Publications by authors named "Caicun Zhou"

100Publications

Combinational immunotherapy based on immune checkpoints inhibitors in small cell lung cancer: is this the beginning to reverse the refractory situation?

J Thorac Dis 2020 Oct;12(10):6070-6089

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/jtd-20-1689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656422PMC
October 2020

Mutational landscape and evolutionary pattern of liver and brain metastasis in lung adenocarcinoma.

J Thorac Oncol 2020 Nov 11. Epub 2020 Nov 11.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.10.128DOI Listing
November 2020

The cutting-edge progress of immune-checkpoint blockade in lung cancer.

Cell Mol Immunol 2020 Nov 11. Epub 2020 Nov 11.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/s41423-020-00577-5DOI Listing
November 2020

Lung cancer in China: current and prospect.

Curr Opin Oncol 2020 Nov 5. Epub 2020 Nov 5.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1097/CCO.0000000000000703DOI Listing
November 2020

Galectin-9-based immune risk score model helps to predict relapse in stage I-III small cell lung cancer.

J Immunother Cancer 2020 Oct;8(2)

Department of Medical Oncology, Shanghai Pulmonary Hospital,Tongji University Medical School Cancer Institute, Tongji University School of Medicine, No 507 Zhengmin Road, Shanghai 200433, China

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http://dx.doi.org/10.1136/jitc-2020-001391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577067PMC
October 2020

Association of baseline peripheral-blood eosinophil count with immune checkpoint inhibitor-related pneumonitis and clinical outcomes in patients with non-small cell lung cancer receiving immune checkpoint inhibitors.

Lung Cancer 2020 Aug 23;150:76-82. Epub 2020 Aug 23.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.08.015DOI Listing
August 2020

Soluble PD-L1 as a Predictor of the Response to EGFR-TKIs in Non-small Cell Lung Cancer Patients With Mutations.

Front Oncol 2020 25;10:1455. Epub 2020 Aug 25.

Department of Medical Oncology, Shanghai Pulmonary Hospital and Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.3389/fonc.2020.01455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477347PMC
August 2020

Targeting ferroptosis for cancer therapy: exploring novel strategies from its mechanisms and role in cancers.

Transl Lung Cancer Res 2020 Aug;9(4):1569-1584

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/tlcr-20-341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481593PMC
August 2020

CD39: the potential target in small cell lung cancer.

Transl Lung Cancer Res 2020 Aug;9(4):1483-1495

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/tlcr-20-798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481638PMC
August 2020

Impact of ALK variants on brain metastasis and treatment response in advanced NSCLC patients with oncogenic ALK fusion.

Transl Lung Cancer Res 2020 Aug;9(4):1452-1463

Division of Hematology, Oncology and Blood & Marrow Transplantation, Department of Internal Medicine, Holden Comprehensive Cancer Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA.

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http://dx.doi.org/10.21037/tlcr-19-346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481619PMC
August 2020

The impact of exon 19 deletion subtypes on clinical outcomes in non-small cell lung cancer.

Transl Lung Cancer Res 2020 Aug;9(4):1149-1158

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University, Shanghai, China.

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http://dx.doi.org/10.21037/tlcr-19-359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481579PMC
August 2020

Predictive and prognostic significance of M descriptors of the 8th TNM classification for advanced NSCLC patients treated with immune checkpoint inhibitors.

Transl Lung Cancer Res 2020 Aug;9(4):1053-1066

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/tlcr-19-396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481592PMC
August 2020

Refined Stratification Based on Baseline Concomitant Mutations and Longitudinal circulating tumor DNA Monitoring in Advanced EGFR-mutant Lung Adenocarcinoma under Gefitinib Treatment.

J Thorac Oncol 2020 Sep 8. Epub 2020 Sep 8.

State Key Laboratory of Molecular Oncology, Department of Medical Oncology, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.08.020DOI Listing
September 2020

Immune-checkpoint inhibitors plus chemotherapy versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer.

