Byoung Chul Cho

Byoung Chul Cho

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Dual-targeting of EGFR and Neuropilin-1 attenuates resistance to EGFR-targeted antibody therapy in KRAS-mutant non-small cell lung cancer.

Cancer Lett 2019 Dec 12;466:23-34. Epub 2019 Sep 12.

Department of Molecular Science and Technology, Ajou University, Suwon, Republic of Korea; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.09.005DOI Listing
December 2019

Dynamic changes in PD-L1 expression and CD8 T cell infiltration in non-small cell lung cancer following chemoradiation therapy.

Lung Cancer 2019 Oct 1;136:30-36. Epub 2019 Aug 1.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.07.027DOI Listing
October 2019

Real-world use of osimertinib in non-small cell lung cancer: ASTRIS study Korean subgroup analysis.

Curr Med Res Opin 2019 Oct 4. Epub 2019 Oct 4.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.

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http://dx.doi.org/10.1080/03007995.2019.1676708DOI Listing
October 2019

Predictive factors for the development of diabetes in cancer patients treated with phosphatidylinositol 3-kinase inhibitors.

Cancer Chemother Pharmacol 2019 Aug 27;84(2):405-414. Epub 2019 Jun 27.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

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http://dx.doi.org/10.1007/s00280-019-03889-0DOI Listing
August 2019

A phase Ib study of the combination of afatinib and ruxolitinib in EGFR mutant NSCLC with progression on EGFR-TKIs.

Lung Cancer 2019 Aug 28;134:46-51. Epub 2019 May 28.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.05.030DOI Listing
August 2019

NOVA1 induction by inflammation and NOVA1 suppression by epigenetic regulation in head and neck squamous cell carcinoma.

Sci Rep 2019 Aug 2;9(1):11231. Epub 2019 Aug 2.

Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, South Korea.

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http://www.nature.com/articles/s41598-019-47755-8
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http://dx.doi.org/10.1038/s41598-019-47755-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677744PMC
August 2019

Impact of Treatment-Related Lymphopenia on Immunotherapy for Advanced Non-Small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2019 Aug 30. Epub 2019 Aug 30.

Department of Radiation Oncology, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.08.047DOI Listing
August 2019

Osimertinib in Patients with T790M Positive Advanced Non-small Cell Lung Cancer: Korean Subgroup Analysis from Phase II Studies.

Cancer Res Treat 2019 Jul 23. Epub 2019 Jul 23.

Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

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http://dx.doi.org/10.4143/crt.2019.200DOI Listing
July 2019

Comprehensive analysis of the characteristics and treatment outcomes of patients with non-small cell lung cancer treated with anti-PD-1 therapy in real-world practice.

J Cancer Res Clin Oncol 2019 Jun 25;145(6):1613-1623. Epub 2019 Mar 25.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.

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http://link.springer.com/10.1007/s00432-019-02899-y
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http://dx.doi.org/10.1007/s00432-019-02899-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527531PMC
June 2019

Real-World Analysis of the Efficacy of Rebiopsy and Mutation Test of Tissue and Plasma Samples in Drug-Resistant Non-Small Cell Lung Cancer.

Yonsei Med J 2019 Jun;60(6):525-534

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3349/ymj.2019.60.6.525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536394PMC
June 2019

Indoor radon exposure increases tumor mutation burden in never-smoker patients with lung adenocarcinoma.

Lung Cancer 2019 May 3;131:139-146. Epub 2019 Apr 3.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002193038
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http://dx.doi.org/10.1016/j.lungcan.2019.04.002DOI Listing
May 2019

Molecular Diagnostic Assays and Clinicopathologic Implications of MET Exon 14 Skipping Mutation in Non-small-cell Lung Cancer.

Clin Lung Cancer 2019 01 11;20(1):e123-e132. Epub 2018 Oct 11.

Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15257304183026
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http://dx.doi.org/10.1016/j.cllc.2018.10.004DOI Listing
January 2019

Characterization of head and neck squamous cell carcinoma arising in young patients: Particular focus on molecular alteration and tumor immunity.

Head Neck 2019 Jan 10;41(1):198-207. Epub 2018 Dec 10.

Department of Pathology, Yonsei University College of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1002/hed.25507DOI Listing
January 2019

Promising preclinical platform for evaluation of immuno-oncology drugs using Hu-PBL-NSG lung cancer models.

Lung Cancer 2019 01 27;127:112-121. Epub 2018 Nov 27.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183067
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http://dx.doi.org/10.1016/j.lungcan.2018.11.035DOI Listing
January 2019

A man with recurrent hypovolemic shock on anti-programmed cell death protein 1 treatment: Immune-related protein-losing enteropathy.

