Publications by authors named "Bruno Vellas"

100Publications

The genetic architecture of human brainstem structures and their involvement in common brain disorders.

Nat Commun 2020 Aug 11;11(1):4016. Epub 2020 Aug 11.

NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-020-17376-1DOI Listing
August 2020

Antidepressant Use and Progression of Mild to Moderate Alzheimer's Disease: Results from the European ICTUS Cohort.

J Am Med Dir Assoc 2020 Jul 28. Epub 2020 Jul 28.

Department of Geriatric Medicine, Institute of Ageing, Toulouse University Hospital, Toulouse, France; University of Toulouse III, F-31073, Toulouse, France; Inserm URM 1027, F-31073, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jamda.2020.06.028DOI Listing
July 2020

Neuroimaging markers of chronic fatigue in older people: a narrative review.

Aging Clin Exp Res 2020 Jul 30. Epub 2020 Jul 30.

Gérontopôle of Toulouse, Toulouse University Hospital (CHU Toulouse), Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40520-020-01666-1DOI Listing
July 2020

Cross-sectional and prospective associations between cerebral cortical thickness and frailty in older adults.

Exp Gerontol 2020 Jul 11;139:111018. Epub 2020 Jul 11.

Gerontopole of Toulouse, Institute of Ageing, Toulouse University Hospital (CHU Toulouse), Toulouse, France; UPS/Inserm UMR1027, University of Toulouse III, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2020.111018DOI Listing
July 2020

Prospective associations between physical activity levels and white matter integrity in older adults: results from the MAPT study.

Maturitas 2020 Jul 23;137:24-29. Epub 2020 Apr 23.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, 37 allée Jules Guesde, 31000 Toulouse, France; UPS/INSERM UMR 1027, University of Toulouse III, Toulouse, France Faculté de médecine 37 allées Jules Guesde 31000 Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.maturitas.2020.04.012DOI Listing
July 2020

Future avenues for Alzheimer's disease detection and therapy: Liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery.

Neuropharmacology 2020 May 11:108081. Epub 2020 May 11.

Sorbonne University, GRC N° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de L'hôpital, F-75013, Paris, France; Brain & Spine Institute (ICM), INSERM U 1127, CNRS UMR 7225, Boulevard de L'hôpital, F-75013, Paris, France; Institute of Memory and Alzheimer's Disease (IM2A), Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Boulevard de L'hôpital, F-75013, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuropharm.2020.108081DOI Listing
May 2020

Re: Prospective Associations between Diffusion Tensor Imaging Parameters and Frailty in Older Adults.

J Am Geriatr Soc 2020 Apr 16. Epub 2020 Apr 16.

for the MAPT/DSA Study Group Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.16456DOI Listing
April 2020

Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study.

Clin Nutr 2020 Mar 16. Epub 2020 Mar 16.

Inserm UMR 1027, Université de Toulouse III Paul Sabatier, Faculté de Médecine Toulouse Purpan, 37 Allées Jules Guesde, Toulouse Cedex 9, 31 000, Toulouse, France; Unité de Soutien Méthodologique à La Recherche CHU de Toulouse, Faculté de Médecine Toulouse Purpan, 37 Allées Jules Guesde, Toulouse Cedex 9, 31 000 Toulouse, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clnu.2020.03.011DOI Listing
March 2020

Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults.

J Am Geriatr Soc 2020 May 25;68(5):1050-1055. Epub 2020 Jan 25.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.16343DOI Listing
May 2020

Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain.

Nat Neurosci 2020 Feb;23(2):295

NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41593-019-0553-6DOI Listing
February 2020

Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The MAPT study.

Exp Gerontol 2019 12 25;128:110758. Epub 2019 Oct 25.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, 37 allée Jules Guesdes, 31000 Toulouse, France; UMR INSERM, 1027 University of Toulouse III, Toulouse, France Faculté de médecine, 37 allées Jules Guesde, 31000 Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2019.110758DOI Listing
December 2019

Genetic architecture of subcortical brain structures in 38,851 individuals.

