy for Hodgkin's lymphoma.

Radiother Oncol 2013 Oct 7;109(1):140-5. Epub 2013 Aug 7.

Department of Clinical Oncology, Leiden University Medical Center, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2013.06.041DOI Listing
October 2013

Persisting fatigue in Hodgkin lymphoma survivors: a systematic review.

Ann Hematol 2013 Aug 1;92(8):1023-32. Epub 2013 Jun 1.

Departments of Clinical Oncology, K1-P, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00277-013-1793-2DOI Listing
August 2013

Cancer of the corpus uteri.

Int J Gynaecol Obstet 2012 Oct;119 Suppl 2:S110-7

Division of Gynecologic Oncology, University Hospitals Gasthuisberg, Leuven, Belgium.

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http://dx.doi.org/10.1016/S0020-7292(12)60024-1DOI Listing
October 2012

Long-term clinical outcome of patients with soft tissue sarcomas treated with limb-sparing surgery and postoperative radiotherapy.

Acta Oncol 2013 May 30;52(4):745-52. Epub 2012 Aug 30.

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.3109/0284186X.2012.709947DOI Listing
May 2013

The role of radiotherapy in endometrial cancer: current evidence and trends.

Curr Oncol Rep 2011 Dec;13(6):472-8

Department of Clinical Oncology, Leiden University Medical Center, The Netherlands.

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http://link.springer.com/10.1007/s11912-011-0191-y
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http://dx.doi.org/10.1007/s11912-011-0191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212694PMC
December 2011

Adjuvant chemotherapy for endometrial cancer: unproven.

Int J Gynecol Cancer 2010 Oct;20(7):1105-8

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/igc.0b013e3181f35473DOI Listing
October 2010

Point: Vaginal brachytherapy should be a standard adjuvant treatment for intermediate-risk endometrial cancer.

Brachytherapy 2011 Jan-Feb;10(1):1-3

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S15384721100034
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http://dx.doi.org/10.1016/j.brachy.2010.11.002DOI Listing
April 2011

International brachytherapy practice patterns: a survey of the Gynecologic Cancer Intergroup (GCIG).

Int J Radiat Oncol Biol Phys 2012 Jan 22;82(1):250-5. Epub 2010 Dec 22.

Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2010.10.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489266PMC
January 2012

Adjuvant chemotherapy for endometrial cancer: unproven.

Int J Gynecol Cancer 2010 Oct;20(11 Suppl 2):S60-3

Department of Clinical Oncology, Leiden University Medical Center, RC Leiden, The Netherlands.

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http://dx.doi.org/10.1111/IGC.0b013e3181f60af6DOI Listing
October 2010

Ruthenium plaque radiation therapy for iris and iridociliary melanomas.

Acta Ophthalmol 2012 May 29;90(3):291-6. Epub 2010 Jul 29.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/j.1755-3768.2010.01967.xDOI Listing
May 2012

Long-term outcomes of eye-conserving treatment with Ruthenium(106) brachytherapy for choroidal melanoma.

Radiother Oncol 2010 Jun 21;95(3):332-8. Epub 2010 Apr 21.

Department of Radiation Oncology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.radonc.2010.03.023DOI Listing
June 2010

Efficacy of a hypofractionated schedule in electron beam radiotherapy for epithelial skin cancer: Analysis of 434 cases.

Radiother Oncol 2010 May 23;95(2):245-9. Epub 2010 Mar 23.

Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.radonc.2010.02.024DOI Listing
May 2010

Lymphadenectomy in apparent early-stage endometrial carcinoma: do numbers count?

J Clin Oncol 2005 Jun 28;23(16):3653-5. Epub 2005 Feb 28.

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http://dx.doi.org/10.1200/JCO.2005.11.947DOI Listing
June 2005

Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma.

Cancer 2004 Feb;100(4):764-72

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/cncr.20040DOI Listing
February 2004

Long-term outcome in endometrial carcinoma favors a two- instead of a three-tiered grading system.

Int J Radiat Oncol Biol Phys 2002 Mar;52(4):1067-74

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/s0360-3016(01)02710-9DOI Listing
March 2002