Eur J Cancer 2018 11 18;104:104-107. Epub 2018 Oct 18.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2018.09.015DOI Listing
November 2018

Establishment of a platform of non-small-cell lung cancer patient-derived xenografts with clinical and genomic annotation.

Lung Cancer 2018 10 11;124:168-178. Epub 2018 Aug 11.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.08.008DOI Listing
October 2018

Characteristics and Outcome of ROS1-Positive Non-Small Cell Lung Cancer Patients in Routine Clinical Practice.

J Thorac Oncol 2018 09 5;13(9):1373-1382. Epub 2018 Jun 5.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.05.026DOI Listing
September 2018

Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer.

Lung Cancer 2018 09 27;123:14-21. Epub 2018 Apr 27.

Aix Marseille University, Jardin du Pharo, 58, bd Charles Livon, 13284 Marseille, France; Assistance Publique Hôpitaux de Marseille, 80, rue Brochier, 13005 Marseille, France; Centre d'Essais Précoces en Cancérologie de Marseille (CLIP(2)), Hôpital La Timone - Basement F, 1st Floor, 264, rue St Pierre, 13885 Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.04.022DOI Listing
September 2018

Nivolumab in advanced non-small-cell lung cancer patients who failed prior platinum-based chemotherapy.

Lung Cancer 2018 08 24;122:234-242. Epub 2018 May 24.

Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-Ro, Gangnam-Gu, Seoul, 06351, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.05.023DOI Listing
August 2018

CNS Response to Osimertinib Versus Standard Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 Aug 28:JCO2018783118. Epub 2018 Aug 28.

Thanyanan Reungwetwattana, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Kazuhiko Nakagawa, Kindai University School of Medicine, Osaka; Naoyuki Nogami, National Hospital Organization Shikoku Cancer Center, Matsuyama; Isamu Okamoto, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Byoung Chul Cho, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul; Eun Kyung Cho, Gachon University Gil Medical Center, Incheon; Ki Hyeong Lee, Chungbuk National University Hospital, Cheong-ju, Republic of Korea; Manuel Cobo, Institute of Biomedical Research in Málaga, Málaga University Hospital Regional, Málaga, Spain; Alessandro Bertolini, Hospital of Sondrio, Sondrio, Italy; Sabine Bohnet, Universitätsklinik Schleswig-Holstein, Lübeck, Germany; Caicun Zhou, Pulmonary Hospital of Tongji University, Shanghai, People's Republic of China; Natasha Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Rachel Hodge, Astrid McKeown, Andrew P. Brown, and Yuri Rukazenkov, AstraZeneca, Cambridge, United Kingdom; Suresh S. Ramalingam, Winship Cancer Institute, Emory University, Atlanta, GA; and Johan Vansteenkiste, University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1200/JCO.2018.78.3118DOI Listing
August 2018

Can We Prevent Resistance to Osimertinib? Combination or Sequential.

J Thorac Oncol 2018 07;13(7):877-879

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.05.012DOI Listing
July 2018

Afatinib in heavily pretreated advanced NSCLC patients who progressed following prior gefitinib or erlotinib: Compassionate use program in Korea.

Lung Cancer 2018 05 6;119:36-41. Epub 2018 Mar 6.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.02.020DOI Listing
May 2018

RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-κB-mediated ERK reactivation.

Cell Death Dis 2018 05 22;9(6):587. Epub 2018 May 22.

Personal Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea.

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http://dx.doi.org/10.1038/s41419-018-0651-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964247PMC
May 2018

A Clinical Trial of Combination Neoadjuvant Chemotherapy and Transoral Robotic Surgery in Patients with T3 and T4 Laryngo-Hypopharyngeal Cancer.

Ann Surg Oncol 2018 Apr 30;25(4):864-871. Epub 2017 Oct 30.

Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.

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http://dx.doi.org/10.1245/s10434-017-6208-5DOI Listing
April 2018

Acquired resistance to EGFR targeted therapy in non-small cell lung cancer: Mechanisms and therapeutic strategies.

Cancer Treat Rev 2018 Apr 20;65:1-10. Epub 2018 Feb 20.

Department of Haematology-Oncology, National University Health System, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2018.02.006DOI Listing
April 2018

Efficacy and safety of vinorelbine plus cisplatin chemotherapy for patients with recurrent and/or metastatic salivary gland cancer of the head and neck.

Head Neck 2018 Jan 16;40(1):55-62. Epub 2017 Oct 16.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1002/hed.24933DOI Listing
January 2018

Impact of Tumor Purity on Immune Gene Expression and Clustering Analyses across Multiple Cancer Types.

