Bruno Clément

New insights into quetiapine metabolism using molecular networking.

Authors:

Brendan Le Daré Pierre-Jean Ferron Pierre-Marie Allard Bruno Clément Isabelle Morel Thomas Gicquel

Sci Rep 2020 11 16;10(1):19921. Epub 2020 Nov 16.

INSERM, INRAE, CHU Rennes, Institut NuMeCan (Nutrition, Metabolism and Cancer), PREVITOX Network, Univ Rennes, 35033, Rennes, France.

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November 2020

Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury?

Authors:

Pierre-Jean Ferron Thomas Gicquel Bruno Mégarbane Bruno Clément Bernard Fromenty

Biochimie 2020 Dec 3;179:266-274. Epub 2020 Sep 3.

INSERM, Univ Rennes, INRAE, Institut NUMECAN (Nutrition Metabolisms and Cancer) UMR_A 1341, UMR_S 1241, F-35000, Rennes, France. Electronic address:

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December 2020

Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma.

Authors:

Fabien Robin Gaëlle Angenard Luis Cano Laetitia Courtin-Tanguy Elodie Gaignard Zine-Eddine Khene Damien Bergeat Bruno Clément Karim Boudjema Cédric Coulouarn Laurent Sulpice

Br J Cancer 2020 Jul 7;123(1):72-80. Epub 2020 May 7.

Univ Rennes, Inserm, Inra, CHU Rennes, Service de Chirurgie Hépatobiliaire et Digestive, Institut NuMeCan (Nutrition Metabolisms and Cancer), UMR_S 1241, Rennes, France.

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July 2020

TDP-43-Mediated Toxicity in HEK293T Cells: A Fast and Reproducible Protocol To Be Employed in the Search of New Therapeutic Options against Amyotrophic Lateral Sclerosis.

Authors:

Débora Lanznaster Jérôme Bourgeais Clement Bruno Rudolf C Hergesheimer Rose-Anne Thepault Patrick Vourc'h Philippe Corcia Christian R Andres Olivier Herault Hélène Blasco

Cells 2019 Dec 26;9(1). Epub 2019 Dec 26.

UMR 1253, iBrain, University of Tours, Inserm, 37000 Tours, France.

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December 2019

Urinary TIMP-2 and MMP-2 are significantly associated with poor bladder compliance in adult patients with spina bifida.

Authors:

Benoit Peyronnet Claire Richard Claude Bendavid Florian Naudet Juliette Hascoet Charlène Brochard Nelly Senal Magali Jezequel Quentin Alimi Zine-Eddine Khene Anne Corlu Bruno Clément Laurent Siproudhis Guillaume Bouguen Jacques Kerdraon Andrea Manunta Xavier Gamé

Neurourol Urodyn 2019 11 4;38(8):2151-2158. Epub 2019 Sep 4.

Département d'Urologie, Transplantation Rénale et Andrologie, CHU Rangueil, Toulouse, France.

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November 2019

Raman spectroscopic screening of high and low molecular weight fractions of human serum.

Authors:

Drishya Rajan Parachalil Clément Bruno Franck Bonnier Hélène Blasco Igor Chourpa Jennifer McIntyre Hugh J Byrne

Analyst 2019 Jul 12;144(14):4295-4311. Epub 2019 Jun 12.

FOCAS Research Institute, Technological University Dublin, Kevin Street, Dublin 8, Ireland.

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July 2019

[Determination of thresholds values for platelet serotonin and urinary 5-HIAA concentrations for the biological diagnosis of digestive neuroendocrine tumors].

Authors:

Maël Padelli Clément Bruno Julia Lemarchand Patrick Vourc'h Christian Andres Hélène Blasco Isabelle Benz-de Bretagne

Ann Biol Clin (Paris) 2019 04;77(2):161-168

Laboratoire de biochimie et biologie moléculaire, CHRU de Tours, France, UMR 1253, iBrain, Université de Tours, Inserm, Tours, France.

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April 2019

Analysis of bodily fluids using vibrational spectroscopy: a direct comparison of Raman scattering and infrared absorption techniques for the case of glucose in blood serum.

Authors:

Drishya Rajan Parachalil Clément Bruno Franck Bonnier Hélène Blasco Igor Chourpa Matthew J Baker Jennifer McIntyre Hugh J Byrne

Analyst 2019 May;144(10):3334-3346

FOCAS Research Institute, Technological University Dublin, Kevin Street, Dublin 8, Ireland.

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May 2019

DNAshell Protects DNA Stored at Room Temperature for Downstream Next-Generation Sequencing Studies.

Authors:

Kevin Washetine Simon Heeke Camille Ribeyre Camille Bourreau Corinne Normand Hélène Blons Pierre Laurent-Puig Claire Mulot Dominique Clermont Maha David Bruno Clément Georges Dagher Paul Hofman

Biopreserv Biobank 2019 Aug 26;17(4):352-354. Epub 2019 Mar 26.

1Laboratoire de Pathologie Clinique et Experimentale, Biobanque BB-0033-00025, FHU OncoAge, Université Côte d'Azur, Nice, France.

