Bryan T Hennessy

Bryan T Hennessy

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Bryan T Hennessy

Publications by authors named "Bryan T Hennessy"

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Combined Targeted Resequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for Poly(ADP-Ribose) Polymerase 1 Inhibitor Sensitivity Testing.

J Mol Diagn 2019 Mar 19;21(2):198-213. Epub 2018 Dec 19.

Department of Translational Epigenetics and Tumor Genetics, University Hospital Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University Hospital Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2018.10.007DOI Listing
March 2019

Dynamic platelet function is markedly different in patients with cancer compared to healthy donors.

Platelets 2019 25;30(6):737-742. Epub 2018 Sep 25.

a Molecular and Cellular Therapeutics , The Royal College of Surgeons in Ireland , Dublin , Ireland.

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http://dx.doi.org/10.1080/09537104.2018.1513475DOI Listing
September 2018

Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data.

J Clin Oncol 2018 04 22;36(10):981-990. Epub 2018 Feb 22.

Dimitrios Zardavas and Debora Fumagalli, Breast International Group; Christos Sotiriou, Université Libre de Bruxelles, Brussels, Belgium; Luc te Marvelde and Roger L. Milne, Cancer Council; Roger L. Milne and Sherene Loi, University of Melbourne, Melbourne; Barry Iacopetta, University of Western Australia, Western Australia; Sandra O'Toole and Elena Lopez-Knowles, Garvan Institute of Medical Research, Darlinghurst, Australia; George Fountzilas and Vassiliki Kotoula, Hellenic Foundation for Cancer Research/Aristotle University of Thessaloniki, Thessaloniki; Evangelia Razis, Hygeia Hospital; George Papaxoinis, Hippokration Hospital, Athens, Greece; Heikki Joensuu, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Mary Ellen Moynahan, Memorial Sloan Kettering Cancer Center, New York, NY; Bryan T. Hennessy, Beaumont Hospital and Royal College of Surgeons, Dublin, Ireland; Ivan Bieche, Curie Institut, Paris; Thomas Bachelot, Centre de Recherche en Cancérologie de Lyon, Lyon; Stefan Michiels, Gustave Roussy and Inserm, Univ. Paris-Sud, Univ. Paris-Saclay, Villejuif, France; Lao H. Saal, Lund University, Lund; Olle Stal, Qing Wang, and Gizeh Perez-Tenorio, Linköping University, Linköping, Sweden; Jeanette Dupont Jensen, University of Southern Denmark, on behalf of the Danish Breast Cancer Cooperative Group, Odense, Denmark; Elena Lopez-Knowles, Royal Marsden NHS Trust and Institute of Cancer Research, London; Daniel W. Rea, University of Birmingham, Birmingham, United Kingdom; Mattia Barbaraeschi, Santa Chiara Hospital, Trento, Italy; Shinzaburo Noguchi, Osaka University, Osaka Japan; Hatem A. Azim Jr, American University of Beirut (AUB), Beirut, Lebanon; Enrique Lerma, Universitat Autònoma de Barcelona, Barcelona, Spain; Cornelis J.H. can de Velde, Leiden University Medical Center, Leiden, the Netherlands; Vicky Sabine, University of Guelph, Guelph; John M.S. Bartlett, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2017.74.8301DOI Listing
April 2018

Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro.

BMC Cancer 2018 02 9;18(1):168. Epub 2018 Feb 9.

Department of Medical Oncology, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/s12885-018-4035-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807759PMC
February 2018

PI3K inhibition to overcome endocrine resistance in breast cancer.

Expert Opin Investig Drugs 2018 01 6;27(1):1-15. Epub 2018 Jan 6.

a Department of Medical Oncology , Cancer Clinical Trials and Research Unit, Beaumont Hospital , Dublin , Ireland.

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http://dx.doi.org/10.1080/13543784.2018.1417384DOI Listing
January 2018

Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers.

Ther Adv Med Oncol 2018 9;10:1758834017746040. Epub 2018 Jan 9.

Medical Oncology Group, Department of Molecular Medicine, Royal College of Surgeons in Ireland, ERC Smurfit Building, Dublin, 9, Ireland.

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http://dx.doi.org/10.1177/1758834017746040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784557PMC
January 2018

S100β as a serum marker in endocrine resistant breast cancer.

BMC Med 2017 Apr 12;15(1):79. Epub 2017 Apr 12.

Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1186/s12916-017-0836-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389184PMC
April 2017

Differences in MEK inhibitor efficacy in molecularly characterized low-grade serous ovarian cancer cell lines.

