Bruce Futcher

Bruce Futcher

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Bruce Futcher

Bruce Futcher

Publications by authors named "Bruce Futcher"

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Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2.

Virology 2019 Nov 5;537:237-245. Epub 2019 Sep 5.

Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00426822193026
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http://dx.doi.org/10.1016/j.virol.2019.09.003DOI Listing
November 2019

Re-annotation of 12,495 prokaryotic 16S rRNA 3' ends and analysis of Shine-Dalgarno and anti-Shine-Dalgarno sequences.

PLoS One 2018 23;13(8):e0202767. Epub 2018 Aug 23.

Dept. of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202767PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107228PMC
February 2019

Prokaryotic coding regions have little if any specific depletion of Shine-Dalgarno motifs.

PLoS One 2018 23;13(8):e0202768. Epub 2018 Aug 23.

Dept. of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York City, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107199PMC
February 2019

Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes.

PLoS One 2018 7;13(9):e0198303. Epub 2018 Sep 7.

Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198303PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128446PMC
February 2019

and mRNAs are novel RNA targets of the Mei2 RNA-binding protein during early meiosis in .

Open Biol 2018 09 26;8(9). Epub 2018 Sep 26.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11790, USA.

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http://dx.doi.org/10.1098/rsob.180110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170507PMC
September 2018

Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs.

RNA 2016 09 11;22(9):1311-9. Epub 2016 Jul 11.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York 11794-5222, USA.

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http://rnajournal.cshlp.org/lookup/doi/10.1261/rna.051490.11
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http://dx.doi.org/10.1261/rna.051490.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986887PMC
September 2016

Cyclin-Dependent Kinase Co-Ordinates Carbohydrate Metabolism and Cell Cycle in S. cerevisiae.

Mol Cell 2016 05;62(4):546-57

Department of Molecular Genetics & Microbiology, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765163010
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http://dx.doi.org/10.1016/j.molcel.2016.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905568PMC
May 2016

A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression.

Nucleic Acids Res 2015 Aug 23;43(14):6874-88. Epub 2015 Apr 23.

Department of Molecular Genetics & Microbiology, Stony Brook University, Stony Brook, NY 11794, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkv274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538799PMC
August 2015

Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished.

Proc Natl Acad Sci U S A 2015 Jul 12;112(28):E3635-6. Epub 2015 Jun 12.

Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, NY 11794

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http://dx.doi.org/10.1073/pnas.1507710112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507201PMC
July 2015

Effects of the yeast RNA-binding protein Whi3 on the half-life and abundance of CLN3 mRNA and other targets.

PLoS One 2013 30;8(12):e84630. Epub 2013 Dec 30.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084630PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875557PMC
February 2015

Measurement of average decoding rates of the 61 sense codons in vivo.

Elife 2014 Oct 27;3. Epub 2014 Oct 27.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, United States.

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http://dx.doi.org/10.7554/eLife.03735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371865PMC
October 2014

Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice.

Proc Natl Acad Sci U S A 2013 Jun 20;110(23):9481-6. Epub 2013 May 20.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1073/pnas.1307473110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677463PMC
June 2013

Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design.

Proc Natl Acad Sci U S A 2012 Sep 10;109(36):14301-7. Epub 2012 Aug 10.

Department of Molecular Genetics and Microbiology and Computer Science, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1073/pnas.1211484109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437848PMC
September 2012

Repression of meiotic genes by antisense transcription and by Fkh2 transcription factor in Schizosaccharomyces pombe.

PLoS One 2012 6;7(1):e29917. Epub 2012 Jan 6.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029917PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253116PMC
May 2012

The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle.

Genome Biol 2010 23;11(6):R67. Epub 2010 Jun 23.

Departament de Ciències Mèdiques Bàsiques, Institut de Recerca Biomèdica de Lleida, Universitat de Lleida, Montserrat Roig 2, 25008 Lleida, Spain.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2010-11-6-r67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911115PMC
November 2010

Live attenuated influenza virus vaccines by computer-aided rational design.

Nat Biotechnol 2010 Jul 13;28(7):723-6. Epub 2010 Jun 13.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.

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http://dx.doi.org/10.1038/nbt.1636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902615PMC
July 2010

King of the castle: competition between repressors and activators on the Mcm1 platform.

Mol Cell 2010 Apr;38(1):1-2

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765100024
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http://dx.doi.org/10.1016/j.molcel.2010.03.011DOI Listing
April 2010

Phase Coupled Meta-analysis: sensitive detection of oscillations in cell cycle gene expression, as applied to fission yeast.

BMC Genomics 2009 Sep 17;10:440. Epub 2009 Sep 17.

Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-10-440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753555PMC
September 2009

Recruitment of Cln3 cyclin to promoters controls cell cycle entry via histone deacetylase and other targets.

PLoS Biol 2009 Sep 8;7(9):e1000189. Epub 2009 Sep 8.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.

