Burkhard Brandt

Burkhard Brandt

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Burkhard Brandt

Burkhard Brandt

Publications by authors named "Burkhard Brandt"

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Low Numbers of Vascular Vessels Correlate to Progression in Hormone-Naïve Prostate Carcinomas Undergoing Radical Prostatectomy.

Cancers (Basel) 2019 Sep 12;11(9). Epub 2019 Sep 12.

Laboratory of Cell Biology, Department of Medical Biotechnology, Medical University of Gdańsk, Gdańsk 80-211, Poland.

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http://dx.doi.org/10.3390/cancers11091356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770894PMC
September 2019

BRCAness in prostate cancer.

Oncotarget 2019 Mar 29;10(25):2421-2422. Epub 2019 Mar 29.

Natalia Bednarz-Knoll: Laboratory of Cell Biology, Department of Medical Biotechnology, Medical University of Gdańsk, Gdańsk, Poland.

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http://dx.doi.org/10.18632/oncotarget.26818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497433PMC
March 2019

Somatic aberrations of BRCA1 gene are associated with ALDH1, EGFR, and tumor progression in prostate cancer.

Int J Cancer 2019 02 22;144(3):607-614. Epub 2018 Oct 22.

Institute of Tumour Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/ijc.31905DOI Listing
February 2019

ALDH1-positive intratumoral stromal cells indicate differentiated epithelial-like phenotype and good prognosis in prostate cancer.

Transl Res 2019 01 12;203:49-56. Epub 2018 Sep 12.

Department of Tumour Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Laboratory of Cell Biology, Department of Medical Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Gdańsk, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19315244183014
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http://dx.doi.org/10.1016/j.trsl.2018.08.007DOI Listing
January 2019

Exploring prostate cancer genome reveals simultaneous losses of PTEN, FAS and PAPSS2 in patients with PSA recurrence after radical prostatectomy.

Int J Mol Sci 2015 Feb 11;16(2):3856-69. Epub 2015 Feb 11.

Prostate Center, Department of Urology, University Hospital Muenster, Albert-Schweitzer-Campus 1, Gebaeude 1A, Muenster D-48149, Germany.

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http://dx.doi.org/10.3390/ijms16023856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346930PMC
February 2015

AKT3 regulates ErbB2, ErbB3 and estrogen receptor α expression and contributes to endocrine therapy resistance of ErbB2(+) breast tumor cells from Balb-neuT mice.

Cell Signal 2014 May 24;26(5):1021-9. Epub 2014 Jan 24.

Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.01.018DOI Listing
May 2014

EGFR intron-1 CA repeat polymorphism is a predictor of relapse and survival in complete resected only surgically treated esophageal cancer.

Target Oncol 2014 Mar 2;9(1):43-52. Epub 2013 Feb 2.

Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Martini Strasse 52, 20246, Hamburg, Germany,

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http://dx.doi.org/10.1007/s11523-013-0260-2DOI Listing
March 2014

Genome-wide investigation of multifocal and unifocal prostate cancer-are they genetically different?

Int J Mol Sci 2013 Jun 3;14(6):11816-29. Epub 2013 Jun 3.

Prostate Center, Department of Urology, University Hospital Muenster, Albert-Schweitzer-Campus 1, Gebaeude 1A, Muenster D-48149, Germany.

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http://www.mdpi.com/1422-0067/14/6/11816
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http://dx.doi.org/10.3390/ijms140611816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709757PMC
June 2013

Systematic analysis of in vitro chemosensitivity and mib-1 expression in molecular breast cancer subtypes.

Eur J Cancer 2012 Sep 13;48(13):2066-74. Epub 2011 Sep 13.

Department of Gynecology and Obstetrics, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1016/j.ejca.2011.08.006DOI Listing
September 2012

The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination.

J Pathol 2012 Jun 21;227(2):234-44. Epub 2012 Mar 21.

Institute of Immunology, Witten/Herdecke University, Germany.

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http://dx.doi.org/10.1002/path.3991DOI Listing
June 2012

Hybrid cells derived from breast epithelial cell/breast cancer cell fusion events show a differential RAF-AKT crosstalk.

Cell Commun Signal 2012 Apr 9;10(1):10. Epub 2012 Apr 9.

Zentrum für Biomedizinische Ausbildung und Forschung der UWH (ZBAF), Institute of Immunology, Witten/Herdecke University, Stockumer Str, 10, 58448 Witten, Germany.