Authors:
Claudia L Satizabal Hieab H H Adams Derrek P Hibar Charles C White Maria J Knol Jason L Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V Roshchupkin Albert V Smith Joshua C Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J van der Lee Jingyun Yang Lisa R Yanek Tom V Lee Shuo Li Yanhui Hu Jia Yu Koh John D Eicher Sylvane Desrivières Alejandro Arias-Vasquez Ganesh Chauhan Lavinia Athanasiu Miguel E Rentería Sungeun Kim David Hoehn Nicola J Armstrong Qiang Chen Avram J Holmes Anouk den Braber Iwona Kloszewska Micael Andersson Thomas Espeseth Oliver Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz-Santiañez Bernd Kraemer Asta K Håberg Hannah J Jones G Bruce Pike Dan J Stein Allison Stevens Janita Bralten Meike W Vernooij Tamara B Harris Irina Filippi A Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H Mosley James T Becker Nhat Trung Doan Saskia P Hagenaars Yasaman Saba Gabriel Cuellar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza-Schreiber Konstantinos Arfanakis Diane M Becker David Ames Aaron L Goldman Phil H Lee Dorret I Boomsma Simon Lovestone Sudheer Giddaluru Stephanie Le Hellard Manuel Mattheisen Marc M Bohlken Dalia Kasperaviciute Lianne Schmaal Stephen M Lawrie Ingrid Agartz Esther Walton Diana Tordesillas-Gutierrez Gareth E Davies Jean Shin Jonathan C Ipser Louis N Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K Haukvik Benjamin S Aribisala Helena Schmidt Lachlan T Strike Ching-Yu Cheng Shannon L Risacher Benno Pütz Debra A Fleischman Amelia A Assareh Venkata S Mattay Randy L Buckner Patrizia Mecocci Anders M Dale Sven Cichon Marco P Boks Mar Matarin Brenda W J H Penninx Vince D Calhoun M Mallar Chakravarty Andre F Marquand Christine Macare Shahrzad Kharabian Masouleh Jaap Oosterlaan Philippe Amouyel Katrin Hegenscheid Jerome I Rotter Andrew J Schork David C M Liewald Greig I de Zubicaray Tien Yin Wong Li Shen Philipp G Sämann Henry Brodaty Joshua L Roffman Eco J C de Geus Magda Tsolaki Susanne Erk Kristel R van Eijk Gianpiero L Cavalleri Nic J A van der Wee Andrew M McIntosh Randy L Gollub Kazima B Bulayeva Manon Bernard Jennifer S Richards Jayandra J Himali Markus Loeffler Nanda Rommelse Wolfgang Hoffmann Lars T Westlye Maria C Valdés Hernández Narelle K Hansell Theo G M van Erp Christiane Wolf John B J Kwok Bruno Vellas Andreas Heinz Loes M Olde Loohuis Norman Delanty Beng-Choon Ho Christopher R K Ching Elena Shumskaya Baljeet Singh Albert Hofman Dennis van der Meer Georg Homuth Bruce M Psaty Mark E Bastin Grant W Montgomery Tatiana M Foroud Simone Reppermund Jouke-Jan Hottenga Andrew Simmons Andreas Meyer-Lindenberg Wiepke Cahn Christopher D Whelan Marjolein M J van Donkelaar Qiong Yang Norbert Hosten Robert C Green Anbupalam Thalamuthu Sebastian Mohnke Hilleke E Hulshoff Pol Honghuang Lin Clifford R Jack Peter R Schofield Thomas W Mühleisen Pauline Maillard Steven G Potkin Wei Wen Evan Fletcher Arthur W Toga Oliver Gruber Matthew Huentelman George Davey Smith Lenore J Launer Lars Nyberg Erik G Jönsson Benedicto Crespo-Facorro Nastassja Koen Douglas N Greve André G Uitterlinden Daniel R Weinberger Vidar M Steen Iryna O Fedko Nynke A Groenewold Wiro J Niessen Roberto Toro Christophe Tzourio William T Longstreth M Kamran Ikram Jordan W Smoller Marie-Jose van Tol Jessika E Sussmann Tomas Paus Hervé Lemaître Matthias L Schroeter Bernard Mazoyer Ole A Andreassen Florian Holsboer Chantal Depondt Dick J Veltman Jessica A Turner Zdenka Pausova Gunter Schumann Daan van Rooij Srdjan Djurovic Ian J Deary Katie L McMahon Bertram Müller-Myhsok Rachel M Brouwer Hilkka Soininen Massimo Pandolfo Thomas H Wassink Joshua W Cheung Thomas Wolfers Jean-Luc Martinot Marcel P Zwiers Matthias Nauck Ingrid Melle Nicholas G Martin Ryota Kanai Eric Westman René S Kahn Sanjay M Sisodiya Tonya White Arvin Saremi Hans van Bokhoven Han G Brunner Henry Völzke Margaret J Wright Dennis van 't Ent Markus M Nöthen Roel A Ophoff Jan K Buitelaar Guillén Fernández Perminder S Sachdev Marcella Rietschel Neeltje E M van Haren Simon E Fisher Alexa S Beiser Clyde Francks Andrew J Saykin Karen A Mather Nina Romanczuk-Seiferth Catharina A Hartman Anita L DeStefano Dirk J Heslenfeld Michael W Weiner Henrik Walter Pieter J Hoekstra Paul A Nyquist Barbara Franke David A Bennett Hans J Grabe Andrew D Johnson Christopher Chen Cornelia M van Duijn Oscar L Lopez Myriam Fornage Joanna M Wardlaw Reinhold Schmidt Charles DeCarli Philip L De Jager Arno Villringer Stéphanie Debette Vilmundur Gudnason Sarah E Medland Joshua M Shulman Paul M Thompson Sudha Seshadri M Arfan Ikram