Cancer Immunol Res 2018 01 15;6(1):87-97. Epub 2017 Nov 15.

Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Korea.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0201DOI Listing
January 2018

Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.

N Engl J Med 2018 01 18;378(2):113-125. Epub 2017 Nov 18.

From Gustave Roussy Cancer Campus and University Paris-Sud, Orsay, France (J.-C.S., D.P.); the Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo (Y.O.), the Department of Thoracic Oncology, Osaka International Cancer Institute (F.I.), and the Department of Thoracic Oncology, Kansai Medical University Hospital (T.K.), Osaka, the Department of Thoracic Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama (N.N.), and the Research Institute for Diseases of the Chest, Graduate School of Medical Science, Kyushu University, Fukuoka (I.O.) - all in Japan; the Respiratory Oncology Unit, University Hospital KU Leuven, Leuven, Belgium (J.V.); Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok (T.R.), the Oncology Unit, Department of Medicine, Chiang Mai University, Chiang Mai (B.C.), and the Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai (A.D.) - all in Thailand; the Division of Medical Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheong-ju (K.H.L.), the Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (B.C.C.), and the Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon (E.K.C.) - all in South Korea; Pulmonary Hospital of Tongji University, Shanghai (C.Z.), and Jilin Provincial Cancer Hospital, Changchun (Y.C.) - both in China; Hospital Umum Sarawak, Kuching, Malaysia (P.J.V.); National Cheng Kung University, Tainan, Taiwan (W.-C.S.); the Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (J.E.G.); the Department of Oncology, University College London Hospitals Biomedical Research Centre, and the Cancer Research UK Lung Cancer Centre of Excellence, London (S.-M.L.), and AstraZeneca, Cambridge (R.H., M.M., Y.R.) - all in the United Kingdom; and Emory University School of Medicine, Winship Cancer Institute, Atlanta (S.S.R.).

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http://dx.doi.org/10.1056/NEJMoa1713137DOI Listing
January 2018

Immune checkpoint inhibitors in epidermal growth factor receptor mutant non-small cell lung cancer: Current controversies and future directions.

Lung Cancer 2018 01 13;115:12-20. Epub 2017 Nov 13.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.lungcan.2017.11.009DOI Listing
January 2018

Transoral robotic surgery-based therapy in patients with stage III-IV oropharyngeal squamous cell carcinoma.

Oral Oncol 2017 12 21;75:16-21. Epub 2017 Oct 21.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2017.10.014DOI Listing
December 2017

Architectural patterns of p16 immunohistochemical expression associated with cancer immunity and prognosis of head and neck squamous cell carcinoma.

APMIS 2017 Nov 4;125(11):974-984. Epub 2017 Oct 4.

Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/apm.12744DOI Listing
November 2017

Next-generation sequencing reveals novel resistance mechanisms and molecular heterogeneity in EGFR-mutant non-small cell lung cancer with acquired resistance to EGFR-TKIs.

Lung Cancer 2017 11 12;113:106-114. Epub 2017 Sep 12.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea; JE-UK Laboratory of Molecular Cancer Therapeutics, Yonsei Cancer Institute, Yonsei University College of Medicine, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.09.005DOI Listing
November 2017

Phase 2 study of intermittent pulse dacomitinib in patients with advanced non-small cell lung cancers.

Lung Cancer 2017 10 23;112:195-199. Epub 2017 Aug 23.

Lombardi Comprehensive Cancer Center, Georgetown University, 3970 Reservoir Road Washington DC 20007, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.08.017DOI Listing
October 2017

Validation of ALK/ROS1 Dual Break Apart FISH Probe probe in non-small-cell lung cancer.

Lung Cancer 2017 09 12;111:79-83. Epub 2017 Jul 12.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002173039
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http://dx.doi.org/10.1016/j.lungcan.2017.07.016DOI Listing
September 2017

Open-Label, Multicenter, Phase II Study of Ceritinib in Patients With Non-Small-Cell Lung Cancer Harboring ROS1 Rearrangement.

J Clin Oncol 2017 Aug 18;35(23):2613-2618. Epub 2017 May 18.

Sun Min Lim, Hye Ryun Kim, Hyo Sup Shim, Joo-Hang Kim, and Byoung Chul Cho, Yonsei University College of Medicine; Yun-Gyoo Lee, Yoon La Choi, and Myung-Ju Ahn, Sungkyunkwan University School of Medicine; Bong-Seog Kim, VHS Medical Center; Min Jeong Lee and Maria Kim, Yonsei University Health System, Seoul; Jong-Seok Lee and Jin-Haeng Chung, Seoul National University Bundang Hospital, Bundang; Ki Hyeong Lee, Chungbuk National University, Cheongju; Young Joo Min, University of Ulsan College of Medicine, Ulsan; Eun Kyung Cho, Gachon Medical School, Inchon; Sung Sook Lee, Inje University College of Medicine; Moon Young Choi, Inje University, Busan; Jin-Haeng Chung, Seoul National University College of Medicine, Seongnam, Republic of Korea; and Siraj M. Ali, Foundation Medicine, Cambridge, MA.

