Christi Asperen

Christi Asperen

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Christi Asperen

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Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers.

Authors:
Frank Qian Matti A Rookus Goska Leslie Harvey A Risch Mark H Greene Cora M Aalfs Muriel A Adank Julian Adlard Bjarni A Agnarsson Munaza Ahmed Kristiina Aittomäki Irene L Andrulis Norbert Arnold Banu K Arun Margreet G E M Ausems Jacopo Azzollini Daniel Barrowdale Julian Barwell Javier Benitez Katarzyna Białkowska Valérie Bonadona Julika Borde Ake Borg Angela R Bradbury Joan Brunet Saundra S Buys Trinidad Caldés Maria A Caligo Ian Campbell Jonathan Carter Jocelyne Chiquette Wendy K Chung Kathleen B M Claes J Margriet Collée Marie-Agnès Collonge-Rame Fergus J Couch Mary B Daly Capucine Delnatte Orland Diez Susan M Domchek Cecilia M Dorfling Jacqueline Eason Douglas F Easton Ros Eeles Christoph Engel D Gareth Evans Laurence Faivre Lidia Feliubadaló Lenka Foretova Eitan Friedman Debra Frost Patricia A Ganz Judy Garber Vanesa Garcia-Barberan Andrea Gehrig Gord Glendon Andrew K Godwin Encarna B Gómez Garcia Ute Hamann Jan Hauke John L Hopper Peter J Hulick Evgeny N Imyanitov Claudine Isaacs Louise Izatt Anna Jakubowska Ramunas Janavicius Esther M John Beth Y Karlan Carolien M Kets Yael Laitman Conxi Lázaro Dominique Leroux Jenny Lester Fabienne Lesueur Jennifer T Loud Jan Lubiński Alicja Łukomska Lesley McGuffog Noura Mebirouk Hanne E J Meijers-Heijboer Alfons Meindl Austin Miller Marco Montagna Thea M Mooij Emmanuelle Mouret-Fourme Katherine L Nathanson Bita Nehoray Susan L Neuhausen Heli Nevanlinna Finn C Nielsen Kenneth Offit Edith Olah Kai-Ren Ong Jan C Oosterwijk Laura Ottini Michael T Parsons Paolo Peterlongo Georg Pfeiler Nisha Pradhan Paolo Radice Susan J Ramus Johanna Rantala Gad Rennert Mark Robson Gustavo C Rodriguez Ritu Salani Maren T Scheuner Rita K Schmutzler Payal D Shah Lucy E Side Jacques Simard Christian F Singer Doris Steinemann Dominique Stoppa-Lyonnet Yen Yen Tan Manuel R Teixeira Mary Beth Terry Mads Thomassen Marc Tischkowitz Silvia Tognazzo Amanda E Toland Nadine Tung Christi J van Asperen Klaartje van Engelen Elizabeth J van Rensburg Laurence Venat-Bouvet Jeroen Vierstraete Gabriel Wagner Lisa Walker Jeffrey N Weitzel Drakoulis Yannoukakos Antonis C Antoniou David E Goldgar Olufunmilayo I Olopade Georgia Chenevix-Trench Timothy R Rebbeck Dezheng Huo

Br J Cancer 2019 Jul 19;121(2):180-192. Epub 2019 Jun 19.

Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41416-019-0492-8DOI Listing
July 2019

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.

Authors:
Michael T Parsons Emma Tudini Hongyan Li Eric Hahnen Barbara Wappenschmidt Lidia Feliubadaló Cora M Aalfs Simona Agata Kristiina Aittomäki Elisa Alducci María Concepción Alonso-Cerezo Norbert Arnold Bernd Auber Rachel Austin Jacopo Azzollini Judith Balmaña Elena Barbieri Claus R Bartram Ana Blanco Britta Blümcke Sandra Bonache Bernardo Bonanni Åke Borg Beatrice Bortesi Joan Brunet Carla Bruzzone Karolin Bucksch Giulia Cagnoli Trinidad Caldés Almuth Caliebe Maria A Caligo Mariarosaria Calvello Gabriele L Capone Sandrine M Caputo Ileana Carnevali Estela Carrasco Virginie Caux-Moncoutier Pietro Cavalli Giulia Cini Edward M Clarke Paola Concolino Elisa J Cops Laura Cortesi Fergus J Couch Esther Darder Miguel de la Hoya Michael Dean Irmgard Debatin Jesús Del Valle Capucine Delnatte Nicolas Derive Orland Diez Nina Ditsch Susan M Domchek Véronique Dutrannoy Diana M Eccles Hans Ehrencrona Ute Enders D Gareth Evans Ulrike Faust Ute Felbor Irene Feroce Miriam Fine Henrique C R Galvao Gaetana Gambino Andrea Gehrig Francesca Gensini Anne-Marie Gerdes Aldo Germani Jutta Giesecke Viviana Gismondi Carolina Gómez Encarna B Gómez Garcia Sara González Elia Grau Sabine Grill Eva Gross Aliana Guerrieri-Gonzaga Marine Guillaud-Bataille Sara Gutiérrez-Enríquez Thomas Haaf Karl Hackmann Thomas V O Hansen Marion Harris Jan Hauke Tilman Heinrich Heide Hellebrand Karen N Herold Ellen Honisch Judit Horvath Claude Houdayer Verena Hübbel Silvia Iglesias Angel Izquierdo Paul A James Linda A M Janssen Udo Jeschke Silke Kaulfuß Katharina Keupp Marion Kiechle Alexandra Kölbl Sophie Krieger Torben A Kruse Anders Kvist Fiona Lalloo Mirjam Larsen Vanessa L Lattimore Charlotte Lautrup Susanne Ledig Elena Leinert Alexandra L Lewis Joanna Lim Markus Loeffler Adrià López-Fernández Emanuela Lucci-Cordisco Nicolai Maass Siranoush Manoukian Monica Marabelli Laura Matricardi Alfons Meindl Rodrigo D Michelli Setareh Moghadasi Alejandro Moles-Fernández Marco Montagna Gemma Montalban Alvaro N Monteiro Eva Montes Luigi Mori Lidia Moserle Clemens R Müller Christoph Mundhenke Nadia Naldi Katherine L Nathanson Matilde Navarro Heli Nevanlinna Cassandra B Nichols Dieter Niederacher Henriette R Nielsen Kai-Ren Ong Nicholas Pachter Edenir I Palmero Laura Papi Inge Sokilde Pedersen Bernard Peissel Pedro Pérez-Segura Katharina Pfeifer Marta Pineda Esther Pohl-Rescigno Nicola K Poplawski Berardino Porfirio Anne S Quante Juliane Ramser Rui M Reis Françoise Revillion Kerstin Rhiem Barbara Riboli Julia Ritter Daniela Rivera Paula Rofes Andreas Rump Monica Salinas Ana María Sánchez de Abajo Gunnar Schmidt Ulrike Schoenwiese Jochen Seggewiß Ares Solanes Doris Steinemann Mathias Stiller Dominique Stoppa-Lyonnet Kelly J Sullivan Rachel Susman Christian Sutter Sean V Tavtigian Soo H Teo Alex Teulé Mads Thomassen Maria Grazia Tibiletti Silvia Tognazzo Amanda E Toland Eva Tornero Therese Törngren Sara Torres-Esquius Angela Toss Alison H Trainer Christi J van Asperen Marion T van Mackelenbergh Liliana Varesco Gardenia Vargas-Parra Raymonda Varon Ana Vega Ángela Velasco Anne-Sophie Vesper Alessandra Viel Maaike P G Vreeswijk Sebastian A Wagner Anke Waha Logan C Walker Rhiannon J Walters Shan Wang-Gohrke Bernhard H F Weber Wilko Weichert Kerstin Wieland Lisa Wiesmüller Isabell Witzel Achim Wöckel Emma R Woodward Silke Zachariae Valentina Zampiga Christine Zeder-Göß Conxi Lázaro Arcangela De Nicolo Paolo Radice Christoph Engel Rita K Schmutzler David E Goldgar Amanda B Spurdle

Hum Mutat 2019 May 27. Epub 2019 May 27.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/humu.23818DOI Listing
May 2019

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study.

Authors:
Frank Qian Shengfeng Wang Jonathan Mitchell Lesley McGuffog Daniel Barrowdale Goska Leslie Jan C Oosterwijk Wendy K Chung D Gareth Evans Christoph Engel Karin Kast Cora M Aalfs Muriel A Adank Julian Adlard Bjarni A Agnarsson Kristiina Aittomäki Elisa Alducci Irene L Andrulis Banu K Arun Margreet G E M Ausems Jacopo Azzollini Emmanuelle Barouk-Simonet Julian Barwell Muriel Belotti Javier Benitez Andreas Berger Ake Borg Angela R Bradbury Joan Brunet Saundra S Buys Trinidad Caldes Maria A Caligo Ian Campbell Sandrine M Caputo Jocelyne Chiquette Kathleen B M Claes J Margriet Collée Fergus J Couch Isabelle Coupier Mary B Daly Rosemarie Davidson Orland Diez Susan M Domchek Alan Donaldson Cecilia M Dorfling Ros Eeles Lidia Feliubadaló Lenka Foretova Jeffrey Fowler Eitan Friedman Debra Frost Patricia A Ganz Judy Garber Vanesa Garcia-Barberan Gord Glendon Andrew K Godwin Encarna B Gómez Garcia Jacek Gronwald Eric Hahnen Ute Hamann Alex Henderson Carolyn B Hendricks John L Hopper Peter J Hulick Evgeny N Imyanitov Claudine Isaacs Louise Izatt Ángel Izquierdo Anna Jakubowska Katarzyna Kaczmarek Eunyoung Kang Beth Y Karlan Carolien M Kets Sung-Won Kim Zisun Kim Ava Kwong Yael Laitman Christine Lasset Min Hyuk Lee Jong Won Lee Jihyoun Lee Jenny Lester Fabienne Lesueur Jennifer T Loud Jan Lubinski Noura Mebirouk Hanne E J Meijers-Heijboer Alfons Meindl Austin Miller Marco Montagna Thea M Mooij Patrick J Morrison Emmanuelle Mouret-Fourme Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Dieter Niederacher Finn C Nielsen Robert L Nussbaum Kenneth Offit Edith Olah Kai-Ren Ong Laura Ottini Sue K Park Paolo Peterlongo Georg Pfeiler Catherine M Phelan Bruce Poppe Nisha Pradhan Paolo Radice Susan J Ramus Johanna Rantala Mark Robson Gustavo C Rodriguez Rita K Schmutzler Christina G Hutten Selkirk Payal D Shah Jacques Simard Christian F Singer Johanna Sokolowska Dominique Stoppa-Lyonnet Christian Sutter Yen Yen Tan R Manuel Teixeira Soo H Teo Mary Beth Terry Mads Thomassen Marc Tischkowitz Amanda E Toland Katherine M Tucker Nadine Tung Christi J van Asperen Klaartje van Engelen Elizabeth J van Rensburg Shan Wang-Gohrke Barbara Wappenschmidt Jeffrey N Weitzel Drakoulis Yannoukakos Mark H Greene Matti A Rookus Douglas F Easton Georgia Chenevix-Trench Antonis C Antoniou David E Goldgar Olufunmilayo I Olopade Timothy R Rebbeck Dezheng Huo

J Natl Cancer Inst 2019 Apr;111(4):350-364

Department of Medicine, The University of Chicago, Chicago, IL.

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https://academic.oup.com/jnci/advance-article/doi/10.1093/jn
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http://dx.doi.org/10.1093/jnci/djy132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449171PMC
April 2019

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.

Authors:
Manuel A Ferreira Eric R Gamazon Fares Al-Ejeh Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Adalgeir Arason Volker Arndt Kristan J Aronson Banu K Arun Ella Asseryanis Jacopo Azzollini Judith Balmaña Daniel R Barnes Daniel Barrowdale Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Katarzyna Białkowska Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Ake Borg Hiltrud Brauch Hermann Brenner Annegien Broeks Barbara Burwinkel Trinidad Caldés Maria A Caligo Daniele Campa Ian Campbell Federico Canzian Jonathan Carter Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Hans Christiansen Wendy K Chung Kathleen B M Claes Christine L Clarke Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Miguel de la Hoya Joe Dennis Peter Devilee Orland Diez Thilo Dörk Alison M Dunning Miriam Dwek Diana M Eccles Bent Ejlertsen Carolina Ellberg Christoph Engel Mikael Eriksson Peter A Fasching Olivia Fletcher Henrik Flyger Eitan Friedman Debra Frost Marike Gabrielson Manuela Gago-Dominguez Patricia A Ganz Susan M Gapstur Judy Garber Montserrat García-Closas José A García-Sáenz Mia M Gaudet Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Mark H Greene Jacek Gronwald Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Wei He Jane Heyworth Frans B L Hogervorst Antoinette Hollestelle Robert N Hoover John L Hopper Peter J Hulick Keith Humphreys Evgeny N Imyanitov Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul A James Ramunas Janavicius Rachel C Jankowitz Esther M John Nichola Johnson Vijai Joseph Beth Y Karlan Elza Khusnutdinova Johanna I Kiiski Yon-Dschun Ko Michael E Jones Irene Konstantopoulou Vessela N Kristensen Yael Laitman Diether Lambrechts Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Sara Lindström Jirong Long Jennifer T Loud Jan Lubiński Enes Makalic Arto Mannermaa Mehdi Manoochehri Sara Margolin Tabea Maurer Dimitrios Mavroudis Lesley McGuffog Alfons Meindl Usha Menon Kyriaki Michailidou Austin Miller Marco Montagna Fernando Moreno Lidia Moserle Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Finn C Nielsen Liene Nikitina-Zake Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Håkan Olsson Ana Osorio Janos Papp Tjoung-Won Park-Simon Michael T Parsons Inge Sokilde Pedersen Ana Peixoto Paolo Peterlongo Paul D P Pharoah Dijana Plaseska-Karanfilska Bruce Poppe Nadege Presneau Paolo Radice Johanna Rantala Gad Rennert Harvey A Risch Emmanouil Saloustros Kristin Sanden Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F Singer Penny Soucy Melissa C Southey John J Spinelli Amanda B Spurdle Jennifer Stone Anthony J Swerdlow William J Tapper Jack A Taylor Manuel R Teixeira Mary Beth Terry Alex Teulé Mads Thomassen Kathrin Thöne Darcy L Thull Marc Tischkowitz Amanda E Toland Diana Torres Thérèse Truong Nadine Tung Celine M Vachon Christi J van Asperen Ans M W van den Ouweland Elizabeth J van Rensburg Ana Vega Alessandra Viel Qin Wang Barbara Wappenschmidt Jeffrey N Weitzel Camilla Wendt Robert Winqvist Xiaohong R Yang Drakoulis Yannoukakos Argyrios Ziogas Peter Kraft Antonis C Antoniou Wei Zheng Douglas F Easton Roger L Milne Jonathan Beesley Georgia Chenevix-Trench

Nat Commun 2019 04 15;10(1):1741. Epub 2019 Apr 15.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.

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http://dx.doi.org/10.1038/s41467-018-08053-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465407PMC
April 2019

Genome-wide association study of germline variants and breast cancer-specific mortality.

Authors:
Maria Escala-Garcia Qi Guo Thilo Dörk Sander Canisius Renske Keeman Joe Dennis Jonathan Beesley Julie Lecarpentier Manjeet K Bolla Qin Wang Jean Abraham Irene L Andrulis Hoda Anton-Culver Volker Arndt Paul L Auer Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Bram Boeckx Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Hermann Brenner Adam Brentnall Louise Brinton Per Broberg Ian W Brock Sara Y Brucker Barbara Burwinkel Carlos Caldas Trinidad Caldés Daniele Campa Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Georgia Chenevix-Trench Ting-Yuan David Cheng Suet-Feung Chin Christine L Clarke Emilie Cordina-Duverger Fergus J Couch David G Cox Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Janet A Dunn Alison M Dunning Lorraine Durcan Miriam Dwek Helena M Earl Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Jonine Figueroa Dieter Flesch-Janys Henrik Flyger Marike Gabrielson Manuela Gago-Dominguez Eva Galle Susan M Gapstur Montserrat García-Closas José A García-Sáenz Mia M Gaudet Angela George Vassilios Georgoulias Graham G Giles Gord Glendon David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Ute Hamann Susan Hankinson Elaine F Harkness Patricia A Harrington Steven N Hart Jaana M Hartikainen Alexander Hein Peter Hillemanns Louise Hiller Bernd Holleczek Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Wolfgang Janni Esther M John Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Cari M Kitahara Julia A Knight Yon-Dschun Ko Linetta B Koppert Veli-Matti Kosma Peter Kraft Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Lian Li Annika Lindblom Sara Lindström Martha Linet Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jan Lubiński Michael P Lux Robert J MacInnis Melanie Maierthaler Tom Maishman Enes Makalic Arto Mannermaa Mehdi Manoochehri Siranoush Manoukian Sara Margolin Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Pooja Middha Nicola Miller Roger L Milne Fernando Moreno Anna Marie Mulligan Claire Mulot Rami Nassir Susan L Neuhausen William T Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Christos Petridis Mila Pinchev Karoliona Prajzendanc Ross Prentice Nadege Presneau Darya Prokofieva Katri Pylkäs Brigitte Rack Paolo Radice Dhanya Ramachandran Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Rebecca Roylance Emmanouil Saloustros Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Lukas Schwentner Rodney J Scott Christopher Scott Caroline Seynaeve Mitul Shah Jacques Simard Ann Smeets Christof Sohn Melissa C Southey Anthony J Swerdlow Aline Talhouk Rulla M Tamimi William J Tapper Manuel R Teixeira Maria Tengström Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Constance Turman Clare Turnbull Hans-Ulrich Ulmer Michael Untch Celine Vachon Christi J van Asperen Ans M W van den Ouweland Elke M van Veen Camilla Wendt Alice S Whittemore Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Yan Zhang Douglas F Easton Peter A Fasching Heli Nevanlinna Diana M Eccles Paul D P Pharoah Marjanka K Schmidt

Br J Cancer 2019 Mar 21;120(6):647-657. Epub 2019 Feb 21.

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Division of Molecular Pathology, Amsterdam, The Netherlands.

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http://www.nature.com/articles/s41416-019-0393-x
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http://dx.doi.org/10.1038/s41416-019-0393-xDOI Listing
March 2019

The functional impact of variants of uncertain significance in BRCA2.

Genet Med 2019 02 10;21(2):293-302. Epub 2018 Jul 10.

Department of Human Genetics, Leiden University Medical Center, PO Box 9600, Leiden, 2300RC, The Netherlands.

