Carel B Hoyng

Carel B Hoyng

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Carel B Hoyng

Publications by authors named "Carel B Hoyng"

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Patient characteristics of untreated chronic central serous chorioretinopathy patients with focal versus diffuse leakage.

Graefes Arch Clin Exp Ophthalmol 2019 Jul 23;257(7):1419-1425. Epub 2019 May 23.

Department of Ophthalmology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00417-019-04333-yDOI Listing
July 2019

Central serous chorioretinopathy: Towards an evidence-based treatment guideline.

Prog Retin Eye Res 2019 Jul 15. Epub 2019 Jul 15.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Department of Ophthalmology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.preteyeres.2019.07.003DOI Listing
July 2019

The absence of fundus abnormalities in Stargardt disease.

Graefes Arch Clin Exp Ophthalmol 2019 Jun 22;257(6):1147-1157. Epub 2019 Mar 22.

Department of Ophthalmology (400), Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/s00417-019-04280-8
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http://dx.doi.org/10.1007/s00417-019-04280-8DOI Listing
June 2019

The identification of a RNA splice variant in TULP1 in two siblings with early-onset photoreceptor dystrophy.

Mol Genet Genomic Med 2019 Jun 4;7(6):e660. Epub 2019 Apr 4.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mgg3.660
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http://dx.doi.org/10.1002/mgg3.660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565574PMC
June 2019

Exome sequencing in families with chronic central serous chorioretinopathy.

Mol Genet Genomic Med 2019 04 6;7(4):e00576. Epub 2019 Feb 6.

Department of Ophthalmology, Donders Institute of Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mgg3.576
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http://dx.doi.org/10.1002/mgg3.576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465660PMC
April 2019

Reply.

Ophthalmology 2019 Apr;126(4):e30-e31

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Department of Ophthalmology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2018.11.005DOI Listing
April 2019

Focal and diffuse chronic central serous chorioretinopathy treated with half-dose photodynamic therapy or subthreshold micropulse laser.

Am J Ophthalmol 2019 Apr 2. Epub 2019 Apr 2.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Amsterdam UMC, University of Amsterdam, Department of Ophthalmology, Meibergdreef 9, Amsterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajo.2019.03.025DOI Listing
April 2019

Exome sequencing in patients with chronic central serous chorioretinopathy.

Sci Rep 2019 Apr 29;9(1):6598. Epub 2019 Apr 29.

Department of Ophthalmology, Donders Institute of Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-43152-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488596PMC
April 2019

Validation of a model for the prediction of retinopathy in persons with type 1 diabetes.

Br J Ophthalmol 2019 Mar 1. Epub 2019 Mar 1.

Department of General Practice and Elderly Care Medicine, Amsterdam Public Health Research Institute, VU Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/bjophthalmol-2018-313539DOI Listing
March 2019

FAMILIAL CENTRAL SEROUS CHORIORETINOPATHY.

Retina 2019 Feb;39(2):398-407

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1097/IAE.0000000000001966DOI Listing
February 2019

Reply.

Ophthalmology 2019 Jan 22;126(1):e11. Epub 2018 Nov 22.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2018.06.038DOI Listing
January 2019

Genetic screening for macular dystrophies in patients clinically diagnosed with dry age-related macular degeneration.

Clin Genet 2018 Dec 15;94(6):569-574. Epub 2018 Oct 15.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1111/cge.13447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282796PMC
December 2018

Geographic distribution of rare variants associated with age-related macular degeneration.

Mol Vis 2018 27;24:75-82. Epub 2018 Jan 27.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788811PMC
November 2018

Half-Dose Photodynamic Therapy versus High-Density Subthreshold Micropulse Laser Treatment in Patients with Chronic Central Serous Chorioretinopathy: The PLACE Trial.

Ophthalmology 2018 Oct 14;125(10):1547-1555. Epub 2018 Jun 14.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2018.04.021DOI Listing
October 2018

Homozygous variants in , encoding a ciliary protein, are associated with autosomal recessive retinitis pigmentosa.

