Bruce R Blazar

Bruce R Blazar

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Bruce R Blazar

Publications by authors named "Bruce R Blazar"

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Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses.

Nat Immunol 2019 Oct 2;20(10):1360-1371. Epub 2019 Sep 2.

Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41590-019-0472-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754271PMC
October 2019

Pediatric acute GVHD: clinical phenotype and response to upfront steroids.

Bone Marrow Transplant 2019 Sep 2. Epub 2019 Sep 2.

Blood and Marrow Transplant Program, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41409-019-0651-9
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http://dx.doi.org/10.1038/s41409-019-0651-9DOI Listing
September 2019

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.

Immunity 2019 Sep 18. Epub 2019 Sep 18.

Bone Marrow Transplantation Laboratory, Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia; Department of Haematology and Bone Marrow Transplantation, Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Division of Medical Oncology, University of Washington, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.08.011DOI Listing
September 2019

Outcomes and Predictors of Response in Steroid-Refractory Acute Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2019 Jul 17. Epub 2019 Jul 17.

Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2019.07.017DOI Listing
July 2019

Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets.

PLoS One 2019 6;14(6):e0217761. Epub 2019 Jun 6.

Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217761PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553739PMC
June 2019

Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming.

J Clin Invest 2019 Jun 18;130:3770-3785. Epub 2019 Jun 18.

Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1172/JCI125916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715389PMC
June 2019

TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination.

EMBO J 2019 May 18;38(9). Epub 2019 Mar 18.

Translational Medicine Research Center of Affiliated Jiangning Hospital, Liver Transplantation Center of First Affiliated Hospital, and Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing, Jiangsu, China

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http://dx.doi.org/10.15252/embj.201899766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484404PMC
May 2019

Analysis of BMT CTN-0201 and -0901 samples did not reproduce the reported association between recipient REG3A rs7588571 and chronic GVHD.

Bone Marrow Transplant 2019 Mar 31;54(3):490-493. Epub 2018 Aug 31.

Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41409-018-0331-1
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http://dx.doi.org/10.1038/s41409-018-0331-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395530PMC
March 2019

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program.

J Exp Med 2019 Mar 31;216(3):605-620. Epub 2019 Jan 31.

Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1084/jem.20181134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400538PMC
March 2019

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth.

Cancer Gene Ther 2019 Mar 1. Epub 2019 Mar 1.

Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.1038/s41417-019-0089-7DOI Listing
March 2019

Achievement of Tolerance Induction to Prevent Acute Graft-vs.-Host Disease.

Front Immunol 2019 6;10:309. Epub 2019 Mar 6.

Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00309
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http://dx.doi.org/10.3389/fimmu.2019.00309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419712PMC
March 2019

Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease.

Front Immunol 2018 31;9:57. Epub 2018 Jan 31.

Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota Cancer Center, Minneapolis, MN, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797736PMC
February 2019

Reduction in murine acute GVHD severity by human gingival tissue-derived mesenchymal stem cells via the CD39 pathways.

Cell Death Dis 2019 01 8;10(1):13. Epub 2019 Jan 8.

Hepatobiliary Center, First Affiliated Hospital, Jiangsu Key Laboratory of Xenotransplantation, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, 211166, Nanjing, Jiangsu, China.

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http://www.nature.com/articles/s41419-018-1273-7
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http://dx.doi.org/10.1038/s41419-018-1273-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325106PMC
January 2019

Thymic Epithelial Cell Support of Thymopoiesis Does Not Require .

J Immunol 2018 12 29;201(11):3320-3328. Epub 2018 Oct 29.

Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1800670
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http://dx.doi.org/10.4049/jimmunol.1800670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275142PMC
December 2018

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.

Cell 2018 12 1;175(7):1780-1795.e19. Epub 2018 Nov 1.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Immunobiology, Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183130
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http://dx.doi.org/10.1016/j.cell.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361668PMC
December 2018

C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans.

JCI Insight 2018 12 20;3(24). Epub 2018 Dec 20.

Department of Medicine, Translational Transplant Research Center, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1172/jci.insight.124646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338317PMC
December 2018

Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2018 11 7;24(11):2190-2196. Epub 2018 Jul 7.

Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791183038
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http://dx.doi.org/10.1016/j.bbmt.2018.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251308PMC
November 2018

Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets.

J Immunol 2018 10 12;201(8):2215-2219. Epub 2018 Sep 12.

