Bruce L Miller

Bruce L Miller

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Bruce L Miller

Bruce L Miller

Publications by authors named "Bruce L Miller"

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100Publications

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Network architecture underlying basal autonomic outflow: Evidence from frontotemporal dementia.

J Neurosci 2018 Sep 4. Epub 2018 Sep 4.

Department of Neurology; University of California, San Francisco; Sandler Neurosciences Center; 675 Nelson Rising Lane, Suite 190; San Francisco, CA 94158, USA.

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September 2018

Frontotemporal dementia.

Handb Clin Neurol 2018 ;148:409-430

Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, United States. Electronic address:

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August 2018

A mosquito bites and a butterfly flies: A specific response type of frontal patients in a similarity task.

Neuropsychologia 2018 Aug 26;117:371-378. Epub 2018 Jun 26.

Institut du Cerveau et de la Moelle épinière (ICM), UPMC UMRS 1127, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology department, Memory and Aging center, Pitié-Salpêtrière Hospital, AP-HP, Paris, France; Neurology department, Behavioral Neuro-psychiatry Unit, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.

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August 2018

Deconstructing empathy: Neuroanatomical dissociations between affect sharing and prosocial motivation using a patient lesion model.

Neuropsychologia 2018 Jul 14;116(Pt A):126-135. Epub 2017 Feb 14.

Memory and Aging Center, University of California, San Francisco, USA. Electronic address:

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July 2018

Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer's Disease Pathology and Shows Differential Expression in Transgenic Mice.

Front Neurosci 2018 16;12:476. Epub 2018 Jul 16.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.

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July 2018

Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy.

Neuroimage Clin 2017 12;16:564-574. Epub 2017 Sep 12.

Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.

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June 2018

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.

Neuroimage Clin 2017 14;16:595-603. Epub 2017 Sep 14.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, United States.

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June 2018

Individual differences in socioemotional sensitivity are an index of salience network function.

Cortex 2018 Jun 27;103:211-223. Epub 2018 Feb 27.

Memory and Aging Center, University of California, San Francisco, United States. Electronic address:

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June 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 Jun 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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June 2018

Enhanced Positive Emotional Reactivity Undermines Empathy in Behavioral Variant Frontotemporal Dementia.

Front Neurol 2018 4;9:402. Epub 2018 Jun 4.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.

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June 2018

Neuroanatomy of Shared Conversational Laughter in Neurodegenerative Disease.

Front Neurol 2018 15;9:464. Epub 2018 Jun 15.

Berkeley Psychophysiology Center, University of California, Berkeley, Berkeley, CA, United States.

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June 2018

Emotion detection deficits and changes in personality traits linked to loss of white matter integrity in primary progressive aphasia.

Neuroimage Clin 2017 26;16:447-454. Epub 2017 Aug 26.

Division of Neurology, Krembil Neuroscience Centre, Toronto Western Hospital, University Health Network, 399 Bathurst St., Toronto, ON M5T2S8, Canada.

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May 2018

Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment.

Ann Clin Transl Neurol 2018 May 2;5(5):616-629. Epub 2018 Apr 2.

Department of Psychiatry Semel Institute for Neuroscience and Human Behavior University of California Los Angeles Los Angeles California.

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May 2018

Empathic Accuracy Deficits in Patients with Neurodegenerative Disease: Association with Caregiver Depression.

Am J Geriatr Psychiatry 2018 Apr 27;26(4):484-493. Epub 2017 Dec 27.

Department of Psychology, University of California, Berkeley, CA. Electronic address:

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April 2018

Artistic Renaissance in Frontotemporal Dementia.

JAMA 2018 04;319(13):1304-1306

Memory and Aging Center, Department of Neurology, University of California, San Francisco.

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April 2018

Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration.

Neurology 2018 Mar 16;90(12):e1047-e1056. Epub 2018 Feb 16.