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http://dx.doi.org/10.1186/1478-811X-10-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349602PMC
April 2012

Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells.

Cell Signal 2011 Dec 12;23(12):1952-60. Epub 2011 Jul 12.

Institute of Biochemistry and Signal Transduction, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S08986568110020
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http://dx.doi.org/10.1016/j.cellsig.2011.07.003DOI Listing
December 2011

Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification.

Int J Radiat Oncol Biol Phys 2011 Jul 20;80(4):1181-8. Epub 2011 Apr 20.

Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hubertus Wald Tumor Center, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2011.02.043DOI Listing
July 2011

Detection and clinical relevance of early disseminated breast cancer cells depend on their cytokeratin expression pattern.

Breast Cancer Res Treat 2011 Feb 7;125(3):729-38. Epub 2010 May 7.

Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s10549-010-0911-2DOI Listing
February 2011

Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells.

Clin Exp Metastasis 2011 Jan 28;28(1):75-90. Epub 2010 Oct 28.

Institute of Immunology, Zentrum für Biomedizinische Ausbildung und Forschung an der UWH (ZBAF), Witten/Herdecke University, Stockumer Str. 10, 58448 Witten, Germany.

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http://link.springer.com/content/pdf/10.1007/s10585-010-9359
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http://link.springer.com/10.1007/s10585-010-9359-3
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http://dx.doi.org/10.1007/s10585-010-9359-3DOI Listing
January 2011

Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.

J Proteome Res 2010 Jun;9(6):3158-68

Institute for Tumor Biology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, Germany.

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http://dx.doi.org/10.1021/pr100039dDOI Listing
June 2010

Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.

J Biol Chem 2010 Feb 17;285(8):5541-54. Epub 2009 Dec 17.

Institut für Biochemie und Molekularbiologie I, Zelluläre Signaltransduktion, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.

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http://dx.doi.org/10.1074/jbc.M109.047050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820782PMC
February 2010

Molecular targeted therapies for breast cancer treatment.

Breast Cancer Res 2008 24;10(4):211. Epub 2008 Jul 24.

Department of Obstetrics and Gynecology, Breast Centre Klinikum Lüdenscheid, Academic Teaching Hospital of the University Bonn, Luedenscheid, Paulmannshoeher Str, 14 - 58515 Luedenscheid Germany.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr2112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575526PMC
April 2009

Detection, clinical relevance and specific biological properties of disseminating tumour cells.

Nat Rev Cancer 2008 May;8(5):329-40

Institute of Tumour Biology, Center of Experimental Medicine, University Medical Center Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany.

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http://dx.doi.org/10.1038/nrc2375DOI Listing
May 2008

Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.

Oncol Rep 2007 Sep;18(3):639-43

Department of Cranio-Maxillofacial Surgery, University of Münster, Germany.

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September 2007

Cell cycle regulating proteins p21 and p27 in prognosis of oral squamous cell carcinomas.

Oncol Rep 2007 Feb;17(2):355-9

Department of Cranio-Maxillofacial Surgery, University of Münster, D-48129 Münster, and Central Army Hospital Koblenz, Germany.

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February 2007

Mechanisms of egfr gene transcription modulation: relationship to cancer risk and therapy response.

Clin Cancer Res 2006 Dec;12(24):7252-60

Institute for Tumor Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0626DOI Listing
December 2006

(CA)n microsatellite polymorphism of ERBB-1 in breast cancer.

Eur J Cancer 2006 Aug 12;42(12):1698-701. Epub 2006 Jun 12.

Department of Oncology and Radiotherapy, Medical University of Gdańsk, ul. Debinki 7, 80-211 Gdańsk, Poland.

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http://dx.doi.org/10.1016/j.ejca.2006.03.012DOI Listing
August 2006

Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies.

Biochim Biophys Acta 2006 Aug 9;1766(1):42-52. Epub 2006 May 9.

Department of Haematology-Oncology, University Hospital, Westf.-Wilhelms-Univ. Münster, Germany.

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http://dx.doi.org/10.1016/j.bbcan.2006.04.001DOI Listing
August 2006

Options for visualizing metastatic disease in the living body.

Contrib Microbiol 2006 ;13:209-231

Institute of Pathology, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1159/000092975DOI Listing
July 2006

HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients.