Nat Genet 2019 11 21;51(11):1624-1636. Epub 2019 Oct 21.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055269PMC
November 2019

Estimated Glomerular Filtration Rate Decline and Incident Frailty in Older Adults.

Clin J Am Soc Nephrol 2019 11 18;14(11):1597-1604. Epub 2019 Oct 18.

Gerontopole of Toulouse, Institute of Aging, Toulouse University Hospital (CHU Toulouse), Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2215/CJN.03750319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832058PMC
November 2019

Multidomain intervention and/or omega-3 in nondemented elderly subjects according to amyloid status.

Alzheimers Dement 2019 11 23;15(11):1392-1401. Epub 2019 Sep 23.

INSERM UMR 1027, Toulouse, France; University of Toulouse III, Toulouse, France; Department of Epidemiology and Public Health, Toulouse CHU, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2019.07.008DOI Listing
November 2019

Common brain disorders are associated with heritable patterns of apparent aging of the brain.

Nat Neurosci 2019 10 24;22(10):1617-1623. Epub 2019 Sep 24.

NORMENT, Division of Mental Health and Addiction Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41593-019-0471-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823048PMC
October 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Sep;51(9):1423-1424

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265117PMC
September 2019

The association between apathy and frailty in older adults: a new investigation using data from the Mapt study.

Aging Ment Health 2019 Aug 14:1-5. Epub 2019 Aug 14.

a Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse , France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13607863.2019.1650890DOI Listing
August 2019

Body Weight Variation Patterns as Predictors of Cognitive Decline over a 5 Year Follow-Up among Community-Dwelling Elderly (MAPT Study).

Nutrients 2019 Jun 18;11(6). Epub 2019 Jun 18.

Gerontopole of Toulouse, Institute of Ageing, Toulouse University Hospital (CHU Toulouse), 31000 Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11061371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627683PMC
June 2019

Association of 3-Year Multidomain Intervention and Omega-3 Supplementation with Frailty Incidence.

J Am Geriatr Soc 2019 08 6;67(8):1700-1706. Epub 2019 Jun 6.

Gérontopôle of Toulouse, Institute of Aging, Toulouse University Hospital (CHU Toulouse), Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.15994DOI Listing
August 2019

Neuropsychiatric Symptoms and Risk of Progression to Alzheimer's Disease Among Mild Cognitive Impairment Subjects.

J Alzheimers Dis 2019 ;70(1):25-34

Gerontopôle, INSERM U 1027, Alzheimer's Disease Research and Clinical Center, Toulouse University Hospital, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-190025DOI Listing
January 2019

Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials.

Alzheimers Dement 2019 06 30;15(6):729-741. Epub 2019 Apr 30.

INSERM-University of Toulouse UMR 1027, Toulouse, France; Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2019.03.005DOI Listing
June 2019

Factors associated with changes of the frailty status after age 70: Findings in the MAPT study.

Ann Epidemiol 2019 06 28;34:65-70.e1. Epub 2019 Mar 28.

