Bruce L Miller

Bruce L Miller

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Bruce L Miller

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Relative preservation of facial expression recognition in posterior cortical atrophy.

Neurology 2019 Mar 13;92(10):e1064-e1071. Epub 2019 Feb 13.

From the Department of Neurology, Division of Behavioral Neurology and Neuropsychiatry (P.P., V.P.), University of Colorado, Denver; Memory and Aging Center (P.P., K.G., S.M.S., B.L.M., C.M., K.P.R.), University of California, San Francisco; and Stanford Neuroscience Health Center (C.F.), Stanford University School of Medicine, Palo Alto, CA.

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http://dx.doi.org/10.1212/WNL.0000000000007075DOI Listing
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gena Roschupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Mar 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
March 2019

Longitudinal tau accumulation and atrophy in aging and alzheimer disease.

Ann Neurol 2019 Feb 17;85(2):229-240. Epub 2019 Jan 17.

Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA.

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http://dx.doi.org/10.1002/ana.25406DOI Listing
February 2019

The Rise of Pseudomedicine for Dementia and Brain Health.

JAMA 2019 02;321(6):543-544

Memory and Aging Center, Department of Neurology, University of California, San Francisco.

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http://dx.doi.org/10.1001/jama.2018.21560DOI Listing
February 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Feb 9. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
February 2019

Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity.

Neuroimage Clin 2019 Feb 23;22:101729. Epub 2019 Feb 23.

Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101729DOI Listing
February 2019

Genetic screen in a large series of patients with primary progressive aphasia.

Alzheimers Dement 2019 Jan 24. Epub 2019 Jan 24.

Department of Psychiatry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.10.009DOI Listing
January 2019

Evaluating Patient Brain and Behavior Pathways to Caregiver Health in Neurodegenerative Diseases.

Dement Geriatr Cogn Disord 2019 Jan 10;47(1-2):42-54. Epub 2019 Jan 10.

Department of Psychology, University of California, Berkeley, Berkeley, California,

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https://www.karger.com/Article/FullText/495345
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http://dx.doi.org/10.1159/000495345DOI Listing
January 2019

Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers.

J Alzheimers Dis 2019 ;67(3):911-921

University of California San Francisco, Memory and Aging Center, Weill Institute for the Neurosciences, San Francisco, CA, USA.

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http://dx.doi.org/10.3233/JAD-181145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398835PMC
January 2019

Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series.

J Neurol 2018 Dec 15;265(12):2960-2971. Epub 2018 Oct 15.

Department of Neurology, Memory and Aging Center, University of California San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA.

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http://link.springer.com/10.1007/s00415-018-9086-2
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http://dx.doi.org/10.1007/s00415-018-9086-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245666PMC
December 2018

Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar?

Neuroimage Clin 2019 3;21:101628. Epub 2018 Dec 3.

Memory and Aging Center, University of California, 675 Nelson Rising Lane, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.101628DOI Listing
December 2018

Molecular imaging in dementia: Past, present, and future.

Alzheimers Dement 2018 Nov 18;14(11):1522-1552. Epub 2018 Jul 18.

Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2018.06.2855DOI Listing
November 2018

Cognition and Incarceration: Cognitive Impairment and Its Associated Outcomes in Older Adults in Jail.

J Am Geriatr Soc 2018 Nov 19;66(11):2065-2071. Epub 2018 Sep 19.

Division of Geriatrics Department of Medicine, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1111/jgs.15521DOI Listing
November 2018

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Ann Neurol 2018 Nov;84(5):729-740

Alzheimer center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/ana.25333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354051PMC
November 2018

"Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders.

Front Aging Neurosci 2018 9;10:343. Epub 2018 Nov 9.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fnagi.2018.00343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244607PMC
November 2018

The Care Ecosystem: Promoting self-efficacy among dementia family caregivers.

Dementia (London) 2018 Nov 29:1471301218814121. Epub 2018 Nov 29.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1471301218814121DOI Listing
November 2018

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.

Brain 2018 Oct;141(10):2895-2907

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/brain/awy238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158742PMC
October 2018

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.

Neurol Genet 2018 Oct 1;4(5):e266. Epub 2018 Oct 1.

Department of Neurology (L.W.B., N.Z.R.S., E.G.G., Z.A.M., B.L.M., W.W.S., J.S.Y.), Memory and Aging Center, University of California, San Francisco; Department of Psychiatry (C.M.K., N.W., A.O.-K.), Washington University, St. Louis, MO; School of Pharmacy (C.M., P.L.), University of Reading, Reading, UK; Laboratory of Neurogenetics (P.M.), Texas Tech University Health Science Center, Lubbock; Department of Molecular Neuroscience (C.M., J.H., P.L., R.F.), UCL Institute of Neurology, London, UK; Department of Radiology and Biomedical Imaging, Neuroradiology Section (C.P.H., R.S.D.), University of California, San Francisco; and Department of Neurology (S.E.B.), University of California, San Francisco.