J Immunother Cancer 2020 Sep;8(2)

Department of Medical Oncology, Shanghai Pulmonary Hospital, Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China

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http://dx.doi.org/10.1136/jitc-2020-001300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477983PMC
September 2020

Treatment Algorithm for Advanced ALK-Rearranged NSCLC: Reply.

J Thorac Oncol 2020 Sep;15(9):e157-e158

Department of Medical Oncology, Shanghai Pulmonary Hospital, Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.06.005DOI Listing
September 2020

Hypoproteinemia being a manifestation of immunotherapy-related liver dysfunction.

Ann Transl Med 2020 Jul;8(14):889

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/atm-20-4980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396795PMC
July 2020

The efficacy and complications of computed tomography guided microwave ablation in lung cancer.

Ann Palliat Med 2020 Sep 30;9(5):2760-2765. Epub 2020 Jul 30.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/apm-20-255DOI Listing
September 2020

Expression of PD-1 and PD-L1 on Tumor-Infiltrating Lymphocytes Predicts Prognosis in Patients with Small-Cell Lung Cancer.

Onco Targets Ther 2020 3;13:6475-6483. Epub 2020 Jul 3.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S252031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342461PMC
July 2020

Afatinib in patients with advanced non-small cell lung cancer harboring HER2 mutations, previously treated with chemotherapy: A phase II trial.

Lung Cancer 2020 09 16;147:209-213. Epub 2020 Jul 16.

Medical Oncology, Shanghai Pulmonary Hospital, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.07.017DOI Listing
September 2020

HOTAIR induces EGFR-TKIs resistance in non-small cell lung cancer through epithelial-mesenchymal transition.

Lung Cancer 2020 09 2;147:99-105. Epub 2020 Jul 2.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University, Tongji University Medical School Cancer Institute, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.06.037DOI Listing
September 2020

Mechanisms of drugs-resistance in small cell lung cancer: DNA-related, RNA-related, apoptosis-related, drug accumulation and metabolism procedure.

Transl Lung Cancer Res 2020 Jun;9(3):768-786

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.21037/tlcr-19-547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354133PMC
June 2020

cGAS-STING, an important pathway in cancer immunotherapy.

J Hematol Oncol 2020 06 22;13(1):81. Epub 2020 Jun 22.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, No 507 Zhengmin Road, Shanghai, 200433, People's Republic of China.

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http://dx.doi.org/10.1186/s13045-020-00916-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310007PMC
June 2020

Pan-cancer analysis identifies TERT alterations as predictive biomarkers for immune checkpoint inhibitors treatment.

Clin Transl Med 2020 Jun 20. Epub 2020 Jun 20.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1002/ctm2.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403829PMC
June 2020

Multi-cancer blood testing combined with PET-CT: road for hope to screen for cancer and guide intervention.

Signal Transduct Target Ther 2020 Jun 12;5(1):95. Epub 2020 Jun 12.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/s41392-020-0210-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293291PMC
June 2020

Association of CD8 T cell apoptosis and EGFR mutation in non-small lung cancer patients.

Thorac Cancer 2020 Aug 4;11(8):2130-2136. Epub 2020 Jun 4.

Department of Medical Oncology, Tongji University Affiliated Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/1759-7714.13504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396381PMC
August 2020

Immunotherapy as a treatment for small cell lung cancer: a case report and brief review.

Transl Lung Cancer Res 2020 Apr;9(2):393-400

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2020.03.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225158PMC
April 2020

Anti PD-1 monoclonal antibody induced autoimmune diabetes mellitus: a case report and brief review.

Transl Lung Cancer Res 2020 Apr;9(2):379-388

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2020.03.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225154PMC
April 2020

Challenges and countermeasures of thoracic oncology in the epidemic of COVID-19.