From the Memory and Aging Center, Department of Neurology (S.W.S., D.C.P., A.H., M.S., I.S., J.N.S.V., S.E.G., G.R., K.D.R., A.L.B., J.H.K., H.J.R., M.L.G.-T., L.T.G., B.L.M., W.W.S.), and Department of Pathology (L.T.G., E.J.H., S.J.D., W.W.S.), University of California, San Francisco; Department of Neurology (S.W.S.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Geriatrics (M.-P.T.), Centre Hospitalier de l'Université de Montréal, University of Montreal, Canada; and Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research and Institute on Aging (J.Q.T.), University of Pennsylvania, Philadelphia.

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March 2018

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay.

Proc Natl Acad Sci U S A 2018 03 6;115(12):E2849-E2858. Epub 2018 Mar 6.

Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115;

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March 2018

Multiproteinopathy, neurodegeneration and old age: a case study.

Neurocase 2018 Feb 6;24(1):1-6. Epub 2018 Jan 6.

a Memory and Aging Center, Department of Neurology , University of California San Francisco , San Francisco, USA.

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February 2018

Serum BDNF Is Positively Associated With Negative Symptoms in Older Adults With Schizophrenia.

Biol Res Nurs 2018 Jan 19;20(1):63-69. Epub 2017 Oct 19.

2 Department of Physiological Nursing, University of California, San Francisco, CA, USA.

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January 2018

CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP.

Neurology 2018 Jan 27;90(4):e273-e281. Epub 2017 Dec 27.

From the Memory and Aging Center, Department of Neurology (J.C.R., R.M.T., G.D.R., B.L.M., A.L.B.), and Department of Epidemiology and Biostatistics, Division of Biostatistics (I.V.L.), University of California, San Francisco; and Department of Neurology (J.B.), Johns Hopkins University School of Medicine, Baltimore, MD.

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January 2018

Associations between [F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample.

Neurology 2018 Jan 27;90(4):e282-e290. Epub 2017 Dec 27.

From the Memory and Aging Center (R.L.J., A.B., N.A., V.B., A.L.B., J.C., A.K., A.M., Z.A.M., J.P., H.J.R., R.T., A.V., B.L.M., G.D.R.), University of California San Francisco; Knight Alzheimer's Disease Research Center (A.M.F., G.J.), Department of Neurology (A.M.F., G.J.), and The Hope Center for Neurological Disorders (A.M.F., G.J.), Washington University in St. Louis, MO; Molecular Biophysics and Integrated Bioimaging Division (S.L.B., J.P.O., W.J.J.), Lawrence Berkeley National Laboratory, Berkeley, CA; and Helen Wills Neuroscience Institute (A.M., W.J.J., G.D.R.), University of California Berkeley.

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January 2018

The Brain Health Assessment for Detecting and Diagnosing Neurocognitive Disorders.

J Am Geriatr Soc 2018 Jan;66(1):150-156

Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California.

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January 2018

Prominent Non-Memory Deficits in Alzheimer's Disease Are Associated with Faster Disease Progression.

J Alzheimers Dis 2018 ;65(3):1029-1039

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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January 2018

Regional correlations between [C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort.

Neuroimage Clin 2017 11;13:130-137. Epub 2016 Nov 11.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, USA; Lawrence Berkeley National Laboratory, USA.

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November 2017

Cognitive subtypes of probable Alzheimer's disease robustly identified in four cohorts.

Alzheimers Dement 2017 Nov 17;13(11):1226-1236. Epub 2017 Apr 17.

Department of Neurology, Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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November 2017

Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy.

Sleep 2017 11;40(11)

Department of Mental Health, Stress and Health Research Program, San Francisco VA Medical Center, 4150 Clement Street 116P Building 8, San Francisco, CA 94121.

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November 2017

Mistakes, Too Few to Mention? Impaired Self-conscious Emotional Processing of Errors in the Behavioral Variant of Frontotemporal Dementia.

Front Behav Neurosci 2017 17;11:189. Epub 2017 Oct 17.

Department of Neurology, UCSF Memory and Aging Center San Francisco, University of California, San Francisco, San Francisco, CA, United States.