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http://dx.doi.org/10.1038/s41436-018-0052-2DOI Listing
February 2019

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.

Authors:
Timothy R Rebbeck Tara M Friebel Eitan Friedman Ute Hamann Dezheng Huo Ava Kwong Edith Olah Olufunmilayo I Olopade Angela R Solano Soo-Hwang Teo Mads Thomassen Jeffrey N Weitzel T L Chan Fergus J Couch David E Goldgar Torben A Kruse Edenir Inêz Palmero Sue Kyung Park Diana Torres Elizabeth J van Rensburg Lesley McGuffog Michael T Parsons Goska Leslie Cora M Aalfs Julio Abugattas Julian Adlard Simona Agata Kristiina Aittomäki Lesley Andrews Irene L Andrulis Adalgeir Arason Norbert Arnold Banu K Arun Ella Asseryanis Leo Auerbach Jacopo Azzollini Judith Balmaña Monica Barile Rosa B Barkardottir Daniel Barrowdale Javier Benitez Andreas Berger Raanan Berger Amie M Blanco Kathleen R Blazer Marinus J Blok Valérie Bonadona Bernardo Bonanni Angela R Bradbury Carole Brewer Bruno Buecher Saundra S Buys Trinidad Caldes Almuth Caliebe Maria A Caligo Ian Campbell Sandrine M Caputo Jocelyne Chiquette Wendy K Chung Kathleen B M Claes J Margriet Collée Jackie Cook Rosemarie Davidson Miguel de la Hoya Kim De Leeneer Antoine de Pauw Capucine Delnatte Orland Diez Yuan Chun Ding Nina Ditsch Susan M Domchek Cecilia M Dorfling Carolina Velazquez Bernd Dworniczak Jacqueline Eason Douglas F Easton Ros Eeles Hans Ehrencrona Bent Ejlertsen Christoph Engel Stefanie Engert D Gareth Evans Laurence Faivre Lidia Feliubadaló Sandra Fert Ferrer Lenka Foretova Jeffrey Fowler Debra Frost Henrique C R Galvão Patricia A Ganz Judy Garber Marion Gauthier-Villars Andrea Gehrig Anne-Marie Gerdes Paul Gesta Giuseppe Giannini Sophie Giraud Gord Glendon Andrew K Godwin Mark H Greene Jacek Gronwald Angelica Gutierrez-Barrera Eric Hahnen Jan Hauke Alex Henderson Julia Hentschel Frans B L Hogervorst Ellen Honisch Evgeny N Imyanitov Claudine Isaacs Louise Izatt Angel Izquierdo Anna Jakubowska Paul James Ramunas Janavicius Uffe Birk Jensen Esther M John Joseph Vijai Katarzyna Kaczmarek Beth Y Karlan Karin Kast KConFab Investigators Sung-Won Kim Irene Konstantopoulou Jacob Korach Yael Laitman Adriana Lasa Christine Lasset Conxi Lázaro Annette Lee Min Hyuk Lee Jenny Lester Fabienne Lesueur Annelie Liljegren Noralane M Lindor Michel Longy Jennifer T Loud Karen H Lu Jan Lubinski Eva Machackova Siranoush Manoukian Véronique Mari Cristina Martínez-Bouzas Zoltan Matrai Noura Mebirouk Hanne E J Meijers-Heijboer Alfons Meindl Arjen R Mensenkamp Ugnius Mickys Austin Miller Marco Montagna Kirsten B Moysich Anna Marie Mulligan Jacob Musinsky Susan L Neuhausen Heli Nevanlinna Joanne Ngeow Huu Phuc Nguyen Dieter Niederacher Henriette Roed Nielsen Finn Cilius Nielsen Robert L Nussbaum Kenneth Offit Anna Öfverholm Kai-Ren Ong Ana Osorio Laura Papi Janos Papp Barbara Pasini Inge Sokilde Pedersen Ana Peixoto Nina Peruga Paolo Peterlongo Esther Pohl Nisha Pradhan Karolina Prajzendanc Fabienne Prieur Pascal Pujol Paolo Radice Susan J Ramus Johanna Rantala Muhammad Usman Rashid Kerstin Rhiem Mark Robson Gustavo C Rodriguez Mark T Rogers Vilius Rudaitis Ane Y Schmidt Rita Katharina Schmutzler Leigha Senter Payal D Shah Priyanka Sharma Lucy E Side Jacques Simard Christian F Singer Anne-Bine Skytte Thomas P Slavin Katie Snape Hagay Sobol Melissa Southey Linda Steele Doris Steinemann Grzegorz Sukiennicki Christian Sutter Csilla I Szabo Yen Y Tan Manuel R Teixeira Mary Beth Terry Alex Teulé Abigail Thomas Darcy L Thull Marc Tischkowitz Silvia Tognazzo Amanda Ewart Toland Sabine Topka Alison H Trainer Nadine Tung Christi J van Asperen Annemieke H van der Hout Lizet E van der Kolk Rob B van der Luijt Mattias Van Heetvelde Liliana Varesco Raymonda Varon-Mateeva Ana Vega Cynthia Villarreal-Garza Anna von Wachenfeldt Lisa Walker Shan Wang-Gohrke Barbara Wappenschmidt Bernhard H F Weber Drakoulis Yannoukakos Sook-Yee Yoon Cristina Zanzottera Jamal Zidan Kristin K Zorn Christina G Hutten Selkirk Peter J Hulick Georgia Chenevix-Trench Amanda B Spurdle Antonis C Antoniou Katherine L Nathanson

Hum Mutat 2018 05 12;39(5):593-620. Epub 2018 Mar 12.

Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.1002/humu.23406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903938PMC
May 2018

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

Authors:
Mara Colombo Irene Lòpez-Perolio Huong D Meeks Laura Caleca Michael T Parsons Hongyan Li Giovanna De Vecchi Emma Tudini Claudia Foglia Patrizia Mondini Siranoush Manoukian Raquel Behar Encarna B Gómez Garcia Alfons Meindl Marco Montagna Dieter Niederacher Ane Y Schmidt Liliana Varesco Barbara Wappenschmidt Manjeet K Bolla Joe Dennis Kyriaki Michailidou Qin Wang Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Alicia Beeghly-Fadel Javier Benitez Bram Boeckx Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Hiltrud Brauch Hermann Brenner Barbara Burwinkel Jenny Chang-Claude Don M Conroy Fergus J Couch Angela Cox Simon S Cross Kamila Czene Peter Devilee Thilo Dörk Mikael Eriksson Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Marike Gabrielson Montserrat García-Closas Graham G Giles Anna González-Neira Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Mikael Hartman Jan Hauke Antoinette Hollestelle John L Hopper Anna Jakubowska Audrey Jung Veli-Matti Kosma Diether Lambrechts Loid Le Marchand Annika Lindblom Jan Lubinski Arto Mannermaa Sara Margolin Hui Miao Roger L Milne Susan L Neuhausen Heli Nevanlinna Janet E Olson Paolo Peterlongo Julian Peto Katri Pylkäs Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Mee Hoong See Melissa C Southey Anthony Swerdlow Soo H Teo Amanda E Toland Ian Tomlinson Thérèse Truong Christi J van Asperen Ans M W van den Ouweland Lizet E van der Kolk Robert Winqvist Drakoulis Yannoukakos Wei Zheng Alison M Dunning Douglas F Easton Alex Henderson Frans B L Hogervorst Louise Izatt Kenneth Offitt Lucy E Side Elizabeth J van Rensburg Study Embrace Study Hebon Lesley McGuffog Antonis C Antoniou Georgia Chenevix-Trench Amanda B Spurdle David E Goldgar Miguel de la Hoya Paolo Radice

Hum Mutat 2018 05 6;39(5):729-741. Epub 2018 Apr 6.

Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT), Milan, Italy.

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http://dx.doi.org/10.1002/humu.23411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947288PMC
May 2018

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Authors:
Maya Ghoussaini Stacey L Edwards Kyriaki Michailidou Silje Nord Richard Cowper-Sal Lari Kinjal Desai Siddhartha Kar Kristine M Hillman Susanne Kaufmann Dylan M Glubb Jonathan Beesley Joe Dennis Manjeet K Bolla Qin Wang Ed Dicks Qi Guo Marjanka K Schmidt Mitul Shah Robert Luben Judith Brown Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Bernard Thienpont Patrick Neven Hans Wildiers Annegien Broeks Laura J Van't Veer Emiel J Th Rutgers Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel Dos-Santos-Silva Lorna Gibson Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Per Hall Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Keitaro Matsuo Hidemi Ito Hiroji Iwata Yasushi Yatabe Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Xiao-Ou Shu Wei Lu Yu-Tang Gao Qiuyin Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Daphne S C Lee Tien Y Wong Maartje J Hooning John W M Martens J Margriet Collée Carolien H M van Deurzen John L Hopper Melissa C Southey Helen Tsimiklis Miroslav K Kapuscinski Chen-Yang Shen Pei-Ei Wu Jyh-Cherng Yu Shou-Tung Chen Grethe Grenaker Alnæs Anne-Lise Borresen-Dale Graham G Giles Roger L Milne Catriona McLean Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Shaik Ahmad Bin Syed Buhari Yik Ying Teo Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Hiltrud Brauch Thomas Brüning Yon-Dschun Koto Paolo Radice Paolo Peterlongo Bernardo Bonanni Sara Volorio Thilo Dörk Natalia V Bogdanova Sonja Helbig Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Ute Hamann Diana Torres Wei Zheng Jirong Long Hoda Anton-Culver Susan L Neuhausen Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Ines de Santiago Jason Carroll Carlos Caldas Melissa A Brown Mathieu Lupien Vessela N Kristensen Paul D P Pharoah Georgia Chenevix-Trench Juliet D French Douglas F Easton Alison M Dunning

Nat Commun 2018 04 10;9:16193. Epub 2018 Apr 10.

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http://dx.doi.org/10.1038/ncomms16193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898457PMC
April 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

Authors:
Christos Mikropoulos Christina G Hutten Selkirk Sibel Saya Elizabeth Bancroft Emily Vertosick Tokhir Dadaev Charles Brendler Elizabeth Page Alexander Dias D Gareth Evans Jeanette Rothwell Lovise Maehle Karol Axcrona Kate Richardson Diana Eccles Thomas Jensen Palle J Osther Christi J van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Rachel Hart Wayne Glover Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Jackie Cook Derek J Rosario Saundra S Buys Tom Conner Susan Domchek Jacquelyn Powers Margreet G E M Ausems Manuel R Teixeira Sofia Maia Louise Izatt Rita Schmutzler Kerstin Rhiem William D Foulkes Talia Boshari Rosemarie Davidson Marielle Ruijs Apollonia T J M Helderman-van den Enden Lesley Andrews Lisa Walker Katie Snape Alex Henderson Irene Jobson Geoffrey J Lindeman Annelie Liljegren Marion Harris Muriel A Adank Judy Kirk Amy Taylor Rachel Susman Rakefet Chen-Shtoyerman Nicholas Pachter Allan Spigelman Lucy Side Janez Zgajnar Josefina Mora Carole Brewer Neus Gadea Angela F Brady David Gallagher Theo van Os Alan Donaldson Vigdis Stefansdottir Julian Barwell Paul A James Declan Murphy Eitan Friedman Nicola Nicolai Lynn Greenhalgh Elias Obeid Vedang Murthy Lucia Copakova John McGrath Soo-Hwang Teo Sara Strom Karin Kast Daniel A Leongamornlert Anthony Chamberlain Jenny Pope Anna C Newlin Neil Aaronson Audrey Ardern-Jones Chris Bangma Elena Castro David Dearnaley Jorunn Eyfjord Alison Falconer Christopher S Foster Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Jan Lubinski Eli Marie Grindedal Joanne McKinley Kylie Shackleton Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Karen Tricker Sue Moss Zsofia Kote-Jarai Andrew Vickers Hans Lilja Brian T Helfand Rosalind A Eeles

Br J Cancer 2018 03 6;118(6):e17. Epub 2018 Mar 6.

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http://dx.doi.org/10.1038/bjc.2018.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877440PMC
March 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

Authors:
Christos Mikropoulos Christina G Hutten Selkirk Sibel Saya Elizabeth Bancroft Emily Vertosick Tokhir Dadaev Charles Brendler Elizabeth Page Alexander Dias D Gareth Evans Jeanette Rothwell Lovise Maehle Karol Axcrona Kate Richardson Diana Eccles Thomas Jensen Palle J Osther Christi J van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Rachel Hart Wayne Glover Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Jackie Cook Derek J Rosario Saundra S Buys Tom Conner Susan Domchek Jacquelyn Powers Margreet Gem Ausems Manuel R Teixeira Sofia Maia Louise Izatt Rita Schmutzler Kerstin Rhiem William D Foulkes Talia Boshari Rosemarie Davidson Marielle Ruijs Apollonia Tjm Helderman-van den Enden Lesley Andrews Lisa Walker Katie Snape Alex Henderson Irene Jobson Geoffrey J Lindeman Annelie Liljegren Marion Harris Muriel A Adank Judy Kirk Amy Taylor Rachel Susman Rakefet Chen-Shtoyerman Nicholas Pachter Allan Spigelman Lucy Side Janez Zgajnar Josefina Mora Carole Brewer Neus Gadea Angela F Brady David Gallagher Theo van Os Alan Donaldson Vigdis Stefansdottir Julian Barwell Paul A James Declan Murphy Eitan Friedman Nicola Nicolai Lynn Greenhalgh Elias Obeid Vedang Murthy Lucia Copakova John McGrath Soo-Hwang Teo Sara Strom Karin Kast Daniel A Leongamornlert Anthony Chamberlain Jenny Pope Anna C Newlin Neil Aaronson Audrey Ardern-Jones Chris Bangma Elena Castro David Dearnaley Jorunn Eyfjord Alison Falconer Christopher S Foster Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Jan Lubinski Eli Marie Grindedal Joanne McKinley Kylie Shackleton Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Karen Tricker Sue Moss Zsofia Kote-Jarai Andrew Vickers Hans Lilja Brian T Helfand Rosalind A Eeles

Br J Cancer 2018 01 4;118(2):266-276. Epub 2018 Jan 4.

The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785754PMC
January 2018

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Authors:
Roger L Milne Karoline B Kuchenbaecker Kyriaki Michailidou Jonathan Beesley Siddhartha Kar Sara Lindström Shirley Hui Audrey Lemaçon Penny Soucy Joe Dennis Xia Jiang Asha Rostamianfar Hilary Finucane Manjeet K Bolla Lesley McGuffog Qin Wang Cora M Aalfs Marcia Adams Julian Adlard Simona Agata Shahana Ahmed Habibul Ahsan Kristiina Aittomäki Fares Al-Ejeh Jamie Allen Christine B Ambrosone Christopher I Amos Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Norbert Arnold Kristan J Aronson Bernd Auber Paul L Auer Margreet G E M Ausems Jacopo Azzollini François Bacot Judith Balmaña Monica Barile Laure Barjhoux Rosa B Barkardottir Myrto Barrdahl Daniel Barnes Daniel Barrowdale Caroline Baynes Matthias W Beckmann Javier Benitez Marina Bermisheva Leslie Bernstein Yves-Jean Bignon Kathleen R Blazer Marinus J Blok Carl Blomqvist William Blot Kristie Bobolis Bram Boeckx Natalia V Bogdanova Anders Bojesen Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Aniko Bozsik Angela R Bradbury Judith S Brand Hiltrud Brauch Hermann Brenner Brigitte Bressac-de Paillerets Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Joan Brunet Thomas Brüning Barbara Burwinkel Saundra S Buys Jinyoung Byun Qiuyin Cai Trinidad Caldés Maria A Caligo Ian Campbell Federico Canzian Olivier Caron Angel Carracedo Brian D Carter J Esteban Castelao Laurent Castera Virginie Caux-Moncoutier Salina B Chan Jenny Chang-Claude Stephen J Chanock Xiaoqing Chen Ting-Yuan David Cheng Jocelyne Chiquette Hans Christiansen Kathleen B M Claes Christine L Clarke Thomas Conner Don M Conroy Jackie Cook Emilie Cordina-Duverger Sten Cornelissen Isabelle Coupier Angela Cox David G Cox Simon S Cross Katarina Cuk Julie M Cunningham Kamila Czene Mary B Daly Francesca Damiola Hatef Darabi Rosemarie Davidson Kim De Leeneer Peter Devilee Ed Dicks Orland Diez Yuan Chun Ding Nina Ditsch Kimberly F Doheny Susan M Domchek Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Stéphane Dubois Pierre-Antoine Dugué Martine Dumont Alison M Dunning Lorraine Durcan Miriam Dwek Bernd Dworniczak Diana Eccles Ros Eeles Hans Ehrencrona Ursula Eilber Bent Ejlertsen Arif B Ekici A Heather Eliassen Christoph Engel Mikael Eriksson Laura Fachal Laurence Faivre Peter A Fasching Ulrike Faust Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger William D Foulkes Eitan Friedman Lin Fritschi Debra Frost Marike Gabrielson Pragna Gaddam Marilie D Gammon Patricia A Ganz Susan M Gapstur Judy Garber Vanesa Garcia-Barberan José A García-Sáenz Mia M Gaudet Marion Gauthier-Villars Andrea Gehrig Vassilios Georgoulias Anne-Marie Gerdes Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Paul Goodfellow Mark H Greene Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Daphne Gschwantler-Kaulich Pascal Guénel Qi Guo Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Emily Hallberg Ute Hamann Nathalie Hamel Susan Hankinson Thomas V O Hansen Patricia Harrington Steven N Hart Jaana M Hartikainen Catherine S Healey Alexander Hein Sonja Helbig Alex Henderson Jane Heyworth Belynda Hicks Peter Hillemanns Shirley Hodgson Frans B Hogervorst Antoinette Hollestelle Maartje J Hooning Bob Hoover John L Hopper Chunling Hu Guanmengqian Huang Peter J Hulick Keith Humphreys David J Hunter Evgeny N Imyanitov Claudine Isaacs Motoki Iwasaki Louise Izatt Anna Jakubowska Paul James Ramunas Janavicius Wolfgang Janni Uffe Birk Jensen Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Karin Kast Renske Keeman Michael J Kerin Carolien M Kets Machteld Keupers Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Irene Konstantopoulou Veli-Matti Kosma Vessela N Kristensen Torben A Kruse Ava Kwong Anne-Vibeke Lænkholm Yael Laitman Fiona Lalloo Diether Lambrechts Keren Landsman Christine Lasset Conxi Lazaro Loic Le Marchand Julie Lecarpentier Andrew Lee Eunjung Lee Jong Won Lee Min Hyuk Lee Flavio Lejbkowicz Fabienne Lesueur Jingmei Li Jenna Lilyquist Anne Lincoln Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jennifer T Loud Jan Lubinski Craig Luccarini Michael Lush Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Kathleen E Malone Siranoush Manoukian JoAnn E Manson Sara Margolin John W M Martens Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis Sylvie Mazoyer Catriona McLean Hanne Meijers-Heijboer Primitiva Menéndez Jeffery Meyer Hui Miao Austin Miller Nicola Miller Gillian Mitchell Marco Montagna Kenneth Muir Anna Marie Mulligan Claire Mulot Sue Nadesan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Dieter Niederacher Sune F Nielsen Børge G Nordestgaard Aaron Norman Robert L Nussbaum Edith Olah Olufunmilayo I Olopade Janet E Olson Curtis Olswold Kai-Ren Ong Jan C Oosterwijk Nick Orr Ana Osorio V Shane Pankratz Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Rachel Lloyd Inge Søkilde Pedersen Bernard Peissel Ana Peixoto Jose I A Perez Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Mila Pinchev Dijana Plaseska-Karanfilska Bruce Poppe Mary E Porteous Ross Prentice Nadege Presneau Darya Prokofieva Elizabeth Pugh Miquel Angel Pujana Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Hedy S Rennert Valerie Rhenius Kerstin Rhiem Andrea Richardson Gustavo C Rodriguez Atocha Romero Jane Romm Matti A Rookus Anja Rudolph Thomas Ruediger Emmanouil Saloustros Joyce Sanders Dale P Sandler Suleeporn Sangrajrang Elinor J Sawyer Daniel F Schmidt Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Sheila Seal Leigha Senter Caroline Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Xin Sheng Hermela Shimelis Martha J Shrubsole Xiao-Ou Shu Lucy E Side Christian F Singer Christof Sohn Melissa C Southey John J Spinelli Amanda B Spurdle Christa Stegmaier Dominique Stoppa-Lyonnet Grzegorz Sukiennicki Harald Surowy Christian Sutter Anthony Swerdlow Csilla I Szabo Rulla M Tamimi Yen Y Tan Jack A Taylor Maria-Isabel Tejada Maria Tengström Soo H Teo Mary B Terry Daniel C Tessier Alex Teulé Kathrin Thöne Darcy L Thull Maria Grazia Tibiletti Laima Tihomirova Marc Tischkowitz Amanda E Toland Rob A E M Tollenaar Ian Tomlinson Ling Tong Diana Torres Martine Tranchant Thérèse Truong Kathy Tucker Nadine Tung Jonathan Tyrer Hans-Ulrich Ulmer Celine Vachon Christi J van Asperen David Van Den Berg Ans M W van den Ouweland Elizabeth J van Rensburg Liliana Varesco Raymonda Varon-Mateeva Ana Vega Alessandra Viel Joseph Vijai Daniel Vincent Jason Vollenweider Lisa Walker Zhaoming Wang Shan Wang-Gohrke Barbara Wappenschmidt Clarice R Weinberg Jeffrey N Weitzel Camilla Wendt Jelle Wesseling Alice S Whittemore Juul T Wijnen Walter Willett Robert Winqvist Alicja Wolk Anna H Wu Lucy Xia Xiaohong R Yang Drakoulis Yannoukakos Daniela Zaffaroni Wei Zheng Bin Zhu Argyrios Ziogas Elad Ziv Kristin K Zorn Manuela Gago-Dominguez Arto Mannermaa Håkan Olsson Manuel R Teixeira Jennifer Stone Kenneth Offit Laura Ottini Sue K Park Mads Thomassen Per Hall Alfons Meindl Rita K Schmutzler Arnaud Droit Gary D Bader Paul D P Pharoah Fergus J Couch Douglas F Easton Peter Kraft Georgia Chenevix-Trench Montserrat García-Closas Marjanka K Schmidt Antonis C Antoniou Jacques Simard

