Publications Authored by Bruno Catalanotti

Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors.

Authors:

Alessandro Deplano Mariateresa Cipriano Federica Moraca Ettore Novellino Bruno Catalanotti Christopher J Fowler Valentina Onnis

J Enzyme Inhib Med Chem 2019 Dec;34(1):562-576

a Department of Life and Environmental Sciences - Unit of Pharmaceutical, Pharmacological and Nutraceutical Sciences , University of Cagliari , Cagliari , Italy.

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http://dx.doi.org/10.1080/14756366.2018.1532418	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352954	PMC

December 2019

Targeting multiple G-quadruplex-forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives.

Authors:

Raffaella Catalano Federica Moraca Jussara Amato Camilla Cristofari Riccardo Rigo Lisa Dalla Via Roberta Rocca Antonio Lupia Annalisa Maruca Giosuè Costa Bruno Catalanotti Anna Artese Bruno Pagano Antonio Randazzo Claudia Sissi Ettore Novellino Stefano Alcaro

Eur J Med Chem 2019 Aug 16;182:111627. Epub 2019 Aug 16.

Dipartimento di Scienze della Salute, Università "Magna Græcia", Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy; Net4Science srl, Università "Magna Græcia", Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy.

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http://dx.doi.org/10.1016/j.ejmech.2019.111627	DOI Listing

August 2019

Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.

Authors:

Laura Rinaldi Rossella Delle Donne Bruno Catalanotti Omar Torres-Quesada Florian Enzler Federica Moraca Robert Nisticò Francesco Chiuso Sonia Piccinin Verena Bachmann Herbert H Lindner Corrado Garbi Antonella Scorziello Nicola Antonino Russo Matthis Synofzik Ulrich Stelzl Lucio Annunziato Eduard Stefan Antonio Feliciello

Nat Commun 2019 06 12;10(1):2572. Epub 2019 Jun 12.

Department of Molecular Medicine and Medical Biotechnologies, University Federico II, 80131, Naples, Italy.

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http://dx.doi.org/10.1038/s41467-019-10037-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561907	PMC

June 2019

Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs.

Authors:

Stefano D'Errico Nicola Borbone Bruno Catalanotti Agnese Secondo Tiziana Petrozziello Ilaria Piccialli Anna Pannaccione Valeria Costantino Luciano Mayol Gennaro Piccialli Giorgia Oliviero

Mar Drugs 2018 Mar 10;16(3). Epub 2018 Mar 10.

SYSBIO, Centre of Systems Biology, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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http://dx.doi.org/10.3390/md16030089	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867633	PMC

March 2018

Novel propanamides as fatty acid amide hydrolase inhibitors.

Authors:

Alessandro Deplano Carmine Marco Morgillo Monica Demurtas Emmelie Björklund Mariateresa Cipriano Mona Svensson Sanaz Hashemian Giovanni Smaldone Emilia Pedone F Javier Luque Maria G Cabiddu Ettore Novellino Christopher J Fowler Bruno Catalanotti Valentina Onnis

Eur J Med Chem 2017 Aug 12;136:523-542. Epub 2017 May 12.

Department of Life and Environmental Sciences, Unit of Pharmaceutical, Pharmacological and Nutraceutical Sciences, University of Cagliari, via Ospedale 72, Cagliari I-09124, Italy.

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http://dx.doi.org/10.1016/j.ejmech.2017.05.033	DOI Listing

August 2017

Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis.

Authors:

Federica Zarrilli Felice Amato Carmine Marco Morgillo Brunella Pinto Giuliano Santarpia Nicola Borbone Stefano D'Errico Bruno Catalanotti Gennaro Piccialli Giuseppe Castaldo Giorgia Oliviero

Molecules 2017 Jul 8;22(7). Epub 2017 Jul 8.

Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, 80131 Napoli, Italy.

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http://dx.doi.org/10.3390/molecules22071144	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152032	PMC

July 2017

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.

Authors:

Simona De Marino Adriana Carino Dario Masullo Claudia Finamore Silvia Marchianò Sabrina Cipriani Francesco Saverio Di Leva Bruno Catalanotti Ettore Novellino Vittorio Limongelli Stefano Fiorucci Angela Zampella

Sci Rep 2017 02 24;7:43290. Epub 2017 Feb 24.

Department of Pharmacy, University of Naples "Federico II", Via D. Montesano, 49, I-80131 Naples, Italy.

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http://dx.doi.org/10.1038/srep43290	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324103	PMC

February 2017

Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode.