LEASP, UMR 1027, INSERM, UPS, Université de Toulouse, Toulouse, France; Department of Public Health, CHU de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annepidem.2019.03.008DOI Listing
June 2019

Randomized Trial of Verubecestat for Prodromal Alzheimer's Disease.

N Engl J Med 2019 Apr;380(15):1408-1420

From Merck, Kenilworth, NJ (M.F.E., J.K., T.V., Y. Mukai, Y.Z., W.L., C.F., E.M., L.H.M., Y. Mo, C.S., D.M.); the University of Southern California, San Diego (P.S.A.); Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas (J.L.C.); Banner Alzheimer's Institute, Phoenix, AZ (P.N.T.); Gerontopole, INSERM Unité 1027, Alzheimer's Disease Research and Clinical Center, Toulouse University Hospital, Toulouse, France (B.V.); Yale University School of Medicine, New Haven, CT (C.H.D.); and the Research Center and Memory Clínic, Fundació Alzheimer Centre Educacional, Institut Català de Neurociènces Aplicades-Universitat Internacional de Catalunya, Barcelona, and the Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid - both in Spain (M.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1812840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776078PMC
April 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Lifestyle multidomain intervention, omega-3 supplementation, or both for reducing the risk of developing clinically relevant depressive symptoms in older adults with memory complaints? Secondary analysis from the MAPT trial.

Exp Gerontol 2019 06 26;120:28-34. Epub 2019 Feb 26.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, 37 allée Jules Guesdes, 31000 Toulouse, France; UMR INSERM, 1027 University of Toulouse III, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2019.02.010DOI Listing
June 2019

Potentially modifiable factors associated with agitation and aggression in Alzheimer's disease: results of the ICTUS study.

Int Psychogeriatr 2019 10;31(10):1509-1516

Alzheimer's Disease Research and Clinical Center, Gérontopôle, Toulouse University Hospital, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610218001990DOI Listing
October 2019

Cognitive changes of older adults with an equivocal amyloid load.

J Neurol 2019 Apr 28;266(4):835-843. Epub 2019 Jan 28.

Gérontopôle de Toulouse, Centre Hospitalo-Universitaire de Toulouse (CHU Toulouse), Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-019-09203-5DOI Listing
April 2019

Prospective association of white matter hyperintensity volume and frailty in older adults.

Exp Gerontol 2019 04 10;118:51-54. Epub 2019 Jan 10.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, 37 allée Jules Guesdes, 31000 Toulouse, France; UMR INSERM, 1027 University of Toulouse III, Faculté de médecine, 37 allées Jules Guesde, 31000 Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2019.01.007DOI Listing
April 2019

Association Between Brain β-Amyloid and Frailty in Older Adults.

J Gerontol A Biol Sci Med Sci 2019 10;74(11):1747-1752

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, France.

View Article

Download full-text PDF

Source
https://academic.oup.com/biomedgerontology/advance-article/d
Publisher Site
http://dx.doi.org/10.1093/gerona/glz009DOI Listing
October 2019

Benzodiazepines and frail elderly people: how prescribing can be optimized?

Geriatr Psychol Neuropsychiatr Vieil 2018 Dec;16(4):359-366

Pôle pharmacie, CHU de Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/pnv.2018.0755DOI Listing
December 2018

Ready-meal consumption in older people: association with obesity and dietary intake.

Aging Clin Exp Res 2019 Jun 23;31(6):855-861. Epub 2018 Oct 23.

Institut du Vieillissement, Gérontopôle, Université Toulouse III Paul Sabatier, 37, Allées Jules Guesde, 31000, Toulouse, France.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s40520-018-1043-5
Publisher Site
http://dx.doi.org/10.1007/s40520-018-1043-5DOI Listing
June 2019

Effect of Relocation on Neuropsychiatric Symptoms in Elderly Adults Living in Long-Term Care.

J Am Geriatr Soc 2018 11 8;66(11):2183-2187. Epub 2018 Oct 8.

Gérontopôle, Department of Internal Medicine and Geriatrics, Toulouse University Hospital, Toulouse, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/jgs.15612
Publisher Site
http://dx.doi.org/10.1111/jgs.15612DOI Listing
November 2018

Effect of Exercise on Behavioral Symptoms and Pain in Patients With Dementia Living in Nursing Homes.

