Publications by authors named "Burkhard Becher"

100Publications

Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.

Immunity 2020 Nov;53(5):1015-1032.e8

Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany; Berlin Institute of Health (BIH), Anna-Louisa-Karsch Strasse 2, 10117 Berlin, Germany; Mucosal and Developmental Immunology, Deutsches Rheuma-Forschungszentrum (DRFZ), an institute of the Leibniz Association, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.10.012DOI Listing
November 2020

The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development.

Cell Rep 2020 Jun;31(13):107826

Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107826DOI Listing
June 2020

GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches.

Nat Rev Immunol 2020 08 23;20(8):507-514. Epub 2020 Jun 23.

Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/s41577-020-0357-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309428PMC
August 2020

CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.

Autophagy 2020 May 13:1-15. Epub 2020 May 13.

Department of Neurology with Institute of Translational Neurology, University of Münster , Münster, Germany.

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http://dx.doi.org/10.1080/15548627.2020.1756678DOI Listing
May 2020

Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells.

Leukemia 2020 10 1;34(10):2688-2703. Epub 2020 May 1.

Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Comprehensive Cancer Center Zurich (CCCZ), Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41375-020-0818-9DOI Listing
October 2020

Skipping adolescence to become super-inflammatory monocytes.

Nat Immunol 2020 05;21(5):491-492

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41590-020-0652-2DOI Listing
May 2020

Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.

J Exp Med 2020 04;217(4)

Department of Anatomy and Cell Biology, Stark Neuroscience Research Institute, School of Medicine, Indiana University, Indianapolis, IN.

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http://dx.doi.org/10.1084/jem.20191374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144522PMC
April 2020

Extracorporeal Photopheresis for Colitis Induced by Checkpoint-Inhibitor Therapy.

N Engl J Med 2020 01;382(3):294-296

University Medical Center Freiburg, Freiburg, Germany

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http://dx.doi.org/10.1056/NEJMc1912274DOI Listing
January 2020

Glial Cells as Regulators of Neuroimmune Interactions in the Central Nervous System.

J Immunol 2020 01;204(2):251-255

Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115; and.

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http://dx.doi.org/10.4049/jimmunol.1900908DOI Listing
January 2020

Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective.

J Exp Med 2020 01;217(1)

Institute of Experimental Immunology, Department of Inflammation Research, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1084/jem.20191123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037236PMC
January 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation.

Proc Natl Acad Sci U S A 2019 10 23;116(41):20635-20643. Epub 2019 Sep 23.

The Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1905762116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789640PMC
October 2019

The CNS Immune Landscape from the Viewpoint of a T Cell.

Trends Neurosci 2019 10 29;42(10):667-679. Epub 2019 Aug 29.

Experimental Immunology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2019.07.008DOI Listing
October 2019

Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry.

Nat Protoc 2019 07 3;14(7):1946-1969. Epub 2019 Jun 3.

Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy.

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http://dx.doi.org/10.1038/s41596-019-0166-2DOI Listing
July 2019

Innate lymphoid cells as regulators of the tumor microenvironment.

Semin Immunol 2019 02 11;41:101270. Epub 2019 Mar 11.

Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.smim.2019.03.002DOI Listing
February 2019

Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8 T Cells.

Cancer Immunol Res 2019 04 19;7(4):572-583. Epub 2019 Feb 19.

Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH Zurich), Zurich, Switzerland.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978143PMC
April 2019

ARTD1 in Myeloid Cells Controls the IL-12/18-IFN-γ Axis in a Model of Sterile Sepsis, Chronic Bacterial Infection, and Cancer.

J Immunol 2019 03 23;202(5):1406-1416. Epub 2019 Jan 23.

Department of Molecular Mechanisms of Disease, University of Zurich, 8057 Zurich, Switzerland;

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http://dx.doi.org/10.4049/jimmunol.1801107DOI Listing
March 2019

The end of omics? High dimensional single cell analysis in precision medicine.

Eur J Immunol 2019 02 25;49(2):212-220. Epub 2019 Jan 25.

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/eji.201847758DOI Listing
February 2019

Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation.

Cell Rep 2018 12;25(13):3564-3572.e4

Institute of Experimental Immunology, Department of Inflammation Research, University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183192
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http://dx.doi.org/10.1016/j.celrep.2018.12.012DOI Listing
December 2018

T cells in patients with narcolepsy target self-antigens of hypocretin neurons.

Nature 2018 10 19;562(7725):63-68. Epub 2018 Sep 19.

Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera italiana, Bellinzona, Switzerland.

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http://dx.doi.org/10.1038/s41586-018-0540-1DOI Listing
October 2018

Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes.

