Bruce M Boman

Bruce M Boman

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Bruce M Boman

Bruce M Boman

Publications by authors named "Bruce M Boman"

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Gene expression signatures for HOXA4, HOXA9, and HOXD10 reveal alterations in transcriptional regulatory networks in colon cancer.

J Cell Physiol 2019 Aug 14;234(8):13042-13056. Epub 2018 Dec 14.

Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, Newark, Delaware.

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http://dx.doi.org/10.1002/jcp.27975DOI Listing
August 2019

Role of HOX Genes in Stem Cell Differentiation and Cancer.

Stem Cells Int 2018 22;2018:3569493. Epub 2018 Jul 22.

Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, Newark, DE, USA.

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http://dx.doi.org/10.1155/2018/3569493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081605PMC
July 2018

Multi-scale modeling of APC and [Formula: see text]-catenin regulation in the human colonic crypt.

J Math Biol 2018 Jun 4;76(7):1797-1830. Epub 2018 Jan 4.

Department of Biological Sciences, University of Delaware, Newark, DE, 19711, USA.

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http://dx.doi.org/10.1007/s00285-017-1204-8DOI Listing
June 2018

Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation.

J Cell Physiol 2018 Feb 11;233(2):727-735. Epub 2017 Jul 11.

Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, Newark, Delaware.

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http://dx.doi.org/10.1002/jcp.25981DOI Listing
February 2018

A kinetic model to study the regulation of β-catenin, APC, and Axin in the human colonic crypt.

J Math Biol 2017 11 7;75(5):1171-1202. Epub 2017 Mar 7.

Department of Biological Sciences, University of Delaware, Newark, DE, 19711, USA.

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http://dx.doi.org/10.1007/s00285-017-1112-yDOI Listing
November 2017

Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells.

BMC Cancer 2016 12 7;16(1):941. Epub 2016 Dec 7.

Department of Biological Sciences, University of Delaware, 118 Wolf Hall, Newark, DE, 19716, USA.

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http://dx.doi.org/10.1186/s12885-016-2969-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142402PMC
December 2016

Interdependence of DNA mismatch repair proteins MLH1 and MSH2 in apoptosis in human colorectal carcinoma cell lines.

Mol Cell Biochem 2016 Jan 4;412(1-2):297-305. Epub 2016 Jan 4.

Department of Biology, College of Arts, Letters and Sciences, University of Arkansas at Little Rock, 2801 S. University Avenue, Little Rock, AR, 72204, USA.

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http://link.springer.com/10.1007/s11010-015-2636-3
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http://dx.doi.org/10.1007/s11010-015-2636-3DOI Listing
January 2016

The Proportion of ALDEFLUOR-Positive Cancer Stem Cells Changes with Cell Culture Density Due to the Expression of Different ALDH Isoforms.

Cancer Stud Mol Med 2015 9;2(2):87-95. Epub 2015 Dec 9.

Department of Biological Sciences, University of Delaware, 118 Wolf Hall, Newark, DE 19716, USA; Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, 4701 Ogletown-Stanton Rd, Newark, DE 19713, USA.

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http://dx.doi.org/10.17140/CSMMOJ-2-113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340268PMC
December 2015

The miRNA23b-regulated signaling network as a key to cancer development--implications for translational research and therapeutics.

J Mol Med (Berl) 2014 Nov 11;92(11):1129-38. Epub 2014 Oct 11.

Department of Biological Sciences, University of Delaware, 118, Wolf Hall, Newark, DE, 19716, USA.

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http://dx.doi.org/10.1007/s00109-014-1208-4DOI Listing
November 2014

HOX genes and their role in the development of human cancers.

J Mol Med (Berl) 2014 Aug 5;92(8):811-23. Epub 2014 Jul 5.

Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, University of Delaware, 4701 Ogletown-Stanton Road, Newark, DE, 19713, USA.

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http://dx.doi.org/10.1007/s00109-014-1181-yDOI Listing
August 2014

An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative Abnormalities That Drive Colon Cancer Development.

Front Oncol 2013 Nov 7;3:244. Epub 2013 Nov 7.

Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, University of Delaware , Newark, DE , USA ; Kimmel Cancer Center, Thomas Jefferson University , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fonc.2013.00244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819610PMC
November 2013

Ureteroscopic management of upper tract urothelial carcinoma (UTUC) in patients with Lynch Syndrome (hereditary nonpolyposis colorectal cancer syndrome).

BJU Int 2013 Oct 1;112(6):813-9. Epub 2013 Mar 1.

Department of Urology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bju.12008DOI Listing
October 2013

Dysplastic lesions in inflammatory bowel disease show increased positivity for the stem cell marker aldehyde dehydrogenase.

Hum Pathol 2012 Feb 4;43(2):238-42. Epub 2011 Aug 4.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.humpath.2011.04.026DOI Listing
February 2012

Cancer stem cells: a step toward the cure.

J Clin Oncol 2008 Jun;26(17):2795-9

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http://ascopubs.org/doi/10.1200/JCO.2008.17.7436
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http://dx.doi.org/10.1200/JCO.2008.17.7436DOI Listing
June 2008

Human colon cancer stem cells: a new paradigm in gastrointestinal oncology.

J Clin Oncol 2008 Jun;26(17):2828-38

Helen Graham Cancer Center, Christiana Care Health System, 4701 Ogletown-Stanton Rd, Newark, DE 19713, USA.

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http://dx.doi.org/10.1200/JCO.2008.17.6941DOI Listing
June 2008

How dysregulated colonic crypt dynamics cause stem cell overpopulation and initiate colon cancer.

Cancer Res 2008 May;68(9):3304-13

Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-2061DOI Listing
May 2008

Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: a search for a uniform approach to a troubling disease.

Dis Colon Rectum 2005 Aug;48(8):1528-34

Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1007/s10350-005-0018-8DOI Listing
August 2005

Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population.

Am J Pathol 2004 Nov;165(5):1489-98

Division of Genetic and Preventive Medicine, Kimmel Cancer Center, 1100 Walnut St., Suite 400, Thomas Jefferson University, Philadelphia PA 19107, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618673PMC
http://dx.doi.org/10.1016/S0002-9440(10)63407-4DOI Listing
November 2004

The chemopreventive agent sulindac attenuates expression of the antiapoptotic protein survivin in colorectal carcinoma cells.

J Pharmacol Exp Ther 2004 Feb 10;308(2):434-7. Epub 2003 Nov 10.

Division of Genetic and Preventive Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.103.05937
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http://dx.doi.org/10.1124/jpet.103.059378DOI Listing
February 2004

Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells.

Cancer Res 2003 Apr;63(8):1748-51

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2279, USA.

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April 2003