Publications by authors named "Bryan J Barratt"

33Publications

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

J Med Genet 2016 12 1;53(12):835-845. Epub 2016 Sep 1.

Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA.

View Article and Find Full Text PDF
December 2016

Differential Genetic Effects on Statin-Induced Changes Across Low-Density Lipoprotein-Related Measures.

Circ Cardiovasc Genet 2015 Oct 13;8(5):688-95. Epub 2015 Aug 13.

From the Division of Preventive Medicine (A.Y.C., F.G., S.M., P.M.R., D.I.C.), Division of Cardiovascular Medicine (S.M., P.M.R.), Division of Genetics (D.I.C.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Personalised Healthcare and Biomarkers AstraZeneca Research and Development, Alderley Park, United Kingdom (B.J.B.); Observational Research Center, AstraZeneca Research and Development, Mölndal (B.D., F.N.); and Unit of Occupational and Environmental Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (F.N.).

View Article and Find Full Text PDF
October 2015

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.

Eur Heart J 2015 Aug 2;36(29):1901-12. Epub 2015 May 2.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.

View Article and Find Full Text PDF
August 2015

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Authors:
Iris Postmus Stella Trompet Harshal A Deshmukh Michael R Barnes Xiaohui Li Helen R Warren Daniel I Chasman Kaixin Zhou Benoit J Arsenault Louise A Donnelly Kerri L Wiggins Christy L Avery Paula Griffin QiPing Feng Kent D Taylor Guo Li Daniel S Evans Albert V Smith Catherine E de Keyser Andrew D Johnson Anton J M de Craen David J Stott Brendan M Buckley Ian Ford Rudi G J Westendorp P Eline Slagboom Naveed Sattar Patricia B Munroe Peter Sever Neil Poulter Alice Stanton Denis C Shields Eoin O'Brien Sue Shaw-Hawkins Y-D Ida Chen Deborah A Nickerson Joshua D Smith Marie Pierre Dubé S Matthijs Boekholdt G Kees Hovingh John J P Kastelein Paul M McKeigue John Betteridge Andrew Neil Paul N Durrington Alex Doney Fiona Carr Andrew Morris Mark I McCarthy Leif Groop Emma Ahlqvist Joshua C Bis Kenneth Rice Nicholas L Smith Thomas Lumley Eric A Whitsel Til Stürmer Eric Boerwinkle Julius S Ngwa Christopher J O'Donnell Ramachandran S Vasan Wei-Qi Wei Russell A Wilke Ching-Ti Liu Fangui Sun Xiuqing Guo Susan R Heckbert Wendy Post Nona Sotoodehnia Alice M Arnold Jeanette M Stafford Jingzhong Ding David M Herrington Stephen B Kritchevsky Gudny Eiriksdottir Leonore J Launer Tamara B Harris Audrey Y Chu Franco Giulianini Jean G MacFadyen Bryan J Barratt Fredrik Nyberg Bruno H Stricker André G Uitterlinden Albert Hofman Fernando Rivadeneira Valur Emilsson Oscar H Franco Paul M Ridker Vilmundur Gudnason Yongmei Liu Joshua C Denny Christie M Ballantyne Jerome I Rotter L Adrienne Cupples Bruce M Psaty Colin N A Palmer Jean-Claude Tardif Helen M Colhoun Graham Hitman Ronald M Krauss J Wouter Jukema Mark J Caulfield

Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.

1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

View Article and Find Full Text PDF
October 2014

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study.

Am Heart J 2014 Jul 4;168(1):96-102.e2. Epub 2014 Apr 4.

Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.

View Article and Find Full Text PDF
July 2014

Lack of association between SLCO1B1 polymorphisms and clinical myalgia following rosuvastatin therapy.

Am Heart J 2013 Jun 10;165(6):1008-14. Epub 2013 Apr 10.

Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.

View Article and Find Full Text PDF
June 2013

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.

Circ Cardiovasc Genet 2012 Dec 1;5(6):676-85. Epub 2012 Nov 1.

Center for Cardiovascular Disease Prevention, the Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.

View Article and Find Full Text PDF
December 2012

Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.

Circ Cardiovasc Genet 2012 Feb 9;5(1):58-65. Epub 2012 Jan 9.

Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women’s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA.

View Article and Find Full Text PDF
February 2012

Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity.

Pharmacogenet Genomics 2007 Nov;17(11):961-72

Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.

View Article and Find Full Text PDF
November 2007

Tacrine-induced liver damage: an analysis of 19 candidate genes.

Pharmacogenet Genomics 2007 Dec;17(12):1091-100

Department of Pharmacology and Therapeutics, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool, UK.

View Article and Find Full Text PDF
December 2007

Gene mapping strategies for complex disease and drug response.

Drug Discov Today Technol 2006 ;3(2):131-6

Research & Development Genetics, AstraZeneca Pharmaceuticals, Mereside, Alderley Park, Macclesfield, Cheshire, UK SK10 4TG.

View Article and Find Full Text PDF
July 2014

Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.

Pharmacogenet Genomics 2006 Apr;16(4):287-96

Department of Pharmacology and Therapeutics, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool, UK.

View Article and Find Full Text PDF
April 2006

Comparison of population- and family-based methods for genetic association analysis in the presence of interacting loci.

Genet Epidemiol 2005 Jul;29(1):51-67

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, UK.

View Article and Find Full Text PDF
July 2005

Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans.

BMC Genet 2005 May 10;6:22. Epub 2005 May 10.

Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital Level 8, Box 116, Cambridge CB2 2QQ, UK.

View Article and Find Full Text PDF
May 2005

Genome-wide association studies: theoretical and practical concerns.

Nat Rev Genet 2005 Feb;6(2):109-18

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, UK.

View Article and Find Full Text PDF
February 2005

Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes.

Diabetes 2004 Sep;53(9):2479-82

JDRF/WT Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2XY, UK.

View Article and Find Full Text PDF
September 2004

Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping.

BMC Biotechnol 2004 Jul 27;4:15. Epub 2004 Jul 27.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes, Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge, CB2 2XY, UK.

View Article and Find Full Text PDF
July 2004

Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.

Diabetes 2004 Feb;53(2):505-9

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.

View Article and Find Full Text PDF
February 2004