J Allergy Clin Immunol 2019 01 14;143(1):292-304.e8. Epub 2018 Jun 14.

Division of Immunology, University Children's Hospital Zurich, Zurich, Switzerland; Pediatric Immunology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.02.057DOI Listing
January 2019

Conditional Gene-Targeting in Mice: Problems and Solutions.

Immunity 2018 05;48(5):835-836

Division of Biological Sciences, Center for Microbiome Innovation and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.immuni.2018.05.002DOI Listing
May 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4 T cell pathogenicity during CNS inflammation.

Proc Natl Acad Sci U S A 2017 12 12;114(52):E11228-E11237. Epub 2017 Dec 12.

Institute of Experimental Immunology, Laboratory of Neuroinflammation, University of Zurich, 8057 Zurich, Switzerland;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1713664114
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http://dx.doi.org/10.1073/pnas.1713664114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748192PMC
December 2017

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression.

Sci Rep 2017 11 29;7(1):16547. Epub 2017 Nov 29.

Clinical Neuroimmunology Unit, Department of Neuroscience, Institute for Experimental Neurology, San Raffaele Scientific Institute, 20132, Milan, Italy.

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http://dx.doi.org/10.1038/s41598-017-16702-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707351PMC
November 2017

The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages.

Immunity 2017 11 7;47(5):903-912.e4. Epub 2017 Nov 7.

Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.10.007DOI Listing
November 2017

Restoration of Natural Killer Cell Antimetastatic Activity by IL12 and Checkpoint Blockade.

Cancer Res 2017 12 17;77(24):7059-7071. Epub 2017 Oct 17.

Inflammation research, Institute of Experimental Immunology, University of Zurich, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1032DOI Listing
December 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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http://doi.wiley.com/10.1002/eji.201646632
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http://dx.doi.org/10.1002/eji.201646632DOI Listing
October 2017

Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System.

Immunity 2017 02;46(2):245-260

Institute of Experimental Immunology, Inflammation Research, University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.01.007DOI Listing
February 2017

High Dimensional Cytometry of Central Nervous System Leukocytes During Neuroinflammation.

Methods Mol Biol 2017 ;1559:321-332

Institute of Experimental Immunology, University of Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-6786-5_22DOI Listing
January 2018

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.

Nat Commun 2016 12 16;7:13708. Epub 2016 Dec 16.

Inflammation Research, Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1038/ncomms13708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172358PMC
December 2016

Cytokine networks in neuroinflammation.

Nat Rev Immunol 2017 01 5;17(1):49-59. Epub 2016 Dec 5.

Department of Immunology, University of Washington, Seattle, Washington 98109-8059, USA.

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http://www.nature.com/articles/nri.2016.123
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http://dx.doi.org/10.1038/nri.2016.123DOI Listing
January 2017

GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation.

Immunity 2016 11;45(5):963-973

Institute of Experimental Immunology, University of Zurich Winterthurerstrasse 190, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.immuni.2016.10.026DOI Listing
November 2016

Sall1 is a transcriptional regulator defining microglia identity and function.

Nat Immunol 2016 Dec 24;17(12):1397-1406. Epub 2016 Oct 24.

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/ni.3585DOI Listing
December 2016

BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis.

J Exp Med 2016 07 18;213(8):1537-53. Epub 2016 Jul 18.

Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska Hospital at Solna, S-171 76 Stockholm, Sweden

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http://dx.doi.org/10.1084/jem.20150577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986521PMC
July 2016

T cell-specific inactivation of mouse CD2 by CRISPR/Cas9.

Sci Rep 2016 Feb 23;6:21377. Epub 2016 Feb 23.

Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Germany.

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http://dx.doi.org/10.1038/srep21377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763270PMC
February 2016

Contemplating autoimmunity in the Aegean islands.

Nat Immunol 2016 Mar;17(3):218-20

Institute of Experimental Immunology, Inflammation Research Unit, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/ni.3367DOI Listing
March 2016

The Good, the Bad, or the Pretty: IL-17 Builds Lymphoid Tissues in the Brain.

Authors:
Burkhard Becher

Immunity 2015 Dec;43(6):1033-4

Institute of Experimental Immunology, Inflammation Research, University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.11.021DOI Listing
December 2015

IL17A-Mediated Endothelial Breach Promotes Metastasis Formation.

Cancer Immunol Res 2016 Jan 19;4(1):26-32. Epub 2015 Nov 19.

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0154DOI Listing
January 2016

The end of gating? An introduction to automated analysis of high dimensional cytometry data.

Eur J Immunol 2016 Jan 30;46(1):34-43. Epub 2015 Nov 30.