Nat Genet 2017 Dec 23;49(12):1767-1778. Epub 2017 Oct 23.

Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808456PMC
December 2017

Association analysis identifies 65 new breast cancer risk loci.

Authors:
Kyriaki Michailidou Sara Lindström Joe Dennis Jonathan Beesley Shirley Hui Siddhartha Kar Audrey Lemaçon Penny Soucy Dylan Glubb Asha Rostamianfar Manjeet K Bolla Qin Wang Jonathan Tyrer Ed Dicks Andrew Lee Zhaoming Wang Jamie Allen Renske Keeman Ursula Eilber Juliet D French Xiao Qing Chen Laura Fachal Karen McCue Amy E McCart Reed Maya Ghoussaini Jason S Carroll Xia Jiang Hilary Finucane Marcia Adams Muriel A Adank Habibul Ahsan Kristiina Aittomäki Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Banu Arun Paul L Auer François Bacot Myrto Barrdahl Caroline Baynes Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Judith S Brand Hiltrud Brauch Paul Brennan Hermann Brenner Louise Brinton Per Broberg Ian W Brock Annegien Broeks Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Katja Butterbach Qiuyin Cai Hui Cai Trinidad Caldés Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Tsun L Chan Ting-Yuan David Cheng Kee Seng Chia Ji-Yeob Choi Hans Christiansen Christine L Clarke Margriet Collée Don M Conroy Emilie Cordina-Duverger Sten Cornelissen David G Cox Angela Cox Simon S Cross Julie M Cunningham Kamila Czene Mary B Daly Peter Devilee Kimberly F Doheny Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Mingajeva Elvira Christoph Engel Mikael Eriksson Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Lin Fritschi Valerie Gaborieau Marike Gabrielson Manuela Gago-Dominguez Yu-Tang Gao Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Nathalie Hamel Susan Hankinson Patricia Harrington Steven N Hart Jaana M Hartikainen Mikael Hartman Alexander Hein Jane Heyworth Belynda Hicks Peter Hillemanns Dona N Ho Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Ming-Feng Hou Chia-Ni Hsiung Guanmengqian Huang Keith Humphreys Junko Ishiguro Hidemi Ito Motoki Iwasaki Hiroji Iwata Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Yoshio Kasuga Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Veli-Matti Kosma Vessela N Kristensen Ute Krüger Ava Kwong Diether Lambrechts Loic Le Marchand Eunjung Lee Min Hyuk Lee Jong Won Lee Chuen Neng Lee Flavio Lejbkowicz Jingmei Li Jenna Lilyquist Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Artitaya Lophatananon Jan Lubinski Craig Luccarini Michael P Lux Edmond S K Ma Robert J MacInnis Tom Maishman Enes Makalic Kathleen E Malone Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian JoAnn E Manson Sara Margolin Shivaani Mariapun Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis James McKay Catriona McLean Hanne Meijers-Heijboer Alfons Meindl Primitiva Menéndez Usha Menon Jeffery Meyer Hui Miao Nicola Miller Nur Aishah Mohd Taib Kenneth Muir Anna Marie Mulligan Claire Mulot Susan L Neuhausen Heli Nevanlinna Patrick Neven Sune F Nielsen Dong-Young Noh Børge G Nordestgaard Aaron Norman Olufunmilayo I Olopade Janet E Olson Håkan Olsson Curtis Olswold Nick Orr V Shane Pankratz Sue K Park Tjoung-Won Park-Simon Rachel Lloyd Jose I A Perez Paolo Peterlongo Julian Peto Kelly-Anne Phillips Mila Pinchev Dijana Plaseska-Karanfilska Ross Prentice Nadege Presneau Darya Prokofyeva Elizabeth Pugh Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Jane Romm Kathryn J Ruddy Thomas Rüdiger Anja Rudolph Matthias Ruebner Emiel J T Rutgers Emmanouil Saloustros Dale P Sandler Suleeporn Sangrajrang Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Rodney J Scott Christopher Scott Sheila Seal Caroline Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Grace Sheng Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Ann Smeets Christof Sohn Melissa C Southey John J Spinelli Christa Stegmaier Sarah Stewart-Brown Jennifer Stone Daniel O Stram Harald Surowy Anthony Swerdlow Rulla Tamimi Jack A Taylor Maria Tengström Soo H Teo Mary Beth Terry Daniel C Tessier Somchai Thanasitthichai Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Ling Tong Diana Torres Thérèse Truong Chiu-Chen Tseng Shoichiro Tsugane Hans-Ulrich Ulmer Giske Ursin Michael Untch Celine Vachon Christi J van Asperen David Van Den Berg Ans M W van den Ouweland Lizet van der Kolk Rob B van der Luijt Daniel Vincent Jason Vollenweider Quinten Waisfisz Shan Wang-Gohrke Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Anna H Wu Lucy Xia Taiki Yamaji Xiaohong R Yang Cheng Har Yip Keun-Young Yoo Jyh-Cherng Yu Wei Zheng Ying Zheng Bin Zhu Argyrios Ziogas Elad Ziv Sunil R Lakhani Antonis C Antoniou Arnaud Droit Irene L Andrulis Christopher I Amos Fergus J Couch Paul D P Pharoah Jenny Chang-Claude Per Hall David J Hunter Roger L Milne Montserrat García-Closas Marjanka K Schmidt Stephen J Chanock Alison M Dunning Stacey L Edwards Gary D Bader Georgia Chenevix-Trench Jacques Simard Peter Kraft Douglas F Easton

Nature 2017 11 23;551(7678):92-94. Epub 2017 Oct 23.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/nature24284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798588PMC
November 2017

Pathological characterisation of male breast cancer: Results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program.

Eur J Cancer 2017 09 11;82:219-227. Epub 2017 Mar 11.

BOOG Study Center/Dutch Breast Cancer Research Group, Amsterdam, The Netherlands; Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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September 2017

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores.

Authors:
Julie Lecarpentier Valentina Silvestri Karoline B Kuchenbaecker Daniel Barrowdale Joe Dennis Lesley McGuffog Penny Soucy Goska Leslie Piera Rizzolo Anna Sara Navazio Virginia Valentini Veronica Zelli Andrew Lee Ali Amin Al Olama Jonathan P Tyrer Melissa Southey Esther M John Thomas A Conner David E Goldgar Saundra S Buys Ramunas Janavicius Linda Steele Yuan Chun Ding Susan L Neuhausen Thomas V O Hansen Ana Osorio Jeffrey N Weitzel Angela Toss Veronica Medici Laura Cortesi Ines Zanna Domenico Palli Paolo Radice Siranoush Manoukian Bernard Peissel Jacopo Azzollini Alessandra Viel Giulia Cini Giuseppe Damante Stefania Tommasi Paolo Peterlongo Florentia Fostira Ute Hamann D Gareth Evans Alex Henderson Carole Brewer Diana Eccles Jackie Cook Kai-Ren Ong Lisa Walker Lucy E Side Mary E Porteous Rosemarie Davidson Shirley Hodgson Debra Frost Julian Adlard Louise Izatt Ros Eeles Steve Ellis Marc Tischkowitz Andrew K Godwin Alfons Meindl Andrea Gehrig Bernd Dworniczak Christian Sutter Christoph Engel Dieter Niederacher Doris Steinemann Eric Hahnen Jan Hauke Kerstin Rhiem Karin Kast Norbert Arnold Nina Ditsch Shan Wang-Gohrke Barbara Wappenschmidt Dorothea Wand Christine Lasset Dominique Stoppa-Lyonnet Muriel Belotti Francesca Damiola Laure Barjhoux Sylvie Mazoyer Mattias Van Heetvelde Bruce Poppe Kim De Leeneer Kathleen B M Claes Miguel de la Hoya Vanesa Garcia-Barberan Trinidad Caldes Pedro Perez Segura Johanna I Kiiski Kristiina Aittomäki Sofia Khan Heli Nevanlinna Christi J van Asperen Tibor Vaszko Miklos Kasler Edith Olah Judith Balmaña Sara Gutiérrez-Enríquez Orland Diez Alex Teulé Angel Izquierdo Esther Darder Joan Brunet Jesús Del Valle Lidia Feliubadalo Miquel Angel Pujana Conxi Lazaro Adalgeir Arason Bjarni A Agnarsson Oskar Th Johannsson Rosa B Barkardottir Elisa Alducci Silvia Tognazzo Marco Montagna Manuel R Teixeira Pedro Pinto Amanda B Spurdle Helene Holland Jong Won Lee Min Hyuk Lee Jihyoun Lee Sung-Won Kim Eunyoung Kang Zisun Kim Priyanka Sharma Timothy R Rebbeck Joseph Vijai Mark Robson Anne Lincoln Jacob Musinsky Pragna Gaddam Yen Y Tan Andreas Berger Christian F Singer Jennifer T Loud Mark H Greene Anna Marie Mulligan Gord Glendon Irene L Andrulis Amanda Ewart Toland Leigha Senter Anders Bojesen Henriette Roed Nielsen Anne-Bine Skytte Lone Sunde Uffe Birk Jensen Inge Sokilde Pedersen Lotte Krogh Torben A Kruse Maria A Caligo Sook-Yee Yoon Soo-Hwang Teo Anna von Wachenfeldt Dezheng Huo Sarah M Nielsen Olufunmilayo I Olopade Katherine L Nathanson Susan M Domchek Christa Lorenchick Rachel C Jankowitz Ian Campbell Paul James Gillian Mitchell Nick Orr Sue Kyung Park Mads Thomassen Kenneth Offit Fergus J Couch Jacques Simard Douglas F Easton Georgia Chenevix-Trench Rita K Schmutzler Antonis C Antoniou Laura Ottini

J Clin Oncol 2017 Jul 27;35(20):2240-2250. Epub 2017 Apr 27.

Julie Lecarpentier, Karoline B. Kuchenbaecker, Daniel Barrowdale, Joe Dennis, Lesley McGuffog, Goska Leslie, Andrew Lee, Ali Amin Al Olama, Jonathan P. Tyrer, Debra Frost, Steve Ellis, Douglas F. Easton, and Antonis C. Antoniou, University of Cambridge; Karoline B. Kuchenbaecker, The Wellcome Trust Sanger Institute, Hinxton; Marc Tischkowitz, Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Cambridge; D. Gareth Evans, Manchester University, Central Manchester University Hospitals NHS Foundation Trust, Manchester; Alex Henderson, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne; Carole Brewer, Royal Devon and Exeter Hospital, Exeter; Diana Eccles, Southampton University Hospitals NHS Trust, Southampton; Jackie Cook, Sheffield Children's Hospital, Sheffield; Kai-ren Ong, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham; Lisa Walker, Churchill Hospital, Oxford; Lucy E. Side, Great Ormond Street Hospital for Children NHS Trust; Shirley Hodgson, St George's, University of London; Louise Izatt, Guy's and St Thomas' NHS Foundation Trust; Ros Eeles, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust; Nick Orr, The Institute of Cancer Research, London; Mary E. Porteous, Western General Hospital, Edinburgh; Rosemarie Davidson, South Glasgow University Hospitals, Glasgow; Julian Adlard, Chapel Allerton Hospital, Leeds, United Kingdom; Valentina Silvestri, Piera Rizzolo, Anna Sara Navazio, Virginia Valentini, Veronica Zelli, and Laura Ottini, Sapienza University of Rome, Rome; Angela Toss, Veronica Medici, and Laura Cortesi, University of Modena and Reggio Emilia, Modena; Ines Zanna and Domenico Palli, Cancer Research and Prevention Institute, Florence; Paolo Radice, Siranoush Manoukian, Bernard Peissel, and Jacopo Azzollini, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale Tumori (INT); Paolo Peterlongo, Italian Foundation for Cancer Research Institute of Molecular Oncology (IFOM), Milan; Alessandra Viel and Giulia Cini, CRO Aviano, National Cancer Institute, Aviano; Giuseppe Damante, University of Udine, Udine; Stefania Tommasi, Istituto Nazionale Tumori "Giovanni Paolo II", Bari; Elisa Alducci, Silvia Tognazzo, and Marco Montagna, Veneto Institute of Oncology IOV - IRCCS, Padua; Maria A. Caligo, University and University Hospital of Pisa, Pisa, Italy; Penny Soucy and Jacques Simard, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec; Anna Marie Mulligan and Irene L. Andrulis, University of Toronto; Gord Glendon and Irene L. Andrulis, Mount Sinai Hospital, Toronto, Ontario, Canada; Melissa Southey, Ian Campbell, Paul James, and Gillian Mitchell, University of Melbourne, Parkville, Victoria; Amanda B. Spurdle, Helene Holland, and Georgia Chenevix-Trench, QIMR Berghofer Medical Research Institute, Brisbane, Queensland; Ian Campbell, Paul James, and Gillian Mitchell, Peter MacCallum Cancer Centre, East Melbourne, New South Wales, Australia; Esther M. John, Cancer Prevention Institute of California, Fremont; Linda Steele, Yuan Chun Ding, Susan L. Neuhausen, and Jeffrey N. Weitzel, City of Hope, Duarte, CA; Thomas A. Conner and Saundra S. Buys, Huntsman Cancer Institute; David E. Goldgar, University of Utah School of Medicine, Salt Lake City, UT; Andrew K. Godwin, University of Kansas Medical Center, Kansas City; Priyanka Sharma, University of Kansas Medical Center, Westwood, KS; Timothy R. Rebbeck, Harvard TH Chan School of Public Health and Dana Farber Cancer Institute, Boston, MA; Joseph Vijai, Mark Robson, Anne Lincoln, Jacob Musinsky, Pragna Gaddam, and Kenneth Offit, Memorial Sloan Kettering Cancer Center, New York, NY; Jennifer T. Loud and Mark H. Greene, National Cancer Institute, Bethesda, MD; Amanda Ewart Toland and Leigha Senter, The Ohio State University, Columbus, OH; Dezheng Huo, Sarah M. Nielsen, and Olufunmilayo I. Olopade, University of Chicago Medical Center, Chicago, IL; Katherine L. Nathanson and Susan M. Domchek, University of Pennsylvania, Philadelphia; Christa Lorenchick and Rachel C. Jankowitz, University of Pittsburgh Medical Center, Pittsburgh, PA; Fergus J. Couch, Mayo Clinic, Rochester, MN; Ramunas Janavicius, State Research Institute Innovative Medicine Center, Vilnius, Lithuania; Thomas V.O. Hansen, Rigshospitalet, Copenhagen University Hospital, Copenhagen; Anders Bojesen and Henriette Roed Nielsen, Vejle Hospital, Vejle; Anne-Bine Skytte, Lone Sunde, and Uffe Birk Jensen, Aarhus University Hospital, Aarhus; Inge Sokilde Pedersen, Aalborg University Hospital, Aalborg; Lotte Krogh, Torben A. Kruse, and Mads Thomassen, Odense University Hospital, Odense, Denmark; Ana Osorio, National Cancer Research Centre and Spanish Network on Rare Diseases; Miguel de la Hoya, Vanesa Garcia-Barberan, Trinidad Caldes, and Pedro Perez Segura, Hospital Clinico San Carlos, El Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid; Judith Balmaña, University Hospital, Vall d'Hebron; Sara Gutiérrez-Enríquez and Orland Diez, Vall d'Hebron Institute of Oncology; Orland Diez, University Hospital Vall d'Hebron; Alex Teulé, Jesús Del Valle, Lidia Feliubadalo, Miquel Angel Pujana, and Conxi Lazaro, Bellvitge Biomedical Research Institute, Catalan Institute of Oncology, Barcelona; Angel Izquierdo, Esther Darder, and Joan Brunet, Institut d'Investigació Biomèdica de Girona, Catalan Institute of Oncology, Girona, Spain; Florentia Fostira, National Centre for Scientific Research "Demokritos," Athens, Greece; Ute Hamann, German Cancer Research Center (DKFZ); Christian Sutter, University Hospital Heidelberg, Heidelberg; Alfons Meindl, Klinikumrechts der Isar, Technical University Munich; Nina Ditsch, Ludwig-Maximilian University, Munich; Andrea Gehrig, University Würzburg, Würzburg; Bernd Dworniczak, University of Münster, Münster; Christoph Engel, University of Leipzig; Dorothea Wand, University Hospital, Leipzig; Dieter Niederacher, University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf; Doris Steinemann, Hannover Medical School, Hannover; Eric Hahnen, Jan Hauke, Kerstin Rhiem, Barbara Wappenschmidt, and Rita K. Schmutzler, University Hospital Cologne, Cologne; Karin Kast, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden; Norbert Arnold, University Hospital of Schleswig-Holstein, Christian-Albrechts University Kiel, Kiel; Shan Wang-Gohrke, University Hospital Ulm, Ulm, Germany; Christine Lasset, Francesca Damiola, and Laure Barjhoux, Centre Léon Bérard; Sylvie Mazoyer, University of Lyon, Lyon; Dominique Stoppa-Lyonnet and Muriel Belotti, Institut Curie, Paris, France; Mattias Van Heetvelde, Bruce Poppe, Kim De Leeneer, and Kathleen B.M. Claes, Ghent University, Gent, Belgium; Johanna I. Kiiski, Sofia Khan, and Heli Nevanlinna, University of Helsinki; Johanna I. Kiiski, Kristiina Aittomäki, Sofia Khan, and Heli Nevanlinna, Helsinki University Hospital, Helsinki, Finland; Christi J. van Asperen, Leiden University Medical Center, Leiden, the Netherlands; Tibor Vaszko, Miklos Kasler, and Edith Olah, National Institute of Oncology, Budapest, Hungary; Adalgeir Arason, Bjarni A. Agnarsson, Oskar Th. Johannsson, and Rosa B. Barkardottir, Landspitali University Hospital and Biomedical Centre, University of Iceland, Reykjavik, Iceland; Manuel R. Teixeira and Pedro Pinto, Portuguese Oncology Institute; Manuel R. Teixeira, Porto University, Porto, Portugal; Jong Won Lee, Ulsan College of Medicine and Asan Medical Center; Min Hyuk Lee and Jihyoun Lee, Soonchunhyang University and Hospital; Sung-Won Kim and Eunyoung Kang, Daerim St Mary's Hospital; Sue Kyung Park, Seoul National University College of Medicine, Seoul; Zisun Kim, Soonchunhyang University Bucheon Hospital, Bucheon, Korea; Yen Y. Tan, Andreas Berger, and Christian F. Singer, Medical University of Vienna, Vienna, Austria; Sook-Yee Yoon and Soo-Hwang Teo, Sime Darby Medical Centre, Subang Jaya, Malaysia; and Anna von Wachenfeldt, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1200/JCO.2016.69.4935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501359PMC
July 2017

Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.

Authors:
Hermela Shimelis Romy L S Mesman Catharina Von Nicolai Asa Ehlen Lucia Guidugli Charlotte Martin Fabienne M G R Calléja Huong Meeks Emily Hallberg Jamie Hinton Jenna Lilyquist Chunling Hu Cora M Aalfs Kristiina Aittomäki Irene Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Javier Benitez Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Barbara Brouwers Thomas Brüning Barbara Burwinkel Jenny Chang-Claude Georgia Chenevix-Trench Ching-Yu Cheng Ji-Yeob Choi J Margriet Collée Angela Cox Simon S Cross Kamila Czene Hatef Darabi Joe Dennis Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning Peter A Fasching Jonine Figueroa Henrik Flyger Montserrat García-Closas Graham G Giles Gord Glendon Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Mikael Hartman Frans B Hogervorst Antoinette Hollestelle John L Hopper Hidemi Ito Anna Jakubowska Daehee Kang Veli-Matti Kosma Vessela Kristensen Kah-Nyin Lai Diether Lambrechts Loic Le Marchand Jingmei Li Annika Lindblom Artitaya Lophatananon Jan Lubinski Eva Machackova Arto Mannermaa Sara Margolin Frederik Marme Keitaro Matsuo Hui Miao Kyriaki Michailidou Roger L Milne Kenneth Muir Susan L Neuhausen Heli Nevanlinna Janet E Olson Curtis Olswold Jan J C Oosterwijk Ana Osorio Paolo Peterlongo Julian Peto Paul D P Pharoah Katri Pylkäs Paolo Radice Muhammad Usman Rashid Valerie Rhenius Anja Rudolph Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Minouk J Schoemaker Caroline Seynaeve Mitul Shah Chen-Yang Shen Martha Shrubsole Xiao-Ou Shu Susan Slager Melissa C Southey Daniel O Stram Anthony Swerdlow Soo H Teo Ian Tomlinson Diana Torres Thérèse Truong Christi J van Asperen Lizet E van der Kolk Qin Wang Robert Winqvist Anna H Wu Jyh-Cherng Yu Wei Zheng Ying Zheng Jennifer Leary Logan Walker Lenka Foretova Florentia Fostira Kathleen B M Claes Liliana Varesco Setareh Moghadasi Douglas F Easton Amanda Spurdle Peter Devilee Harry Vrieling Alvaro N A Monteiro David E Goldgar Aura Carreira Maaike P G Vreeswijk Fergus J Couch

Cancer Res 2017 06 10;77(11):2789-2799. Epub 2017 Mar 10.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508554PMC
June 2017

Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility Gene XRCC2.

Hum Mutat 2016 09 17;37(9):914-25. Epub 2016 Jun 17.

Department of Human Genetics, Leiden University Medical Center, Leiden, 2300, RC, The Netherlands.

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http://dx.doi.org/10.1002/humu.23019DOI Listing
September 2016

Bias Explains Most of the Parent-of-Origin Effect on Breast Cancer Risk in BRCA1/2 Mutation Carriers.

Cancer Epidemiol Biomarkers Prev 2016 08 8;25(8):1251-8. Epub 2016 Jun 8.

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0182DOI Listing
August 2016

Do BRCA1/2 mutation carriers have an earlier onset of natural menopause?

Menopause 2016 08;23(8):903-10

1Department of Reproductive Medicine 2Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands 3Department of Epidemiology 4Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands 5Department of Genetics, Groningen University, University Medical Center, Groningen, The Netherlands 6Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands 7GROW, School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands 8Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands 9Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands 10Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands 11Department of Obstetrics and Gynaecology, Division of Gynaecology Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands 12Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/GME.0000000000000633DOI Listing
August 2016

Germline BRCA1/2 mutation testing is indicated in every patient with epithelial ovarian cancer: A systematic review.

Eur J Cancer 2016 07 19;61:137-45. Epub 2016 May 19.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2016.03.009DOI Listing
July 2016

Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms.

Hum Mol Genet 2016 06 23;25(11):2256-2268. Epub 2016 Mar 23.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081057PMC
June 2016

Classification and Clinical Management of Variants of Uncertain Significance in High Penetrance Cancer Predisposition Genes.

Hum Mutat 2016 Apr 5;37(4):331-6. Epub 2016 Feb 5.

Department of Clinical Genetics, Leiden University Medical Centre, Leiden, 2333 ZA, The Netherlands.

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April 2016

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization.

Authors:
Ben Zhang Xiao-Ou Shu Ryan J Delahanty Chenjie Zeng Kyriaki Michailidou Manjeet K Bolla Qin Wang Joe Dennis Wanqing Wen Jirong Long Chun Li Alison M Dunning Jenny Chang-Claude Mitul Shah Barbara J Perkins Kamila Czene Hatef Darabi Mikael Eriksson Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Patrick Neven Hans Wildiers Giuseppe Floris Marjanka K Schmidt Matti A Rookus Katja van den Hurk Wim L A M de Kort Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jingmei Li Keith Humphreys Judith Brand Pascal Guénel Thérèse Truong Emilie Cordina-Duverger Florence Menegaux Barbara Burwinkel Frederik Marme Rongxi Yang Harald Surowy Javier Benitez M Pilar Zamora Jose I A Perez Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Georgia Chenevix-Trench Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Annika Lindblom Sara Margolin Maartje J Hooning John W M Martens Madeleine M A Tilanus-Linthorst J Margriet Collée John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Graham G Giles Roger L Milne Catriona McLean Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Anthony J Swerdlow Alan Ashworth Nick Orr Michael Jones Jonine Figueroa Montserrat Garcia-Closas Louise Brinton Jolanta Lissowska Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Paolo Peterlongo Siranoush Manoukian Bernardo Bonanni Paolo Radice Natalia Bogdanova Natalia Antonenkova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubiński Katarzyna Jaworska-Bieniek Katarzyna Durda Ute Hamann Diana Torres Rita K Schmutzler Susan L Neuhausen Hoda Anton-Culver Vessela N Kristensen Grethe I Grenaker Alnæs Brandon L Pierce Peter Kraft Ulrike Peters Sara Lindstrom Daniela Seminara Stephen Burgess Habibul Ahsan Alice S Whittemore Esther M John Marilie D Gammon Kathleen E Malone Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Paul D P Pharoah Jacques Simard Per Hall David J Hunter Douglas F Easton Wei Zheng

J Natl Cancer Inst 2015 Nov 20;107(11). Epub 2015 Aug 20.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center (BZ, XOS, RJD, CZ, WW, JL, WZ) and Department of Biostatistics (CL), Vanderbilt University School of Medicine, Nashville, TN; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care(KM, MKB, QW, JD, PDPP, DFE) and Department of Oncology (AMD, MS, BJP, CL, CB, SA, MM, CSH, PDPP, DFE), University of Cambridge, Cambridge, UK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (KC, HD, ME); Copenhagen General Population Study (SEB, BGN, SFN), Department of Clinical Biochemistry (SEB, BGN, SFN), and Department of Breast Surgery (HF), Herlev Hospital, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (SEB, BGN); Vesalius Research Center (VRC), VIB, Leuven, Belgium (DL); Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium (DL); University Hospitals Leuven and Department of Oncology, Leuven, Belgium (PN, HW, GF); Netherlands Cancer Institute, Amsterdam, the Netherlands (MKS, MAR); Division Research, Department of Donor Studies, Sanquin Blood Supply, Amsterdam, the Netherlands (KVDH, WLAMDK); Department of Laboratory Medicine and Pathology (FJC) and Department of Health Sciences Research (JEO, EH, CV, SS), Mayo Clinic, Rochester, MN; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany (JCC, AR, PS); Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (DFJ); Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK (JP, IDSS); Breakthrough Breast Cancer Research Centre, the Institute of Cancer Research, London, UK (OF, NJ); Department of Obstetrics and Gynecology (HN, TAM), D

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http://dx.doi.org/10.1093/jnci/djv219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643630PMC
November 2015

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor.

Authors:
Paolo Peterlongo Irene Catucci Mara Colombo Laura Caleca Eliseos Mucaki Massimo Bogliolo Maria Marin Francesca Damiola Loris Bernard Valeria Pensotti Sara Volorio Valentina Dall'Olio Alfons Meindl Claus Bartram Christian Sutter Harald Surowy Valérie Sornin Marie-Gabrielle Dondon Séverine Eon-Marchais Dominique Stoppa-Lyonnet Nadine Andrieu Olga M Sinilnikova Gillian Mitchell Paul A James Ella Thompson Marina Marchetti Cristina Verzeroli Carmen Tartari Gabriele Lorenzo Capone Anna Laura Putignano Maurizio Genuardi Veronica Medici Isabella Marchi Massimo Federico Silvia Tognazzo Laura Matricardi Simona Agata Riccardo Dolcetti Lara Della Puppa Giulia Cini Viviana Gismondi Valeria Viassolo Chiara Perfumo Maria Antonietta Mencarelli Margherita Baldassarri Bernard Peissel Gaia Roversi Valentina Silvestri Piera Rizzolo Francesca Spina Caterina Vivanet Maria Grazia Tibiletti Maria Adelaide Caligo Gaetana Gambino Stefania Tommasi Brunella Pilato Carlo Tondini Chiara Corna Bernardo Bonanni Monica Barile Ana Osorio Javier Benitez Luisa Balestrino Laura Ottini Siranoush Manoukian Marco A Pierotti Alessandra Renieri Liliana Varesco Fergus J Couch Xianshu Wang Peter Devilee Florentine S Hilbers Christi J van Asperen Alessandra Viel Marco Montagna Laura Cortesi Orland Diez Judith Balmaña Jan Hauke Rita K Schmutzler Laura Papi Miguel Angel Pujana Conxi Lázaro Anna Falanga Kenneth Offit Joseph Vijai Ian Campbell Barbara Burwinkel Anders Kvist Hans Ehrencrona Sylvie Mazoyer Sara Pizzamiglio Paolo Verderio Jordi Surralles Peter K Rogan Paolo Radice

Hum Mol Genet 2015 Sep 30;24(18):5345-55. Epub 2015 Jun 30.

IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy, Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine.

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http://dx.doi.org/10.1093/hmg/ddv251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550823PMC
September 2015

MicroRNA related polymorphisms and breast cancer risk.

Authors:
Sofia Khan Dario Greco Kyriaki Michailidou Roger L Milne Taru A Muranen Tuomas Heikkinen Kirsimari Aaltonen Joe Dennis Manjeet K Bolla Jianjun Liu Per Hall Astrid Irwanto Keith Humphreys Jingmei Li Kamila Czene Jenny Chang-Claude Rebecca Hein Anja Rudolph Petra Seibold Dieter Flesch-Janys Olivia Fletcher Julian Peto Isabel dos Santos Silva Nichola Johnson Lorna Gibson Zoe Aitken John L Hopper Helen Tsimiklis Minh Bui Enes Makalic Daniel F Schmidt Melissa C Southey Carmel Apicella Jennifer Stone Quinten Waisfisz Hanne Meijers-Heijboer Muriel A Adank Rob B van der Luijt Alfons Meindl Rita K Schmutzler Bertram Müller-Myhsok Peter Lichtner Clare Turnbull Nazneen Rahman Stephen J Chanock David J Hunter Angela Cox Simon S Cross Malcolm W R Reed Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Frans B Hogervorst Peter A Fasching Michael G Schrauder Arif B Ekici Matthias W Beckmann Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Javier Benitez Pilar M Zamora Jose I A Perez Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Paul D P Pharoah Alison M Dunning Mitul Shah Robert Luben Judith Brown Fergus J Couch Xianshu Wang Celine Vachon Janet E Olson Diether Lambrechts Matthieu Moisse Robert Paridaens Marie-Rose Christiaens Pascal Guénel Thérèse Truong Pierre Laurent-Puig Claire Mulot Frederick Marme Barbara Burwinkel Andreas Schneeweiss Christof Sohn Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Irene L Andrulis Julia A Knight Sandrine Tchatchou Anna Marie Mulligan Thilo Dörk Natalia V Bogdanova Natalia N Antonenkova Hoda Anton-Culver Hatef Darabi Mikael Eriksson Montserrat Garcia-Closas Jonine Figueroa Jolanta Lissowska Louise Brinton Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J van Asperen Vessela N Kristensen Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Annika Lindblom Sara Margolin Paolo Radice Paolo Peterlongo Monica Barile Paolo Mariani Maartje J Hooning John W M Martens J Margriet Collée Agnes Jager Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Graham G Giles Catriona McLean Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Arto Mannermaa Ute Hamann Georgia Chenevix-Trench Carl Blomqvist Kristiina Aittomäki Douglas F Easton Heli Nevanlinna

PLoS One 2014 12;9(11):e109973. Epub 2014 Nov 12.

Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229095PMC
July 2015

Next-generation diagnostics: gene panel, exome, or whole genome?

Hum Mutat 2015 Jun 17;36(6):648-55. Epub 2015 Apr 17.

Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/humu.22783DOI Listing
June 2015

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

Authors:
Nick Orr Frank Dudbridge Nicola Dryden Sarah Maguire Daniela Novo Eleni Perrakis Nichola Johnson Maya Ghoussaini John L Hopper Melissa C Southey Carmel Apicella Jennifer Stone Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Frans B Hogervorst Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Lorna Gibson Zoe Aitken Helen Warren Elinor Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Barbara Burwinkel Frederik Marme Andreas Schneeweiss Chistof Sohn Pascal Guénel Thérèse Truong Emilie Cordina-Duverger Marie Sanchez Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Javier Benitez Maria Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan L Neuhausen Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Ute Hamann Hiltrud Brauch Christina Justenhoven Thomas Brüning Yon-Dschun Ko Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Sofia Khan Natalia Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Jonathan Beesley Diether Lambrechts Matthieu Moisse Guiseppe Floris Benoit Beuselinck Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernard Peissel Valeria Pensotti Fergus J Couch Janet E Olson Seth Slettedahl Celine Vachon Graham G Giles Roger L Milne Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robertus A E M Tollenaar Caroline M Seynaeve Christi J Van Asperen Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Maartje J Hooning Antoinette Hollestelle Carolien H M van Deurzen Mieke Kriege Per Hall Jingmei Li Jianjun Liu Keith Humphreys Angela Cox Simon S Cross Malcolm W R Reed Paul D P Pharoah Alison M Dunning Mitul Shah Barbara J Perkins Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Alan Ashworth Anthony Swerdlow Michael Jones Minouk J Schoemaker Alfons Meindl Rita K Schmutzler Curtis Olswold Susan Slager Amanda E Toland Drakoulis Yannoukakos Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Keitaro Matsuo Hidema Ito Hiroji Iwata Junko Ishiguro Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Soo Hwang Teo Cheng Har Yip Peter Kang Mohammad Kamran Ikram Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Mikael Hartman Hui Miao Wei Yen Lim Soo Chin Lee Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James Mckay Pei-Ei Wu Ming-Feng Hou Jyh-Cherng Yu Chen-Yang Shen William Blot Qiuyin Cai Lisa B Signorello Craig Luccarini Caroline Bayes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot David J Hunter Sara Lindstrom Joe Dennis Kyriaki Michailidou Manjeet K Bolla Douglas F Easton Isabel dos Santos Silva Olivia Fletcher Julian Peto

Hum Mol Genet 2015 May 4;24(10):2966-84. Epub 2015 Feb 4.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406292PMC
May 2015

Prediction of breast cancer risk based on profiling with common genetic variants.