J Med Genet 2018 Oct 17;55(10):705-712. Epub 2018 Aug 17.

Department of Human Genetics, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1136/jmedgenet-2018-105364DOI Listing
October 2018

SHORT-TERM FINDINGS ON OPTICAL COHERENCE TOMOGRAPHY AND MICROPERIMETRY IN CHRONIC CENTRAL SEROUS CHORIORETINOPATHY PATIENTS TREATED WITH HALF-DOSE PHOTODYNAMIC THERAPY.

Retin Cases Brief Rep 2018 Fall;12(4):266-271

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1097/ICB.0000000000000498DOI Listing
September 2018

Non-syndromic retinitis pigmentosa.

Prog Retin Eye Res 2018 09 27;66:157-186. Epub 2018 Mar 27.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.preteyeres.2018.03.005DOI Listing
September 2018

Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch's Membrane.

Ophthalmology 2018 Sep 26;125(9):1433-1443. Epub 2018 Apr 26.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2018.03.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104593PMC
September 2018

Risk factors for development and progression of diabetic retinopathy in Dutch patients with type 1 diabetes mellitus.

Acta Ophthalmol 2018 Aug;96(5):459-464

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/aos.13815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174939PMC
August 2018

Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.

Ophthalmology 2018 Jul 2;125(7):1064-1074. Epub 2018 Feb 2.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2017.12.023DOI Listing
July 2018

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse.

Am J Hum Genet 2018 07 28;103(1):74-88. Epub 2018 Jun 28.

Hearing and Genes Division, Department of Otorhinolaryngology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037131PMC
July 2018

ADALIMUMAB THERAPY FOR REFRACTORY BIRDSHOT CHORIORETINOPATHY.

Retina 2018 Jul 31. Epub 2018 Jul 31.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/IAE.0000000000002281DOI Listing
July 2018

Morphological and topographical appearance of microaneurysms on optical coherence tomography angiography.

Br J Ophthalmol 2018 Jun 20. Epub 2018 Jun 20.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands

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http://dx.doi.org/10.1136/bjophthalmol-2018-312258DOI Listing
June 2018

Variants in the PRPF8 Gene are Associated with Glaucoma.

Mol Neurobiol 2018 May 13;55(5):4504-4510. Epub 2017 Jul 13.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s12035-017-0673-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884903PMC
May 2018

Functional analyses of rare genetic variants in complement component C9 identified in patients with age-related macular degeneration.

Hum Mol Genet 2018 May 14. Epub 2018 May 14.

Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö 214 28, Sweden.

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http://dx.doi.org/10.1093/hmg/ddy178DOI Listing
May 2018

Identification and Rescue of Splice Defects Caused by Two Neighboring Deep-Intronic ABCA4 Mutations Underlying Stargardt Disease.

Am J Hum Genet 2018 04 8;102(4):517-527. Epub 2018 Mar 8.

Department of Human Genetics, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 EN Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985352PMC
April 2018

Identification of TP53BP2 as a Novel Candidate Gene for Primary Open Angle Glaucoma by Whole Exome Sequencing in a Large Multiplex Family.

Mol Neurobiol 2018 02 1;55(2):1387-1395. Epub 2017 Feb 1.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://link.springer.com/10.1007/s12035-017-0403-z
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http://dx.doi.org/10.1007/s12035-017-0403-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820370PMC
February 2018

Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration.

Surv Ophthalmol 2018 Jan - Feb;63(1):9-39. Epub 2017 May 15.

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.survophthal.2017.05.003DOI Listing
December 2017

Spectrum of retinal abnormalities in renal transplant patients using chronic low-dose steroids.

Graefes Arch Clin Exp Ophthalmol 2017 Dec 23;255(12):2443-2449. Epub 2017 Oct 23.

Department of Ophthalmology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.

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http://dx.doi.org/10.1007/s00417-017-3823-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696484PMC
December 2017

Phenotype Characteristics of Patients With Age-Related Macular Degeneration Carrying a Rare Variant in the Complement Factor H Gene.