Transl Lung Cancer Res 2020 Apr;9(2):337-347

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2020.02.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225133PMC
April 2020

Heterogeneity of neoantigen landscape between primary lesions and their matched metastases in lung cancer.

Transl Lung Cancer Res 2020 Apr;9(2):246-256

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2020.03.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225166PMC
April 2020

Killer immunoglobulin-like receptors/human leukocyte antigen class-I, a crucial immune pathway in cancer.

Ann Transl Med 2020 Mar;8(5):244

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/atm.2020.01.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154421PMC
March 2020

Treatment Algorithm for Advanced ALK-Rearranged NSCLC: A Marathon Rather Than a Sprint.

J Thorac Oncol 2020 04;15(4):485-488

Department of Medical Oncology, Shanghai Pulmonary Hospital, Thoracic Cancer Institute, School of Medicine, Tongji University, Shanghai, P. R. China. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.12.130DOI Listing
April 2020

Pan-cancer analysis of mutations as biomarkers for immunotherapy outcomes.

Ann Transl Med 2020 Feb;8(4):141

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/atm.2019.11.52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048975PMC
February 2020

CD137, an attractive candidate for the immunotherapy of lung cancer.

Cancer Sci 2020 May 3;111(5):1461-1467. Epub 2020 Apr 3.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/cas.14354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226203PMC
May 2020

Combination immune checkpoint inhibitors with platinum-based chemotherapy in advanced non-small cell lung cancer: what's known and what's next.

Transl Lung Cancer Res 2019 Dec;8(Suppl 4):S447-S450

Department of Pulmonary Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.21037/tlcr.2019.11.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987347PMC
December 2019

Toxicity of tumor immune checkpoint inhibitors-more attention should be paid.

Transl Lung Cancer Res 2019 Dec;8(6):1125-1133

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.11.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976385PMC
December 2019

Analysis of the association between prior chemotherapy regimens and outcomes of subsequent anti-PD-(L)1 monotherapy in advanced non-small cell lung cancer.

Transl Lung Cancer Res 2019 Dec;8(6):920-928

Department of Medical Oncology, Shanghai Pulmonary Hospital &Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.11.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976343PMC
December 2019

T cell immunoglobulin and mucin-domain containing-3 in non-small cell lung cancer.

Transl Lung Cancer Res 2019 Dec;8(6):895-906

Department of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.11.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976352PMC
December 2019

Characterization of PD-L1 protein expression and CD8 tumor-infiltrating lymphocyte density, and their associations with clinical outcome in small-cell lung cancer.

Transl Lung Cancer Res 2019 Dec;8(6):748-759

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.10.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976348PMC
December 2019

Pan-cancer analysis of Alterations as Biomarkers for Immunotherapy Outcomes.

J Cancer 2020 1;11(4):776-780. Epub 2020 Jan 1.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.7150/jca.41296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959029PMC
January 2020

Cell Block as a Surrogate for Programmed Death-Ligand 1 Staining Testing in Patients of Non-Small Cell Lung Cancer.

J Cancer 2020 1;11(3):551-558. Epub 2020 Jan 1.

Department of Medicine, Division of Medical Oncology, University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.7150/jca.35810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959032PMC
January 2020

Third-Generation TKI Resistance Due to SCLC Transformation: A Case Report and Brief Review.

Onco Targets Ther 2019 19;12:11305-11311. Epub 2019 Dec 19.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S228301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927588PMC
December 2019

Exosomes transmit T790M mutation-induced resistance in EGFR-mutant NSCLC by activating PI3K/AKT signalling pathway.

J Cell Mol Med 2020 01 2;24(2):1529-1540. Epub 2020 Jan 2.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/jcmm.14838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991626PMC
January 2020

Treatment of spine metastases in cancer: a review.

J Int Med Res 2020 Apr 26;48(4):300060519888107. Epub 2019 Dec 26.

Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.1177/0300060519888107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607531PMC
April 2020

Tyrosine kinase inhibitors interstitial pneumonitis: diagnosis and management.

Authors:
Yayi He Caicun Zhou

Transl Lung Cancer Res 2019 Nov;8(Suppl 3):S318-S320

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.05.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894986PMC
November 2019

Uncommon EGFR mutations associate with lower incidence of T790M mutation after EGFR-TKI treatment in patients with advanced NSCLC.

Lung Cancer 2020 01 24;139:133-139. Epub 2019 Nov 24.

Department of Medical Oncology, Shanghai Pulmonary Hospital &Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.11.018DOI Listing
January 2020

Overall Survival with Osimertinib in Untreated, -Mutated Advanced NSCLC.

N Engl J Med 2020 01 21;382(1):41-50. Epub 2019 Nov 21.

From Winship Cancer Institute, Emory University School of Medicine, Atlanta (S.S.R.); the Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospital KU Leuven, Leuven, Belgium (J.V.); the Thoracic Unit, Department of Medical Oncology, Institut Gustave Roussy, Villejuif (D.P., J.-C.S.), and University Paris Sud, Orsay (J.-C.S.) - both in France; the Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (B.C.C.), and the Division of Medical Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheong-ju (K.H.L.) - both in South Korea; the Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (J.E.G.); the Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo (Y.O.), the Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka (F.I.), and the Department of Thoracic Oncology, Kansai Medical University Hospital, Osaka (T.K.) - all in Japan; Pulmonary Hospital of Tongji University, Shanghai (C.Z.), and Jilin Provincial Cancer Hospital, Changchun (Y.C.) - both in China; the Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok (T.R.), and the Oncology Unit, Department of Medicine, Chiang Mai University, Chiang Mai (B.C.) - both in Thailand; Kent Oncology Centre, Maidstone Hospital, and Tunbridge Wells NHS Trust, Maidstone (R.S.), and Late Oncology Statistics (A.T., R.H.) and Oncology Research and Development (M.S., Y.R.), AstraZeneca, Cambridge - both in the United Kingdom; Hospital Regional Universitario Málaga, Instituto de Investigación Biomédica de Málaga, Malaga, Spain (M.C.); William Osler Health System, University of Toronto, Toronto (P.C.); the Department of Medicine and Surgery, University of Parma and Medical Oncology Unit, University Hospital of Parma, Parma, Italy (M.T.); the Department of Medical Oncology, Austin Health, Melbourne, VIC, Australia (T.J.); the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan (M.-C.L.); and Early Oncology Research and Development, AstraZeneca, Gaithersburg, MD (J.-C.S.).

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http://dx.doi.org/10.1056/NEJMoa1913662DOI Listing
January 2020

Does selected immunological panel possess the value of predicting the prognosis of early-stage resectable non-small cell lung cancer?

Transl Lung Cancer Res 2019 Oct;8(5):559-574

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.09.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835112PMC
October 2019

Response to the combination of dabrafenib, trametinib and osimertinib in a patient with EGFR-mutant NSCLC harboring an acquired BRAF mutation.

Lung Cancer 2020 01 14;139:219-220. Epub 2019 Oct 14.

Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1016/j.lungcan.2019.10.014DOI Listing
January 2020

EGFR-TKIs plus bevacizumab demonstrated survival benefit than EGFR-TKIs alone in patients with EGFR-mutant NSCLC and multiple brain metastases.

Eur J Cancer 2019 11 27;121:98-108. Epub 2019 Sep 27.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China; Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.08.021DOI Listing
November 2019

OX40 (CD134) and OX40 ligand, important immune checkpoints in cancer.

Onco Targets Ther 2019 6;12:7347-7353. Epub 2019 Sep 6.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S214211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735535PMC
September 2019

Major histocompatibility complex class II molecule in non-small cell lung cancer diagnosis, prognosis and treatment.

