Burkhard Lehner

Burkhard Lehner

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Burkhard Lehner

Burkhard Lehner

Publications by authors named "Burkhard Lehner"

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52Publications

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Optimization of the chicken chorioallantoic membrane assay as reliable in vivo model for the analysis of osteosarcoma.

PLoS One 2019 15;14(4):e0215312. Epub 2019 Apr 15.

Center for Orthopedics, Trauma Surgery and Paraplegiology, University of Heidelberg, Baden-Württemberg, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215312PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464229PMC
April 2019

Outcome of conservative and surgical treatment of enchondromas and atypical cartilaginous tumors of the long bones: retrospective analysis of 228 patients.

BMC Musculoskelet Disord 2019 Mar 28;20(1):134. Epub 2019 Mar 28.

Department of Orthopaedics, Trauma Surgery and Paraplegiology, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12891-019-2502-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440168PMC
March 2019

Riesenhafte solitäre synoviale Gelenkchondromatose, die einen malignen Tumor imitiert.

Rofo 2018 Dec 25;190(12):1163-1165. Epub 2018 Oct 25.

Pathology, Pathology Rosenheim, Germany.

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http://dx.doi.org/10.1055/a-0640-3401DOI Listing
December 2018

Surgical therapy of benign and low-grade malignant intramedullary chondroid lesions of the distal femur: intralesional resection and bone cement filling with or without osteosynthesis.

Strategies Trauma Limb Reconstr 2018 Nov 3;13(3):163-170. Epub 2018 Nov 3.

Center of Orthopaedics, Trauma Surgery and Paraplegiology, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.

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http://link.springer.com/10.1007/s11751-018-0321-2
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http://dx.doi.org/10.1007/s11751-018-0321-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249151PMC
November 2018

[Infections after reconstructive spinal interventions : How do I deal with them?]

Orthopade 2018 04;47(4):288-295

Zentrum für Orthopädie, Unfallchirurgie und Paraplegiologie, Universitätsklinikum Heidelberg, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.

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http://dx.doi.org/10.1007/s00132-018-3557-0DOI Listing
April 2018

MiR-127 and miR-376a act as tumor suppressors by in vivo targeting of COA1 and PDIA6 in giant cell tumor of bone.

Cancer Lett 2017 11 1;409:49-55. Epub 2017 Sep 1.

Research Centre for Experimental Orthopedics, Clinic for Orthopedics and Trauma Surgery, University of Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.08.029DOI Listing
November 2017

Bacterial Infection and Implant Loosening in Hip and Knee Arthroplasty: Evaluation of 209 Cases.

Materials (Basel) 2016 Oct 26;9(11). Epub 2016 Oct 26.

Center for Orthopaedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, Heidelberg 69118, Germany.

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http://dx.doi.org/10.3390/ma9110871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457256PMC
October 2016

Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma.

BMC Cancer 2016 Mar 15;16:223. Epub 2016 Mar 15.

Clinic for Orthopedics and Trauma Surgery/Spinal Cord Injury Center; Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12885-016-2266-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793522PMC
March 2016

Evaluation of implant sonication as a diagnostic tool in implant-associated infections.

J Appl Biomater Funct Mater 2014 Dec 30;12(3):135-40. Epub 2014 Dec 30.

1 Department for Orthopedics, Traumatology and Paraplegiology, University of Heidelberg, Heidelberg - Germany.

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http://journals.sagepub.com/doi/10.5301/jabfm.5000205
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http://dx.doi.org/10.5301/jabfm.5000205DOI Listing
December 2014

Osteosarcoma microenvironment: whole-slide imaging and optimized antigen detection overcome major limitations in immunohistochemical quantification.

PLoS One 2014 3;9(3):e90727. Epub 2014 Mar 3.

Department of Pediatrics, University Hospital Heidelberg, Heidelberg, Germany; Department of Translational Pulmonology, Translational Lung Research Center (TLRC), Member of the German Center for Lung, University of Heidelberg, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090727PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940945PMC
November 2014

Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour.

Histopathology 2014 Nov 2;65(5):613-22. Epub 2014 Sep 2.

Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), CCU Neuropathology German Cancer Research Centre (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1111/his.12431DOI Listing
November 2014

Epigenetic silencing of genes and microRNAs within the imprinted Dlk1-Dio3 region at human chromosome 14.32 in giant cell tumor of bone.

BMC Cancer 2014 Jul 9;14:495. Epub 2014 Jul 9.

Research Centre for Experimental Orthopedics, Department of Orthopedics, Trauma Surgery and Paraplegia, Orthopedic University Hospital Heidelberg, Schlierbacher Landstr 200a, Heidelberg 69118, Germany.

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http://dx.doi.org/10.1186/1471-2407-14-495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101709PMC
July 2014

CT-guided radiofrequency ablation of osteoid osteoma: correlation of clinical outcome and imaging features.

Diagn Interv Radiol 2013 Jul-Aug;19(4):330-9

Departments of Diagnostic and Interventional Radiology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.5152/dir.2013.096DOI Listing
May 2014

A persistent case of tuberculosis of the pubic symphysis and pubic bone.

BMJ Case Rep 2014 Mar 10;2014. Epub 2014 Mar 10.

Department of Orthopaedics and Trauma Surgery, Heidelberg University, Heidelberg, Germany.

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http://casereports.bmj.com/cgi/doi/10.1136/bcr-2013-203456
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http://dx.doi.org/10.1136/bcr-2013-203456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962947PMC
March 2014

On the inflammatory response in metal-on-metal implants.

J Transl Med 2014 Mar 21;12:74. Epub 2014 Mar 21.

Department of Orthopaedics and Trauma Surgery, University Hospital Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1479-5876-12-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994416PMC
March 2014

Negative-pressure wound therapy with instillation: international consensus guidelines.

Plast Reconstr Surg 2013 Dec;132(6):1569-79

Washington, D.C.; Heidelberg and Berlin, Germany; Dallas, Texas; Scottsdale, Ariz.; Boston, Mass.; Chicago, Ill.; New York, N.Y.; Vancouver, Wash.; Gainesville, Fla. From the Department of Plastic Surgery, Georgetown University Hospital; the Orthopedic and Trauma Clinic, Heidelberg University; Department of Trauma Senior Surgery and Orthopedics, Reconstructive, Septic, and Hand Surgery, Military Hospital Berlin; the Department of Plastic Surgery, University of Texas Southwestern; the Division of General Surgery, Scottsdale Healthcare Osborn Medical Center; the Department of Surgery, Harvard Medical School; the Department of Clinical Surgery, University of Illinois at Chicago; the Department of Surgery, Columbia University; the Department of Plastic and Maxillofacial Surgery, Southwest Washington Medical Center; and the Department of Wound Research, University of Florida.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PRS.0b013e3182a80586DOI Listing
December 2013

Rescue of silenced UCHL1 and IGFBP4 expression suppresses clonogenicity of giant cell tumor-derived stromal cells.

Cancer Lett 2013 Aug 18;336(1):61-7. Epub 2013 Apr 18.

Orthopedic University Hospital Heidelberg, Department of Experimental Orthopedics, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.canlet.2013.04.011DOI Listing
August 2013

Haematogenous infection of a total knee arthroplasty with Klebsiella pneumoniae.

BMJ Case Rep 2013 Apr 15;2013. Epub 2013 Apr 15.

Department of Orthopaedics and Trauma Surgery, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1136/bcr-2013-008588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645236PMC
April 2013

CT-guided radiofrequency ablation of osteoid osteoma and osteoblastoma: clinical success and long-term follow up in 77 patients.

Eur J Radiol 2012 Nov 6;81(11):3426-34. Epub 2012 Jul 6.

Department of Diagnostic and Interventional Radiology, University of Heidelberg, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejrad.2012.04.037DOI Listing
November 2012

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors.

BMC Cancer 2012 Oct 22;12:488. Epub 2012 Oct 22.