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http://dx.plos.org/10.1371/journal.pbio.1000189
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http://dx.doi.org/10.1371/journal.pbio.1000189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730028PMC
September 2009

Bck2 is a phase-independent activator of cell cycle-regulated genes in yeast.

Cell Cycle 2009 Jan;8(2):239-52

Departament de Ciències Mèdiques Bàsiques, Institut the Recerca Biomèdica de Lleida, Universitat de Lleida, Lleida, Spain.

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http://dx.doi.org/10.4161/cc.8.2.7543DOI Listing
January 2009

TgI4 lipase: a big fat target for cell-cycle entry.

Authors:
Bruce Futcher

Mol Cell 2009 Jan;33(2):143-4

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.01.003DOI Listing
January 2009

Cdc7-Dbf4 regulates NDT80 transcription as well as reductional segregation during budding yeast meiosis.

Mol Biol Cell 2008 Nov 3;19(11):4956-67. Epub 2008 Sep 3.

Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794-5215, USA.

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http://dx.doi.org/10.1091/mbc.e08-07-0755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575173PMC
November 2008

Molecular biology: Bound to splice.

Nature 2008 Oct;455(7215):885-6

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http://dx.doi.org/10.1038/455885aDOI Listing
October 2008

Huxley's revenge: cell-cycle entry, positive feedback, and the G1 cyclins.

Mol Cell 2008 Aug;31(3):307-8

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.07.012DOI Listing
August 2008

Virus attenuation by genome-scale changes in codon pair bias.

Science 2008 Jun;320(5884):1784-7

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1126/science.1155761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754401PMC
June 2008

Cyclins in meiosis: lost in translation.

Authors:
Bruce Futcher

Dev Cell 2008 May;14(5):644-5

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1016/j.devcel.2008.04.009DOI Listing
May 2008

The size of the nucleus increases as yeast cells grow.

Mol Biol Cell 2007 Sep 27;18(9):3523-32. Epub 2007 Jun 27.

Department of Medical Genetics and Microbiology, University of Toronto, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1091/mbc.e06-10-0973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951755PMC
September 2007

Roles of the CDK phosphorylation sites of yeast Cdc6 in chromatin binding and rereplication.

Mol Biol Cell 2007 Apr 31;18(4):1324-36. Epub 2007 Jan 31.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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http://dx.doi.org/10.1091/mbc.e06-06-0544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838967PMC
April 2007

Meta-analysis based on control of false discovery rate: combining yeast ChIP-chip datasets.

Bioinformatics 2006 Oct 14;22(20):2516-22. Epub 2006 Aug 14.

Department of Computer Science, Stony Brook University, NY 11794, USA.

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http://dx.doi.org/10.1093/bioinformatics/btl439DOI Listing
October 2006

Metabolic cycle, cell cycle, and the finishing kick to Start.

Authors:
Bruce Futcher

Genome Biol 2006 26;7(4):107. Epub 2006 Apr 26.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1186/gb-2006-7-4-107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557985PMC
September 2006

Copy correction and concerted evolution in the conservation of yeast genes.

Genetics 2005 Aug 23;170(4):1501-13. Epub 2005 May 23.

Department of Computer Science, Stony Brook University, Stony Brook, New York 11794, USA.

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http://dx.doi.org/10.1534/genetics.103.025940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449775PMC
August 2005

The cell cycle-regulated genes of Schizosaccharomyces pombe.

PLoS Biol 2005 Jul 28;3(7):e225. Epub 2005 Jun 28.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.

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http://dx.doi.org/10.1371/journal.pbio.0030225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157095PMC
July 2005

Identifying combinatorial regulation of transcription factors and binding motifs.

Genome Biol 2004 28;5(8):R56. Epub 2004 Jul 28.

Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1186/gb-2004-5-8-r56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC507881PMC
February 2005

Growth rate and cell size modulate the synthesis of, and requirement for, G1-phase cyclins at start.

Mol Cell Biol 2004 Dec;24(24):10802-13

Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.

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http://dx.doi.org/10.1128/MCB.24.24.10802-10813.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533974PMC
December 2004

Transcriptional regulatory networks and the yeast cell cycle.

Authors:
Bruce Futcher

Curr Opin Cell Biol 2002 Dec;14(6):676-83

Department of Molecular Genetics and Microbiology, Life Science Building, University of Stony Brook, Stony Brook, NY 11794-5222, USA.

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http://dx.doi.org/10.1016/s0955-0674(02)00391-5DOI Listing
December 2002

Biogenesis of yeast telomerase depends on the importin mtr10.

Mol Cell Biol 2002 Sep;22(17):6046-55

Department of Molecular Genetics and Microbiology, State University of New York, Stony Brook, New York 11794-5222, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134008PMC
http://dx.doi.org/10.1128/mcb.22.17.6046-6055.2002DOI Listing
September 2002

The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6.

Mol Cell Biol 2002 Jun;22(12):4402-18

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC133883PMC
http://dx.doi.org/10.1128/mcb.22.12.4402-4418.2002DOI Listing
June 2002