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October 2017

Focal cerebral β-amyloid angiopathy: A distinct clinicopathologic presentation.

Neurol Clin Pract 2017 Oct;7(5):444-448

Memory and Aging Center (EK, GN, GT, BLM, GDR, LTG) and Multiple Sclerosis and Neuroinflammation Center (SJP, JMG), Department of Neurology, and Department of Pathology and Laboratory Medicine (SA), University of California San Francisco; Neurological Institute of Athens (EK), Greece; and Department of Pathology (LTG), University of São Paulo Medical School, Brazil. S.A. is currently affiliated with Boston Children's Hospital, MA.

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October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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September 2017

A clinicopathological approach to the diagnosis of dementia.

Nat Rev Neurol 2017 Aug 14;13(8):457-476. Epub 2017 Jul 14.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, California 94158, USA.

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August 2017

Poor caregiver mental health predicts mortality of patients with neurodegenerative disease.

Proc Natl Acad Sci U S A 2017 07 27;114(28):7319-7324. Epub 2017 Jun 27.

Department of Psychology, University of California, Berkeley, CA 94720;

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July 2017

Increased subjective experience of non-target emotions in patients with frontotemporal dementia and Alzheimer's disease.

Curr Opin Behav Sci 2017 Jun 7;15:77-84. Epub 2017 Jun 7.

Institute of Personality and Social Research, University of California, Berkeley, CA 94720-5050, United States.

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June 2017

Multicellular hypothesis for the pathogenesis of Alzheimer's disease.

FASEB J 2017 05 18;31(5):1792-1795. Epub 2017 Jan 18.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, California, USA.

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May 2017

Observing conversational laughter in frontotemporal dementia.

J Neurol Neurosurg Psychiatry 2017 05 24;88(5):418-424. Epub 2017 Feb 24.

Berkeley Psychophysiology Laboratory, University of California, Berkeley, California, USA.

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May 2017

Frontotemporal Dementia.

Neurol Clin 2017 May;35(2):339-374

Department of Neurology, UCSF Memory and Aging Center, San Francisco, CA, USA; UCSF School of Medicine, San Francisco, CA, USA.

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May 2017

Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.

Brain Imaging Behav 2017 04;11(2):391-400

Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA.

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April 2017

Abnormal vocal behavior predicts executive and memory deficits in Alzheimer's disease.

Neurobiol Aging 2017 04 3;52:71-80. Epub 2017 Jan 3.

Speech Neuroscience Laboratory, Department of Otolaryngology - Head and Neck Surgery, University of California San Francisco, San Francisco, CA, USA; Biomagnetic Imaging Laboratory, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA. Electronic address:

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April 2017

Epileptic activity in Alzheimer's disease: causes and clinical relevance.

Lancet Neurol 2017 04;16(4):311-322

Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA.

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April 2017

Genome-wide association study identifies locus influencing human plasma tau levels.

Neurology 2017 Feb 18;88(7):669-676. Epub 2017 Jan 18.

From the Department of Neurology (J.C., K.W., G.C.), David Geffen School of Medicine, and Memory and Aging Center (J.S.Y., J.H.K., H.R., B.L.M., A.L.B.), Department of Neurology, University of California, Los Angeles; Department of Neurology (J.-T.Y., H.-F.W.), Qingdao Municipal Hospital, Nanjing Medical University, China; Clinical Neurochemistry Laboratory (H.Z., K.B.), Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg Mölndal, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, London, UK; and Center for Imaging of Neurodegenerative Diseases (M.W.W.), VAMC San Francisco, CA.

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February 2017

Frontotemporal dementia with the V337M mutation: Tau-PET and pathology correlations.

Neurology 2017 Feb 27;88(8):758-766. Epub 2017 Jan 27.