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/eji.201545774DOI Listing
January 2016

Perspectives on cytokine-directed therapies in multiple sclerosis.

Swiss Med Wkly 2015 23;145:w14199. Epub 2015 Oct 23.

Institute of Experimental Immunology, University of Zurich, Switzerland.

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http://dx.doi.org/10.4414/smw.2015.14199DOI Listing
June 2016

GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage.

Trends Immunol 2015 Oct;36(10):651-662

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.it.2015.08.004DOI Listing
October 2015

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.

Immunity 2015 Sep 1;43(3):502-14. Epub 2015 Sep 1.

Institute of Experimental Immunology, University of Zürich, Zürich 8057, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.08.010DOI Listing
September 2015

Dermal IL-17-producing γδ T cells establish long-lived memory in the skin.

Eur J Immunol 2015 Nov 19;45(11):3022-33. Epub 2015 Oct 19.

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/eji.201545883DOI Listing
November 2015

Rational Combination of Immunotherapies with Clinical Efficacy in Mice with Advanced Cancer.

Cancer Immunol Res 2015 Nov 3;3(11):1279-88. Epub 2015 Jul 3.

Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0103-TDOI Listing
November 2015

Programming Hippocampal Neural Stem/Progenitor Cells into Oligodendrocytes Enhances Remyelination in the Adult Brain after Injury.

Cell Rep 2015 Jun 11;11(11):1679-85. Epub 2015 Jun 11.

Brain Research Institute, Faculty of Medicine and Science, University of Zurich, 8057 Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.024DOI Listing
June 2015

Immune attack: the role of inflammation in Alzheimer disease.

Nat Rev Neurosci 2015 Jun;16(6):358-72

Institute of Experimental Immunology, University of Zürich, Winterthurerstrasse 190, CH-8057 Zrich, Switzerland.

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http://dx.doi.org/10.1038/nrn3880DOI Listing
June 2015

Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage.

J Neuroinflammation 2015 Apr 2;12:62. Epub 2015 Apr 2.

Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, Zürich, 8057, Switzerland.

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http://dx.doi.org/10.1186/s12974-015-0271-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404661PMC
April 2015

Neutralization of colony-stimulating factor 1 receptor prevents sickness behavior syndrome by reprogramming inflammatory monocytes to produce IL-10.

Brain Behav Immun 2015 Aug 4;48:78-85. Epub 2015 Mar 4.

Institute of Experimental Immunology, University of Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.02.027DOI Listing
August 2015

Helicobacter pylori-specific protection against inflammatory bowel disease requires the NLRP3 inflammasome and IL-18.

Inflamm Bowel Dis 2015 Apr;21(4):854-61

*Institutes of Molecular Cancer Research, University of Zürich, Zürich, Switzerland; ‡Experimental Immunology, University of Zürich, Zürich, Switzerland; and †Division of Gastroenterology and Hepatology, University Hospital of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1097/MIB.0000000000000318DOI Listing
April 2015

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex.

Nat Commun 2014 Nov 26;5:5611. Epub 2014 Nov 26.

Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, 20132 Milan, Italy.

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http://dx.doi.org/10.1038/ncomms6611DOI Listing
November 2014

High-dimensional analysis of the murine myeloid cell system.

Nat Immunol 2014 Dec 12;15(12):1181-9. Epub 2014 Oct 12.

Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network (SIgN), Singapore.

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http://dx.doi.org/10.1038/ni.3006DOI Listing
December 2014

T-helper cells: methods and protocols. Preface.

Methods Mol Biol 2014 ;1193:v-vi

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April 2015

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.

Nat Commun 2014 Oct 3;5:5056. Epub 2014 Oct 3.

Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, Zurich 8052, Switzerland.

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http://dx.doi.org/10.1038/ncomms6056DOI Listing
October 2014

Innate lymphoid cells regulate intestinal epithelial cell glycosylation.

Science 2014 Sep 21;345(6202):1254009. Epub 2014 Aug 21.

Division of Mucosal Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan. Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan. Division of Mucosal Immunology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1126/science.1254009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774895PMC
September 2014

IL-12-and IL-23 in health and disease.

Cytokine Growth Factor Rev 2014 Aug 1;25(4):415-21. Epub 2014 Aug 1.

Institute of Experimental Immunology, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.cytogfr.2014.07.017DOI Listing
August 2014

Disease control in cutaneous leishmaniasis is independent of IL-22.

J Invest Dermatol 2015 Jan 7;135(1):308-311. Epub 2014 Jul 7.

Department of Dermatology, University Medical Center, Johannes Gutenberg-University, Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.282DOI Listing
January 2015