Clin Cancer Res 2006 Mar;12(6):1715-20

Department of Obstetrics and Gynecology, Gerhard-Domagk Institute of Pathology, and Institute of Clinical Chemistry and Laboratory Medicine, University of Münster, Münster, Germany.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-05-2087DOI Listing
March 2006

3D-extravasation model -- selection of highly motile and metastatic cancer cells.

Semin Cancer Biol 2005 Oct;15(5):387-95

Institute of Tumor Biology, Center of Experimental Medicine, University Medical Center, Hamburg-Eppendorf, Martinistr. 52, 20146 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2005.06.006DOI Listing
October 2005

Effectiveness of hydroxyapatite-vancomycin bone cement in the treatment of Staphylococcus aureus induced chronic osteomyelitis.

Biomaterials 2005 Sep;26(25):5251-8

Department of Trauma and Orthopaedic Surgery, Munarienhospital Osnabrück, Johannisfreiheit 2-4, 49074 Osnabrück Germany.

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http://dx.doi.org/10.1016/j.biomaterials.2005.01.001DOI Listing
September 2005

First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer.

J Pathol 2005 Jul;206(3):366-76

Institute of Clinical Chemistry and Laboratory Medicine, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1002/path.1785DOI Listing
July 2005

HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor.

BMC Cancer 2005 Jul 21;5:84. Epub 2005 Jul 21.

Department of Cranio-Maxillofacial Surgery, University of Münster, Waldeyerstrasse 30, 48129 Münster, Germany.

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http://dx.doi.org/10.1186/1471-2407-5-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190162PMC
July 2005

Modified direct-double-differential PCR for gene dosage quantification of HER2.

Oncol Rep 2005 May;13(5):971-5

Molecular Diagnostics Division, Department of Biotechnology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Kladki 24, 80-822 Gdansk, Poland.

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May 2005

Modification of breast cancer risk in young women by a polymorphic sequence in the egfr gene.

Cancer Res 2004 Jan;64(1):7-12

Institute for Clinical Chemistry and Laboratory Medicine, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1158/0008-5472.can-03-2623DOI Listing
January 2004

Molecular diagnostics of solid malignant tumours.

Clin Lab 2002 ;48(11-12):605-15

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July 2003

Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development.

Cancer Res 2003 Mar;63(6):1172-8

Institute of Clinical Chemistry and Laboratory Medicine, University of Münster, 48149 Münster, Germany.

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March 2003

Combining free and total prostate specific antigen assays from different manufacturers: the pitfalls.

Eur Urol 2002 Dec;42(6):577-82; discussion 582

Department of Urology, University of Münster, Albert-Schweitzer Str. 33, D-48129 Münster, Germany.

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http://dx.doi.org/10.1016/s0302-2838(02)00449-9DOI Listing
December 2002

Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR.

FASEB J 2002 Nov 19;16(13):1823-5. Epub 2002 Sep 19.

Institute of Immunology, University of Witten/Herdecke, Stockumer Str. 10, 58448 Witten, Germany.

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http://dx.doi.org/10.1096/fj.02-0096fjeDOI Listing
November 2002

Migrating and circulating breast carcinoma cells are within active phases of the cell cycle.

Anticancer Res 2002 Mar-Apr;22(2A):899-903

Institute of Immunology, University Witten/Herdecke, Witten, Germany.

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June 2002

Trimodality treatment in Stage III nonsmall cell lung carcinoma: prrognostic impact of K-ras mutations after neoadjuvant therapy.

Cancer 2002 Apr;94(7):2055-62

Department of Medicine/Hematologic and Oncology and Respiratory Medicine, University of Muenster, Albert-Schweitzer-Strasse 33, 48129 Muenster, Germany.

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http://dx.doi.org/10.1002/cncr.10387DOI Listing
April 2002

Early placenta insulin-like growth factor (pro-EPIL) is overexpressed and secreted by c-erbB-2-positive cells with high invasion potential.

Cancer Res 2002 Feb;62(4):1020-4

Institute for Clinical Chemistry and Laboratory Medicine, Westfälische Wilhelms-Universität Münster, Germany 48149.

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February 2002

Cancer cell motility--on the road from c-erbB-2 receptor steered signaling to actin reorganization.

Exp Cell Res 2002 Jan;272(2):93-108

Institut für Klinische Chemie und Laboratoriumsmedizin, Westfälische Wilhelms-Universität, Münster, Albert-Schweitzer-Strasse 33, Münster, 48149, Germany.

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http://dx.doi.org/10.1006/excr.2001.5385DOI Listing
January 2002