Onco Targets Ther 2019 5;12:7281-7288. Epub 2019 Sep 5.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S214231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733341PMC
September 2019

Impact of EGFR-TKIs combined with PD-L1 antibody on the lung tissue of EGFR-driven tumor-bearing mice.

Lung Cancer 2019 11 19;137:85-93. Epub 2019 Sep 19.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.09.016DOI Listing
November 2019

OX40 and OX40L protein expression of tumor infiltrating lymphocytes in non-small cell lung cancer and its role in clinical outcome and relationships with other immune biomarkers.

Transl Lung Cancer Res 2019 Aug;8(4):352-366

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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http://dx.doi.org/10.21037/tlcr.2019.08.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749115PMC
August 2019

Tumor neoantigens: from basic research to clinical applications.

J Hematol Oncol 2019 09 6;12(1):93. Epub 2019 Sep 6.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, No. 507, Zheng Min Road, Shanghai, 200433, China.

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http://dx.doi.org/10.1186/s13045-019-0787-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731555PMC
September 2019

Galectin-9 in non-small cell lung cancer.

Lung Cancer 2019 10 16;136:80-85. Epub 2019 Aug 16.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, No. 507 Zhengmin Road, Shanghai, 200433, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.08.014DOI Listing
October 2019

Association Between Nicotine-dependent Gene Polymorphism and Smoking Cessation in Patients With Lung Cancer.

Clin Lung Cancer 2020 03 17;21(2):171-176. Epub 2019 Jul 17.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2019.07.002DOI Listing
March 2020

Genomic landscape and its correlations with tumor mutational burden, PD-L1 expression, and immune cells infiltration in Chinese lung squamous cell carcinoma.

J Hematol Oncol 2019 07 12;12(1):75. Epub 2019 Jul 12.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Zheng Min Road, Shanghai, 200433, China.

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http://dx.doi.org/10.1186/s13045-019-0762-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625041PMC
July 2019

Value of heart rate recovery in female patients with pulmonary arterial hypertension due to systemic lupus erythematosus.

Clin Respir J 2019 Sep 27;13(9):545-554. Epub 2019 Aug 27.

Department of Pulmonary Function Test, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/crj.13056DOI Listing
September 2019

Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.

Cell Rep 2019 07;28(2):512-525.e6

State Key Laboratory of Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; CAS Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China; School of Life Science and Technology, Shanghai Tech University, Shanghai 200120, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.026DOI Listing
July 2019

High feasibility of cytological specimens for detection of fusion by reverse transcriptase PCR in Chinese patients with advanced non-small-cell lung cancer.

Onco Targets Ther 2019 1;12:3305-3311. Epub 2019 May 1.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, People's Republic of China,

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http://dx.doi.org/10.2147/OTT.S198827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501702PMC
May 2019

Clinical features and therapeutic options in non-small cell lung cancer patients with concomitant mutations of EGFR, ALK, ROS1, KRAS or BRAF.

Cancer Med 2019 06 24;8(6):2858-2866. Epub 2019 Apr 24.

Department of Lung Cancer and Immunology, Shanghai Pulmonary Hospital, Tongji University, Shanghai, China.

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http://dx.doi.org/10.1002/cam4.2183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558647PMC
June 2019

Alectinib versus crizotinib in untreated Asian patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer (ALESIA): a randomised phase 3 study.

Lancet Respir Med 2019 05 10;7(5):437-446. Epub 2019 Apr 10.

Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(19)30053-0DOI Listing
May 2019

Re-biopsy and liquid biopsy for patients with non-small cell lung cancer after EGFR-tyrosine kinase inhibitor failure.

Thorac Cancer 2019 04 18;10(4):957-965. Epub 2019 Mar 18.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1759-7714.13
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http://dx.doi.org/10.1111/1759-7714.13035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449239PMC
April 2019

Clinical value of neutrophil-to-lymphocyte ratio in patients with non-small-cell lung cancer treated with PD-1/PD-L1 inhibitors.