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http://ng.neurology.org/lookup/doi/10.1212/NXG.0000000000000
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http://dx.doi.org/10.1212/NXG.0000000000000266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167176PMC
October 2018

Frontotemporal dementia.

Handb Clin Neurol 2018 ;148:409-430

Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-64076-5.00027-2DOI Listing
August 2018

A mosquito bites and a butterfly flies: A specific response type of frontal patients in a similarity task.

Neuropsychologia 2018 08 26;117:371-378. Epub 2018 Jun 26.

Institut du Cerveau et de la Moelle épinière (ICM), UPMC UMRS 1127, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology department, Memory and Aging center, Pitié-Salpêtrière Hospital, AP-HP, Paris, France; Neurology department, Behavioral Neuro-psychiatry Unit, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.

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http://dx.doi.org/10.1016/j.neuropsychologia.2018.06.022DOI Listing
August 2018

Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy.

Neuroimage Clin 2017 12;16:564-574. Epub 2017 Sep 12.

Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605489PMC
June 2018

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.

Neuroimage Clin 2017 14;16:595-603. Epub 2017 Sep 14.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, United States.

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http://dx.doi.org/10.1016/j.nicl.2017.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614750PMC
June 2018

Individual differences in socioemotional sensitivity are an index of salience network function.

Cortex 2018 Jun 27;103:211-223. Epub 2018 Feb 27.

Memory and Aging Center, University of California, San Francisco, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2018.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143366PMC
June 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181PMC
June 2018

Enhanced Positive Emotional Reactivity Undermines Empathy in Behavioral Variant Frontotemporal Dementia.

Front Neurol 2018 4;9:402. Epub 2018 Jun 4.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fneur.2018.00402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994409PMC
June 2018

Neuroanatomy of Shared Conversational Laughter in Neurodegenerative Disease.

Front Neurol 2018 15;9:464. Epub 2018 Jun 15.

Berkeley Psychophysiology Center, University of California, Berkeley, Berkeley, CA, United States.

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http://dx.doi.org/10.3389/fneur.2018.00464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013725PMC
June 2018

Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment.

Ann Clin Transl Neurol 2018 May 2;5(5):616-629. Epub 2018 Apr 2.

Department of Psychiatry Semel Institute for Neuroscience and Human Behavior University of California Los Angeles Los Angeles California.

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http://dx.doi.org/10.1002/acn3.560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945969PMC
May 2018

Empathic Accuracy Deficits in Patients with Neurodegenerative Disease: Association with Caregiver Depression.

Am J Geriatr Psychiatry 2018 Apr 27;26(4):484-493. Epub 2017 Dec 27.

Department of Psychology, University of California, Berkeley, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2017.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860967PMC
April 2018

Artistic Renaissance in Frontotemporal Dementia.

JAMA 2018 04;319(13):1304-1306

Memory and Aging Center, Department of Neurology, University of California, San Francisco.

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http://dx.doi.org/10.1001/jama.2017.19501DOI Listing
April 2018

Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration.

Neurology 2018 Mar 16;90(12):e1047-e1056. Epub 2018 Feb 16.

From the Memory and Aging Center, Department of Neurology (S.W.S., D.C.P., A.H., M.S., I.S., J.N.S.V., S.E.G., G.R., K.D.R., A.L.B., J.H.K., H.J.R., M.L.G.-T., L.T.G., B.L.M., W.W.S.), and Department of Pathology (L.T.G., E.J.H., S.J.D., W.W.S.), University of California, San Francisco; Department of Neurology (S.W.S.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Geriatrics (M.-P.T.), Centre Hospitalier de l'Université de Montréal, University of Montreal, Canada; and Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research and Institute on Aging (J.Q.T.), University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1212/WNL.0000000000005163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874448PMC
March 2018

Multiproteinopathy, neurodegeneration and old age: a case study.

Neurocase 2018 Feb 6;24(1):1-6. Epub 2018 Jan 6.

a Memory and Aging Center, Department of Neurology , University of California San Francisco , San Francisco, USA.

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http://dx.doi.org/10.1080/13554794.2017.1420199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877460PMC
February 2018

Serum BDNF Is Positively Associated With Negative Symptoms in Older Adults With Schizophrenia.

Biol Res Nurs 2018 01 19;20(1):63-69. Epub 2017 Oct 19.

2 Department of Physiological Nursing, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1099800417735634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942501PMC
January 2018

CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP.