Am J Alzheimers Dis Other Demen 2019 03 3;34(2):89-94. Epub 2018 Oct 3.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518803773
Publisher Site
http://dx.doi.org/10.1177/1533317518803773DOI Listing
March 2019

Relationship Between Brain Amyloid Deposition and Instrumental Activities of Daily Living in Older Adults: A Longitudinal Study from the Multidomain Alzheimer Prevention Trial.

J Am Geriatr Soc 2018 10 12;66(10):1940-1947. Epub 2018 Sep 12.

Department of Internal Medicine and Geriatrics, Gérontopôle, University of Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.15497DOI Listing
October 2018

Stability of graph theoretical measures in structural brain networks in Alzheimer's disease.

Sci Rep 2018 08 2;8(1):11592. Epub 2018 Aug 2.

Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-29927-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072788PMC
August 2018

Associations of Multidomain Lifestyle Intervention with Frailty: Secondary Analysis of a Randomized Controlled Trial.

Am J Med 2018 11 1;131(11):1382.e7-1382.e13. Epub 2018 Jul 1.

Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, France; Unité Mixte de Recherche (UMR) Institut National de la Santé et de la recherche médicale (INSERM) 1027, University of Toulouse III, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjmed.2018.06.002DOI Listing
November 2018

Six-month observational follow-up on activities of daily living in people with dementia living in nursing homes after a 6-month group based on either exercise or social activities.

Aging Clin Exp Res 2019 Mar 7;31(3):361-366. Epub 2018 Jun 7.

Gérontopôle de Toulouse, Institut du Vieillissement, Bâtiment B, Centre Hospitalo-Universitaire de Toulouse, 37 Allée Jules Guesdes, 31000, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40520-018-0984-zDOI Listing
March 2019

Burden of Frailty in Post-Disaster Low-Income Countries: An Example From Nepal.

Disaster Med Public Health Prep 2019 04 30;13(2):104. Epub 2018 May 30.

1Gérontopôle,Department of Geriatrics,University Hospital of Toulouse,Toulouse,France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/dmp.2018.50DOI Listing
April 2019

Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer's Disease.

N Engl J Med 2018 05;378(18):1691-1703

From Merck Research Laboratories, Merck, Kenilworth, NJ (M.F.E., J.K., C.S., Y. Mukai, T.V., C.F., E.M., L.H.M., Y. Mo, D.M.); Banner Alzheimer's Institute, Phoenix, AZ (P.N.T.); University of Southern California, San Diego (P.S.A.); Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas (J.L.C.); Gerontopole, INSERM Unité 1027, Alzheimer's Disease Research and Clinical Center, Toulouse University Hospital, Toulouse, France (B.V.); and Leuven Institute of Neuroscience and Disease, Alzheimer Research Center, and the Laboratory for Cognitive Neurology, Department of Neurosciences, Katholieke Universiteit Leuven, and Neurology, University Hospitals - both in Leuven, Belgium (R.V.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1706441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776074PMC
May 2018

Chronically raised C-reactive protein is inversely associated with cortical β-amyloid in older adults with subjective memory complaints.

Exp Gerontol 2018 07 25;108:226-230. Epub 2018 Apr 25.

Gérontopôle, Department of Geriatrics, CHU Toulouse, Purpan University Hospital, Toulouse, France; UMR1027 INSERM, Université de Toulouse III Paul Sabatier, Toulouse, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2018.04.014DOI Listing
July 2018

Resource Use and Cost of Alzheimer's Disease in France: 18-Month Results from the GERAS Observational Study.

Value Health 2018 03 11;21(3):295-303. Epub 2017 Nov 11.

Gerontopole, INSERM UMR1027, Toulouse University Hospital, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jval.2017.09.019DOI Listing
March 2018

Prospective associations between white matter hyperintensities and lower extremity function.

Neurology 2018 04 9;90(15):e1291-e1297. Epub 2018 Mar 9.