Lung Cancer 2019 04 10;130:76-83. Epub 2019 Feb 10.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.02.009DOI Listing
April 2019

Antibiotics are associated with attenuated efficacy of anti-PD-1/PD-L1 therapies in Chinese patients with advanced non-small cell lung cancer.

Lung Cancer 2019 04 31;130:10-17. Epub 2019 Jan 31.

Department of Medical Oncology, Shanghai Pulmonary Hospital &Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.01.017DOI Listing
April 2019

Protective effects of hesperetin on lipopolysaccharide-induced acute lung injury by targeting MD2.

Eur J Pharmacol 2019 Jun 23;852:151-158. Epub 2019 Feb 23.

Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2019.02.042DOI Listing
June 2019

EGFR-targeted therapy alters the tumor microenvironment in EGFR-driven lung tumors: Implications for combination therapies.

Int J Cancer 2019 09 19;145(5):1432-1444. Epub 2019 Feb 19.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1002/ijc.32191DOI Listing
September 2019

PD-L1 expression and its effect on clinical outcomes of EGFR-mutant NSCLC patients treated with EGFR-TKIs.

Cancer Biol Med 2018 Nov;15(4):434-442

Department of General and Oncological Pulmonology, University Clinical Hospital Norbert Barlicki, Medical University of Lodz, Lodz 50243, Poland.

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http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372913PMC
November 2018

Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.

Cancer Immunol Res 2019 04 12;7(4):630-643. Epub 2019 Feb 12.

Department of Medicine, Division of Medical Oncology and Department of Pathology, University of Colorado Cancer Center, Aurora, Colorado.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0640DOI Listing
April 2019

First-line continual EGFR-TKI plus local ablative therapy demonstrated survival benefit in EGFR-mutant NSCLC patients with oligoprogressive disease.

J Cancer 2019 1;10(2):522-529. Epub 2019 Jan 1.

Department of Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.7150/jca.26494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360299PMC
January 2019

Loss of T790M mutation is associated with early progression to osimertinib in Chinese patients with advanced NSCLC who are harboring EGFR T790M.

Lung Cancer 2019 02 12;128:33-39. Epub 2018 Dec 12.

Department of Medical Oncology, Shanghai Pulmonary Hospital &Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183069
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http://dx.doi.org/10.1016/j.lungcan.2018.12.010DOI Listing
February 2019

Arbutin attenuates LPS-induced lung injury via Sirt1/ Nrf2/ NF-κBp65 pathway.

Pulm Pharmacol Ther 2019 02 6;54:53-59. Epub 2018 Dec 6.

The Third Affiliated Hospital of Soochow University, Changzhou, 213000, China; Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China. Electronic address:

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http://dx.doi.org/10.1016/j.pupt.2018.12.001DOI Listing
February 2019

Dual integrin αvβ 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging.

Nanoscale Res Lett 2018 Nov 27;13(1):380. Epub 2018 Nov 27.

Department of Medical Oncology, Shanghai Pulmonary Hospital and Thoracic Cancer Institute, Tongji University School of Medicine, No. 507, Zheng Min Road, Shanghai, 200433, People's Republic of China.

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http://dx.doi.org/10.1186/s11671-018-2797-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258593PMC
November 2018

Impact of serum vascular endothelial growth factor and interleukin-6 on treatment response to epidermal growth factor receptor tyrosine kinase inhibitors in patients with non-small-cell lung cancer.

Lung Cancer 2018 11 31;125:22-28. Epub 2018 Aug 31.

Department of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.08.025DOI Listing
November 2018

TIM-3, a promising target for cancer immunotherapy.

Onco Targets Ther 2018 16;11:7005-7009. Epub 2018 Oct 16.

Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

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https://www.dovepress.com/tim-3-a-promising-target-for-cance
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http://dx.doi.org/10.2147/OTT.S170385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198883PMC
October 2018