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August 2019

[Tumor banks and complex data management: Current and future challenges].

Authors:

Paul Hofman Georges Dagher Pierre Laurent-Puig Charles-Hugo Marquette Fabrice Barlesi Frédéric Bibeau Bruno Clément

Ann Pathol 2019 Apr 25;39(2):137-143. Epub 2019 Feb 25.

Inserm, Inra, nutrition métabolismes et cancer, CRB-Santé, université de Rennes, rue Henri-Le-Guilloux, 35033 Rennes, France.

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April 2019

The bidirectional crosstalk between metastatic uveal melanoma cells and hepatic stellate cells engenders an inflammatory microenvironment.

Authors:

Narjes Babchia Solange Landreville Bruno Clément Cédric Coulouarn Frédéric Mouriaux

Exp Eye Res 2019 04 13;181:213-222. Epub 2019 Feb 13.

Inserm, Université de Rennes 1, UMR 1241, Nutrition, Métabolismes et Cancer (NuMeCan), Rennes, France; Département d'ophtalmologie, Faculté de Médecine, Université Laval, Québec, Canada; Centre Universitaire d'ophtalmologie-Recherche and Axe Médecine Régénératrice, Centre de Recherche du CHU de Québec-Université Laval, Québec, Canada; Centre de Recherche en Organogénèse Expérimentale de l'Université Laval/LOEX, Québec, Canada; Service d'ophtalmologie, CHU de Rennes, Rennes, France. Electronic address:

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April 2019

Establishing a Dedicated Lung Cancer Biobank at the University Center Hospital of Nice (France). Why and How?

Cancers (Basel) 2018 Jun 29;10(7). Epub 2018 Jun 29.

Hospital-Integrated Biobank (BB-0033-00025), Université Côte d'Azur, CHU de Nice, 06001 Nice CEDEX 1, France.

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June 2018

Ensuring the Safety and Security of Frozen Lung Cancer Tissue Collections through the Encapsulation of Dried DNA.

Cancers (Basel) 2018 Jun 11;10(6). Epub 2018 Jun 11.

Hospital-Integrated Biobank (BB-0033-00025), Université Côte d'Azur, CHU de Nice, 06001 Nice CEDEX 1, France.

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June 2018

Integrating Biobank Data into a Clinical Data Research Network: The IBCB Project.

Authors:

Guillaume Bouzille Vianney Jouhet Bruno Turlin Bruno Clement Mireille Desille Christine Riou Moufid Hajjar Denis Delamarre Danielle Le Quilleuc Frantz Thiessard Marc Cuggia

Stud Health Technol Inform 2018 ;247:16-20

Inserm, Univ Rennes, CHU Rennes, Inra, Laboratoire Traitement du Signal et de l'Image (LTSI-U1099), CIC-1414, Centre de Données Cliniques, Nutrition Metabolisms and Cancer (NuMeCan), The liver biobanks network, CRB-Santé, Biosit, Biogenouest, Rennes, France.

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June 2018

A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma.

Authors:

Aude Merdrignac Gaëlle Angenard Coralie Allain Kilian Petitjean Damien Bergeat Pascale Bellaud Allain Fautrel Bruno Turlin Bruno Clément Steven Dooley Laurent Sulpice Karim Boudjema Cédric Coulouarn

Hepatol Commun 2018 03 30;2(3):254-269. Epub 2018 Jan 30.

Institut National de la Santé et de la Recherche Médicale, INRA, Université de Rennes, CHU Rennes, UMR 1241, Nutrition Metabolisms and Cancer, Service de Chirurgie Hépatobiliaire et Digestive, Biosit, Biogenouest, Core Facility H2P2 and CRB Santé Rennes France.

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March 2018

Post hoc analysis of plasma amino acid profiles: towards a specific pattern in autism spectrum disorder and intellectual disability.

Authors:

Jean-Baptiste Delaye Franck Patin Emmanuelle Lagrue Olivier Le Tilly Clement Bruno Marie-Laure Vuillaume Martine Raynaud Isabelle Benz-De Bretagne Frederic Laumonnier Patrick Vourc'h Christian Andres Helene Blasco

Ann Clin Biochem 2018 Sep 22;55(5):543-552. Epub 2018 Feb 22.

1 CHRU de Tours, Laboratoire de Biochimie et Biologie Moléculaire, Tours, France.

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September 2018

Local Anesthetics Inhibit the Growth of Human Hepatocellular Carcinoma Cells.

Authors:

Grégoire Le Gac Gaëlle Angenard Bruno Clément Bruno Laviolle Cédric Coulouarn Hélène Beloeil

Anesth Analg 2017 11;125(5):1600-1609

From the *INSERM, UMR 991, and Université de Rennes 1, Rennes, France; †CHU Rennes, Pôle Anesthésie et Réanimation, Inserm CIC 1414, Rennes, France; and ‡CHU Rennes, Clinical Pharmacology Department and Inserm CIC 1414, Université de Rennes 1, Rennes, France.

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November 2017