Bruce S Kristal

Bruce S Kristal

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Bruce S Kristal

Publications by authors named "Bruce S Kristal"

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Posterior Cervical Keyhole Laminoforaminotomy: A Cadaveric Comparative Study to Evaluate Limits of Bony Resection.

Oper Neurosurg (Hagerstown) 2019 May;16(5):607-613

Department of Neurosurgery, Medical Park Goztepe Hospital, Bahcesehir University School of Medicine, Istanbul, Turkey.

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http://dx.doi.org/10.1093/ons/opy230DOI Listing
May 2019

Mitochondria modulate programmed neuritic retraction.

Proc Natl Acad Sci U S A 2019 01 24;116(2):650-659. Epub 2018 Dec 24.

Neuroapoptosis Laboratory, Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213;

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http://dx.doi.org/10.1073/pnas.1811021116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329959PMC
January 2019

Optimization of Electrospray Ionization Source Parameters for Lipidomics To Reduce Misannotation of In-Source Fragments as Precursor Ions.

Anal Chem 2018 11 2;90(22):13523-13532. Epub 2018 Nov 2.

Department of Medicine , Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, and Department of Medicine, Division of Sleep Medicine, Harvard Medical School , Boston , Massachusetts 02115 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b03436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297073PMC
November 2018

The integration of LC-MS and NMR for the analysis of low molecular weight trace analytes in complex matrices.

Mass Spectrom Rev 2018 Jul 19. Epub 2018 Jul 19.

Barnett Institute of Chemical and Biological Analysis and Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts.

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http://dx.doi.org/10.1002/mas.21575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339611PMC
July 2018

Simple LC-MS Method for Differentiation of Isobaric Phosphatidylserines and Phosphatidylcholines with Deuterated Mobile Phase Additives.

Anal Chem 2016 09 26;88(18):9103-10. Epub 2016 Aug 26.

Department of Medicine, Division of Sleep Medicine and Circadian Disorders, Harvard Medical School , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b02063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045954PMC
September 2016

Surgical injury induces local and distant adipose tissue browning.

Adipocyte 2016 Apr-Jun;5(2):163-74. Epub 2015 Nov 20.

Department of Surgery and the Heart and Vascular Center, Brigham and Women's Hospital/Harvard Medical School , Boston, MA, USA.

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http://dx.doi.org/10.1080/21623945.2015.1111971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916868PMC
July 2016

Preoperative dietary restriction reduces intimal hyperplasia and protects from ischemia-reperfusion injury.

J Vasc Surg 2016 Feb 8;63(2):500-9.e1. Epub 2014 Aug 8.

Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jvs.2014.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320991PMC
February 2016

Adipose phenotype predicts early human autogenous arteriovenous hemodialysis remodeling.

J Vasc Surg 2016 Jan 26;63(1):171-6.e1. Epub 2014 Sep 26.

Department of Surgery, Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jvs.2014.06.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377114PMC
January 2016

N-acetyl-L-tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model.

Neurobiol Dis 2015 Aug 16;80:93-103. Epub 2015 May 16.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.05.002DOI Listing
August 2015

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.