JAMA Ophthalmol 2017 10;135(10):1037-1044

Department of Ophthalmology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1001/jamaophthalmol.2017.3195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710490PMC
October 2017

Aberrant leukocyte telomere length in Birdshot Uveitis.

PLoS One 2017 1;12(5):e0176175. Epub 2017 May 1.

Laboratory of Translational Immunology, department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176175PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411068PMC
September 2017

Switching to aflibercept in patients with neovascular age-related macular degeneration not responding to bevacizumab: a pilot study.

Acta Ophthalmol 2017 08 27;95(5):e426-e427. Epub 2016 Jun 27.

Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/aos.13146DOI Listing
August 2017

Physical Activity and Age-related Macular Degeneration: A Systematic Literature Review and Meta-analysis.

Am J Ophthalmol 2017 Aug 24;180:29-38. Epub 2017 May 24.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital & Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Australia; Department of Ophthalmology, University of Bonn, Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029394173021
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http://dx.doi.org/10.1016/j.ajo.2017.05.016DOI Listing
August 2017

Alteration of retinal layers in healthy subjects over 60 years of age until nonagenarians.

Clin Ophthalmol 2017 16;11:1499-1503. Epub 2017 Aug 16.

Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.2147/OPTH.S137223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566895PMC
August 2017

Measurement and Reproducibility of Preserved Ellipsoid Zone Area and Preserved Retinal Pigment Epithelium Area in Eyes With Choroideremia.

Am J Ophthalmol 2017 Jul 10;179:110-117. Epub 2017 May 10.

Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, California; Department of Ophthalmology, David Geffen School of Medicine of the University of California-Los Angeles, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.ajo.2017.05.002DOI Listing
July 2017

Genotypic and Phenotypic Characteristics of CRB1-Associated Retinal Dystrophies: A Long-Term Follow-up Study.

Ophthalmology 2017 06 21;124(6):884-895. Epub 2017 Mar 21.

Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands; Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2017.01.047DOI Listing
June 2017

In Silico Functional Meta-Analysis of 5,962 ABCA4 Variants in 3,928 Retinal Dystrophy Cases.

Hum Mutat 2017 04 3;38(4):400-408. Epub 2017 Feb 3.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/humu.23165DOI Listing
April 2017

Automated Staging of Age-Related Macular Degeneration Using Optical Coherence Tomography.

Invest Ophthalmol Vis Sci 2017 04;58(4):2318-2328

Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands 2Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1167/iovs.16-20541DOI Listing
April 2017

Rare and low-frequency coding variants alter human adult height.