Authors:

Jessica Karlsson Carmine M Morgillo Alessandro Deplano Giovanni Smaldone Emilia Pedone F Javier Luque Mona Svensson Ettore Novellino Cenzo Congiu Valentina Onnis Bruno Catalanotti Christopher J Fowler

PLoS One 2015 13;10(11):e0142711. Epub 2015 Nov 13.

Department of Pharmacology and Clinical Neuroscience, Pharmacology Unit, Umeå University, Umeå, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142711	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643906	PMC

June 2016

Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin.

Authors:

Stefania Correale Ivan de Paola Carmine Marco Morgillo Antonella Federico Laura Zaccaro Pierlorenzo Pallante Aldo Galeone Alfredo Fusco Emilia Pedone F Javier Luque Bruno Catalanotti

PLoS One 2014 6;9(11):e112082. Epub 2014 Nov 6.

Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Napoli, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112082	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223017	PMC

July 2015

Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression.

Authors:

Felice Amato Rossella Tomaiuolo Fabrizia Nici Nicola Borbone Ausilia Elce Bruno Catalanotti Stefano D'Errico Carmine Marco Morgillo Giuseppe De Rosa Laura Mayol Gennaro Piccialli Giorgia Oliviero Giuseppe Castaldo

Biomed Res Int 2014 15;2014:610718. Epub 2014 Apr 15.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Via Pansini 5, 80131 Napoli, Italy ; CEINGE-Biotecnologie Avanzate, 80131 Napoli, Italy.

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http://dx.doi.org/10.1155/2014/610718	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009323	PMC

December 2014

Insight into the mechanism of action of plakortins, simple 1,2-dioxane antimalarials.

Authors:

Orazio Taglialatela-Scafati Ernesto Fattorusso Adriana Romano Fernando Scala Vincenzo Barone Paola Cimino Emiliano Stendardo Bruno Catalanotti Marco Persico Caterina Fattorusso

Org Biomol Chem 2010 Feb 16;8(4):846-56. Epub 2009 Dec 16.

Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli Federico II, Via D. Montesano 49, I-80131 Napoli, Italy.

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http://dx.doi.org/10.1039/b918600j	DOI Listing

February 2010

Full relative stereochemistry assignment and conformational analysis of 13,19-didesmethyl spirolide C via NMR- and molecular modeling-based techniques. A step towards understanding spirolide's mechanism of action.

Authors:

Patrizia Ciminiello Bruno Catalanotti Carmela Dell'aversano Caterina Fattorusso Ernesto Fattorusso Martino Forino Laura Grauso Angela Leo Luciana Tartaglione

Org Biomol Chem 2009 Sep 16;7(18):3674-81. Epub 2009 Jul 16.

Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli Federico II, via D. Montesano, 49, 80131 Napoli, Italy.

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http://dx.doi.org/10.1039/b907649b	DOI Listing

September 2009

Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.

J Med Chem 2009 Jun;52(11):3548-62

European Research Centre for Drug Discovery and Development, Siena, Italy.

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http://dx.doi.org/10.1021/jm900018b	DOI Listing

June 2009

Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.

Authors:

Stefania Butini Giuseppe Campiani Marianna Borriello Sandra Gemma Alessandro Panico Marco Persico Bruno Catalanotti Sindu Ros Margherita Brindisi Marianna Agnusdei Isabella Fiorini Vito Nacci Ettore Novellino Tatyana Belinskaya Ashima Saxena Caterina Fattorusso

J Med Chem 2008 Jun 15;51(11):3154-70. Epub 2008 May 15.

European Research Centre for Drug Discovery and Development (NatSynDrugs), Università di Siena, Siena, Italy.

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http://dx.doi.org/10.1021/jm701253t	DOI Listing

June 2008

Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.

Authors:

Sandra Gemma Gagan Kukreja Giuseppe Campiani Stefania Butini Matteo Bernetti Bhupendra P Joshi Luisa Savini Nicoletta Basilico Donatella Taramelli Vanessa Yardley Alessia Bertamino Ettore Novellino Marco Persico Bruno Catalanotti Caterina Fattorusso

Bioorg Med Chem Lett 2007 Jul 29;17(13):3535-9. Epub 2007 Apr 29.

European Research Centre for Drug Discovery & Development, Università di Siena, via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2007.04.077	DOI Listing

July 2007

Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore.