From the Memory and Aging Center (S.S., D.R.S., W.W.S., R.O., A.L., H.J.R., A.L.B., D.C.P., B.L.M., G.D.R.), Department of Neurology, and Department of Pathology (W.W.S), University of California, San Francisco; Department of Neurology (B.F.B., J.E.P.), Mayo Clinic, Rochester, MN; Helen Wills Neuroscience Institute (R.O., W.J.J., G.D.R.), University of California Berkeley; Alzheimercenter (R.O.), VU University Medical Center, Amsterdam, the Netherlands; Lawrence Berkeley National Laboratory (J.P.O., W.J.J., M.E.M., G.D.R.), Berkeley, CA; and Department of Pathology (D.W.D.), Mayo Clinic, Jacksonville, FL.

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February 2017

Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease.

Neurocase 2017 Feb;23(1):65-69

a Memory and Aging Center, Department of Neurology , University of California, San Francisco , San Francisco , CA , USA.

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February 2017

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease.

FASEB J 2016 12 6;30(12):4141-4148. Epub 2016 Sep 6.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, California, USA.

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December 2016

Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.

Neurol Neuroimmunol Neuroinflamm 2016 Dec 28;3(6):e301. Epub 2016 Oct 28.

Memory and Aging Center (Z.A.M., V.E.S., A.K., J.S.Y., L.T.G., A.L.B., H.J.R., K.P.R., M.L.G.-T., W.W.S., B.L.M.) and Department of Pathology (L.T.G., W.W.S.), University of California, San Francisco; Departments of Neurology (G.B.C., N.R.G.-R.) and Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL; and Department of Neurology (G.C., D.H.G.), David Geffen School of Medicine, University of California, Los Angeles, CA.

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December 2016

Progression of brain atrophy in PSP and CBS over 6 months and 1 year.

Neurology 2016 Nov 14;87(19):2016-2025. Epub 2016 Oct 14.

Department of Neurology (S.D., R.J.B., H.W.H., P.L., S.A., P.B., G.A.M., J.E., D.W., L.V., G.D.R., J.H.K., B.L.M., H.J.R., A.L.B.), University of California, San Francisco, Memory and Aging Center; Department of Communication Sciences & Disorders (R.J.B.), Saffran Center for Cognitive Neuroscience, Temple University, Philadelphia, PA; Tanz Centre for Research in Neurodegenerative Disease (M.C.T.), University of Toronto, Canada; Department of Neurosciences (I.L.), University of California, San Diego, La Jolla, CA; Gerontology Research Unit (S.M.M., B.C.D.), Massachusetts General Hospital, Harvard Medical School, Charlestown, MA; Departments of Epidemiology & Biostatistics (J.K.) and Radiology (N.S.), University of California, San Francisco; Department of Psychiatry and Behavioral Sciences (D.W.), Stanford University, CA; Department of Radiology (C.R.J.), Mayo Clinic, Rochester, MN.

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November 2016

Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease.

FASEB J 2016 11 10;30(11):3853-3859. Epub 2016 Aug 10.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.

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November 2016

Diagnostic utility of ASL-MRI and FDG-PET in the behavioral variant of FTD and AD.

Ann Clin Transl Neurol 2016 10 30;3(10):740-751. Epub 2016 Aug 30.

Memory and Aging Center Department of Neurology University of California San Francisco California.

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October 2016

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.

Neuron 2016 Oct 6;92(2):383-391. Epub 2016 Oct 6.

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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October 2016

Clinical and imaging characteristics of late onset mitochondrial membrane protein-associated neurodegeneration (MPAN).

Neurocase 2016 10 1;22(5):476-483. Epub 2016 Nov 1.

a Department of Neurology , University Hospitals Case Medical Center , Beachwood , OH , USA.

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October 2016

Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.

Stem Cell Reports 2016 09 1;7(3):325-340. Epub 2016 Sep 1.

Department of Neurology, Chemical Neurobiology Laboratory, Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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September 2016

MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations.

Stem Cell Reports 2016 09 1;7(3):316-324. Epub 2016 Sep 1.

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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September 2016

Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.

Ann Clin Transl Neurol 2016 Sep 26;3(9):668-77. Epub 2016 Aug 26.

Memory and Aging Center Department of Neurology University of California, San Francisco San Francisco California.

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September 2016