Authors:
Eirini Marouli Mariaelisa Graff Carolina Medina-Gomez Ken Sin Lo Andrew R Wood Troels R Kjaer Rebecca S Fine Yingchang Lu Claudia Schurmann Heather M Highland Sina Rüeger Gudmar Thorleifsson Anne E Justice David Lamparter Kathleen E Stirrups Valérie Turcot Kristin L Young Thomas W Winkler Tõnu Esko Tugce Karaderi Adam E Locke Nicholas G D Masca Maggie C Y Ng Poorva Mudgal Manuel A Rivas Sailaja Vedantam Anubha Mahajan Xiuqing Guo Goncalo Abecasis Katja K Aben Linda S Adair Dewan S Alam Eva Albrecht Kristine H Allin Matthew Allison Philippe Amouyel Emil V Appel Dominique Arveiler Folkert W Asselbergs Paul L Auer Beverley Balkau Bernhard Banas Lia E Bang Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Heiner Boeing Eric Boerwinkle Carsten A Böger Lori L Bonnycastle Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Amber A Burt Adam S Butterworth David J Carey Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox Gabriel Cuellar-Partida John Danesh Gail Davies Paul I W de Bakker Gert J de Borst Simon de Denus Mark C H de Groot Renée de Mutsert Ian J Deary George Dedoussis Ellen W Demerath Anneke I den Hollander Joe G Dennis Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Alison M Dunning Douglas F Easton Tapani Ebeling Todd L Edwards Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki Jessica D Faul Mary F Feitosa Shuang Feng Ele Ferrannini Marco M Ferrario Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Paul W Franks Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Ayush Giri Giorgia Girotto Scott D Gordon Penny Gordon-Larsen Mathias Gorski Niels Grarup Megan L Grove Vilmundur Gudnason Stefan Gustafsson Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Caroline Hayward Liang He Iris M Heid Kauko Heikkilä Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Lynne J Hocking Mette Hollensted Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Carel B Hoyng Paul L Huang Kristian Hveem M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Min A Jhun Yucheng Jia Xuejuan Jiang Stefan Johansson Marit E Jørgensen Torben Jørgensen Pekka Jousilahti J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Frank Kee Renske Keeman Lambertus A Kiemeney Hidetoshi Kitajima Kirsten B Kluivers Thomas Kocher Pirjo Komulainen Jukka Kontto Jaspal S Kooner Charles Kooperberg Peter Kovacs Jennifer Kriebel Helena Kuivaniemi Sébastien Küry Johanna Kuusisto Martina La Bianca Markku Laakso Timo A Lakka Ethan M Lange Leslie A Lange Carl D Langefeld Claudia Langenberg Eric B Larson I-Te Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Yeheng Liu Yongmei Liu Artitaya Lophatananon Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen David A Mackey Pamela A F Madden Alisa K Manning Satu Männistö Gaëlle Marenne Jonathan Marten Nicholas G Martin Angela L Mazul Karina Meidtner Andres Metspalu Paul Mitchell Karen L Mohlke Dennis O Mook-Kanamori Anna Morgan Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Matthias Nauck Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Ioanna Ntalla Jeffrey R O'Connel Heikki Oksa Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Thomas N Person Ailith Pirie Ozren Polasek Danielle Posthuma Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Paul M Ridker John D Rioux Neil Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Kevin Sandow Yadav Sapkota Naveed Sattar Marjanka K Schmidt Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati Shah Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert Vernon Smith Jennifer A Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Valgerdur Steinthorsdottir Heather M Stringham Michael Stumvoll Praveen Surendran Leen M 't Hart Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Sheila Ulivi Sander W van der Laan Andries R Van Der Leij Cornelia M van Duijn Natasja M van Schoor Jessica van Setten Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Henrik Vestergaard Veronique Vitart Thomas F Vogt Diego Vozzi Mark Walker Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Nicholas J Wareham Helen R Warren Jennifer Wessel Sara M Willems James G Wilson Daniel R Witte Michael O Woods Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao He Zheng Wei Zhou Jerome I Rotter Michael Boehnke Sekar Kathiresan Mark I McCarthy Cristen J Willer Kari Stefansson Ingrid B Borecki Dajiang J Liu Kari E North Nancy L Heard-Costa Tune H Pers Cecilia M Lindgren Claus Oxvig Zoltán Kutalik Fernando Rivadeneira Ruth J F Loos Timothy M Frayling Joel N Hirschhorn Panos Deloukas Guillaume Lettre

Nature 2017 02 1;542(7640):186-190. Epub 2017 Feb 1.

Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.

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http://dx.doi.org/10.1038/nature21039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302847PMC
February 2017

The Functional Effect of Rare Variants in Complement Genes on C3b Degradation in Patients With Age-Related Macular Degeneration.

JAMA Ophthalmol 2017 Jan;135(1):39-46

Department of Ophthalmology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands4Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1001/jamaophthalmol.2016.4604DOI Listing
January 2017

Multimodal imaging of the disease progression of birdshot chorioretinopathy.

Acta Ophthalmol 2016 Dec 27;94(8):815-823. Epub 2016 May 27.

Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1111/aos.13114DOI Listing
December 2016

Asymmetric Inter-Eye Progression in Stargardt Disease.

Invest Ophthalmol Vis Sci 2016 12;57(15):6824-6830

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1167/iovs.16-20963DOI Listing
December 2016

Corrigendum to "Nutritional Risk Factors for Age-Related Macular Degeneration".