Department of Surgery and Center for Transplantation Sciences; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129;

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http://dx.doi.org/10.4049/jimmunol.1800311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179917PMC
October 2018

Association between recipient TNF rs361525 and acute GVHD: results from analysis of BMT CTN-0201 samples.

Bone Marrow Transplant 2018 08 7;53(8):1069-1071. Epub 2018 Mar 7.

Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1038/s41409-018-0127-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064382PMC
August 2018

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death.

Cell Metab 2018 08 7;28(2):228-242.e6. Epub 2018 Jun 7.

Georgia Cancer Center, Medical College of Georgia, Augusta University, 1120 15(th) Street, CN-4140, Augusta, GA 30912, USA; Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082691PMC
August 2018

Maintenance of CD4 T cell fitness through regulation of Foxo1.

Nat Immunol 2018 08 9;19(8):838-848. Epub 2018 Jul 9.

Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41590-018-0157-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289177PMC
August 2018

How ibrutinib, a B-cell malignancy drug, became an FDA-approved second-line therapy for steroid-resistant chronic GVHD.

Blood Adv 2018 08;2(15):2012-2019

Division of Blood and Marrow Transplantation, Department of Pediatrics, The University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1182/bloodadvances.2018013060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093735PMC
August 2018

A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression.

PLoS One 2018 4;13(4):e0193461. Epub 2018 Apr 4.

Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193461PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884478PMC
July 2018

Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37.

Cancer Immunol Res 2018 07 21;6(7):766-775. Epub 2018 May 21.

Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030483PMC
July 2018

Immune regulatory cell infusion for graft-versus-host disease prevention and therapy.

Blood 2018 06 4;131(24):2651-2660. Epub 2018 May 4.

Bone Marrow Transplantation Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia; and.

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http://dx.doi.org/10.1182/blood-2017-11-785865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032895PMC
June 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells.

Biol Blood Marrow Transplant 2018 03 29;24(3):618-622. Epub 2017 Nov 29.

Pediatric Hematology/Oncology/Bone Marrow Transplant, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826878PMC
March 2018

Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells.

Cancer Immunol Immunother 2018 Mar 7;67(3):483-494. Epub 2017 Dec 7.

Blood and Marrow Transplant Program, University of Minnesota, MMC 480, 420 Delaware Street, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1007/s00262-017-2100-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055922PMC
March 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

B-cell targeting in chronic graft-versus-host disease.

Blood 2018 03 1;131(13):1399-1405. Epub 2018 Feb 1.

Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1182/blood-2017-11-784017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031308PMC
March 2018

CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression.

Int J Mol Sci 2018 Mar 22;19(4). Epub 2018 Mar 22.

Department of Pediatrics, Division of Blood and Marrow Transplantation, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.3390/ijms19040946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979553PMC
March 2018

Acute Graft-versus-Host Disease.

N Engl J Med 2018 02;378(6):586

University of Minnesota, Minneapolis, MN

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http://dx.doi.org/10.1056/NEJMc1716969DOI Listing
February 2018

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg).

Cell Death Dis 2018 02 19;9(3):290. Epub 2018 Feb 19.

Liver Transplantation Center, First Affiliated Hospital, Nanjing Medical University, No. 300 Guangzhou Road, Jiangsu Province, Nanjing, 210029, China.

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http://dx.doi.org/10.1038/s41419-018-0298-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833855PMC
February 2018

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6cCD103 Monocytic Antigen-Presenting Cells in Tumors.

Immunity 2018 01;48(1):91-106.e6

Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Department of Pediatrics, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005382PMC
January 2018

B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.

J Immunol 2017 12 1;199(12):3972-3980. Epub 2017 Nov 1.

Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA 02129;

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http://dx.doi.org/10.4049/jimmunol.1700409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716898PMC
December 2017

Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets.

N Engl J Med 2017 12;377(26):2565-2579

From the Department of Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Freiburg University, Freiburg, Germany (R.Z.); and the Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis (B.R.B.).

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http://dx.doi.org/10.1056/NEJMra1703472DOI Listing
December 2017

Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.

N Engl J Med 2017 11;377(22):2167-2179

From the Department of Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Center, Freiburg, Germany (R.Z.); and the Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis (B.R.B.).

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http://dx.doi.org/10.1056/NEJMra1609337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034180PMC
November 2017

Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT.

Blood Adv 2017 Oct 23;1(23):2083-2087. Epub 2017 Oct 23.

Division of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1182/bloodadvances.2017010926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728290PMC
October 2017