Am J Cancer Res 2016 1;6(10):2235-2251. Epub 2016 Oct 1.

Department of Obstetrics & Gynaecology, University of British ColumbiaVancouver, British Columbia, Canada; Department of Surgical Oncology, BC Cancer AgencyVancouver, British Columbia, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088288PMC
October 2016

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.

J Natl Cancer Inst 2016 08 4;108(8). Epub 2016 Jul 4.

Medical Oncology Group, Dept. of Molecular Medicine (ST, AJE, RK, BTH), Department of Pathology (JF, AO, RC, EK), Molecular and Cellular Therapeutics (DO), and Endocrine Oncology Research Group, Department of Surgery (LY), Royal College of Surgeons in Ireland, Dublin, Ireland; RNA Diagnostics Inc., Toronto, Ontario, Canada (LBP, KPHP); Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada (KPHP); Department of Oncology, Beaumont Hospital, Dublin, Ireland (LG, BTH); Department of Oncology, St. James Hospital, Dublin, Ireland (JK); Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland (NO, JC); School of Biomolecular & Biomedical Science, Conway Institute, University College Dublin, Dublin, Ireland (WMG); Department of Medical Oncology, St Vincent's University Hospital, Dublin, Ireland (JC); All Ireland Clinical Oncology Research Group (BTH).

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http://dx.doi.org/10.1093/jnci/djw111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017949PMC
August 2016

Obesity Correlation With Metastases Development and Response to First-Line Metastatic Chemotherapy in Breast Cancer.

Clin Med Insights Oncol 2015 24;9:105-12. Epub 2015 Nov 24.

Our Lady of Lourdes hospital, Drogheda, Co Louth, Ireland.

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http://dx.doi.org/10.4137/CMO.S32812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659439PMC
December 2015

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.

Melanoma Res 2015 Jun;25(3):189-99

aOncoMark Ltd, NovaUCD bDepartment of Medical Oncology, Royal College of Surgeons cUCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin Departments of dPathology eSurgery fMedical Oncology, St Vincent's University Hospital gDepartment of Histopathology, Royal College of Surgeons in Ireland Education and Research Centre, Beaumont Hospital hDepartment of Histopathology, St James's Hospital iDepartment of Histopathology, Trinity College, Dublin jDepartment of Pathology, Cork University Hospital, Cork Departments of kSurgery lMedical Oncology, University Hospital Galway mDepartment of Medicine, National University of Ireland Galway nDepartment of Histopathology, University Hospital Galway, Galway, Ireland oDepartment of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands pLaboratory of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CMR.0000000000000149DOI Listing
June 2015

Immune effects of bevacizumab: killing two birds with one stone.

Cancer Microenviron 2015 Apr 18;8(1):15-21. Epub 2014 Oct 18.

Department of Medical Oncology, Royal College of Surgeons, Beaumont Hospital, Dublin, Ireland,

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http://link.springer.com/10.1007/s12307-014-0160-8
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http://dx.doi.org/10.1007/s12307-014-0160-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449343PMC
April 2015

OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets.

Mol Cancer 2014 Oct 24;13:241. Epub 2014 Oct 24.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/1476-4598-13-241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219121PMC
October 2014

PARP Inhibitors as P-glyoprotein Substrates.

J Pharm Sci 2014 Jun 3;103(6):1913-20. Epub 2014 Apr 3.

Department of Histopathology, St James' Hospital and Trinity College, Dublin, Dublin 8, Ireland.

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http://dx.doi.org/10.1002/jps.23952DOI Listing
June 2014

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

Breast Cancer Res 2013 Oct 1;15(5):R92. Epub 2013 Oct 1.

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http://dx.doi.org/10.1186/bcr3493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907091PMC
October 2013

Increased platelet reactivity in patients with late-stage metastatic cancer.

Cancer Med 2013 Aug 21;2(4):564-70. Epub 2013 May 21.

Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland Dublin, Ireland ; The Biomedical Diagnostics Institute, Dublin City University Dublin, Ireland.

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http://dx.doi.org/10.1002/cam4.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799291PMC
August 2013

Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins.

Mol Oncol 2013 Jun 19;7(3):704-18. Epub 2013 Mar 19.

Department of Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, N-0310 Oslo, Norway.

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http://dx.doi.org/10.1016/j.molonc.2013.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528474PMC
June 2013

Management of unusual histological types of breast cancer.