Biomed Res Int 2016;2016:7589328. Epub 2016 Nov 3.

Department of Ophthalmology, University Hospital of Cologne, Kerpener Straße 62, 50924 Cologne, Germany.

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http://dx.doi.org/10.1155/2016/7589328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112324PMC
November 2016

Carbonic Anhydrase Inhibitors for the Treatment of Cystic Macular Lesions in Children With X-Linked Juvenile Retinoschisis.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5143-5147

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1167/iovs.16-20078DOI Listing
October 2016

Progression of Late-Onset Stargardt Disease.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5186-5191

Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1167/iovs.16-19833DOI Listing
October 2016

Efficacy of photodynamic therapy in steroid-associated chronic central serous chorioretinopathy: a case-control study.

Acta Ophthalmol 2016 Sep 6;94(6):565-72. Epub 2016 May 6.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/aos.13059DOI Listing
September 2016

Visual Rehabilitation in Chronic Cerebral Blindness: A Randomized Controlled Crossover Study.

Front Neurol 2016 17;7:92. Epub 2016 Jun 17.

Section of Biophysics, Department of Cognitive Neuroscience, Donders Centre for Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Centre , Nijmegen , Netherlands.

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http://dx.doi.org/10.3389/fneur.2016.00092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911356PMC
July 2016

Photoreceptor Progenitor mRNA Analysis Reveals Exon Skipping Resulting from the ABCA4 c.5461-10T→C Mutation in Stargardt Disease.

Ophthalmology 2016 06 12;123(6):1375-85. Epub 2016 Mar 12.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Institute of Molecular Life Sciences, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2016.01.053DOI Listing
June 2016

HISTORY OF SUNLIGHT EXPOSURE IS A RISK FACTOR FOR AGE-RELATED MACULAR DEGENERATION.

Retina 2016 Apr;36(4):787-90

*Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany; and †Department of Ophthalmology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/IAE.0000000000000756DOI Listing
April 2016

Rare Genetic Variants Associated With Development of Age-Related Macular Degeneration.

JAMA Ophthalmol 2016 Mar;134(3):287-93

Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands5Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1001/jamaophthalmol.2015.5592DOI Listing
March 2016

Automatic differentiation of color fundus images containing drusen or exudates using a contextual spatial pyramid approach.

Biomed Opt Express 2016 Mar 2;7(3):709-25. Epub 2016 Feb 2.

Diagnostic Image Analysis Group, Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1364/BOE.7.000709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866450PMC
March 2016

