Bruce Kirkham

Bruce Kirkham

UNVERIFIED PROFILE

Are you Bruce Kirkham?   Register this Author

Register author
Bruce Kirkham

Bruce Kirkham

Publications by authors named "Bruce Kirkham"

Are you Bruce Kirkham?   Register this Author

53Publications

1217Reads

7Profile Views

The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies.

Ann Rheum Dis 2019 Sep 5;78(9):1167-1178. Epub 2019 Jul 5.

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2019-215356DOI Listing
September 2019

Best-practice Indicators in Psoriatic Disease Care.

J Rheumatol Suppl 2019 Jun;95:38-45

From the Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds; Bradford Hospitals National Health Service (NHS) Foundation Trust, Bradford; Global Strategy Group, Healthcare and Life Sciences, KPMG LLP, London; Guy's and St. Thomas' NHS Foundation Trust, Kings College London, London; University of Oxford, Oxford, UK; University of Toronto, Toronto, Ontario; Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Buenos Aires; University Institute Hospital Italiano de Buenos Aires, Buenos Aires; Argentina; Hospital de la Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Division of Dermatology and Venereology, Geneva University Hospitals, Geneva; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland; Research Institute and Comprehensive Center for Inflammation Medicine, University of Luebeck, Luebeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.190120DOI Listing
June 2019

IL-17 in the immunopathogenesis of spondyloarthritis.

Nat Rev Rheumatol 2018 08;14(8):453-466

Department of Rheumatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41584-018-0044-2DOI Listing
August 2018

A new era for collaboration?

Rheumatology (Oxford) 2018 05;57(5):775-776

Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kex083DOI Listing
May 2018

Enthesitis: from pathophysiology to treatment.

Nat Rev Rheumatol 2017 Nov;13(12):731-741

Section of Musculoskeletal Diseases, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and Chapel Allerton Hospital, Chapeltown Road, Leeds, West Yorkshire LS7 4SA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrrheum.2017.188DOI Listing
November 2017

Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting.

J Rheumatol 2017 05;44(5):679-683

From Clinical Investigation, The Rockefeller University, New York; Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; Guy's and St. Thomas' UK National Health Service (NHS) Foundation Trust; King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.170143DOI Listing
May 2017

Rheumatoid arthritis patients with fibromyalgic clinical features have significantly less synovitis as defined by power Doppler ultrasound.

BMC Musculoskelet Disord 2016 Sep 23;17(1):404. Epub 2016 Sep 23.

Department of Rheumatology, Guys and St Thomas' NHS Trust, Great Maze Pond, London, SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12891-016-1258-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034619PMC
September 2016

TNF-α blockade induces IL-10 expression in human CD4+ T cells.

Nat Commun 2014 ;5:3199

Centre for Molecular & Cellular Biology of Inflammation (CMCBI), Division of Immunology, Infection and Inflammatory Disease, King's College London, SE1 1UL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms4199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918582PMC
October 2015

Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis.

N Engl J Med 2015 Oct;373(14):1329-39

From the Swedish Medical Center and the University of Washington - both in Seattle (P.J.M.); University of Glasgow, Glasgow (I.B.M.), and Guy's and St. Thomas' NHS Foundation Trust, London (B.K.) - both in the United Kingdom; University of California, San Diego, School of Medicine, San Diego (A.K.); Memorial University, St. John's, NL, Canada (P.R.); Leiden University Medical Center, Leiden (D.H.), and University of Amsterdam and Atrium Medical Center, Amsterdam (R.L.) - all in the Netherlands; University of Queensland, Brisbane, Australia (P.N.); Novartis Pharmaceuticals, East Hanover, NJ (L.P., J.Y.); and Novartis Pharma, Basel, Switzerland (H.B.R., S.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1412679DOI Listing
October 2015

Rheumatoid Arthritis - Anti-TNF.

Int Immunopharmacol 2015 Aug 8;27(2):180-4. Epub 2015 May 8.

Rheumatology Department, Guy's & St Thomas' NHS Foundation Trust, London SE1 9RT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2015.04.051DOI Listing
August 2015

Interleukin-17A: a unique pathway in immune-mediated diseases: psoriasis, psoriatic arthritis and rheumatoid arthritis.

Immunology 2014 Feb;141(2):133-42

Department of Rheumatology, Guy's & St Thomas' NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imm.12142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904234PMC
February 2014

Disease assessment in psoriatic spectrum: a modular approach for use in routine clinical practice.

Ann Rheum Dis 2014 Jan 30;73(1):318-9. Epub 2013 Aug 30.

Department of Rheumatology, Guy's & St Thomas' NHS Foundation Trust, , London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2013-203798DOI Listing
January 2014

Effect of golimumab on carotid atherosclerotic disease measures and cardiovascular events in inflammatory arthritides.

J Clin Rheumatol 2014 Jan;20(1):1-10

From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester, MN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RHU.0000000000000053DOI Listing
January 2014

Paradoxical association of C-reactive protein with endothelial function in rheumatoid arthritis.

PLoS One 2010 Apr 27;5(4):e10242. Epub 2010 Apr 27.

King's College London, British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, UK.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010242PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860503PMC
April 2010

Functional and work outcomes improve in patients with rheumatoid arthritis who receive targeted, comprehensive occupational therapy.

Arthritis Rheum 2009 Nov;61(11):1522-30

Guy's & St. Thomas' National Health Service Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.24563DOI Listing
November 2009

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses.

Proc Natl Acad Sci U S A 2009 Apr 26;106(15):6232-7. Epub 2009 Mar 26.

Department of Immunobiology, King's College London School of Medicine at Guy's, King's College and St. Thomas' Hospitals, London SE1 1UL, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0808144106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669354PMC
April 2009

An examination of work instability, functional impairment, and disease activity in employed patients with rheumatoid arthritis.

J Rheumatol 2009 Feb 22;36(2):225-30. Epub 2009 Jan 22.

Guy's and St. Thomas' NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.071001DOI Listing
February 2009

Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium.

PLoS Med 2009 Jan;6(1):e1

William Harvey Research Institute, Barts and the London School of Medicine, Charterhouse Square, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pmed.0060001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621263PMC
January 2009

The synovial membrane as a prognostic tool in rheumatoid arthritis.

Autoimmun Rev 2007 Mar 8;6(4):248-52. Epub 2006 Sep 8.

Academic Department of Rheumatology, Kings College London School of Medicine, 5th Floor Thomas Guy House, Guy's Hospital, London SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.autrev.2006.08.013DOI Listing
March 2007

Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: standardization and consistency across centers.

J Rheumatol 2007 Mar;34(3):620-2

Department of Rheumatology, St. Vincent's University Hospital, and The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

View Article

Download full-text PDF

Source
March 2007

Cardiovascular issues of COX-2 inhibitors and NSAIDs.

Aust Fam Physician 2005 Nov;34(11):945-8

Department of Rheumatology, St Vincent's Hospital, Melbourne, Victoria.

View Article

Download full-text PDF

Source
November 2005

Accuracy and reliability of arthroscopic estimates of cartilage lesion size in a plastic knee simulation model.

Arthroscopy 2003 Mar;19(3):282-9

Deptartments of Rheumatology, St. George Hospital Campus, University of New South Wales, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S074980630237666
Publisher Site
http://dx.doi.org/10.1053/jars.2003.50039DOI Listing
March 2003