Authors:

Sandra Gemma Giuseppe Campiani Stefania Butini Gagan Kukreja Bhupendra P Joshi Marco Persico Bruno Catalanotti Ettore Novellino Ernesto Fattorusso Vito Nacci Luisa Savini Donatella Taramelli Nicoletta Basilico Giulia Morace Vanessa Yardley Caterina Fattorusso

J Med Chem 2007 Feb 31;50(4):595-8. Epub 2007 Jan 31.

Dipartimento Farmaco Chimico Tecnologico and European Research Centre for Drug Discovery and Development, Universita' di Siena, via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm061429p	DOI Listing

February 2007

Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents.

Authors:

Caterina Fattorusso Giuseppe Campiani Bruno Catalanotti Marco Persico Nicoletta Basilico Silvia Parapini Donatella Taramelli Claudio Campagnuolo Ernesto Fattorusso Adriana Romano Orazio Taglialatela-Scafati

J Med Chem 2006 Nov;49(24):7088-94

Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy.

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http://pubs.acs.org/doi/abs/10.1021/jm060899g	Publisher Site
http://dx.doi.org/10.1021/jm060899g	DOI Listing

November 2006

Discovery of huperzine A-tacrine hybrids as potent inhibitors of human cholinesterases targeting their midgorge recognition sites.

Authors:

Sandra Gemma Emanuele Gabellieri Paul Huleatt Caterina Fattorusso Marianna Borriello Bruno Catalanotti Stefania Butini Meri De Angelis Ettore Novellino Vito Nacci Tatyana Belinskaya Ashima Saxena Giuseppe Campiani

J Med Chem 2006 Jun;49(11):3421-5

Dipartimento Farmaco Chimico Tecnologico, Via Aldo Moro, Universita' di Siena, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm060257t	DOI Listing

June 2006

Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.

Authors:

Caterina Fattorusso Sandra Gemma Stefania Butini Paul Huleatt Bruno Catalanotti Marco Persico Meri De Angelis Isabella Fiorini Vito Nacci Anna Ramunno Manuela Rodriquez Giovanni Greco Ettore Novellino Alberto Bergamini Stefano Marini Massimo Coletta Giovanni Maga Silvio Spadari Giuseppe Campiani

J Med Chem 2005 Nov;48(23):7153-65

Dipartimento di Chimica delle Sostanze Naturali, Universita' di Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy.

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http://pubs.acs.org/doi/abs/10.1021/jm050257d	Publisher Site
http://dx.doi.org/10.1021/jm050257d	DOI Listing

November 2005

Pyrrolo[1,5]benzoxa(thia)zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target.

Authors:

Margaret M Mc Gee Sandra Gemma Stefania Butini Anna Ramunno Daniela M Zisterer Caterina Fattorusso Bruno Catalanotti Gagan Kukreja Isabella Fiorini Claudio Pisano Carla Cucco Ettore Novellino Vito Nacci D Clive Williams Giuseppe Campiani

J Med Chem 2005 Jun;48(13):4367-77

Department of Biochemistry, Trinity College, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/jm049402y	DOI Listing

June 2005

Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies.

Authors:

Giuseppe Campiani Stefania Butini Caterina Fattorusso Francesco Trotta Sandra Gemma Bruno Catalanotti Vito Nacci Isabella Fiorini Alfredo Cagnotto Ilario Mereghetti Tiziana Mennini Patrizia Minetti M Assunta Di Cesare M Antonietta Stasi Stefano Di Serio Orlando Ghirardi Ornella Tinti Paolo Carminati

J Med Chem 2005 Mar;48(6):1705-8

Dipartimento Farmaco Chimico Tecnologico, Via Aldo Moro, and European Research Centre for Drug Discovery and Development, Università di Siena, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm049629t	DOI Listing

March 2005

Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.

Authors:

Giuseppe Campiani Caterina Fattorusso Stefania Butini Alessandra Gaeta Marianna Agnusdei Sandra Gemma Marco Persico Bruno Catalanotti Luisa Savini Vito Nacci Ettore Novellino Harold W Holloway Nigel H Greig Tatyana Belinskaya James M Fedorko Ashima Saxena

J Med Chem 2005 Mar;48(6):1919-29

Dipartimento Farmaco Chimico Tecnologico, via Aldo Moro, and European Research Centre for Drug Discovery and Development (NatSynDrugs), Università di Siena, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm049510k	DOI Listing

March 2005

Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.

Authors:

David G Lloyd Rosario B Hughes Daniela M Zisterer D Clive Williams Caterina Fattorusso Bruno Catalanotti Giuseppe Campiani Mary J Meegan

J Med Chem 2004 Nov;47(23):5612-5

Department of Biochemistry, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/jm0495834	DOI Listing

November 2004

Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.