Authors:
Marilyn C Cornelis Enda M Byrne Tõnu Esko Michael A Nalls Andrea Ganna Nina Paynter Keri L Monda Najaf Amin Krista Fischer Frida Renstrom Julius S Ngwa Ville Huikari Alana Cavadino Ilja M Nolte Alexander Teumer Kai Yu Pedro Marques-Vidal Rajesh Rawal Ani Manichaikul Mary K Wojczynski Jacqueline M Vink Jing Hua Zhao George Burlutsky Jari Lahti Vera Mikkilä Rozenn N Lemaitre Joel Eriksson Solomon K Musani Toshiko Tanaka Frank Geller Jian'an Luan Jennie Hui Reedik Mägi Maria Dimitriou Melissa E Garcia Weang-Kee Ho Margaret J Wright Lynda M Rose Patrik Ke Magnusson Nancy L Pedersen David Couper Ben A Oostra Albert Hofman Mohammad Arfan Ikram Henning W Tiemeier Andre G Uitterlinden Frank Ja van Rooij Inês Barroso Ingegerd Johansson Luting Xue Marika Kaakinen Lili Milani Chris Power Harold Snieder Ronald P Stolk Sebastian E Baumeister Reiner Biffar Fangyi Gu François Bastardot Zoltán Kutalik David R Jacobs Nita G Forouhi Evelin Mihailov Lars Lind Cecilia Lindgren Karl Michaëlsson Andrew Morris Majken Jensen Kay-Tee Khaw Robert N Luben Jie Jin Wang Satu Männistö Mia-Maria Perälä Mika Kähönen Terho Lehtimäki Jorma Viikari Dariush Mozaffarian Kenneth Mukamal Bruce M Psaty Angela Döring Andrew C Heath Grant W Montgomery Norbert Dahmen Teresa Carithers Katherine L Tucker Luigi Ferrucci Heather A Boyd Mads Melbye Jorien L Treur Dan Mellström Jouke Jan Hottenga Inga Prokopenko Anke Tönjes Panos Deloukas Stavroula Kanoni Mattias Lorentzon Denise K Houston Yongmei Liu John Danesh Asif Rasheed Marc A Mason Alan B Zonderman Lude Franke Bruce S Kristal Juha Karjalainen Danielle R Reed Harm-Jan Westra Michele K Evans Danish Saleheen Tamara B Harris George Dedoussis Gary Curhan Michael Stumvoll John Beilby Louis R Pasquale Bjarke Feenstra Stefania Bandinelli Jose M Ordovas Andrew T Chan Ulrike Peters Claes Ohlsson Christian Gieger Nicholas G Martin Melanie Waldenberger David S Siscovick Olli Raitakari Johan G Eriksson Paul Mitchell David J Hunter Peter Kraft Eric B Rimm Dorret I Boomsma Ingrid B Borecki Ruth Jf Loos Nicholas J Wareham Peter Vollenweider Neil Caporaso Hans Jörgen Grabe Marian L Neuhouser Bruce Hr Wolffenbuttel Frank B Hu Elina Hyppönen Marjo-Riitta Järvelin L Adrienne Cupples Paul W Franks Paul M Ridker Cornelia M van Duijn Gerardo Heiss Andres Metspalu Kari E North Erik Ingelsson Jennifer A Nettleton Rob M van Dam Daniel I Chasman

Mol Psychiatry 2015 May 7;20(5):647-656. Epub 2014 Oct 7.

Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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https://handls.nih.gov/pubs/2015-Coffee-MolPsychiatry-20-647
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http://www.nature.com/doifinder/10.1038/mp.2014.107
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http://dx.doi.org/10.1038/mp.2014.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388784PMC
May 2015

Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction.

J Biol Chem 2014 Aug 18;289(31):21490-507. Epub 2014 Jun 18.

From the Center for Neurologic Diseases, Department of Neurology, and

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http://dx.doi.org/10.1074/jbc.M113.545749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118111PMC
August 2014

Identification of metabolites from liquid chromatography-coulometric array detection profiling: gas chromatography-mass spectrometry and refractionation provide essential information orthogonal to LC-MS/microNMR.

Anal Biochem 2014 Jun 18;454:23-32. Epub 2014 Mar 18.

Department of Neurosurgery, Brigham and Women's Hospital, Department of Neurosurgery, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2014.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034759PMC
June 2014

N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.

J Neurosci 2014 Feb;34(8):2967-78

Departments of Neurosurgery, Surgery, and Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, Department of Neurosurgery, Remin Hospital of Wuhan Univerisity, Wuhan, Hubei 430060, China, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, and Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213.

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http://dx.doi.org/10.1523/JNEUROSCI.1948-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929763PMC
February 2014

Dietary macronutrients modulate the fatty acyl composition of rat liver mitochondrial cardiolipins.

J Lipid Res 2013 Oct 20;54(10):2623-35. Epub 2013 May 20.

Department of Neurosurgery, Brigham and Women's Hospital, Department of Surgery, Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1194/jlr.M036285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770076PMC
October 2013

Qualitative Characterization of the Rat Liver Mitochondrial Lipidome using LC-MS Profiling and High Energy Collisional Dissociation (HCD) All Ion Fragmentation.