Authors:
Nasim Mavaddat Paul D P Pharoah Kyriaki Michailidou Jonathan Tyrer Mark N Brook Manjeet K Bolla Qin Wang Joe Dennis Alison M Dunning Mitul Shah Robert Luben Judith Brown Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Kamila Czene Hatef Darabi Mikael Eriksson Julian Peto Isabel Dos-Santos-Silva Frank Dudbridge Nichola Johnson Marjanka K Schmidt Annegien Broeks Senno Verhoef Emiel J Rutgers Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Fergus J Couch Janet E Olson Celine Vachon Vernon S Pankratz Diether Lambrechts Hans Wildiers Chantal Van Ongeval Erik van Limbergen Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Amy Trentham-Dietz Polly Newcomb Linda Titus Kathleen M Egan David J Hunter Sara Lindstrom Rulla M Tamimi Peter Kraft Nazneen Rahman Clare Turnbull Anthony Renwick Sheila Seal Jingmei Li Jianjun Liu Keith Humphreys Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Hoda Anton-Culver Susan L Neuhausen Argyrios Ziogas Leslie Bernstein Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J van Asperen Angela Cox Simon S Cross Malcolm W R Reed Elza Khusnutdinova Marina Bermisheva Darya Prokofyeva Zalina Takhirova Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Peter Schürmann Michael Bremer Hans Christiansen Tjoung-Won Park-Simon Peter Hillemanns Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Paolo Radice Paolo Peterlongo Siranoush Manoukian Valeria Pensotti John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Alice J Sigurdson Michele M Doody Ute Hamann Diana Torres Hans-Ulrich Ulmer Asta Försti Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Georgia Chenevix-Trench Rosemary Balleine Graham G Giles Roger L Milne Catriona McLean Annika Lindblom Sara Margolin Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Ursula Eilber Shan Wang-Gohrke Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Linetta B Koppert Jane Carpenter Christine Clarke Rodney Scott Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Hermann Brenner Volker Arndt Christa Stegmaier Aida Karina Dieffenbach Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Kenneth Offit Joseph Vijai Mark Robson Rohini Rau-Murthy Miriam Dwek Ruth Swann Katherine Annie Perkins Mark S Goldberg France Labrèche Martine Dumont Diana M Eccles William J Tapper Sajjad Rafiq Esther M John Alice S Whittemore Susan Slager Drakoulis Yannoukakos Amanda E Toland Song Yao Wei Zheng Sandra L Halverson Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Jacques Simard Per Hall Douglas F Easton Montserrat Garcia-Closas

J Natl Cancer Inst 2015 May 8;107(5). Epub 2015 Apr 8.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (NM, PDPP, KM, MKB, QW, JD, RL, JBr, DFE); Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK (PDPP, JT, AMD, MS, CL, CB, SA, MM, CSH, DFE); Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK (MNB, ASw, MJS); Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (HF); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (KC, HD, ME, KH, PHa); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK (JP, IdSS, FD); Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK (NJ, AA, NO, MGC); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, AB, SV, EJR); Division of Breast Cancer Research, Institute of Cancer Research, London, UK (ASw); Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (JF, SJC, LB, ASi, MD); Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland (JLis); Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (FJC); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (JEO, CV, VSP, SS); Vesalius Research Center, VIB, Leuven, Belgium (DL); Laboratory for Translational Genetics, Department of Oncology, University of

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754625PMC
May 2015

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

Authors:
Kyriaki Michailidou Jonathan Beesley Sara Lindstrom Sander Canisius Joe Dennis Michael J Lush Mel J Maranian Manjeet K Bolla Qin Wang Mitul Shah Barbara J Perkins Kamila Czene Mikael Eriksson Hatef Darabi Judith S Brand Stig E Bojesen Børge G Nordestgaard Henrik Flyger Sune F Nielsen Nazneen Rahman Clare Turnbull Olivia Fletcher Julian Peto Lorna Gibson Isabel dos-Santos-Silva Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Ursula Eilber Sabine Behrens Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Sofia Khan Kirsimari Aaltonen Habibul Ahsan Muhammad G Kibriya Alice S Whittemore Esther M John Kathleen E Malone Marilie D Gammon Regina M Santella Giske Ursin Enes Makalic Daniel F Schmidt Graham Casey David J Hunter Susan M Gapstur Mia M Gaudet W Ryan Diver Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Christine D Berg Stephen J Chanock Jonine Figueroa Robert N Hoover Diether Lambrechts Patrick Neven Hans Wildiers Erik van Limbergen Marjanka K Schmidt Annegien Broeks Senno Verhoef Sten Cornelissen Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Quinten Waisfisz Hanne Meijers-Heijboer Muriel A Adank Rob B van der Luijt Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Keun-Young Yoo Keitaro Matsuo Hidemi Ito Hiroji Iwata Kazuo Tajima Pascal Guénel Thérèse Truong Claire Mulot Marie Sanchez Barbara Burwinkel Frederik Marme Harald Surowy Christof Sohn Anna H Wu Chiu-chen Tseng David Van Den Berg Daniel O Stram Anna González-Neira Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Nur Aishah Mohd Taib Gie-Hooi Tan Maartje J Hooning Antoinette Hollestelle John W M Martens J Margriet Collée William Blot Lisa B Signorello Qiuyin Cai John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Ming-Feng Hou Vessela N Kristensen Silje Nord Grethe I Grenaker Alnaes Graham G Giles Roger L Milne Catriona McLean Federico Canzian Dimitrios Trichopoulos Petra Peeters Eiliv Lund Malin Sund Kay-Tee Khaw Marc J Gunter Domenico Palli Lotte Maxild Mortensen Laure Dossus Jose-Maria Huerta Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Kee Seng Chia Ching Wan Chan Peter A Fasching Alexander Hein Matthias W Beckmann Lothar Haeberle Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nick Orr Minouk J Schoemaker Anthony J Swerdlow Louise Brinton Montserrat Garcia-Closas Wei Zheng Sandra L Halverson Martha Shrubsole Jirong Long Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Ute Hamann Thomas Brüning Paolo Radice Paolo Peterlongo Siranoush Manoukian Loris Bernard Natalia V Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska Tomasz Huzarski Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Maria Kabisch Diana Torres Susan L Neuhausen Hoda Anton-Culver Craig Luccarini Caroline Baynes Shahana Ahmed Catherine S Healey Daniel C Tessier Daniel Vincent Francois Bacot Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Jacques Simard Paul P D P Pharoah Peter Kraft Alison M Dunning Georgia Chenevix-Trench Per Hall Douglas F Easton

Nat Genet 2015 Apr 9;47(4):373-80. Epub 2015 Mar 9.

1] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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April 2015

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

Authors:
Maria Kabisch Justo Lorenzo Bermejo Thomas Dünnebier Shibo Ying Kyriaki Michailidou Manjeet K Bolla Qin Wang Joe Dennis Mitul Shah Barbara J Perkins Kamila Czene Hatef Darabi Mikael Eriksson Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Patrick Neven Stephanie Peeters Caroline Weltens Fergus J Couch Janet E Olson Xianshu Wang Kristen Purrington Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel dos-Santos-Silva Nichola Johnson Olivia Fletcher Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Marjanka K Schmidt Annegien Broeks Sten Cornelissen Frans B L Hogervorst Jingmei Li Judith S Brand Keith Humphreys Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marmé Rongxi Yang Peter Bugert Anna González-Neira Javier Benitez M Pilar Zamora Jose I Arias Perez Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle Mieke Kriege Linetta B Koppert John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Seth Slettedahl Amanda E Toland Celine Vachon Drakoulis Yannoukakos Graham G Giles Roger L Milne Catriona McLean Peter A Fasching Matthias Ruebner Arif B Ekici Matthias W Beckmann Hermann Brenner Aida K Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nicholas Orr Minouk J Schoemaker Anthony Swerdlow Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Paolo Radice Paolo Peterlongo Giulietta Scuvera Stefano Fortuzzi Natalia Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Wei Zheng Martha J Shrubsole Qiuyin Cai Diana Torres Hoda Anton-Culver Vessela Kristensen François Bacot Daniel C Tessier Daniel Vincent Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Jacques Simard Georgia Chenevix-Trench Per Hall Paul D P Pharoah Alison M Dunning Douglas F Easton Ute Hamann

Carcinogenesis 2015 Feb 13;36(2):256-71. Epub 2015 Jan 13.

Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335262PMC
February 2015

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

Authors:
Wei-Yu Lin Nicola J Camp Maya Ghoussaini Jonathan Beesley Kyriaki Michailidou John L Hopper Carmel Apicella Melissa C Southey Jennifer Stone Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Emiel J Th Rutgers Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Manjeet K Bolla Qin Wang Joe Dennis Elinor J Sawyer Timothy Cheng Ian Tomlinson Michael J Kerin Nicola Miller Frederik Marmé Harald M Surowy Barbara Burwinkel Pascal Guénel Thérèse Truong Florence Menegaux Claire Mulot Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Alvarez Daniel Herrero Hoda Anton-Culver Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alfons Meindl Peter Lichtner Rita K Schmutzler Bertram Müller-Myhsok Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Daniel C Tessier Daniel Vincent Francois Bacot Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Sofia Khan Keitaro Matsuo Hidemi Ito Hiroji Iwata Akiyo Horio Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Patrick Neven Els Wauters Hans Wildiers Diether Lambrechts Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Siranoush Manoukian Bernardo Bonanni Fergus J Couch Xianshu Wang Celine Vachon Kristen Purrington Graham G Giles Roger L Milne Catriona Mclean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Soo Hwang Teo Cheng Har Yip Norhashimah Hassan Eranga Nishanthie Vithana Vessela Kristensen Wei Zheng Sandra Deming-Halverson Martha J Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Montserrat García-Closas Jonine Figueroa Jolanta Lissowska Louise Brinton Kamila Czene Hatef Darabi Mikael Eriksson Judith S Brand Maartje J Hooning Antoinette Hollestelle Ans M W Van Den Ouweland Agnes Jager Jingmei Li Jianjun Liu Keith Humphreys Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Simon S Cross Malcolm W R Reed William Blot Lisa B Signorello Qiuyin Cai Paul D P Pharoah Barbara Perkins Mitul Shah Fiona M Blows Daehee Kang Keun-Young Yoo Dong-Young Noh Mikael Hartman Hui Miao Kee Seng Chia Thomas Choudary Putti Ute Hamann Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James Mckay Susan Slager Amanda E Toland Drakoulis Yannoukakos Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Shian-Ling Ding Alan Ashworth Michael Jones Nick Orr Anthony J Swerdlow Helen Tsimiklis Enes Makalic Daniel F Schmidt Quang M Bui Stephen J Chanock David J Hunter Rebecca Hein Norbert Dahmen Lars Beckmann Kirsimari Aaltonen Taru A Muranen Tuomas Heikkinen Astrid Irwanto Nazneen Rahman Clare A Turnbull Quinten Waisfisz Hanne E J Meijers-Heijboer Muriel A Adank Rob B Van Der Luijt Per Hall Georgia Chenevix-Trench Alison Dunning Douglas F Easton Angela Cox

Hum Mol Genet 2015 Jan 28;24(1):285-98. Epub 2014 Aug 28.

Department of Oncology, University of Sheffield Medical School, Sheffield S10 2RX, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334820PMC
January 2015

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

Authors:
Dylan M Glubb Mel J Maranian Kyriaki Michailidou Karen A Pooley Kerstin B Meyer Siddhartha Kar Saskia Carlebur Martin O'Reilly Joshua A Betts Kristine M Hillman Susanne Kaufmann Jonathan Beesley Sander Canisius John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Marjanka K Schmidt Annegien Broeks Frans B Hogervorst C Ellen van der Schoot Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Peter A Fasching Matthias Ruebner Arif B Ekici Matthias W Beckmann Julian Peto Isabel dos-Santos-Silva Olivia Fletcher Nichola Johnson Paul D P Pharoah Manjeet K Bolla Qin Wang Joe Dennis Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Barbara Burwinkel Frederik Marme Rongxi Yang Harald Surowy Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Anna González-Neira Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Hoda Anton-Culver Susan L Neuhausen Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alfons Meindl Rita K Schmutzler Hiltrud Brauch Yon-Dschun Ko Thomas Brüning Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Keitaro Matsuo Hidemi Ito Hiroji Iwata Hideo Tanaka Thilo Dörk Natalia V Bogdanova Sonja Helbig Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Anna H Wu Chiu-chen Tseng David Van Den Berg Daniel O Stram Diether Lambrechts Hui Zhao Caroline Weltens Erik van Limbergen Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Petra Seibold Paolo Radice Paolo Peterlongo Monica Barile Fabio Capra Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Graham G Giles Roger L Milne Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Soo Hwang Teo Cheng Har Yip Mee-Hoong See Belinda Cornes Ching-Yu Cheng M Kamran Ikram Vessela Kristensen Wei Zheng Sandra L Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Daniel Klevebring Hatef Darabi Mikael Eriksson Maartje J Hooning Antoinette Hollestelle John W M Martens J Margriet Collée Per Hall Jingmei Li Keith Humphreys Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Simon S Cross Malcolm W R Reed William Blot Lisa B Signorello Qiuyin Cai Mitul Shah Maya Ghoussaini Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Mikael Hartman Hui Miao Wei Yen Lim Anthony Tang Ute Hamann Diana Torres Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Curtis Olswold Susan Slager Amanda E Toland Drakoulis Yannoukakos Chen-Yang Shen Pei-Ei Wu Jyh-Cherng Yu Ming-Feng Hou Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Catherine S Healey Melissa A Brown Bruce A J Ponder Georgia Chenevix-Trench Deborah J Thompson Stacey L Edwards Douglas F Easton Alison M Dunning Juliet D French

Am J Hum Genet 2015 Jan 18;96(1):5-20. Epub 2014 Dec 18.

Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029, Australia; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289692PMC
January 2015

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.

Authors:
Amanda B Spurdle Fergus J Couch Michael T Parsons Lesley McGuffog Daniel Barrowdale Manjeet K Bolla Qin Wang Sue Healey Rita Schmutzler Barbara Wappenschmidt Kerstin Rhiem Eric Hahnen Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Hansjoerg Plendl Dieter Niederacher Christian Sutter Shan Wang-Gohrke Doris Steinemann Sabine Preisler-Adams Karin Kast Raymonda Varon-Mateeva Steve Ellis Debra Frost Radka Platte Jo Perkins D Gareth Evans Louise Izatt Ros Eeles Julian Adlard Rosemarie Davidson Trevor Cole Giulietta Scuvera Siranoush Manoukian Bernardo Bonanni Frederique Mariette Stefano Fortuzzi Alessandra Viel Barbara Pasini Laura Papi Liliana Varesco Rosemary Balleine Katherine L Nathanson Susan M Domchek Kenneth Offitt Anna Jakubowska Noralane Lindor Mads Thomassen Uffe Birk Jensen Johanna Rantala Åke Borg Irene L Andrulis Alexander Miron Thomas V O Hansen Trinidad Caldes Susan L Neuhausen Amanda E Toland Heli Nevanlinna Marco Montagna Judy Garber Andrew K Godwin Ana Osorio Rachel E Factor Mary B Terry Timothy R Rebbeck Beth Y Karlan Melissa Southey Muhammad Usman Rashid Nadine Tung Paul D P Pharoah Fiona M Blows Alison M Dunning Elena Provenzano Per Hall Kamila Czene Marjanka K Schmidt Annegien Broeks Sten Cornelissen Senno Verhoef Peter A Fasching Matthias W Beckmann Arif B Ekici Dennis J Slamon Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Petra Seibold Kristiina Aittomäki Taru A Muranen Päivi Heikkilä Carl Blomqvist Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Janet E Olson Vernon S Pankratz Esther M John Alice S Whittemore Dee W West Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Diana M Eccles William J Tapper Lorraine Durcan Louise Jones Julian Peto Isabel dos-Santos-Silva Olivia Fletcher Nichola Johnson Miriam Dwek Ruth Swann Anita L Bane Gord Glendon Anna M Mulligan Graham G Giles Roger L Milne Laura Baglietto Catriona McLean Jane Carpenter Christine Clarke Rodney Scott Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Angela Cox Simon S Cross Malcolm W R Reed Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Jacek Gronwald Thilo Dörk Natalia Bogdanova Tjoung-Won Park-Simon Peter Hillemanns Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Barbara Burwinkel Frederik Marme Harald Surovy Rongxi Yang Hoda Anton-Culver Argyrios Ziogas Maartje J Hooning J Margriet Collée John W M Martens Madeleine M A Tilanus-Linthorst Hermann Brenner Aida Karina Dieffenbach Volke Arndt Christa Stegmaier Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Annika Lindblom Sara Margolin Vijai Joseph Mark Robson Rohini Rau-Murthy Anna González-Neira José Ignacio Arias Pilar Zamora Javier Benítez Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Paolo Peterlongo Daniela Zaffaroni Monica Barile Fabio Capra Paolo Radice Soo H Teo Douglas F Easton Antonis C Antoniou Georgia Chenevix-Trench David E Goldgar

Breast Cancer Res 2014 Dec 23;16(6):3419. Epub 2014 Dec 23.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352262PMC
December 2014

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study.