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http://dx.doi.org/10.1200/JCO.2016.71.3701DOI Listing
August 2017

Treatment options for EGFR mutant NSCLC with CNS involvement-Can patients BLOOM with the use of next generation EGFR TKIs?

Lung Cancer 2017 06 22;108:29-37. Epub 2017 Feb 22.

Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore; School of Surgery, The University of Western Australia, Perth, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.02.012DOI Listing
June 2017

Optimal dose and volume for postoperative radiotherapy in brain oligometastases from lung cancer: a retrospective study.

Radiat Oncol J 2017 Jun 30;35(2):153-162. Epub 2017 Jun 30.

Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3857/roj.2017.00094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518455PMC
June 2017

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

J Clin Oncol 2017 May 13;35(13):1403-1410. Epub 2017 Mar 13.

Oliver Gautschi, Kristin Zeidler, and Joachim Diebold, Lucerne Cantonal Hospital, Luzern; Patrizia Froesch, Ente Ospedaliero Cantonale, Bellinzona; Martin Früh, Kantonsspital St Gallen, St Gallen; Sacha I. Rothschild, University Hospital Basel, Basel, Switzerland; Julie Milia and Julien Mazières, Hôpital Larrey; Thomas Filleron, Institut Universitaire du Cancer, Claudius Regaud, Toulouse; Benjamin Besse and Jordi Remon-Masip, Institute Gustave Roussy, Villejuif; Gérard Zalcman, University Hospital Bichat, Paris; Isabelle Monnet, Centre Hospitalier Intercommunal de Creteil, Creteil; Florian Cabillic, Université de Rennes 1, Rennes, France; Juergen Wolf and Sebastian Michels, Center for Integrated Oncology, Cologne; Georg Pall, Fachkliniken Wangen, Wangen Im Allgäu; Arne Warth, Heidelberg University Hospital; Thomas Muley, Thoraxklinik at University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany; David P. Carbone and Dwight Owen, Ohio State University Comprehensive Cancer Center, Columbus; Vamsidhar Velcheti, Cleveland Clinic, Pepper Pike, OH; Ross Camidge and Vignhesh Narayanan, University of Colorado, Denver; Robert C. Doebele, University of Colorado, Aurora, CO; Pasi A. Janne and Mark M. Awad, Dana-Farber Cancer Institute, Boston, MA; Daniel D. Karp, The University of Texas MD Anderson Cancer Center, Houston, TX; Heather A. Wakelee and Joel W. Neal, Stanford University, Stanford; Sai-Hong Ignatius Ou, University of California, Irvine, Orange; David R. Gandara and Jonathan W. Riess, University of California, Davis Cancer Center, Sacramento, CA; Alexander Drilon, Memorial Sloan Kettering Cancer Center, New York, NY; Nir Peled, Davidoff Cancer Center, Petach Tiqwa, Israël; Chul-Cho Byoung, Yonseï Cancer Center, Seoul, Republic of Korea; Michael Van Den Heuvel, Netherlands Cancer Institute, Amsterdam, the Netherlands; Tony S.K. Mok, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China; James C.H. Yang and Jin-Yuan Shih, National Taiwan University Hospital, Taipei, Republic of China; Sanjay Popat, Royal Marsden Hospital, London, United Kingdom; and Rafael Rosell and Niki Karachaliou, Catalan Institute of Oncology, Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2016.70.9352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559893PMC
May 2017

Predictive factors of early distant brain failure after gamma knife radiosurgery alone in patients with brain metastases of non-small-cell lung cancer.

J Neurooncol 2017 04 10;132(2):333-340. Epub 2017 Jan 10.

Department of Neurosurgery, Brain Research Institute, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul, South Korea.

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http://dx.doi.org/10.1007/s11060-017-2373-4DOI Listing
April 2017

Establishment of a Conditional Transgenic Mouse Model Recapitulating EML4-ALK-Positive Human Non-Small Cell Lung Cancer.

J Thorac Oncol 2017 03 9;12(3):491-500. Epub 2016 Nov 9.

Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.10.022DOI Listing
March 2017

Rare Incidence of Rearrangement in Cholangiocarcinoma.