Oncologist 2012 23;17(9):1135-45. Epub 2012 Jul 23.

Evelyn H. Lauder Breast Center, Memorial Sloan-Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA.

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http://dx.doi.org/10.1634/theoncologist.2012-0134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448406PMC
February 2013

Mechanistic basis for overcoming platinum resistance using copper chelating agents.

Mol Cancer Ther 2012 Nov 21;11(11):2483-94. Epub 2012 Aug 21.

Department of Molecular Pathology, Unit 951, Room 2SCR4.3025, The University of Texas MD Anderson Cancer Center, 7435 Fannin Blvd, Houston, TX 77054, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-12
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http://dx.doi.org/10.1158/1535-7163.MCT-12-0580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496003PMC
November 2012

Network inference using steady-state data and Goldbeter-Koshland kinetics. [corrected].

Bioinformatics 2012 Sep 19;28(18):2342-8. Epub 2012 Jul 19.

Centre for Complexity Science, University of Warwick, CV4 7AL, Coventry, UK.

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http://dx.doi.org/10.1093/bioinformatics/bts459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436851PMC
September 2012

An efficient procedure for protein extraction from formalin-fixed, paraffin-embedded tissues for reverse phase protein arrays.

Proteome Sci 2012 Sep 24;10(1):56. Epub 2012 Sep 24.

Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1186/1477-5956-10-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561137PMC
September 2012

Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing.

Mod Pathol 2012 May 3;25(5):699-708. Epub 2012 Feb 3.

Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/modpathol.2011.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341518PMC
May 2012

Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.

J Cancer Res Clin Oncol 2012 Mar 7;138(3):377-85. Epub 2011 Dec 7.

Department of Epidemiology, Unit 1365, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s00432-011-1103-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526101PMC
March 2012

Dose-adjusting capecitabine minimizes adverse effects while maintaining efficacy: a retrospective review of capecitabine for metastatic breast cancer.

Clin Breast Cancer 2011 Dec;11(6):349-56

Division of Cancer and Surgery, Imperial College Healthcare NHS Trust, Fulham Palace Road,London,

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http://dx.doi.org/10.1016/j.clbc.2011.06.005DOI Listing
December 2011

Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges.

J Oncol 2010 19;2010:568938. Epub 2009 Nov 19.

Department of Systems Biology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://www.hindawi.com/journals/jo/2010/568938/
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http://dx.doi.org/10.1155/2010/568938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796463PMC
July 2011

Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo.

Breast Cancer Res Treat 2011 Jul 29;128(1):69-78. Epub 2010 Jul 29.

Braman Family Breast Cancer Institute, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA.

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http://dx.doi.org/10.1007/s10549-010-1024-7DOI Listing
July 2011

HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer.

Cancer Res 2011 Jul 13;71(13):4412-22. Epub 2011 May 13.

Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130134PMC
July 2011

Molecular targeted therapy in ovarian cancer: what is on the horizon?

Drugs 2011 May;71(8):947-67

Department of Medical Oncology, Beaumont Hospital, Dublin, Ireland.

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http://dx.doi.org/10.2165/11591740-000000000-00000DOI Listing
May 2011

Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.

J Clin Invest 2011 Apr 1;121(4):1231-41. Epub 2011 Apr 1.

Braman Family Breast Cancer Institute, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1172/JCI44145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069769PMC
April 2011

Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors.

Cell Oncol (Dordr) 2011 Feb 15;34(1):55-67. Epub 2011 Feb 15.

Department of Molecular Pathology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s13402-011-0012-1DOI Listing
February 2011

14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.

PLoS One 2011 Jan 10;6(1):e15864. Epub 2011 Jan 10.

Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015864PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018427PMC
January 2011

Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.

J Clin Invest 2010 Jul 7;120(7):2406-13. Epub 2010 Jun 7.

Department of Cancer Biology, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University, Nashville, Tennessee 37232-6307, USA.

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http://www.jci.org/articles/view/41680
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http://dx.doi.org/10.1172/JCI41680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898598PMC
July 2010

Future of personalized medicine in oncology: a systems biology approach.

J Clin Oncol 2010 Jun 20;28(16):2777-83. Epub 2010 Apr 20.

Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.1200/JCO.2009.27.0777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881854PMC
June 2010

Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set.

Mol Cancer Ther 2010 Feb 2;9(2):257-67. Epub 2010 Feb 2.

Department of Melanoma Medical Oncology and Department of Systems Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 0904, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-0743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085051PMC
February 2010

Ovarian cancer.