Neurology 2018 Jan 27;90(4):e273-e281. Epub 2017 Dec 27.

From the Memory and Aging Center, Department of Neurology (J.C.R., R.M.T., G.D.R., B.L.M., A.L.B.), and Department of Epidemiology and Biostatistics, Division of Biostatistics (I.V.L.), University of California, San Francisco; and Department of Neurology (J.B.), Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000004859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798651PMC
January 2018

Associations between [F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample.

Neurology 2018 Jan 27;90(4):e282-e290. Epub 2017 Dec 27.

From the Memory and Aging Center (R.L.J., A.B., N.A., V.B., A.L.B., J.C., A.K., A.M., Z.A.M., J.P., H.J.R., R.T., A.V., B.L.M., G.D.R.), University of California San Francisco; Knight Alzheimer's Disease Research Center (A.M.F., G.J.), Department of Neurology (A.M.F., G.J.), and The Hope Center for Neurological Disorders (A.M.F., G.J.), Washington University in St. Louis, MO; Molecular Biophysics and Integrated Bioimaging Division (S.L.B., J.P.O., W.J.J.), Lawrence Berkeley National Laboratory, Berkeley, CA; and Helen Wills Neuroscience Institute (A.M., W.J.J., G.D.R.), University of California Berkeley.

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http://dx.doi.org/10.1212/WNL.0000000000004860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798657PMC
January 2018

Prominent Non-Memory Deficits in Alzheimer's Disease Are Associated with Faster Disease Progression.

J Alzheimers Dis 2018 ;65(3):1029-1039

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.3233/JAD-171088DOI Listing
January 2018

Cognitive subtypes of probable Alzheimer's disease robustly identified in four cohorts.

Alzheimers Dement 2017 Nov 17;13(11):1226-1236. Epub 2017 Apr 17.

Department of Neurology, Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2017.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857387PMC
November 2017

Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy.

Sleep 2017 11;40(11)

Department of Mental Health, Stress and Health Research Program, San Francisco VA Medical Center, 4150 Clement Street 116P Building 8, San Francisco, CA 94121.

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http://dx.doi.org/10.1093/sleep/zsx154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251530PMC
November 2017

Mistakes, Too Few to Mention? Impaired Self-conscious Emotional Processing of Errors in the Behavioral Variant of Frontotemporal Dementia.

Front Behav Neurosci 2017 17;11:189. Epub 2017 Oct 17.

Department of Neurology, UCSF Memory and Aging Center San Francisco, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fnbeh.2017.00189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651000PMC
October 2017

Focal cerebral β-amyloid angiopathy: A distinct clinicopathologic presentation.

Neurol Clin Pract 2017 Oct;7(5):444-448

Memory and Aging Center (EK, GN, GT, BLM, GDR, LTG) and Multiple Sclerosis and Neuroinflammation Center (SJP, JMG), Department of Neurology, and Department of Pathology and Laboratory Medicine (SA), University of California San Francisco; Neurological Institute of Athens (EK), Greece; and Department of Pathology (LTG), University of São Paulo Medical School, Brazil. S.A. is currently affiliated with Boston Children's Hospital, MA.

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http://dx.doi.org/10.1212/CPJ.0000000000000354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874474PMC
October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

A clinicopathological approach to the diagnosis of dementia.

Nat Rev Neurol 2017 Aug 14;13(8):457-476. Epub 2017 Jul 14.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nrneurol.2017.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771416PMC
August 2017

Poor caregiver mental health predicts mortality of patients with neurodegenerative disease.

Proc Natl Acad Sci U S A 2017 07 27;114(28):7319-7324. Epub 2017 Jun 27.

Department of Psychology, University of California, Berkeley, CA 94720;

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http://dx.doi.org/10.1073/pnas.1701597114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514722PMC
July 2017

Increased subjective experience of non-target emotions in patients with frontotemporal dementia and Alzheimer's disease.

Curr Opin Behav Sci 2017 Jun 7;15:77-84. Epub 2017 Jun 7.

Institute of Personality and Social Research, University of California, Berkeley, CA 94720-5050, United States.

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http://dx.doi.org/10.1016/j.cobeha.2017.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810592PMC
June 2017

Frontotemporal Dementia.

Neurol Clin 2017 May;35(2):339-374

Department of Neurology, UCSF Memory and Aging Center, San Francisco, CA, USA; UCSF School of Medicine, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.ncl.2017.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472209PMC
May 2017

Poly(GP) proteins are a useful pharmacodynamic marker for -associated amyotrophic lateral sclerosis.

Sci Transl Med 2017 03;9(383)

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1126/scitranslmed.aai7866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576451PMC
March 2017