Authors:
Elizabeth K Bancroft Elizabeth C Page Elena Castro Hans Lilja Andrew Vickers Daniel Sjoberg Melissa Assel Christopher S Foster Gillian Mitchell Kate Drew Lovise Mæhle Karol Axcrona D Gareth Evans Barbara Bulman Diana Eccles Donna McBride Christi van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Christina Selkirk Peter J Hulick Anders Bojesen Anne-Bine Skytte Jimmy Lam Louise Taylor Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Ignacio Blanco Monica Salinas Jackie Cook Derek J Rosario Saundra Buys Tom Conner Margreet G Ausems Kai-ren Ong Jonathan Hoffman Susan Domchek Jacquelyn Powers Manuel R Teixeira Sofia Maia William D Foulkes Nassim Taherian Marielle Ruijs Apollonia T Helderman-van den Enden Louise Izatt Rosemarie Davidson Muriel A Adank Lisa Walker Rita Schmutzler Kathy Tucker Judy Kirk Shirley Hodgson Marion Harris Fiona Douglas Geoffrey J Lindeman Janez Zgajnar Marc Tischkowitz Virginia E Clowes Rachel Susman Teresa Ramón y Cajal Nicholas Patcher Neus Gadea Allan Spigelman Theo van Os Annelie Liljegren Lucy Side Carole Brewer Angela F Brady Alan Donaldson Vigdis Stefansdottir Eitan Friedman Rakefet Chen-Shtoyerman David J Amor Lucia Copakova Julian Barwell Veda N Giri Vedang Murthy Nicola Nicolai Soo-Hwang Teo Lynn Greenhalgh Sara Strom Alex Henderson John McGrath David Gallagher Neil Aaronson Audrey Ardern-Jones Chris Bangma David Dearnaley Philandra Costello Jorunn Eyfjord Jeanette Rothwell Alison Falconer Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Zsofia Kote-Jarai Jan Lubinski Ulrika Axcrona Jane Melia Joanne McKinley Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Penny Wilson Emma Killick Sue Moss Rosalind A Eeles

Eur Urol 2014 Sep 15;66(3):489-99. Epub 2014 Jan 15.

Oncogenetics Team, Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105321PMC
September 2014

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Authors:
Maya Ghoussaini Stacey L Edwards Kyriaki Michailidou Silje Nord Richard Cowper-Sal Lari Kinjal Desai Siddhartha Kar Kristine M Hillman Susanne Kaufmann Dylan M Glubb Jonathan Beesley Joe Dennis Manjeet K Bolla Qin Wang Ed Dicks Qi Guo Marjanka K Schmidt Mitul Shah Robert Luben Judith Brown Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Bernard Thienpont Patrick Neven Hans Wildiers Annegien Broeks Laura J Van't Veer Emiel J Th Rutgers Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel Dos-Santos-Silva Lorna Gibson Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Per Hall Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Keitaro Matsuo Hidemi Ito Hiroji Iwata Yasushi Yatabe Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Xiao-Ou Shu Wei Lu Yu-Tang Gao Qiuyin Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Daphne S C Lee Tien Y Wong Maartje J Hooning John W M Martens J Margriet Collée Carolien H M van Deurzen John L Hopper Melissa C Southey Helen Tsimiklis Miroslav K Kapuscinski Chen-Yang Shen Pei-Ei Wu Jyh-Cherng Yu Shou-Tung Chen Grethe Grenaker Alnæs Anne-Lise Borresen-Dale Graham G Giles Roger L Milne Catriona McLean Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Shaik Ahmad Bin Syed Buhari Yik Ying Teo Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Hiltrud Brauch Thomas Brüning Yon-Dschun Koto Paolo Radice Paolo Peterlongo Bernardo Bonanni Sara Volorio Thilo Dörk Natalia V Bogdanova Sonja Helbig Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Ute Hamann Diana Torres Wei Zheng Jirong Long Hoda Anton-Culver Susan L Neuhausen Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Alvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Ines de Santiago Jason Carroll Carlos Caldas Melissa A Brown Mathieu Lupien Vessela N Kristensen Paul D P Pharoah Georgia Chenevix-Trench Juliet D French Douglas F Easton Alison M Dunning

Nat Commun 2014 Sep 23;4:4999. Epub 2014 Sep 23.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1038/ncomms5999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321900PMC
September 2014

Meaning-centered group psychotherapy in cancer survivors: a feasibility study.

Psychooncology 2014 Jul 6;23(7):827-31. Epub 2014 Feb 6.

Department of Clinical Psychology, VU University, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/pon.3497DOI Listing
July 2014

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.

Authors:
Ana Osorio Roger L Milne Karoline Kuchenbaecker Tereza Vaclová Guillermo Pita Rosario Alonso Paolo Peterlongo Ignacio Blanco Miguel de la Hoya Mercedes Duran Orland Díez Teresa Ramón Y Cajal Irene Konstantopoulou Cristina Martínez-Bouzas Raquel Andrés Conejero Penny Soucy Lesley McGuffog Daniel Barrowdale Andrew Lee Swe-Brca Brita Arver Johanna Rantala Niklas Loman Hans Ehrencrona Olufunmilayo I Olopade Mary S Beattie Susan M Domchek Katherine Nathanson Timothy R Rebbeck Banu K Arun Beth Y Karlan Christine Walsh Jenny Lester Esther M John Alice S Whittemore Mary B Daly Melissa Southey John Hopper Mary B Terry Saundra S Buys Ramunas Janavicius Cecilia M Dorfling Elizabeth J van Rensburg Linda Steele Susan L Neuhausen Yuan Chun Ding Thomas V O Hansen Lars Jønson Bent Ejlertsen Anne-Marie Gerdes Mar Infante Belén Herráez Leticia Thais Moreno Jeffrey N Weitzel Josef Herzog Kisa Weeman Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Giulietta Scuvera Bernardo Bonanni Frederique Mariette Sara Volorio Alessandra Viel Liliana Varesco Laura Papi Laura Ottini Maria Grazia Tibiletti Paolo Radice Drakoulis Yannoukakos Judy Garber Steve Ellis Debra Frost Radka Platte Elena Fineberg Gareth Evans Fiona Lalloo Louise Izatt Ros Eeles Julian Adlard Rosemarie Davidson Trevor Cole Diana Eccles Jackie Cook Shirley Hodgson Carole Brewer Marc Tischkowitz Fiona Douglas Mary Porteous Lucy Side Lisa Walker Patrick Morrison Alan Donaldson John Kennedy Claire Foo Andrew K Godwin Rita Katharina Schmutzler Barbara Wappenschmidt Kerstin Rhiem Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Hans Jörg Plendl Dieter Niederacher Christian Sutter Shan Wang-Gohrke Doris Steinemann Sabine Preisler-Adams Karin Kast Raymonda Varon-Mateeva Andrea Gehrig Dominique Stoppa-Lyonnet Olga M Sinilnikova Sylvie Mazoyer Francesca Damiola Bruce Poppe Kathleen Claes Marion Piedmonte Kathy Tucker Floor Backes Gustavo Rodríguez Wendy Brewster Katie Wakeley Thomas Rutherford Trinidad Caldés Heli Nevanlinna Kristiina Aittomäki Matti A Rookus Theo A M van Os Lizet van der Kolk J L de Lange Hanne E J Meijers-Heijboer A H van der Hout Christi J van Asperen Encarna B Gómez Garcia Nicoline Hoogerbrugge J Margriet Collée Carolien H M van Deurzen Rob B van der Luijt Peter Devilee Hebon Edith Olah Conxi Lázaro Alex Teulé Mireia Menéndez Anna Jakubowska Cezary Cybulski Jacek Gronwald Jan Lubinski Katarzyna Durda Katarzyna Jaworska-Bieniek Oskar Th Johannsson Christine Maugard Marco Montagna Silvia Tognazzo Manuel R Teixeira Sue Healey Kconfab Investigators Curtis Olswold Lucia Guidugli Noralane Lindor Susan Slager Csilla I Szabo Joseph Vijai Mark Robson Noah Kauff Liying Zhang Rohini Rau-Murthy Anneliese Fink-Retter Christian F Singer Christine Rappaport Daphne Geschwantler Kaulich Georg Pfeiler Muy-Kheng Tea Andreas Berger Catherine M Phelan Mark H Greene Phuong L Mai Flavio Lejbkowicz Irene Andrulis Anna Marie Mulligan Gord Glendon Amanda Ewart Toland Anders Bojesen Inge Sokilde Pedersen Lone Sunde Mads Thomassen Torben A Kruse Uffe Birk Jensen Eitan Friedman Yael Laitman Shani Paluch Shimon Jacques Simard Douglas F Easton Kenneth Offit Fergus J Couch Georgia Chenevix-Trench Antonis C Antoniou Javier Benitez

PLoS Genet 2014 Apr 3;10(4):e1004256. Epub 2014 Apr 3.

Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain; Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain; Genotyping Unit (CeGen), Spanish National Cancer Centre (CNIO), Madrid, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974638PMC
April 2014

Genetic counseling does not fulfill the counselees' need for certainty in hereditary breast/ovarian cancer families: an explorative assessment.

Psychooncology 2013 May 9;22(5):1167-76. Epub 2012 Jul 9.

Department of Clinical Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pon.3125DOI Listing
May 2013

The counselees' self-reported request for psychological help in genetic counseling for hereditary breast/ovarian cancer: not only psychopathology matters.

Psychooncology 2013 Apr 27;22(4):902-10. Epub 2012 Jun 27.

Department of Clinical Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pon.3081DOI Listing
April 2013

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

Authors:
Kyriaki Michailidou Per Hall Anna Gonzalez-Neira Maya Ghoussaini Joe Dennis Roger L Milne Marjanka K Schmidt Jenny Chang-Claude Stig E Bojesen Manjeet K Bolla Qin Wang Ed Dicks Andrew Lee Clare Turnbull Nazneen Rahman Olivia Fletcher Julian Peto Lorna Gibson Isabel Dos Santos Silva Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Kamila Czene Astrid Irwanto Jianjun Liu Quinten Waisfisz Hanne Meijers-Heijboer Muriel Adank Rob B van der Luijt Rebecca Hein Norbert Dahmen Lars Beckman Alfons Meindl Rita K Schmutzler Bertram Müller-Myhsok Peter Lichtner John L Hopper Melissa C Southey Enes Makalic Daniel F Schmidt Andre G Uitterlinden Albert Hofman David J Hunter Stephen J Chanock Daniel Vincent François Bacot Daniel C Tessier Sander Canisius Lodewyk F A Wessels Christopher A Haiman Mitul Shah Robert Luben Judith Brown Craig Luccarini Nils Schoof Keith Humphreys Jingmei Li Børge G Nordestgaard Sune F Nielsen Henrik Flyger Fergus J Couch Xianshu Wang Celine Vachon Kristen N Stevens Diether Lambrechts Matthieu Moisse Robert Paridaens Marie-Rose Christiaens Anja Rudolph Stefan Nickels Dieter Flesch-Janys Nichola Johnson Zoe Aitken Kirsimari Aaltonen Tuomas Heikkinen Annegien Broeks Laura J Van't Veer C Ellen van der Schoot Pascal Guénel Thérèse Truong Pierre Laurent-Puig Florence Menegaux Frederik Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel M Pilar Zamora Jose Ignacio Arias Perez Guillermo Pita M Rosario Alonso Angela Cox Ian W Brock Simon S Cross Malcolm W R Reed Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Brian E Henderson Fredrick Schumacher Loic Le Marchand Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Agnes Jager Quang M Bui Jennifer Stone Gillian S Dite Carmel Apicella Helen Tsimiklis Graham G Giles Gianluca Severi Laura Baglietto Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Jonine Figueroa Jolanta Lissowska Louise Brinton Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Ute Hamann Thomas Brüning Paolo Radice Paolo Peterlongo Siranoush Manoukian Bernardo Bonanni Peter Devilee Rob A E M Tollenaar Caroline Seynaeve Christi J van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Vessela N Kristensen Hoda Anton-Culver Susan Slager Amanda E Toland Stephen Edge Florentia Fostira Daehee Kang Keun-Young Yoo Dong-Young Noh Keitaro Matsuo Hidemi Ito Hiroji Iwata Aiko Sueta Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Soo Hwang Teo Cheng Har Yip Sze Yee Phuah Belinda K Cornes Mikael Hartman Hui Miao Wei Yen Lim Jen-Hwei Sng Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Shian-Ling Ding Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay William J Blot Lisa B Signorello Qiuyin Cai Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Jacques Simard Montse Garcia-Closas Paul D P Pharoah Georgia Chenevix-Trench Alison M Dunning Javier Benitez Douglas F Easton

Nat Genet 2013 Apr;45(4):353-61, 361e1-2

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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April 2013

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

Authors:
Stig E Bojesen Karen A Pooley Sharon E Johnatty Jonathan Beesley Kyriaki Michailidou Jonathan P Tyrer Stacey L Edwards Hilda A Pickett Howard C Shen Chanel E Smart Kristine M Hillman Phuong L Mai Kate Lawrenson Michael D Stutz Yi Lu Rod Karevan Nicholas Woods Rebecca L Johnston Juliet D French Xiaoqing Chen Maren Weischer Sune F Nielsen Melanie J Maranian Maya Ghoussaini Shahana Ahmed Caroline Baynes Manjeet K Bolla Qin Wang Joe Dennis Lesley McGuffog Daniel Barrowdale Andrew Lee Sue Healey Michael Lush Daniel C Tessier Daniel Vincent Françis Bacot Ignace Vergote Sandrina Lambrechts Evelyn Despierre Harvey A Risch Anna González-Neira Mary Anne Rossing Guillermo Pita Jennifer A Doherty Nuria Alvarez Melissa C Larson Brooke L Fridley Nils Schoof Jenny Chang-Claude Mine S Cicek Julian Peto Kimberly R Kalli Annegien Broeks Sebastian M Armasu Marjanka K Schmidt Linde M Braaf Boris Winterhoff Heli Nevanlinna Gottfried E Konecny Diether Lambrechts Lisa Rogmann Pascal Guénel Attila Teoman Roger L Milne Joaquin J Garcia Angela Cox Vijayalakshmi Shridhar Barbara Burwinkel Frederik Marme Rebecca Hein Elinor J Sawyer Christopher A Haiman Shan Wang-Gohrke Irene L Andrulis Kirsten B Moysich John L Hopper Kunle Odunsi Annika Lindblom Graham G Giles Hermann Brenner Jacques Simard Galina Lurie Peter A Fasching Michael E Carney Paolo Radice Lynne R Wilkens Anthony Swerdlow Marc T Goodman Hiltrud Brauch Montserrat Garcia-Closas Peter Hillemanns Robert Winqvist Matthias Dürst Peter Devilee Ingo Runnebaum Anna Jakubowska Jan Lubinski Arto Mannermaa Ralf Butzow Natalia V Bogdanova Thilo Dörk Liisa M Pelttari Wei Zheng Arto Leminen Hoda Anton-Culver Clareann H Bunker Vessela Kristensen Roberta B Ness Kenneth Muir Robert Edwards Alfons Meindl Florian Heitz Keitaro Matsuo Andreas du Bois Anna H Wu Philipp Harter Soo-Hwang Teo Ira Schwaab Xiao-Ou Shu William Blot Satoyo Hosono Daehee Kang Toru Nakanishi Mikael Hartman Yasushi Yatabe Ute Hamann Beth Y Karlan Suleeporn Sangrajrang Susanne 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Jose Ignacio Arias Perez Maureen Hoatlin M Pilar Zamora Linda S Cook Sabapathy P Balasubramanian Linda E Kelemen Andreas Schneeweiss Nhu D Le Christof Sohn Angela Brooks-Wilson Ian Tomlinson Michael J Kerin Nicola Miller Cezary Cybulski Brian E Henderson Janusz Menkiszak Fredrick Schumacher Nicolas Wentzensen Loic Le Marchand Hannah P Yang Anna Marie Mulligan Gord Glendon Svend Aage Engelholm Julia A Knight Claus K Høgdall Carmel Apicella Martin Gore Helen Tsimiklis Honglin Song Melissa C Southey Agnes Jager Ans M Wvan den Ouweland Robert Brown John W M Martens James M Flanagan Mieke Kriege James Paul Sara Margolin Nadeem Siddiqui Gianluca Severi Alice S Whittemore Laura Baglietto Valerie McGuire Christa Stegmaier Weiva Sieh Heiko Müller Volker Arndt France Labrèche Yu-Tang Gao Mark S Goldberg Gong Yang Martine Dumont John R McLaughlin Arndt Hartmann Arif B Ekici Matthias W Beckmann Catherine M Phelan Michael P Lux Jenny Permuth-Wey Bernard Peissel Thomas A Sellers Filomena Ficarazzi Monica Barile Argyrios Ziogas Alan Ashworth Aleksandra Gentry-Maharaj Michael Jones Susan J Ramus Nick Orr Usha Menon Celeste L Pearce Thomas Brüning Malcolm C Pike Yon-Dschun Ko Jolanta Lissowska Jonine Figueroa Jolanta Kupryjanczyk Stephen J Chanock Agnieszka Dansonka-Mieszkowska Arja Jukkola-Vuorinen Iwona K Rzepecka Katri Pylkäs Mariusz Bidzinski Saila Kauppila Antoinette Hollestelle Caroline Seynaeve Rob A E M Tollenaar Katarzyna Durda Katarzyna Jaworska Jaana M Hartikainen Veli-Matti Kosma Vesa Kataja Natalia N Antonenkova Jirong Long Martha Shrubsole Sandra Deming-Halverson Artitaya Lophatananon Pornthep Siriwanarangsan Sarah Stewart-Brown Nina Ditsch Peter Lichtner Rita K Schmutzler Hidemi Ito Hiroji Iwata Kazuo Tajima Chiu-Chen Tseng Daniel O Stram David van den Berg Cheng Har Yip M Kamran Ikram Yew-Ching Teh Hui Cai Wei Lu Lisa B Signorello Qiuyin Cai Dong-Young Noh Keun-Young Yoo Hui Miao Philip Tsau-Choong Iau Yik Ying Teo James McKay Charles Shapiro Foluso Ademuyiwa George Fountzilas Chia-Ni Hsiung Jyh-Cherng Yu Ming-Feng Hou Catherine S Healey Craig Luccarini Susan Peock Dominique Stoppa-Lyonnet Paolo Peterlongo Timothy R Rebbeck Marion Piedmonte Christian F Singer Eitan Friedman Mads Thomassen Kenneth Offit Thomas V O Hansen Susan L Neuhausen Csilla I Szabo Ignacio Blanco Judy Garber Steven A Narod Jeffrey N Weitzel Marco Montagna Edith Olah Andrew K Godwin Drakoulis Yannoukakos David E Goldgar Trinidad Caldes Evgeny N Imyanitov Laima Tihomirova Banu K Arun Ian Campbell Arjen R Mensenkamp Christi J van Asperen Kees E P van Roozendaal Hanne Meijers-Heijboer J Margriet Collée Jan C Oosterwijk Maartje J Hooning Matti A Rookus Rob B van der Luijt Theo A Mvan Os D Gareth Evans Debra Frost Elena Fineberg Julian Barwell Lisa Walker M John Kennedy Radka Platte Rosemarie Davidson Steve D Ellis Trevor Cole Brigitte Bressac-de Paillerets Bruno Buecher Francesca Damiola Laurence Faivre Marc Frenay Olga M Sinilnikova Olivier Caron Sophie Giraud Sylvie Mazoyer Valérie Bonadona Virginie Caux-Moncoutier Aleksandra Toloczko-Grabarek Jacek Gronwald Tomasz Byrski Amanda B Spurdle Bernardo Bonanni Daniela Zaffaroni Giuseppe Giannini Loris Bernard Riccardo Dolcetti Siranoush Manoukian Norbert Arnold Christoph Engel Helmut Deissler Kerstin Rhiem Dieter Niederacher Hansjoerg Plendl Christian Sutter Barbara Wappenschmidt Ake Borg Beatrice Melin Johanna Rantala Maria Soller Katherine L Nathanson Susan M Domchek Gustavo C Rodriguez Ritu Salani Daphne Gschwantler Kaulich Muy-Kheng Tea Shani Shimon Paluch Yael Laitman Anne-Bine Skytte Torben A Kruse Uffe Birk Jensen Mark Robson Anne-Marie Gerdes Bent Ejlertsen Lenka Foretova Sharon A Savage Jenny Lester Penny Soucy Karoline B Kuchenbaecker Curtis Olswold Julie M Cunningham Susan Slager Vernon S Pankratz Ed Dicks Sunil R Lakhani Fergus J Couch Per Hall Alvaro N A Monteiro Simon A Gayther Paul D P Pharoah Roger R Reddel Ellen L Goode Mark H Greene Douglas F Easton Andrew Berchuck Antonis C Antoniou Georgia Chenevix-Trench Alison M Dunning

Nat Genet 2013 Apr;45(4):371-84, 384e1-2

Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ng.2566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670748PMC
April 2013

The effectiveness of a graphical presentation in addition to a frequency format in the context of familial breast cancer risk communication: a multicenter controlled trial.