Metabolomics 2013 Mar;9(1 Suppl):67-83

Department of Neurosurgery, Brigham and Women's Hospital and, Department of Surgery, Harvard Medical School, 221 Longwood Avenue, LMRC-322, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1007/s11306-012-0400-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640281PMC
March 2013

Method development for fecal lipidomics profiling.

Anal Chem 2013 Jan 26;85(2):1114-23. Epub 2012 Dec 26.

Boston College, W.F. Connell School of Nursing, 140 Commonwealth Avenue, Chestnut Hill, Massachusetts 02467, USA.

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http://dx.doi.org/10.1021/ac303011kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928122PMC
January 2013

Structural characterization of plasma metabolites detected via LC-electrochemical coulometric array using LC-UV fractionation, MS, and NMR.

Anal Chem 2012 Nov 6;84(22):9889-98. Epub 2012 Nov 6.

Department of Neurosurgery, Brigham and Women's Hospital, and Harvard Medical School, 221 Longwood Avenue, LMRC-322, Boston, Massachusetts 02115, United States.

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http://pubs.acs.org/doi/10.1021/ac302278u
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http://dx.doi.org/10.1021/ac302278uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502645PMC
November 2012

Dietary Omega-3 Fatty Acids Do Not Change Resistance of Rat Brain or Liver Mitochondria to Ca(2+) and/or Prooxidants.

J Lipids 2012 27;2012:797105. Epub 2012 Aug 27.

Department of Neurosurgery, Brigham and Women's Hospital, 221 Longwood Avenue, Room LM322, Boston, MA 02115, USA.

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http://www.hindawi.com/journals/jl/2012/797105/
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http://dx.doi.org/10.1155/2012/797105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434410PMC
September 2012

The use of underloaded C(18) solid-phase extraction plates increases reproducibility of analysis of tryptic peptides from unfractionated human plasma.

Anal Biochem 2012 Jul 7;426(1):86-90. Epub 2012 Apr 7.

Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ab.2012.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369824PMC
July 2012

Separation of cis-trans phospholipid isomers using reversed phase LC with high resolution MS detection.

Anal Chem 2012 Jul 12;84(13):5509-17. Epub 2012 Jun 12.

Department of Neurosurgery, Brigham and Women's Hospital, Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/ac300953jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397781PMC
July 2012

LigSeeSVM: ligand-based virtual screening using support vector machines and data fusion.

Int J Comput Biol Drug Des 2011 21;4(3):274-89. Epub 2011 Jul 21.

Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30050, Taiwan.

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http://dx.doi.org/10.1504/IJCBDD.2011.041415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928123PMC
November 2011

The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity.

J Neurosci 2011 Oct;31(41):14496-507

Neuroapoptosis Laboratory and Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3059-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213696PMC
October 2011

Serum lipidomics profiling using LC-MS and high-energy collisional dissociation fragmentation: focus on triglyceride detection and characterization.

Anal Chem 2011 Sep 5;83(17):6648-57. Epub 2011 Aug 5.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, LMRC-322, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1021/ac201195dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165109PMC
September 2011

Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: focus on characterization of mitochondrial cardiolipins and monolysocardiolipins.

Anal Chem 2011 Feb 30;83(3):940-9. Epub 2010 Dec 30.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1021/ac102598uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031668PMC
February 2011

Reactive gamma-ketoaldehydes formed via the isoprostane pathway disrupt mitochondrial respiration and calcium homeostasis.

Free Radic Biol Med 2010 Aug 2;49(4):567-79. Epub 2010 Jun 2.

Department of Neurosurgery, Brigham and Women's Hospital, 221 Longwood Avenue, Room LM322, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.04.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903647PMC
August 2010

Methazolamide and melatonin inhibit mitochondrial cytochrome C release and are neuroprotective in experimental models of ischemic injury.

Stroke 2009 May 19;40(5):1877-85. Epub 2009 Mar 19.

Department of Neurosurgery, Neuroapoptosis Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1161/STROKEAHA.108.540765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674528PMC
May 2009

Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease.

J Neurosci 2008 Sep;28(38):9473-85

Neuroapoptosis Laboratory and Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1867-08.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632939PMC
September 2008

Metabolite identification using a nanoelectrospray LC-EC-array-MS integrated system.