Lancet 2009 Oct 28;374(9698):1371-82. Epub 2009 Sep 28.

Department of Gynecologic Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/S0140-6736(09)61338-6DOI Listing
October 2009

Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression.

Cancer Res 2009 Jun 2;69(12):5057-64. Epub 2009 Jun 2.

Goodman Cancer Centre and Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151524PMC
June 2009

Androgen receptor levels and association with PIK3CA mutations and prognosis in breast cancer.

Clin Cancer Res 2009 Apr 10;15(7):2472-8. Epub 2009 Mar 10.

Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1763DOI Listing
April 2009

Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

Cancer Cell 2009 Apr;15(4):304-14

Department of Systems Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77054, USA.

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http://dx.doi.org/10.1016/j.ccr.2009.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673492PMC
April 2009

A systems approach to analysis of molecular complexity in breast cancer.

Clin Cancer Res 2009 Jan;15(2):417-9

Department of Systems Biology and the Kleberg Center for Molecular Markers, M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161015PMC
January 2009

RPPAML/RIMS: a metadata format and an information management system for reverse phase protein arrays.

BMC Bioinformatics 2008 Dec 22;9:555. Epub 2008 Dec 22.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1186/1471-2105-9-555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639439PMC
December 2008

Breast carcinoma with neuroendocrine differentiation and myocardial metastases.

Clin Breast Cancer 2007 Dec;7(11):892-4

Department of Gynecologic Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.3816/CBC.2007.n.056DOI Listing
December 2007

Non-parametric quantification of protein lysate arrays.

Bioinformatics 2007 Aug 28;23(15):1986-94. Epub 2007 Jun 28.

Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA.

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http://dx.doi.org/10.1093/bioinformatics/btm283DOI Listing
August 2007

Trends for inflammatory breast cancer: is survival improving?

Oncologist 2007 Aug;12(8):904-12

Department of Breast Medical Oncology, Unit 1354, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030-4009, USA.

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http://dx.doi.org/10.1634/theoncologist.12-8-904DOI Listing
August 2007

Primary angiosarcomas of the breast.

Cancer 2007 Jul;110(1):173-8

Department of Internal Medicine, Mount Sinai Medical Center, Miami Beach, Florida, USA.

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http://dx.doi.org/10.1002/cncr.22784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329779PMC
July 2007

Mammary angiosarcomas: imaging findings in 24 patients.

Radiology 2007 Mar;242(3):725-34

Department of Diagnostic Radiology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1148/radiol.2423060163DOI Listing
March 2007

Identification of remodeling and spacing factor 1 (rsf-1, HBXAP) at chromosome 11q13 as a putative oncogene in ovarian cancer.

Eur J Hum Genet 2006 Apr;14(4):381-3

Department of Molecular Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://www.nature.com/articles/5201570
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http://dx.doi.org/10.1038/sj.ejhg.5201570DOI Listing
April 2006

Exploiting the PI3K/AKT pathway for cancer drug discovery.

Nat Rev Drug Discov 2005 Dec;4(12):988-1004

Department of Molecular Therapeutics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/nrd1902DOI Listing
December 2005

Individualization of neoadjuvant therapy for breast cancer according to molecular tumor characteristics.

Nat Clin Pract Oncol 2005 Dec;2(12):598-9

University of Texas MD Anderson Cancer Center, Houston, TX 77230-1439, USA.

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http://www.nature.com/articles/ncponc0375
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http://dx.doi.org/10.1038/ncponc0375DOI Listing
December 2005

Squamous cell carcinoma of the breast.

J Clin Oncol 2005 Nov;23(31):7827-35

Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA.

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http://jco.ascopubs.org/content/23/31/7827.full.pdf
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http://link.springer.com/content/pdf/10.1007/s12282-009-0146
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http://www.jco.org/cgi/doi/10.1200/JCO.2004.00.9589
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http://dx.doi.org/10.1200/JCO.2004.00.9589DOI Listing
November 2005

Neoadjuvant systemic therapy for breast cancer: an overview and review of recent clinical trials.

Expert Opin Pharmacother 2005 Aug;6(9):1477-91

Department of Breast Medical Oncology, Unit 1354, UT MD Anderson Cancer Center, PO Box 301439, Houston, Texas 77230-1439, USA.

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http://dx.doi.org/10.1517/14656566.6.9.1477DOI Listing
August 2005

New approaches in the treatment of myelofibrosis.

Cancer 2005 Jan;103(1):32-43

Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/cncr.20752DOI Listing
January 2005