From Gerontopole of Toulouse (S.Y.M., P.d.S.B., Y.R., S.A., M.C., B.V.) and Department of Epidemiology and Public Health (S.A.), University Hospital of Toulouse (CHU-Toulouse); UMR INSERM 1027 (S.Y.M., P.d.S.B., Y.R., S.A., M.C., B.V.), University of Toulouse III, France; Department of Neurology (S.Y.M.), Ajou University School of Medicine, Kyungki-do, Republic of Korea; UPMC Univ Paris 06 (M.C.), UMR S 1127, ICM, Sorbonne Universités; Inserm (M.C.), U1127; CNRS (M.C.), UMR 7225; ICM (M.C.); Inria Paris-Rocquencourt (M.C.), Paris; UNATI (J.F.M.), Neurospin, CEA, Université Paris-Saclay, Gif-sur-Yvette; and CATI Multicenter Neuroimaging Platform (A.B., L.F., J.F.M., M.C.), cati-neuroimaging.com, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000005289DOI Listing
April 2018

Heterogeneous patterns of brain atrophy in Alzheimer's disease.

Neurobiol Aging 2018 05 31;65:98-108. Epub 2018 Jan 31.

Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden; Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2018.01.009DOI Listing
May 2018

Untangling the overlap between frailty and low lean mass: Data from Toulouse frailty day hospital.

Arch Gerontol Geriatr 2018 Mar - Apr;75:209-213. Epub 2017 Dec 29.

Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; Inserm UMR1027, Université de Toulouse III Paul Sabatier, Toulouse, France.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01674943173035
Publisher Site
http://dx.doi.org/10.1016/j.archger.2017.12.013DOI Listing
March 2019

Evidence for the Domains Supporting the Construct of Intrinsic Capacity.

J Gerontol A Biol Sci Med Sci 2018 11;73(12):1653-1660

Department of Ageing and Life Course, World Health Organization, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/gly011DOI Listing
November 2018

Frailty Screening (FRAIL-NH) and Mortality in French Nursing Homes: Results From the Incidence of Pneumonia and Related Consequences in Nursing Home Residents Study.

J Am Med Dir Assoc 2018 05;19(5):411-414

Aged and Extended Care Services, The Queen Elizabeth Hospital, Central Adelaide Local Health Network, Adelaide, South Australia, Australia; National Health and Medical Research Council Center of Research Excellence in Frailty and Healthy Aging, Australia; Adelaide Geriatric Training and Research with Aged Care (GTRAC) Centre, School of medicine, The University of Adelaide, Adelaide, South Australia, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jamda.2017.12.101DOI Listing
May 2018

Impact of diabetes on caregiver stress in patients with Alzheimer's disease: data from the ICTUS study.

Int Psychogeriatr 2018 08 30;30(8):1109-1117. Epub 2018 Jan 30.

The Center of Gerontology and Geriatrics,West China Medical School/West China Hospital,Sichuan University,Chengdu,Sichuan,China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610217002460DOI Listing
August 2018

Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.

N Engl J Med 2018 01;378(4):321-330

From the Department of Neurology and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York (L.S.H.); Gérontopôle, Centre Hospitalier Universitaire Toulouse, Unité Mixte de Recherche INSERM Unité 1027 Université Toulouse III-Paul Sabatier, Toulouse, France (B.V.); Austin Health Continuing Care Clinical Service Unit, Heidelberg, and the University of Melbourne, Melbourne, VIC - both in Australia (M.W.); Fundació ACE, Alzheimer Research Center and Memory Clinic, Institut Català de Neurociències Aplicades, Barcelona (M. Boada); Kingshill Research Centre, Victoria Hospital, Swindon, United Kingdom (R.B.); the Division of Geriatric Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada (M. Borrie); Clinic for Medicine of the Elderly, Diakovere Henriettenstift, Hannover, Germany (K.H.); Karolinska Institutet Alzheimer's Disease Research Center and Clinical Trial Unit, Geriatric Clinic, Karolinska University Hospital, Huddinge, Sweden (N.A.); the Department of Pathophysiology and Transplantation, Neurology Unit, Dino Ferrari Center, University of Milan, Fondazione Ca' Granda, Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Policlinico, Milan (E. Scarpini); Eli Lilly (H.L.-S., M.C., A.H., K.S., V.P.H., C.C., R.K., M.M., R.D., K.J.S., E. Siemers) and the Department of Pathology and Laboratory Medicine, Indiana University School of Medicine (R.A.D.) - both in Indianapolis; and Avid Radiopharmaceuticals, Philadelphia (M.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1705971DOI Listing
January 2018

Chronic inflammation and sarcopenia: A regenerative cell therapy perspective.