BMC Med Inform Decis Mak 2013 Apr 29;13:55. Epub 2013 Apr 29.

Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1472-6947-13-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644257PMC
April 2013

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.

Authors:
Tomas Kirchhoff Mia M Gaudet Antonis C Antoniou Lesley McGuffog Manjeet K Humphreys Alison M Dunning Stig E Bojesen Børge G Nordestgaard Henrik Flyger Daehee Kang Keun-Young Yoo Dong-Young Noh Sei-Hyun Ahn Thilo Dork Peter Schürmann Johann H Karstens Peter Hillemanns Fergus J Couch Janet Olson Celine Vachon Xianshu Wang Angela Cox Ian Brock Graeme Elliott Malcolm W R Reed Barbara Burwinkel Alfons Meindl Hiltrud Brauch Ute Hamann Yon-Dschun Ko Annegien Broeks Marjanka K Schmidt Laura J Van 't Veer Linde M Braaf Nichola Johnson Olivia Fletcher Lorna Gibson Julian Peto Clare Turnbull Sheila Seal Anthony Renwick Nazneen Rahman Pei-Ei Wu Jyh-Cherng Yu Chia-Ni Hsiung Chen-Yang Shen Melissa C Southey John L Hopper Fleur Hammet Thijs Van Dorpe Anne-Sophie Dieudonne Sigrid Hatse Diether Lambrechts Irene L Andrulis Natalia Bogdanova Natalia Antonenkova Juri I Rogov Daria Prokofieva Marina Bermisheva Elza Khusnutdinova Christi J van Asperen Robert A E M Tollenaar Maartje J Hooning Peter Devilee Sara Margolin Annika Lindblom Roger L Milne José Ignacio Arias M Pilar Zamora Javier Benítez Gianluca Severi Laura Baglietto Graham G Giles Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Helene Holland Sue Healey Shan Wang-Gohrke Jenny Chang-Claude Arto Mannermaa Veli-Matti Kosma Jaana Kauppinen Vesa Kataja Bjarni A Agnarsson Maria A Caligo Andrew K Godwin Heli Nevanlinna Tuomas Heikkinen Zachary Fredericksen Noralane Lindor Katherine L Nathanson Susan M Domchek Niklas Loman Per Karlsson Marie Stenmark Askmalm Beatrice Melin Anna von Wachenfeldt Frans B L Hogervorst Martijn Verheus Matti A Rookus Caroline Seynaeve Rogier A Oldenburg Marjolijn J Ligtenberg Margreet G E M Ausems Cora M Aalfs Hans J P Gille Juul T Wijnen Encarna B Gómez García Susan Peock Margaret Cook Clare T Oliver Debra Frost Craig Luccarini Gabriella Pichert Rosemarie Davidson Carol Chu Diana Eccles Kai-Ren Ong Jackie Cook Fiona Douglas Shirley Hodgson D Gareth Evans Rosalind Eeles Bert Gold Paul D P Pharoah Kenneth Offit Georgia Chenevix-Trench Douglas F Easton

PLoS One 2012 29;7(6):e35706. Epub 2012 Jun 29.

Memorial Sloan-Kettering Cancer Center (MSKCC): Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America (TK, MG, KO); Department of Environmental Medicine, New York University Cancer Institute, New York University, New York, New York, United States of America (TK), American Cancer Society, Atlanta, Georgia, United States of America (MG).

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November 2012

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers.

Authors:
Yuan C Ding Lesley McGuffog Sue Healey Eitan Friedman Yael Laitman Shani- Paluch-Shimon Bella Kaufman Annelie Liljegren Annika Lindblom Håkan Olsson Ulf Kristoffersson Marie Stenmark-Askmalm Beatrice Melin Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Jacek Gronwald Tomasz Huzarski Cezary Cybulski Tomasz Byrski Ana Osorio Teresa Ramóny Cajal Alexandra V Stavropoulou Javier Benítez Ute Hamann Matti Rookus Cora M Aalfs Judith L de Lange Hanne E J Meijers-Heijboer Jan C Oosterwijk Christi J van Asperen Encarna B Gómez García Nicoline Hoogerbrugge Agnes Jager Rob B van der Luijt Douglas F Easton Susan Peock Debra Frost Steve D Ellis Radka Platte Elena Fineberg D Gareth Evans Fiona Lalloo Louise Izatt Ros Eeles Julian Adlard Rosemarie Davidson Diana Eccles Trevor Cole Jackie Cook Carole Brewer Marc Tischkowitz Andrew K Godwin Harsh Pathak Dominique Stoppa-Lyonnet Olga M Sinilnikova Sylvie Mazoyer Laure Barjhoux Mélanie Léoné Marion Gauthier-Villars Virginie Caux-Moncoutier Antoine de Pauw Agnès Hardouin Pascaline Berthet Hélène Dreyfus Sandra Fert Ferrer Marie-Agnès Collonge-Rame Johanna Sokolowska Saundra Buys Mary Daly Alex Miron Mary Beth Terry Wendy Chung Esther M John Melissa Southey David Goldgar Christian F Singer Muy-Kheng Maria Tea Daphne Gschwantler-Kaulich Anneliese Fink-Retter Thomas V O Hansen Bent Ejlertsen Oskar T Johannsson Kenneth Offit Kara Sarrel Mia M Gaudet Joseph Vijai Mark Robson Marion R Piedmonte Lesley Andrews David Cohn Leslie R DeMars Paul DiSilvestro Gustavo Rodriguez Amanda Ewart Toland Marco Montagna Simona Agata Evgeny Imyanitov Claudine Isaacs Ramunas Janavicius Conxi Lazaro Ignacio Blanco Susan J Ramus Lara Sucheston Beth Y Karlan Jenny Gross Patricia A Ganz Mary S Beattie Rita K Schmutzler Barbara Wappenschmidt Alfons Meindl Norbert Arnold Dieter Niederacher Sabine Preisler-Adams Dorotehea Gadzicki Raymonda Varon-Mateeva Helmut Deissler Andrea Gehrig Christian Sutter Karin Kast Heli Nevanlinna Kristiina Aittomäki Jacques Simard Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Gail E Tomlinson Jeffrey Weitzel Judy E Garber Olufunmilayo I Olopade Wendy S Rubinstein Nadine Tung Joanne L Blum Steven A Narod Sean Brummel Daniel L Gillen Noralane Lindor Zachary Fredericksen Vernon S Pankratz Fergus J Couch Paolo Radice Paolo Peterlongo Mark H Greene Jennifer T Loud Phuong L Mai Irene L Andrulis Gord Glendon Hilmi Ozcelik Anne-Marie Gerdes Mads Thomassen Uffe Birk Jensen Anne-Bine Skytte Maria A Caligo Andrew Lee Georgia Chenevix-Trench Antonis C Antoniou Susan L Neuhausen

Cancer Epidemiol Biomarkers Prev 2012 Aug 22;21(8):1362-70. Epub 2012 Jun 22.

Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415567PMC
August 2012

Urologists' and GPs' knowledge of hereditary prostate cancer is suboptimal for prostate cancer counseling: a nation-wide survey in The Netherlands.

Fam Cancer 2012 Jun;11(2):195-200

Department of Epidemiology, Biostatistics and HTA (133), Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365231PMC
June 2012

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.

Authors:
Susan J Ramus Antonis C Antoniou Karoline B Kuchenbaecker Penny Soucy Jonathan Beesley Xiaoqing Chen Lesley McGuffog Olga M Sinilnikova Sue Healey Daniel Barrowdale Andrew Lee Mads Thomassen Anne-Marie Gerdes Torben A Kruse Uffe Birk Jensen Anne-Bine Skytte Maria A Caligo Annelie Liljegren Annika Lindblom Håkan Olsson Ulf Kristoffersson Marie Stenmark-Askmalm Beatrice Melin Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Elżbieta Złowocka Jacek Gronwald Tomasz Huzarski Tomasz Byrski Cezary Cybulski Aleksandra Toloczko-Grabarek Ana Osorio Javier Benitez Mercedes Duran Maria-Isabel Tejada Ute Hamann Matti Rookus Flora E van Leeuwen Cora M Aalfs Hanne E J Meijers-Heijboer Christi J van Asperen K E P van Roozendaal Nicoline Hoogerbrugge J Margriet Collée Mieke Kriege Rob B van der Luijt Susan Peock Debra Frost Steve D Ellis Radka Platte Elena Fineberg D Gareth Evans Fiona Lalloo Chris Jacobs Ros Eeles Julian Adlard Rosemarie Davidson Diana Eccles Trevor Cole Jackie Cook Joan Paterson Fiona Douglas Carole Brewer Shirley Hodgson Patrick J Morrison Lisa Walker Mary E Porteous M John Kennedy Harsh Pathak Andrew K Godwin Dominique Stoppa-Lyonnet Virginie Caux-Moncoutier Antoine de Pauw Marion Gauthier-Villars Sylvie Mazoyer Mélanie Léoné Alain Calender Christine Lasset Valérie Bonadona Agnès Hardouin Pascaline Berthet Yves-Jean Bignon Nancy Uhrhammer Laurence Faivre Catherine Loustalot Saundra Buys Mary Daly Alex Miron Mary Beth Terry Wendy K Chung Esther M John Melissa Southey David Goldgar Christian F Singer Muy-Kheng Tea Georg Pfeiler Anneliese Fink-Retter Thomas v O Hansen Bent Ejlertsen Oskar Th Johannsson Kenneth Offit Tomas Kirchhoff Mia M Gaudet Joseph Vijai Mark Robson Marion Piedmonte Kelly-Anne Phillips Linda Van Le James S Hoffman Amanda Ewart Toland Marco Montagna Silvia Tognazzo Evgeny Imyanitov Claudine Issacs Ramunas Janavicius Conxi Lazaro Iganacio Blanco Eva Tornero Matilde Navarro Kirsten B Moysich Beth Y Karlan Jenny Gross Edith Olah Tibor Vaszko Soo-Hwang Teo Patricia A Ganz Mary S Beattie Cecelia M Dorfling Elizabeth J van Rensburg Orland Diez Ava Kwong Rita K Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Simone Heidemann Dieter Niederacher Sabine Preisler-Adams Dorotehea Gadzicki Raymonda Varon-Mateeva Helmut Deissler Andrea Gehrig Christian Sutter Karin Kast Britta Fiebig Dieter Schäfer Trinidad Caldes Miguel de la Hoya Heli Nevanlinna Kristiina Aittomäki Marie Plante Amanda B Spurdle Susan L Neuhausen Yuan Chun Ding Xianshu Wang Noralane Lindor Zachary Fredericksen V Shane Pankratz Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Bernardo Bonanni Loris Bernard Riccardo Dolcetti Laura Papi Laura Ottini Paolo Radice Mark H Greene Phuong L Mai Irene L Andrulis Gord Glendon Hilmi Ozcelik Paul D P Pharoah Simon A Gayther Jacques Simard Douglas F Easton Fergus J Couch Georgia Chenevix-Trench

Hum Mutat 2012 Apr 14;33(4):690-702. Epub 2012 Feb 14.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, California, USA.

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April 2012

Exploring the short-term impact of DNA-testing in breast cancer patients: the counselees' perception matters, but the actual BRCA1/2 result does not.

Patient Educ Couns 2012 Feb 27;86(2):239-51. Epub 2011 Dec 27.

Department of Clinical Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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February 2012

Opening the psychological black box in genetic counseling. The psychological impact of DNA testing is predicted by the counselees' perception, the medical impact by the pathogenic or uninformative BRCA1/2-result.

Psychooncology 2012 Jan 11;21(1):29-42. Epub 2010 Nov 11.

Department of Clinical Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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January 2012

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.

Authors:
David G Cox Jacques Simard Daniel Sinnett Yosr Hamdi Penny Soucy Manon Ouimet Laure Barjhoux Carole Verny-Pierre Lesley McGuffog Sue Healey Csilla Szabo Mark H Greene Phuong L Mai Irene L Andrulis Mads Thomassen Anne-Marie Gerdes Maria A Caligo Eitan Friedman Yael Laitman Bella Kaufman Shani S Paluch Åke Borg Per Karlsson Marie Stenmark Askmalm Gisela Barbany Bustinza Katherine L Nathanson Susan M Domchek Timothy R Rebbeck Javier Benítez Ute Hamann Matti A Rookus Ans M W van den Ouweland Margreet G E M Ausems Cora M Aalfs Christi J van Asperen Peter Devilee Hans J J P Gille Susan Peock Debra Frost D Gareth Evans Ros Eeles Louise Izatt Julian Adlard Joan Paterson Jacqueline Eason Andrew K Godwin Marie-Alice Remon Virginie Moncoutier Marion Gauthier-Villars Christine Lasset Sophie Giraud Agnès Hardouin Pascaline Berthet Hagay Sobol François Eisinger Brigitte Bressac de Paillerets Olivier Caron Capucine Delnatte David Goldgar Alex Miron Hilmi Ozcelik Saundra Buys Melissa C Southey Mary Beth Terry Christian F Singer Anne-Catharina Dressler Muy-Kheng Tea Thomas V O Hansen Oskar Johannsson Marion Piedmonte Gustavo C Rodriguez Jack B Basil Stephanie Blank Amanda E Toland Marco Montagna Claudine Isaacs Ignacio Blanco Simon A Gayther Kirsten B Moysich Rita K Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Dieter Niederacher Christian Sutter Dorothea Gadzicki Britta Fiebig Trinidad Caldes Rachel Laframboise Heli Nevanlinna Xiaoqing Chen Jonathan Beesley Amanda B Spurdle Susan L Neuhausen Yuan C Ding Fergus J Couch Xianshu Wang Paolo Peterlongo Siranoush Manoukian Loris Bernard Paolo Radice Douglas F Easton Georgia Chenevix-Trench Antonis C Antoniou Dominique Stoppa-Lyonnet Sylvie Mazoyer Olga M Sinilnikova

Hum Mol Genet 2011 Dec 2;20(23):4732-47. Epub 2011 Sep 2.

INSERM U1052, CNRS UMR5286, Université Lyon 1, Cancer Research Center of Lyon, Lyon, France.

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December 2011

Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers.

Authors:
Kate M Im Tomas Kirchhoff Xianshu Wang Todd Green Clement Y Chow Joseph Vijai Joshua Korn Mia M Gaudet Zachary Fredericksen V Shane Pankratz Candace Guiducci Andrew Crenshaw Lesley McGuffog Christiana Kartsonaki Jonathan Morrison Sue Healey Olga M Sinilnikova Phuong L Mai Mark H Greene Marion Piedmonte Wendy S Rubinstein Frans B Hogervorst Matti A Rookus J Margriet Collée Nicoline Hoogerbrugge Christi J van Asperen Hanne E J Meijers-Heijboer Cees E Van Roozendaal Trinidad Caldes Pedro Perez-Segura Anna Jakubowska Jan Lubinski Tomasz Huzarski Paweł Blecharz Heli Nevanlinna Kristiina Aittomäki Conxi Lazaro Ignacio Blanco Rosa B Barkardottir Marco Montagna Emma D'Andrea Peter Devilee Olufunmilayo I Olopade Susan L Neuhausen Bernard Peissel Bernardo Bonanni Paolo Peterlongo Christian F Singer Gad Rennert Flavio Lejbkowicz Irene L Andrulis Gord Glendon Hilmi Ozcelik Amanda Ewart Toland Maria Adelaide Caligo Mary S Beattie Salina Chan Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Catherine Phelan Steven Narod Esther M John John L Hopper Saundra S Buys Mary B Daly Melissa C Southey Mary-Beth Terry Nadine Tung Thomas V O Hansen Ana Osorio Javier Benitez Mercedes Durán Jeffrey N Weitzel Judy Garber Ute Hamann Susan Peock Margaret Cook Clare T Oliver Debra Frost Radka Platte D Gareth Evans Ros Eeles Louise Izatt Joan Paterson Carole Brewer Shirley Hodgson Patrick J Morrison Mary Porteous Lisa Walker Mark T Rogers Lucy E Side Andrew K Godwin Rita K Schmutzler Barbara Wappenschmidt Yael Laitman Alfons Meindl Helmut Deissler Raymonda Varon-Mateeva Sabine Preisler-Adams Karin Kast Laurence Venat-Bouvet Dominique Stoppa-Lyonnet Georgia Chenevix-Trench Douglas F Easton Robert J Klein Mark J Daly Eitan Friedman Michael Dean Andrew G Clark David M Altshuler Antonis C Antoniou Fergus J Couch Kenneth Offit Bert Gold

Hum Genet 2011 Nov 20;130(5):685-99. Epub 2011 May 20.