Anal Chem 2008 Aug 25;80(15):5912-23. Epub 2008 Jun 25.

Barnett Institute and Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1021/ac800507yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657231PMC
August 2008

Metabolomics: a global biochemical approach to drug response and disease.

Annu Rev Pharmacol Toxicol 2008 ;48:653-83

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.pharmtox.48
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http://dx.doi.org/10.1146/annurev.pharmtox.48.113006.094715DOI Listing
March 2008

Nortriptyline protects mitochondria and reduces cerebral ischemia/hypoxia injury.

Stroke 2008 Feb 3;39(2):455-62. Epub 2008 Jan 3.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, LMRC 113, Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/STROKEAHA.107.496810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632945PMC
February 2008

Kinetic model for Ca2+-induced permeability transition in energized liver mitochondria discriminates between inhibitor mechanisms.

J Biol Chem 2008 Jan 25;283(2):665-76. Epub 2007 Oct 25.

Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M703484200
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http://dx.doi.org/10.1074/jbc.M703484200DOI Listing
January 2008

Effect of vitamin C supplementation on stroke recovery: a case-control study.

Clin Interv Aging 2007 ;2(1):147-51

Burke Rehabilitation Hospital, an affiliate of Weill Medical College of Cornell Medical College, 785 Mamaroneck Avenue, White Plains, NY 10605, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684077PMC
January 2008

Biological variability dominates and influences analytical variance in HPLC-ECD studies of the human plasma metabolome.

BMC Clin Pathol 2007 Nov 12;7. Epub 2007 Nov 12.

Department of Neurosurgery, Brigham and Women's Hospital, 221 Longwood Ave, LM322B, Boston, MA 02115, USA.

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http://bmcclinpathol.biomedcentral.com/articles/10.1186/1472
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http://dx.doi.org/10.1186/1472-6890-7-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2203971PMC
November 2007

Metabolomics in the study of aging and caloric restriction.

Methods Mol Biol 2007 ;371:393-409

Dementia Research Service, Burke Medical Research Institute, White Plains and Department of Neuroscience, Weill Medical College of Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-59745-361-5_25DOI Listing
September 2007

Increased stem cell proliferation in the spinal cord of adult amyotrophic lateral sclerosis transgenic mice.

J Neurochem 2007 Aug 30;102(4):1125-38. Epub 2007 Apr 30.

Neuroapoptosis Laboratory, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04610.xDOI Listing
August 2007

Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition.

J Biol Chem 2007 Aug 12;282(33):24373-80. Epub 2007 Jun 12.

Burke Medical Research Institute, White Plains, New York 10605, USA.

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http://dx.doi.org/10.1074/jbc.M611376200DOI Listing
August 2007

Nortriptyline delays disease onset in models of chronic neurodegeneration.

Eur J Neurosci 2007 Aug;26(3):633-41

Neuroapoptosis Laboratory, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, LMRC 113, Boston, MA 02115, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2007.05663.xDOI Listing
August 2007

Branched chain keto-acids exert biphasic effects on alpha-ketoglutarate-stimulated respiration in intact rat liver mitochondria.

Neurochem Res 2007 Apr-May;32(4-5):947-51. Epub 2007 Mar 7.

Dementia Research Service, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA.

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http://link.springer.com/10.1007/s11064-007-9291-3
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http://dx.doi.org/10.1007/s11064-007-9291-3DOI Listing
May 2007

High-performance liquid chromatography separations coupled with coulometric electrode array detectors: a unique approach to metabolomics.

Methods Mol Biol 2007 ;358:159-74

Dementia Research Service, Burke Medical Research Institute, White Plains, NY, USA.

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http://dx.doi.org/10.1007/978-1-59745-244-1_10DOI Listing
January 2007

Consensus scoring criteria for improving enrichment in virtual screening.

J Chem Inf Model 2005 Jul-Aug;45(4):1134-46

Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30050, Taiwan.

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http://gemdock.life.nctu.edu.tw/dock/download/Selected_Ref/J
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https://pdfs.semanticscholar.org/8891/97289c8464b956714beccc
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http://pubs.acs.org/doi/abs/10.1021/ci050034w
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http://dx.doi.org/10.1021/ci050034wDOI Listing
May 2006

Comparative kinetic analysis reveals that inducer-specific ion release precedes the mitochondrial permeability transition.

