Caleb J Bashor

Caleb J Bashor

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Caleb J Bashor

Caleb J Bashor

Publications by authors named "Caleb J Bashor"

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16Publications

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Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies.

Science 2019 05 18;364(6440):593-597. Epub 2019 Apr 18.

Department of Biomedical Engineering and Biological Design Center, Boston University, Boston, MA 02215, USA.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aau8287
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http://dx.doi.org/10.1126/science.aau8287DOI Listing
May 2019

Designing Automated, High-throughput, Continuous Cell Growth Experiments Using eVOLVER.

J Vis Exp 2019 May 19(147). Epub 2019 May 19.

Biological Design Center, Boston University; Department of Biomedical Engineering, Boston University; Wyss Institute for Biologically Inspired Engineering, Harvard University;

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http://dx.doi.org/10.3791/59652DOI Listing
May 2019

The Least Mating Pathway: Synthetically Refactoring a Familiar Signaling System for New Applications.

Cell 2019 Apr;177(3):521-523

Department of Bioengineering, Rice University, Houston, TX 77030, USA; Department of Biosciences, Rice University, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.04.003DOI Listing
April 2019

Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER.

Nat Biotechnol 2018 08 11;36(7):614-623. Epub 2018 Jun 11.

Biological Design Center, Boston University, Boston, Massachusetts, USA.

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http://www.nature.com/articles/nbt.4151
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http://dx.doi.org/10.1038/nbt.4151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035058PMC
August 2018

Understanding Biological Regulation Through Synthetic Biology.

Annu Rev Biophys 2018 05 16;47:399-423. Epub 2018 Mar 16.

Institute for Medical Engineering and Science, Department of Biological Engineering, and Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA; email: ,

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http://dx.doi.org/10.1146/annurev-biophys-070816-033903DOI Listing
May 2018

Engineering dynamical control of cell fate switching using synthetic phospho-regulons.

Proc Natl Acad Sci U S A 2016 11 7;113(47):13528-13533. Epub 2016 Nov 7.

Howard Hughes Medical Institute, San Francisco, CA 94158;

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http://dx.doi.org/10.1073/pnas.1610973113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127309PMC
November 2016

'Deadman' and 'Passcode' microbial kill switches for bacterial containment.

Nat Chem Biol 2016 Feb 7;12(2):82-6. Epub 2015 Dec 7.

Institute for Medical Engineering &Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nchembio.1979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718764PMC
February 2016

Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation.

Cell 2014 Jul;158(1):110-20

Department of Biomedical Engineering and Center of Synthetic Biology, Boston University, Boston, MA 02215, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140067
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http://dx.doi.org/10.1016/j.cell.2014.04.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110908PMC
July 2014

A brief history of synthetic biology.

Nat Rev Microbiol 2014 05 1;12(5):381-90. Epub 2014 Apr 1.

1] Howard Hughes Medical Institute, the Center of Synthetic Biology and the Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA. [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nrmicro3239DOI Listing
May 2014

Insulating gene circuits from context by RNA processing.

Nat Biotechnol 2012 Nov;30(11):1061-2

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http://www.nature.com/articles/nbt.2411
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http://dx.doi.org/10.1038/nbt.2411DOI Listing
November 2012

A synthetic biology framework for programming eukaryotic transcription functions.

Cell 2012 Aug;150(3):647-58

Howard Hughes Medical Institute, Department of Biomedical Engineering, and Center for BioDynamics, Boston University, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.cell.2012.05.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653585PMC
August 2012

SYNZIP protein interaction toolbox: in vitro and in vivo specifications of heterospecific coiled-coil interaction domains.

ACS Synth Biol 2012 Apr;1(4):118-29

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1021/sb200015uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339576PMC
April 2012

Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems.

Annu Rev Biophys 2010 ;39:515-37

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94158-2517, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.biophys.050
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http://dx.doi.org/10.1146/annurev.biophys.050708.133652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965450PMC
July 2010

Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics.

Science 2008 Mar;319(5869):1539-43

Department of Cellular and Molecular Pharmacology, University of California at San Francisco, 600 16th Street, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1126/science.1151153DOI Listing
March 2008

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

Science 2006 Feb 19;311(5762):822-6. Epub 2006 Jan 19.

Department of Cellular and Molecular Pharmacology, University of California-San Francisco, 600 16th Street, San Francisco, CA 94143-2240, USA.

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http://dx.doi.org/10.1126/science.1120941DOI Listing
February 2006

The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.

Proc Natl Acad Sci U S A 2002 Jan 2;99(1):78-83. Epub 2002 Jan 2.

Department of Biochemistry and Molecular Biology, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97201-3098, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.012399599
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http://dx.doi.org/10.1073/pnas.012399599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC117517PMC
January 2002