Center for Cancer Research, Cancer Inflammation Program, Human Genetics Section, National Cancer Institute, Frederick, MD, USA.

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November 2011

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers.

Breast Cancer Res 2010 29;12(6):R102. Epub 2010 Nov 29.

Division of Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia.

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September 2011

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Authors:
Antonis C Antoniou Christiana Kartsonaki Olga M Sinilnikova Penny Soucy Lesley McGuffog Sue Healey Andrew Lee Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Elisa Cattaneo Monica Barile Valeria Pensotti Barbara Pasini Riccardo Dolcetti Giuseppe Giannini Anna Laura Putignano Liliana Varesco Paolo Radice Phuong L Mai Mark H Greene Irene L Andrulis Gord Glendon Hilmi Ozcelik Mads Thomassen Anne-Marie Gerdes Torben A Kruse Uffe Birk Jensen Dorthe G Crüger Maria A Caligo Yael Laitman Roni Milgrom Bella Kaufman Shani Paluch-Shimon Eitan Friedman Niklas Loman Katja Harbst Annika Lindblom Brita Arver Hans Ehrencrona Beatrice Melin Katherine L Nathanson Susan M Domchek Timothy Rebbeck Ania Jakubowska Jan Lubinski Jacek Gronwald Tomasz Huzarski Tomasz Byrski Cezary Cybulski Bohdan Gorski Ana Osorio Teresa Ramón y Cajal Florentia Fostira Raquel Andrés Javier Benitez Ute Hamann Frans B Hogervorst Matti A Rookus Maartje J Hooning Marcel R Nelen Rob B van der Luijt Theo A M van Os Christi J van Asperen Peter Devilee Hanne E J Meijers-Heijboer Encarna B Gómez Garcia Susan Peock Margaret Cook Debra Frost Radka Platte Jean Leyland D Gareth Evans Fiona Lalloo Ros Eeles Louise Izatt Julian Adlard Rosemarie Davidson Diana Eccles Kai-ren Ong Jackie Cook Fiona Douglas Joan Paterson M John Kennedy Zosia Miedzybrodzka Andrew Godwin Dominique Stoppa-Lyonnet Bruno Buecher Muriel Belotti Carole Tirapo Sylvie Mazoyer Laure Barjhoux Christine Lasset Dominique Leroux Laurence Faivre Myriam Bronner Fabienne Prieur Catherine Nogues Etienne Rouleau Pascal Pujol Isabelle Coupier Marc Frénay John L Hopper Mary B Daly Mary B Terry Esther M John Saundra S Buys Yosuf Yassin Alexander Miron David Goldgar Christian F Singer Muy-Kheng Tea Georg Pfeiler Anne Catharina Dressler Thomas v O Hansen Lars Jønson Bent Ejlertsen Rosa Bjork Barkardottir Tomas Kirchhoff Kenneth Offit Marion Piedmonte Gustavo Rodriguez Laurie Small John Boggess Stephanie Blank Jack Basil Masoud Azodi Amanda Ewart Toland Marco Montagna Silvia Tognazzo Simona Agata Evgeny Imyanitov Ramunas Janavicius Conxi Lazaro Ignacio Blanco Paul D P Pharoah Lara Sucheston Beth Y Karlan Christine S Walsh Edith Olah Aniko Bozsik Soo-Hwang Teo Joyce L Seldon Mary S Beattie Elizabeth J van Rensburg Michelle D Sluiter Orland Diez Rita K Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Ina Ruehl Raymonda Varon-Mateeva Karin Kast Helmut Deissler Dieter Niederacher Norbert Arnold Dorothea Gadzicki Ines Schönbuchner Trinidad Caldes Miguel de la Hoya Heli Nevanlinna Kristiina Aittomäki Martine Dumont Jocelyne Chiquette Marc Tischkowitz Xiaoqing Chen Jonathan Beesley Amanda B Spurdle Susan L Neuhausen Yuan Chun Ding Zachary Fredericksen Xianshu Wang Vernon S Pankratz Fergus Couch Jacques Simard Douglas F Easton Georgia Chenevix-Trench

Hum Mol Genet 2011 Aug 18;20(16):3304-21. Epub 2011 May 18.

Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.

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August 2011

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

Authors:
Annegien Broeks Marjanka K Schmidt Mark E Sherman Fergus J Couch John L Hopper Gillian S Dite Carmel Apicella Letitia D Smith Fleur Hammet Melissa C Southey Laura J Van 't Veer Renate de Groot Vincent T H B M Smit Peter A Fasching Matthias W Beckmann Sebastian Jud Arif B Ekici Arndt Hartmann Alexander Hein Ruediger Schulz-Wendtland Barbara Burwinkel Frederik Marme Andreas Schneeweiss Hans-Peter Sinn Christof Sohn Sandrine Tchatchou Stig E Bojesen Børge G Nordestgaard Henrik Flyger David D Ørsted Diljit Kaur-Knudsen Roger L Milne Jose I Arias Pérez Pilar Zamora Primitiva Menéndez Rodríguez Javier Benítez Hiltrud Brauch Christina Justenhoven Yon-Dschun Ko Ute Hamann Hans-Peter Fischer Thomas Brüning Beate Pesch Jenny Chang-Claude Shan Wang-Gohrke Michael Bremer Johann H Karstens Peter Hillemanns Thilo Dörk Heli A Nevanlinna Tuomas Heikkinen Päivi Heikkilä Carl Blomqvist Kristiina Aittomäki Kirsimari Aaltonen Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Jaana M Kauppinen Vesa Kataja Päivi Auvinen Matti Eskelinen Ylermi Soini Georgia Chenevix-Trench Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Helene Holland Diether Lambrechts Bart Claes Thijs Vandorpe Patrick Neven Hans Wildiers Dieter Flesch-Janys Rebecca Hein Thomas Löning Matthew Kosel Zachary S Fredericksen Xianshu Wang Graham G Giles Laura Baglietto Gianluca Severi Catriona McLean Christopher A Haiman Brian E Henderson Loic Le Marchand Laurence N Kolonel Grethe Grenaker Alnæs Vessela Kristensen Anne-Lise Børresen-Dale David J Hunter Susan E Hankinson Irene L Andrulis Anna Marie Mulligan Frances P O'Malley Peter Devilee Petra E A Huijts Rob A E M Tollenaar Christi J Van Asperen Caroline S Seynaeve Stephen J Chanock Jolanta Lissowska Louise Brinton Beata Peplonska Jonine Figueroa Xiaohong R Yang Maartje J Hooning Antoinette Hollestelle Rogier A Oldenburg Agnes Jager Mieke Kriege Bahar Ozturk Geert J L H van Leenders Per Hall Kamila Czene Keith Humphreys Jianjun Liu Angela Cox Daniel Connley Helen E Cramp Simon S Cross Sabapathy P Balasubramanian Malcolm W R Reed Alison M Dunning Douglas F Easton Manjeet K Humphreys Carlos Caldas Fiona Blows Kristy Driver Elena Provenzano Jan Lubinski Anna Jakubowska Tomasz Huzarski Tomasz Byrski Cezary Cybulski Bohdan Gorski Jacek Gronwald Paul Brennan Suleeporn Sangrajrang Valerie Gaborieau Chen-Yang Shen Chia-Ni Hsiung Jyh-Cherng Yu Shou-Tung Chen Giu-Cheng Hsu Ming-Feng Hou Chiun-Sheng Huang Hoda Anton-Culver Argyrios Ziogas Paul D P Pharoah Montserrat Garcia-Closas

Hum Mol Genet 2011 Aug 19;20(16):3289-303. Epub 2011 May 19.

Department of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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August 2011

Family communication matters: the impact of telling relatives about unclassified variants and uninformative DNA-test results.

Genet Med 2011 Apr;13(4):333-41

Department of Clinical Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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April 2011

Exploring the link between MORF4L1 and risk of breast cancer.

Authors:
Griselda Martrat Christopher M Maxwell Emiko Tominaga Montserrat Porta-de-la-Riva Núria Bonifaci Laia Gómez-Baldó Massimo Bogliolo Conxi Lázaro Ignacio Blanco Joan Brunet Helena Aguilar Juana Fernández-Rodríguez Sheila Seal Anthony Renwick Nazneen Rahman Julia Kühl Kornelia Neveling Detlev Schindler María J Ramírez María Castellà Gonzalo Hernández Douglas F Easton Susan Peock Margaret Cook Clare T Oliver Debra Frost Radka Platte D Gareth Evans Fiona Lalloo Rosalind Eeles Louise Izatt Carol Chu Rosemarie Davidson Kai-Ren Ong Jackie Cook Fiona Douglas Shirley Hodgson Carole Brewer Patrick J Morrison Mary Porteous Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Gaia Roversi Monica Barile Alessandra Viel Barbara Pasini Laura Ottini Anna Laura Putignano Antonella Savarese Loris Bernard Paolo Radice Sue Healey Amanda Spurdle Xiaoqing Chen Jonathan Beesley Matti A Rookus Senno Verhoef Madeleine A Tilanus-Linthorst Maaike P Vreeswijk Christi J Asperen Danielle Bodmer Margreet G E M Ausems Theo A van Os Marinus J Blok Hanne E J Meijers-Heijboer Frans B L Hogervorst David E Goldgar Saundra Buys Esther M John Alexander Miron Melissa Southey Mary B Daly Katja Harbst Ake Borg Johanna Rantala Gisela Barbany-Bustinza Hans Ehrencrona Marie Stenmark-Askmalm Bella Kaufman Yael Laitman Roni Milgrom Eitan Friedman Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Oskar Thor Johannsson Fergus J Couch Xianshu Wang Zachary Fredericksen Daniel Cuadras Víctor Moreno Friederike K Pientka Reinhard Depping Trinidad Caldés Ana Osorio Javier Benítez Juan Bueren Tuomas Heikkinen Heli Nevanlinna Ute Hamann Diana Torres Maria Adelaide Caligo Andrew K Godwin Evgeny N Imyanitov Ramunas Janavicius Olga M Sinilnikova Dominique Stoppa-Lyonnet Sylvie Mazoyer Carole Verny-Pierre Laurent Castera Antoine de Pauw Yves-Jean Bignon Nancy Uhrhammer Jean-Philippe Peyrat Philippe Vennin Sandra Fert Ferrer Marie-Agnès Collonge-Rame Isabelle Mortemousque Lesley McGuffog Georgia Chenevix-Trench Olivia M Pereira-Smith Antonis C Antoniou Julián Cerón Kaoru Tominaga Jordi Surrallés Miguel Angel Pujana

Breast Cancer Res 2011 Apr 5;13(2):R40. Epub 2011 Apr 5.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Institute for Biomedical Research (IDIBELL), Gran Via 199, L'Hospitalet del Llobregat 08908, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219203PMC
April 2011

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers.

Authors:
Susan J Ramus Christiana Kartsonaki Simon A Gayther Paul D P Pharoah Olga M Sinilnikova Jonathan Beesley Xiaoqing Chen Lesley McGuffog Sue Healey Fergus J Couch Xianshu Wang Zachary Fredericksen Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Gaia Roversi Monica Barile Alessandra Viel Anna Allavena Laura Ottini Laura Papi Viviana Gismondi Fabio Capra Paolo Radice Mark H Greene Phuong L Mai Irene L Andrulis Gord Glendon Hilmi Ozcelik Mads Thomassen Anne-Marie Gerdes Torben A Kruse Dorthe Cruger Uffe Birk Jensen Maria Adelaide Caligo Håkan Olsson Ulf Kristoffersson Annika Lindblom Brita Arver Per Karlsson Marie Stenmark Askmalm Ake Borg Susan L Neuhausen Yuan Chun Ding Katherine L Nathanson Susan M Domchek Anna Jakubowska Jan Lubiński Tomasz Huzarski Tomasz Byrski Jacek Gronwald Bohdan Górski Cezary Cybulski Tadeusz Dębniak Ana Osorio Mercedes Durán Maria-Isabel Tejada Javier Benítez Ute Hamann Matti A Rookus Senno Verhoef Madeleine A Tilanus-Linthorst Maaike P Vreeswijk Danielle Bodmer Margreet G E M Ausems Theo A van Os Christi J Asperen Marinus J Blok Hanne E J Meijers-Heijboer Susan Peock Margaret Cook Clare Oliver Debra Frost Alison M Dunning D Gareth Evans Ros Eeles Gabriella Pichert Trevor Cole Shirley Hodgson Carole Brewer Patrick J Morrison Mary Porteous M John Kennedy Mark T Rogers Lucy E Side Alan Donaldson Helen Gregory Andrew Godwin Dominique Stoppa-Lyonnet Virginie Moncoutier Laurent Castera Sylvie Mazoyer Laure Barjhoux Valérie Bonadona Dominique Leroux Laurence Faivre Rosette Lidereau Catherine Nogues Yves-Jean Bignon Fabienne Prieur Marie-Agnès Collonge-Rame Laurence Venat-Bouvet Sandra Fert-Ferrer Alex Miron Saundra S Buys John L Hopper Mary B Daly Esther M John Mary Beth Terry David Goldgar Thomas v O Hansen Lars Jønson Bent Ejlertsen Bjarni A Agnarsson Kenneth Offit Tomas Kirchhoff Joseph Vijai Ana V C Dutra-Clarke Jennifer A Przybylo Marco Montagna Cinzia Casella Evgeny N Imyanitov Ramunas Janavicius Ignacio Blanco Conxi Lázaro Kirsten B Moysich Beth Y Karlan Jenny Gross Mary S Beattie Rita Schmutzler Barbara Wappenschmidt Alfons Meindl Ina Ruehl Britta Fiebig Christian Sutter Norbert Arnold Helmut Deissler Raymonda Varon-Mateeva Karin Kast Dieter Niederacher Dorothea Gadzicki Trinidad Caldes Miguel de la Hoya Heli Nevanlinna Kristiina Aittomäki Jacques Simard Penny Soucy Amanda B Spurdle Helene Holland Georgia Chenevix-Trench Douglas F Easton Antonis C Antoniou

J Natl Cancer Inst 2011 Jan 17;103(2):105-16. Epub 2010 Dec 17.

Department of Gynaecological Oncology, UCL EGA Institute for Women's Health, University College London, London, UK.

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http://dx.doi.org/10.1093/jnci/djq494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107565PMC
January 2011

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

Authors:
Antonis C Antoniou Jonathan Beesley Lesley McGuffog Olga M Sinilnikova Sue Healey Susan L Neuhausen Yuan Chun Ding Timothy R Rebbeck Jeffrey N Weitzel Henry T Lynch Claudine Isaacs Patricia A Ganz Gail Tomlinson Olufunmilayo I Olopade Fergus J Couch Xianshu Wang Noralane M Lindor Vernon S Pankratz Paolo Radice Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Monica Barile Alessandra Viel Anna Allavena Valentina Dall'Olio Paolo Peterlongo Csilla I Szabo Michal Zikan Kathleen Claes Bruce Poppe Lenka Foretova Phuong L Mai Mark H Greene Gad Rennert Flavio Lejbkowicz Gord Glendon Hilmi Ozcelik Irene L Andrulis Mads Thomassen Anne-Marie Gerdes Lone Sunde Dorthe Cruger Uffe Birk Jensen Maria Caligo Eitan Friedman Bella Kaufman Yael Laitman Roni Milgrom Maya Dubrovsky Shimrit Cohen Ake Borg Helena Jernström Annika Lindblom Johanna Rantala Marie Stenmark-Askmalm Beatrice Melin Kate Nathanson Susan Domchek Ania Jakubowska Jan Lubinski Tomasz Huzarski Ana Osorio Adriana Lasa Mercedes Durán Maria-Isabel Tejada Javier Godino Javier Benitez Ute Hamann Mieke Kriege Nicoline Hoogerbrugge Rob B van der Luijt Christi J van Asperen Peter Devilee E J Meijers-Heijboer Marinus J Blok Cora M Aalfs Frans Hogervorst Matti Rookus Margaret Cook Clare Oliver Debra Frost Don Conroy D Gareth Evans Fiona Lalloo Gabriella Pichert Rosemarie Davidson Trevor Cole Jackie Cook Joan Paterson Shirley Hodgson Patrick J Morrison Mary E Porteous Lisa Walker M John Kennedy Huw Dorkins Susan Peock Andrew K Godwin Dominique Stoppa-Lyonnet Antoine de Pauw Sylvie Mazoyer Valérie Bonadona Christine Lasset Hélène Dreyfus Dominique Leroux Agnès Hardouin Pascaline Berthet Laurence Faivre Catherine Loustalot Tetsuro Noguchi Hagay Sobol Etienne Rouleau Catherine Nogues Marc Frénay Laurence Vénat-Bouvet John L Hopper Mary B Daly Mary B Terry Esther M John Saundra S Buys Yosuf Yassin Alexander Miron David Goldgar Christian F Singer Anne Catharina Dressler Daphne Gschwantler-Kaulich Georg Pfeiler Thomas V O Hansen Lars Jønson Bjarni A Agnarsson Tomas Kirchhoff Kenneth Offit Vincent Devlin Ana Dutra-Clarke Marion Piedmonte Gustavo C Rodriguez Katie Wakeley John F Boggess Jack Basil Peter E Schwartz Stephanie V Blank Amanda Ewart Toland Marco Montagna Cinzia Casella Evgeny Imyanitov Laima Tihomirova Ignacio Blanco Conxi Lazaro Susan J Ramus Lara Sucheston Beth Y Karlan Jenny Gross Rita Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Magdalena Lochmann Norbert Arnold Simone Heidemann Raymonda Varon-Mateeva Dieter Niederacher Christian Sutter Helmut Deissler Dorothea Gadzicki Sabine Preisler-Adams Karin Kast Ines Schönbuchner Trinidad Caldes Miguel de la Hoya Kristiina Aittomäki Heli Nevanlinna Jacques Simard Amanda B Spurdle Helene Holland Xiaoqing Chen Radka Platte Georgia Chenevix-Trench Douglas F Easton

Cancer Res 2010 Dec 30;70(23):9742-54. Epub 2010 Nov 30.

Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999830PMC
December 2010

Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers.

Breast Cancer Res Treat 2010 Feb 13;120(1):235-44. Epub 2009 Aug 13.

Department of Epidemiology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-009-0476-0DOI Listing
February 2010

Disentangling the Babylonian speech confusion in genetic counseling: an analysis of the reliability and validity of the nomenclature for BRCA1/2 DNA-test results other than pathogenic.

Genet Med 2009 Oct;11(10):742-9

Department of Clinical Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/GIM.0b013e3181b2e608DOI Listing
October 2009