J Med Chem 2004 Jan;47(1):143-57

Dipartimento Farmaco Chimico Tecnologico, Via Aldo Moro and European Research Centre for Drug Discovery and Development, Universitá degli Studi di Siena, 53100 Siena, Italy.

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http://pubs.acs.org/doi/abs/10.1021/jm0309811	Publisher Site
http://dx.doi.org/10.1021/jm0309811	DOI Listing

January 2004

Oligonucleotides containing an acridine group covalently bonded to the nucleotide flanking the 3'-3' phosphodiester junction for alternate strand triple helix formation.

Authors:

Bruno Catalanotti Caterina Fattorusso Luciano Mayol Giorgia Oliviero Gennaro Piccialli Michela Varra

Nucleosides Nucleotides Nucleic Acids 2003 May-Aug;22(5-8):1069-71

Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli Federico II, Napoli, Italy.

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http://dx.doi.org/10.1081/NCN-120022738	DOI Listing

December 2003

Substrate inhibitors and blockers of excitatory amino acid transporters in the treatment of neurodegeneration: critical considerations.

Authors:

Tiziana Mennini Elena Fumagalli Marco Gobbi Caterina Fattorusso Bruno Catalanotti Giuseppe Campiani

Eur J Pharmacol 2003 Oct;479(1-3):291-6

Laboratory Receptor Pharmacology, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157, Milan, Italy.

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http://dx.doi.org/10.1016/j.ejphar.2003.08.078	DOI Listing

October 2003

Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases.

Authors:

Giuseppe Campiani Caterina Fattorusso Meri De Angelis Bruno Catalanotti Stefania Butini Roberto Fattorusso Isabella Fiorini Vito Nacci Ettore Novellino

Curr Pharm Des 2003 ;9(8):599-625

Dipartimento Farmaco Chimico Tecnologico (DFCT), Universita' degli Studi di Siena, via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.2174/1381612033391261	DOI Listing

August 2003

Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.

Authors:

Giuseppe Campiani Stefania Butini Francesco Trotta Caterina Fattorusso Bruno Catalanotti Francesca Aiello Sandra Gemma Vito Nacci Ettore Novellino Jennifer Ann Stark Alfredo Cagnotto Elena Fumagalli Francesco Carnovali Luigi Cervo Tiziana Mennini

J Med Chem 2003 Aug;46(18):3822-39

Dipartimento Farmaco Chimico Tecnologico, Universitá di Siena, via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm0211220	DOI Listing

August 2003

Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors.

Authors:

Luisa Savini Alessandra Gaeta Caterina Fattorusso Bruno Catalanotti Giuseppe Campiani Luisa Chiasserini Cesare Pellerano Ettore Novellino Dawn McKissic Ashima Saxena

J Med Chem 2003 Jan;46(1):1-4

Dipartimento Farmaco Chimico Tecnologico, Università di Siena, via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm0255668	DOI Listing

January 2003

Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives.

Authors:

Giuseppe Campiani Anna Ramunno Giovanni Maga Vito Nacci Caterina Fattorusso Bruno Catalanotti Elena Morelli Ettore Novellino

Curr Pharm Des 2002 ;8(8):615-57

Dipartimento Farmaco Chimico Tecnologico, Universitá degli Studi di Siena, via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.2174/1381612024607207	DOI Listing

July 2002

Circular dichroism and thermal melting differentiation of Hoechst 33258 binding to the curved (A(4)T(4)) and straight (T(4)A(4)) DNA sequences.

Authors:

Claudia Canzonetta Roberto Caneva Maria Savino Anita Scipioni Bruno Catalanotti Aldo Galeone

Biochim Biophys Acta 2002 Jun;1576(1-2):136-42

Centro di Studio per gli Acidi Nucleici del CNR, c/o Dipartimento di Genetica e Biologia Molecolare, Università di Roma La Sapienza, Piazzale Aldo Moro. 5, 00185 Rome, Italy.

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http://dx.doi.org/10.1016/s0167-4781(02)00338-x	DOI Listing

June 2002

Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.

J Med Chem 2002 Jan;45(2):344-59

Dipartimento Farmaco Chimico Tecnologico, Universitá degli Studi di Siena, Via Aldo Moro, 53100 Siena, Italy.

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http://dx.doi.org/10.1021/jm010982y	DOI Listing

January 2002

Bruno Catalanotti

Bruno Catalanotti

Publications by authors named "Bruno Catalanotti"

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