Exp Gerontol 2018 03 10;103:115-123. Epub 2018 Jan 10.

Gérontopôle, Department of Geriatrics, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; INSERM, UMR1027, Université de Toulouse III Paul Sabatier, Toulouse, France; Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Università di Milano, Milan, Italy.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S05315565173082
Publisher Site
http://dx.doi.org/10.1016/j.exger.2017.12.023DOI Listing
March 2018

Costs of Care of Agitation Associated With Dementia in 8 European Countries: Results From the RightTimePlaceCare Study.

J Am Med Dir Assoc 2018 01;19(1):95.e1-95.e10

UMR1027, University of Toulouse, UPS, Inserm, Toulouse, France; Gerontopole, Alzheimer's Disease Research and Clinical Center, University Hospital of Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15258610173058
Publisher Site
http://dx.doi.org/10.1016/j.jamda.2017.10.013DOI Listing
January 2018

Exercise Training for Preventing Dementia, Mild Cognitive Impairment, and Clinically Meaningful Cognitive Decline: A Systematic Review and Meta-analysis.

J Gerontol A Biol Sci Med Sci 2018 10;73(11):1504-1511

Gerontopole of Toulouse, Institute on Aging, Toulouse University Hospital (CHU Toulouse), France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/glx234DOI Listing
October 2018

Cross-sectional Associations of Fatigue with Cerebral β-Amyloid in Older Adults at Risk of Dementia.

Front Med (Lausanne) 2017 6;4:173. Epub 2017 Nov 6.

Gérontopôle, Department of Geriatrics, CHU Toulouse, Purpan University Hospital, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmed.2017.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681742PMC
November 2017

Motoric Cognitive Risk Syndrome: Predictor of Dementia and Age-Related Negative Outcomes.

Front Med (Lausanne) 2017 25;4:166. Epub 2017 Oct 25.

Gérontopôle, Department of Geriatrics, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmed.2017.00166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660976PMC
October 2017

Lower brain and blood nutrient status in Alzheimer's disease: Results from meta-analyses.

Alzheimers Dement (N Y) 2017 Sep 24;3(3):416-431. Epub 2017 Jun 24.

Nutricia Research, Nutricia Advanced Medical Nutrition, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.trci.2017.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651428PMC
September 2017

Optimization of drug therapy in elderly individuals admitted to a geriatric unit.

Clin Interv Aging 2017 11;12:1691-1696. Epub 2017 Oct 11.

Gérontopôle, Centre Hospitalier Universitaire Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/CIA.S132309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644527PMC
April 2018

Physical status and frailty index in nursing home residents: Results from the INCUR study.

Arch Gerontol Geriatr 2018 Jan 12;74:72-76. Epub 2017 Oct 12.

Gérontopôle CHU de Toulouse, France; UMR 1027 INSERM, Université Toulouse 3, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.archger.2017.10.005DOI Listing
January 2018

Memory Complaints and Cognitive Decline: Data from the GUIDAGE Study1.

J Alzheimers Dis 2017 ;60(4):1567-1578

Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-170229DOI Listing
July 2018

Physical activity domains and cognitive function over three years in older adults with subjective memory complaints: Secondary analysis from the MAPT trial.

J Sci Med Sport 2018 Jan 26;21(1):52-57. Epub 2017 Jul 26.

University Hospital of Toulouse (CHU-Toulouse), Gérontopôle, Institute on Aging, France; University of Toulouse III, Inserm/UPS UMR1027, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsams.2017.07.019DOI Listing
January 2018

Association Between Frailty and Cognitive Impairment: Cross-Sectional Data From Toulouse Frailty Day Hospital.

J Am Med Dir Assoc 2017 Nov 7;18(11):990.e1-990.e5. Epub 2017 Aug 7.

Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; Inserm UMR1027, Université de Toulouse III Paul Sabatier, Toulouse, France.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15258610173036
Publisher Site
http://dx.doi.org/10.1016/j.jamda.2017.06.024DOI Listing
November 2017

How clinical practitioners assess frailty in their daily practice: an international survey.

Aging Clin Exp Res 2017 Oct 2;29(5):905-912. Epub 2017 Aug 2.

Gérontopôle de Toulouse, Département de Médecine Interne et Gérontologie Clinique, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40520-017-0806-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589778PMC
October 2017