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

Authors:
Lars G Fritsche Wilmar Igl Jessica N Cooke Bailey Felix Grassmann Sebanti Sengupta Jennifer L Bragg-Gresham Kathryn P Burdon Scott J Hebbring Cindy Wen Mathias Gorski Ivana K Kim David Cho Donald Zack Eric Souied Hendrik P N Scholl Elisa Bala Kristine E Lee David J Hunter Rebecca J Sardell Paul Mitchell Joanna E Merriam Valentina Cipriani Joshua D Hoffman Tina Schick Yara T E Lechanteur Robyn H Guymer Matthew P Johnson Yingda Jiang Chloe M Stanton Gabriëlle H S Buitendijk Xiaowei Zhan Alan M Kwong Alexis Boleda Matthew Brooks Linn Gieser Rinki Ratnapriya Kari E Branham Johanna R Foerster John R Heckenlively Mohammad I Othman Brendan J Vote Helena Hai Liang Emmanuelle Souzeau Ian L McAllister Timothy Isaacs Janette Hall Stewart Lake David A Mackey Ian J Constable Jamie E Craig Terrie E Kitchner Zhenglin Yang Zhiguang Su Hongrong Luo Daniel Chen Hong Ouyang Ken Flagg Danni Lin Guanping Mao Henry Ferreyra Klaus Stark Claudia N von Strachwitz Armin Wolf Caroline Brandl Guenther Rudolph Matthias Olden Margaux A Morrison Denise J Morgan Matthew Schu Jeeyun Ahn Giuliana Silvestri Evangelia E Tsironi Kyu Hyung Park Lindsay A Farrer Anton Orlin Alexander Brucker Mingyao Li Christine A Curcio Saddek Mohand-Saïd José-Alain Sahel Isabelle Audo Mustapha Benchaboune Angela J Cree Christina A Rennie Srinivas V Goverdhan Michelle Grunin Shira Hagbi-Levi Peter Campochiaro Nicholas Katsanis Frank G Holz Frédéric Blond Hélène Blanché Jean-François Deleuze Robert P Igo Barbara Truitt Neal S Peachey Stacy M Meuer Chelsea E Myers Emily L Moore Ronald Klein Michael A Hauser Eric A Postel Monique D Courtenay Stephen G Schwartz Jaclyn L Kovach William K Scott Gerald Liew Ava G Tan Bamini Gopinath John C Merriam R Theodore Smith Jane C Khan Humma Shahid Anthony T Moore J Allie McGrath Reneé Laux Milam A Brantley Anita Agarwal Lebriz Ersoy Albert Caramoy Thomas Langmann Nicole T M Saksens Eiko K de Jong Carel B Hoyng Melinda S Cain Andrea J Richardson Tammy M Martin John Blangero Daniel E Weeks Bal Dhillon Cornelia M van Duijn Kimberly F Doheny Jane Romm Caroline C W Klaver Caroline Hayward Michael B Gorin Michael L Klein Paul N Baird Anneke I den Hollander Sascha Fauser John R W Yates Rando Allikmets Jie Jin Wang Debra A Schaumberg Barbara E K Klein Stephanie A Hagstrom Itay Chowers Andrew J Lotery Thierry Léveillard Kang Zhang Murray H Brilliant Alex W Hewitt Anand Swaroop Emily Y Chew Margaret A Pericak-Vance Margaret DeAngelis Dwight Stambolian Jonathan L Haines Sudha K Iyengar Bernhard H F Weber Gonçalo R Abecasis Iris M Heid

Nat Genet 2016 Feb 21;48(2):134-43. Epub 2015 Dec 21.

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.3448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745342PMC
February 2016

A genetic variant in NRP1 is associated with worse response to ranibizumab treatment in neovascular age-related macular degeneration.

Pharmacogenet Genomics 2016 Jan;26(1):20-7

Departments of aOphthalmology bHealth Sciences cHuman Genetics, Radboud university medical center, Nijmegen, The Netherlands dDepartment of Ophthalmology, University Hospital of Cologne, Cologne, Germany eMontreal Retina Institute, Westmount Departments of fOphthalmology gPediatric Surgery, Human Genetics, and Ophthalmology, McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1097/FPC.0000000000000180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890827PMC
January 2016

Genetic Variants and Systemic Complement Activation Levels Are Associated With Serum Lipoprotein Levels in Age-Related Macular Degeneration.

Invest Ophthalmol Vis Sci 2015 Dec;56(13):7766-73

Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands 2Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands 5Department of Human Genetics, Radboud University Medica.

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http://dx.doi.org/10.1167/iovs.15-17035DOI Listing
December 2015

Phenotype Characteristics of Fellow Eyes in Patients With Early Onset of Neovascular Age-Related Macular Degeneration.

Invest Ophthalmol Vis Sci 2015 Nov;56(12):7269-73

Department of Ophthalmology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1167/iovs.15-16989DOI Listing
November 2015

Reply: To PMID 25267528.

Ophthalmology 2015 Oct;122(10):e60

Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2015.04.003DOI Listing
October 2015

Genomic Copy Number Variations of the Complement Component C4B Gene Are Associated With Chronic Central Serous Chorioretinopathy.

Invest Ophthalmol Vis Sci 2015 Aug;56(9):5608-13

Department of Ophthalmology Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1167/iovs.15-17343DOI Listing
August 2015