Publications by authors named "Byron Llerena Zambrano"

3 Publications

  • Page 1 of 1

Soft Electronics Based on Stretchable and Conductive Nanocomposites for Biomedical Applications.

Adv Healthc Mater 2021 02 17;10(3):e2001397. Epub 2020 Nov 17.

Department of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), 333 Techno jungan-dareo, Daegu, 42988, South Korea.

Research on the field of implantable electronic devices that can be directly applied in the body with various functionalities is increasingly intensifying due to its great potential for various therapeutic applications. While conventional implantable electronics generally include rigid and hard conductive materials, their surrounding biological objects are soft and dynamic. The mechanical mismatch between implanted devices and biological environments induces damages in the body especially for long-term applications. Stretchable electronics with outstanding mechanical compliance with biological objects effectively improve such limitations of existing rigid implantable electronics. In this article, the recent progress of implantable soft electronics based on various conductive nanocomposites is systematically described. In particular, representative fabrication approaches of conductive and stretchable nanocomposites for implantable soft electronics and various in vivo applications of implantable soft electronics are focused on. To conclude, challenges and perspectives of current implantable soft electronics that should be considered for further advances are discussed.
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http://dx.doi.org/10.1002/adhm.202001397DOI Listing
February 2021

Continuous Heart Volume Monitoring by Fully Implantable Soft Strain Sensor.

Adv Healthc Mater 2020 10 6;9(19):e2000855. Epub 2020 Sep 6.

Product Development Group Zurich, ETH Zurich, Tannenstrasse 3, Zurich, 8092, Switzerland.

Cardiothoracic open-heart surgery has revolutionized the treatment of cardiovascular disease, the leading cause of death worldwide. After the surgery, hemodynamic and volume management can be complicated, for example in case of vasoplegia after endocarditis. Timely treatment is crucial for outcomes. Currently, treatment decisions are made based on heart volume, which needs to be measured manually by the clinician each time using ultrasound. Alternatively, implantable sensors offer a real-time window into the dynamic function of our body. Here it is shown that a soft flexible sensor, made with biocompatible materials, implanted on the surface of the heart, can provide continuous information of the heart volume after surgery. The sensor works robustly for a period of two days on a tensile machine. The accuracy of measuring heart volume is improved compared to the clinical gold standard in vivo, with an error of 7.1 mL for the strain sensor versus impedance and 14.0 mL versus ultrasound. Implanting such a sensor would provide essential, continuous information on heart volume in the critical time following the surgery, allowing early identification of complications, facilitating treatment, and hence potentially improving patient outcome.
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http://dx.doi.org/10.1002/adhm.202000855DOI Listing
October 2020

Recent Advances in 1D Stretchable Electrodes and Devices for Textile and Wearable Electronics: Materials, Fabrications, and Applications.

Adv Mater 2020 Feb 9;32(5):e1902532. Epub 2019 Sep 9.

School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul, 03722, Republic of Korea.

Research on wearable electronic devices that can be directly integrated into daily textiles or clothes has been explosively grown holding great potential for various practical wearable applications. These wearable electronic devices strongly demand 1D electronic devices that are light-weight, weavable, highly flexible, stretchable, and adaptable to comport to frequent deformations during usage in daily life. To this end, the development of 1D electrodes with high stretchability and electrical performance is fundamentally essential. Herein, the recent process of 1D stretchable electrodes for wearable and textile electronics is described, focusing on representative conductive materials, fabrication techniques for 1D stretchable electrodes with high performance, and designs and applications of various 1D stretchable electronic devices. To conclude, discussions are presented regarding limitations and perspectives of current materials and devices in terms of performance and scientific understanding that should be considered for further advances.
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http://dx.doi.org/10.1002/adma.201902532DOI Listing
February 2020