Bruno Bulic

Bruno Bulic

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Bruno Bulic

Bruno Bulic

Publications by authors named "Bruno Bulic"

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Progress and developments in tau aggregation inhibitors for Alzheimer disease.

J Med Chem 2013 Jun 13;56(11):4135-55. Epub 2013 Mar 13.

Laboratory of Organic Synthesis of Functional Systems, Humboldt-Universität zu Berlin, Brook-Taylor-Strasse 2, 12489 Berlin, Germany.

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http://pubs.acs.org/doi/10.1021/jm3017317
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http://dx.doi.org/10.1021/jm3017317DOI Listing
June 2013

Synthesis of a potent photoreactive acidic γ-secretase modulator for target identification in cells.

Bioorg Med Chem 2012 Nov 31;20(21):6523-32. Epub 2012 Aug 31.

Research Group Chemical Biology of Neurodegenerative Diseases, Center of Advanced European Studies and Research, Ludwig-Erhard-Allee 2, D-53175 Bonn, Germany.

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http://dx.doi.org/10.1016/j.bmc.2012.08.034DOI Listing
November 2012

Discovery of γ-secretase modulators with a novel activity profile by text-based virtual screening.

ACS Chem Biol 2012 Sep 2;7(9):1488-95. Epub 2012 Jul 2.

Department of Neuropathology, Heinrich-Heine-University, D-40225 Duesseldorf, Germany.

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http://dx.doi.org/10.1021/cb3001952DOI Listing
September 2012

No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease.

Neurobiol Aging 2012 Apr 22;33(4):833.e39-50. Epub 2011 Sep 22.

Division of Molecular Psychiatry and Alzheimer Ph.D. Graduate School, Department of Psychiatry, University Medicine Goettingen, Goettingen, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2011.08.006DOI Listing
April 2012

Chemical Biology, Molecular Mechanism and Clinical Perspective of γ-Secretase Modulators in Alzheimer's Disease.

Curr Neuropharmacol 2011 Dec;9(4):598-622

Research Group Chemical Biology of Neurodegenerative Diseases, Center of Advanced European Studies and Research, D-53175 Bonn, Germany.

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http://dx.doi.org/10.2174/157015911798376352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391656PMC
December 2011

Tau protein and tau aggregation inhibitors.

Neuropharmacology 2010 Sep-Oct;59(4-5):276-89. Epub 2010 Feb 10.

Center for Advanced European Studies and Research, Bonn, Germany.

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http://dx.doi.org/10.1016/j.neuropharm.2010.01.016DOI Listing
June 2011

Development of tau aggregation inhibitors for Alzheimer's disease.

Angew Chem Int Ed Engl 2009 ;48(10):1740-52

Max-Planck-Institute for Molecular Physiology, Dortmund, Germany.

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http://dx.doi.org/10.1002/anie.200802621DOI Listing
April 2009

Small-molecule inhibitors of islet amyloid polypeptide fibril formation.

Angew Chem Int Ed Engl 2008 ;47(25):4679-82

Faculty of Chemistry, Physical Chemistry I-Biophysical Chemistry, Technical University Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.

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http://doi.wiley.com/10.1002/anie.200705372
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http://dx.doi.org/10.1002/anie.200705372DOI Listing
August 2008

Rhodanine-based tau aggregation inhibitors in cell models of tauopathy.

Angew Chem Int Ed Engl 2007 ;46(48):9215-9

Max-Planck-Institute for Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://dx.doi.org/10.1002/anie.200704051DOI Listing
February 2008