Buelent Kocer

Buelent Kocer

UNVERIFIED PROFILE

Are you Buelent Kocer?   Register this Author

Register author
Buelent Kocer

Buelent Kocer

Publications by authors named "Buelent Kocer"

Are you Buelent Kocer?   Register this Author

6Publications

386Reads

28Profile Views

Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis.

J Med Chem 2015 Jan 16;58(1):512-6. Epub 2014 Apr 16.

pRED, Pharma Research & Early Development, Small Molecule Research, Discovery Chemistry, Hoffmann-La Roche Inc. , 3431 Hillview Avenue, Palo Alto, California 94304, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm500305pDOI Listing
January 2015

Finding the perfect spot for fluorine: improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold.

Bioorg Med Chem Lett 2015 Jan 20;25(2):367-71. Epub 2014 Nov 20.

Hoffmann-La Roche Inc., pRED, Pharma Research & Early Development, Small Molecule Research, Discovery Chemistry, 3431 Hillview Ave, Palo Alto, CA 94304, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2014.11.030DOI Listing
January 2015