Biochim Biophys Acta 2005 Jul;1708(3):375-92

Dementia Research Service, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA.

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http://dx.doi.org/10.1016/j.bbabio.2005.05.009DOI Listing
July 2005

Metabolomics: opening another window into aging.

Sci Aging Knowledge Environ 2005 Jun 29;2005(26):pe19. Epub 2005 Jun 29.

Dementia Research Service, Burke Medical Research Institute, White Plains, NY 10605, USA.

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http://dx.doi.org/10.1126/sageke.2005.26.pe19DOI Listing
June 2005

pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification.

J Biol Chem 2005 Apr 14;280(16):16106-14. Epub 2005 Feb 14.

Department of Chemical Enzymology, M. V. Lomonosov Moscow State University, 119899 Moscow, Russia.

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http://dx.doi.org/10.1074/jbc.M414285200DOI Listing
April 2005

The powerhouse takes control of the cell: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?

Free Radic Biol Med 2005 Mar;38(6):687-97

Dementia Research Service, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490400966
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http://dx.doi.org/10.1016/j.freeradbiomed.2004.11.032DOI Listing
March 2005

Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

Proc Natl Acad Sci U S A 2005 Feb 3;102(7):2602-7. Epub 2005 Feb 3.

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.0409402102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548984PMC
February 2005

Promethazine: a novel application as a neuroprotectant that reduces ischemia-mediated injury by inhibiting mitochondrial dysfunction.

Clin Neurosurg 2004 ;51:102-7

Department of Neurosurgery, Brigham and Women's Hospital, Harvard University Medical School, Boston, Massachusetts, USA.

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January 2005

Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice.

J Neurosci 2004 Jun;24(26):5909-12

Neuroapoptosis Laboratory, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1278-04.2004DOI Listing
June 2004

Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase.

Neurobiol Dis 2004 Apr;15(3):610-7

Department of Neurology and Neuroscience, New York-Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.nbd.2003.12.014DOI Listing
April 2004

Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases.

Neurotoxicology 2004 Jan;25(1-2):101-15

Department of Neurology, Veterans Affairs Medical Center, Saint Louis University Health Sciences Center, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/S0161-813X(03)00090-1DOI Listing
January 2004

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease.

Proc Natl Acad Sci U S A 2003 Sep 20;100(18):10483-7. Epub 2003 Aug 20.

Neuroapoptosis Laboratory, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1832501100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193587PMC
September 2003

Simultaneous analysis of multiple redox-active metabolites from biological matrices.

Methods Mol Biol 2002 ;186:185-94

Departments of Biochemistry and Neuroscience, Burke Medical Research Institute, Weill Medical College of Cornell University and Dementia Research Service, White Plains, NY, USA.

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http://dx.doi.org/10.1385/1-59259-173-6:185DOI Listing
August 2003

Caloric restriction in trans.

Sci Aging Knowledge Environ 2003 Jul 9;2003(27):PE19. Epub 2003 Jul 9.

Dementia Research Service, Burke Medical Research Institute, White Plains, NY 10605, USA.

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July 2003

Structure-(Dys)function relationships in mitochondrial electron transport chain complex II?

Sci Aging Knowledge Environ 2003 Feb 5;2003(5):PE3. Epub 2003 Feb 5.

Dementia Research Service of the Burke Medical Research Institute, White Plains, NY 10605, USA.

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February 2003

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice.

Nature 2002 May;417(6884):74-8

Neuroapoptosis Laboratory, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/417074aDOI Listing
May 2002

Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase.

J Biol Chem 2002 Mar 13;277(12):10064-72. Epub 2001 Dec 13.

Burke Medical Research Institute, Weill Medical College of Cornell University, White Plains, New York 10605, USA.

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http://dx.doi.org/10.1074/jbc.M108264200DOI Listing
March 2002

Attention to relative response across sequential electrodes improves quantitation of coulometric array.

Anal Biochem 2002 Mar;302(2):239-45

Dementia Research Service, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, New York 10605, USA.

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http://dx.doi.org/10.1006/abio.2001.5568DOI Listing
March 2002