Cancer Res Treat 2017 Jan 27;49(1):185-192. Epub 2016 Apr 27.

Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2015.497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266400PMC
January 2017

Optimal Adjuvant Treatment for Curatively Resected Thoracic Esophageal Squamous Cell Carcinoma: A Radiotherapy Perspective.

Cancer Res Treat 2017 Jan 23;49(1):168-177. Epub 2016 Jun 23.

Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2016.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266406PMC
January 2017

Clinical course of stage IV invasive mucinous adenocarcinoma of the lung.

Lung Cancer 2016 12 6;102:82-88. Epub 2016 Nov 6.

Department of Pathology, Severance Hospital, Yonsei University College of Medicine, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.11.004DOI Listing
December 2016

Efficacy and safety of dovitinib in pretreated patients with advanced squamous non-small cell lung cancer with FGFR1 amplification: A single-arm, phase 2 study.

Cancer 2016 Oct 17;122(19):3024-31. Epub 2016 Jun 17.

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1002/cncr.30135DOI Listing
October 2016

Alteration status and prognostic value of MET in head and neck squamous cell carcinoma.

J Cancer 2016 25;7(15):2197-2206. Epub 2016 Oct 25.

Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.7150/jca.16686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166528PMC
October 2016

EGFR-Mediated Reactivation of MAPK Signaling Induces Acquired Resistance to GSK2118436 in BRAF V600E-Mutant NSCLC Cell Lines.

Mol Cancer Ther 2016 07 11;15(7):1627-36. Epub 2016 May 11.

Division of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0375DOI Listing
July 2016

Clinicopathological and prognostic significance of programmed cell death ligand-1 expression in lung adenocarcinoma and its relationship with p53 status.

Lung Cancer 2016 07 3;97:73-80. Epub 2016 May 3.

Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.05.001DOI Listing
July 2016

A Case of ALK-Rearranged Adenocarcinoma with Small Cell Carcinoma-Like Transformation and Resistance to Crizotinib.

J Thorac Oncol 2016 05 29;11(5):e55-e58. Epub 2015 Dec 29.

Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2015.12.097DOI Listing
May 2016

ER2, a novel human anti-EGFR monoclonal antibody inhibit tumor activity in non-small cell lung cancer models.

Lung Cancer 2016 May 27;95:57-64. Epub 2016 Feb 27.

Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea; Division of Medical Oncology, Yonsei Cancer Center, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.02.013DOI Listing
May 2016

Induction docetaxel and S-1 followed by concomitant radiotherapy with low-dose daily cisplatin in locally advanced head and neck carcinoma.

Head Neck 2016 04 18;38 Suppl 1:E1653-9. Epub 2016 Feb 18.

Yonsei Cancer Center, Division of Medical Oncology, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1002/hed.24294DOI Listing
April 2016

Pharmacogenetic analysis of advanced non-small-cell lung cancer patients treated with first-line paclitaxel and carboplatin chemotherapy.

Pharmacogenet Genomics 2016 Mar;26(3):116-25

aDepartment of Pharmacology and Brain Korea 21 Plus Project for Medical Sciences bDepartment of Internal Medicine, Division of Medical Oncology cDepartment of Nuclear Medicine, College of Medicine, Yonsei University, Seoul dDepartment of Internal Medicine, Division of Medical Oncology, CHA University Bundang Medical Center, Seongnam eDepartment of Pharmacology and PharmacoGenomics Research Center, College of Medicine, Inje University, Busan, Korea.

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http://dx.doi.org/10.1097/FPC.0000000000000196DOI Listing
March 2016

A randomized phase II trial of ERCC1 and RRM1 mRNA expression-based chemotherapy versus docetaxel/carboplatin in advanced non-small cell lung cancer.

Cancer Chemother Pharmacol 2016 Mar 25;77(3):539-48. Epub 2016 Jan 25.

Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-Gu, Seoul, 120-752, Korea.

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http://dx.doi.org/10.1007/s00280-016-2968-zDOI Listing
March 2016

A multicenter phase II study of sorafenib in combination with erlotinib in patients with advanced non-small cell lung cancer (KCSG-0806).

Lung Cancer 2016 Mar 29;93:1-8. Epub 2015 Dec 29.

Division of Medical Oncology, Department of Internal Medicine, CHA University Bundang Medical Center, Seongnam, South Korea; Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.12.005DOI Listing
March 2016

Next-generation epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor -mutant non-small cell lung cancer.

Lung Cancer 2016 Mar 8;93:59-68. Epub 2016 Jan 8.

Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore; School of Surgery, The University of Western Australia, Perth, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.01.003DOI Listing
March 2016