Research Centre for Experimental Orthopaedics, Department of Orthopaedics, Trauma Surgery and Paraplegiology, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, 69118, Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2407-12-488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495847PMC
October 2012

A microRNA signature differentiates between giant cell tumor derived neoplastic stromal cells and mesenchymal stem cells.

Cancer Lett 2012 Aug 7;321(2):162-8. Epub 2012 Feb 7.

Research Centre for Experimental Orthopedics, Department of Orthopedics, Trauma Surgery and Paraplegia, Orthopedic University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.canlet.2012.01.043DOI Listing
August 2012

Use of negative pressure wound therapy over clean, closed surgical incisions.

Int Wound J 2012 Aug;9 Suppl 1:32-9

Department of Orthopedic Surgery, University of Missouri School of Medicine, Columbia, MO, USA.

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http://dx.doi.org/10.1111/j.1742-481X.2012.01017.xDOI Listing
August 2012

Mid- and long-term clinical results of surgical therapy in unicameral bone cysts.

BMC Musculoskelet Disord 2011 Dec 13;12:281. Epub 2011 Dec 13.

Department of Orthopedic Surgery and Traumatology, University Hospital of Heidelberg, Schlierbacher Landstrasse 200a, 69115 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2474-12-281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258224PMC
December 2011

First experiences with negative pressure wound therapy and instillation in the treatment of infected orthopaedic implants: a clinical observational study.

Int Orthop 2011 Sep 17;35(9):1415-20. Epub 2011 May 17.

Department of Orthopedic Oncology and Septic Orthopedic Surgery, Orthopedic University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00264-011-1274-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167463PMC
September 2011

Clinical and radiological long-term results after operative treatment of chondroblastoma.

Arch Orthop Trauma Surg 2011 Jan 3;131(1):45-52. Epub 2010 Apr 3.

Division of Orthopedic Oncology and Septic Surgery, Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00402-010-1099-yDOI Listing
January 2011

The impact of pathological fractures on therapy outcome in patients with primary malignant bone tumours.

Int Orthop 2010 Oct 13;34(7):1017-23. Epub 2009 Dec 13.

Orthopaedic Clinic, University of Heidelberg, Schlierbacher Landstrasse 200a, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00264-009-0921-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989037PMC
October 2010

Silencing of the UCHL1 gene in giant cell tumors of bone.

Int J Cancer 2010 Oct;127(8):1804-12

Department of Experimental Orthopaedics, Orthopaedic University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.25205DOI Listing
October 2010

Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours.

Histopathology 2010 Apr;56(5):641-51

Orthopaedic University Hospital of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1365-2559.2010.03528.xDOI Listing
April 2010

Intraoperative electron radiotherapy for the management of aggressive fibromatosis.

Int J Radiat Oncol Biol Phys 2010 Mar 3;76(4):1154-60. Epub 2009 Aug 3.

Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2009.03.067DOI Listing
March 2010

Genomic profiling reveals subsets of dedifferentiated liposarcoma to follow separate molecular pathways.

Virchows Arch 2010 Mar 29;456(3):277-85. Epub 2009 Dec 29.

Institute of Pathology, University Hospital, INF 220/221, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00428-009-0869-9DOI Listing
March 2010

Trochanteric fractures in the elderly: the influence of primary hip arthroplasty on 1-year mortality.

Arch Orthop Trauma Surg 2007 Dec;127(10):959-66

Orthopaedic University Hospital, Schlierbacher Landstr 200a, 69118, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00402-007-0423-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111040PMC
December 2007

Intraarticular lesions in primary frozen shoulder after manipulation under general anesthesia.

J Shoulder Elbow Surg 2005 Jan-Feb;14(1):16-21

Department of Shoulder and Elbow Surgery, University Hospital for Orthopaedic Surgery, Heidelberg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S105827460400135
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http://dx.doi.org/10.1016/j.jse.2004.04.004DOI Listing
May 2005

Shoulder arthroplasty in nontraumatic osteonecrosis of the humeral head.

J Shoulder Elbow Surg 2003 May-Jun;12(3):226-30

Department of Orthopaedic Surgery, University Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/mse.2003.S105827460200040XDOI Listing
October 2003