Publications by authors named "Bruce Blumberg"

100Publications

Mechanisms by Which Membrane and Nuclear ER Alpha Inhibit Adipogenesis in Cells Isolated From Female Mice.

Endocrinology 2020 Nov;161(11)

Division of Endocrinology, Department of Veterans Affairs Medical Center, Long Beach, Long Beach, California, USA.

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http://dx.doi.org/10.1210/endocr/bqaa175DOI Listing
November 2020

Agrochemicals and obesity.

Mol Cell Endocrinol 2020 09 30;515:110926. Epub 2020 Jun 30.

Department of Developmental and Cell Biology, University of California, Irvine, CA, 92697-2300, USA; Department of Pharmaceutical Sciences, University of California, Irvine, CA, USA; Department of Biomedical Engineering, University of California, Irvine, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2020.110926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484009PMC
September 2020

Environmental Obesogens and Their Impact on Susceptibility to Obesity: New Mechanisms and Chemicals.

Endocrinology 2020 03;161(3)

Department of Developmental and Cell Biology, University of California Irvine, Irvine, California.

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http://dx.doi.org/10.1210/endocr/bqaa024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060764PMC
March 2020

Transgenerational Self-Reconstruction of Disrupted Chromatin Organization After Exposure To An Environmental Stressor in Mice.

Sci Rep 2019 09 10;9(1):13057. Epub 2019 Sep 10.

Department of Developmental and Cell Biology, University of California, Irvine, 2011 Biological Sciences 3, Irvine, 92697-2300, USA.

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http://dx.doi.org/10.1038/s41598-019-49440-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736928PMC
September 2019

Znf703 is a novel RA target in the neural plate border.

Sci Rep 2019 06 4;9(1):8275. Epub 2019 Jun 4.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, California, Irvine, 92697-2300, USA.

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http://dx.doi.org/10.1038/s41598-019-44722-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547707PMC
June 2019

Current Research Approaches and Challenges in the Obesogen Field.

Front Endocrinol (Lausanne) 2019 22;10:167. Epub 2019 Mar 22.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States.

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http://dx.doi.org/10.3389/fendo.2019.00167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438851PMC
March 2019

Genetics professionals' attitudes toward prenatal exome sequencing.

J Genet Couns 2019 04 19;28(2):229-239. Epub 2019 Mar 19.

Center for Genetic Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1002/jgc4.1112DOI Listing
April 2019

Transgenerational effects of obesogens.

Basic Clin Pharmacol Toxicol 2019 Aug 10;125 Suppl 3:44-57. Epub 2019 Apr 10.

Department of Developmental and Cell Biology, University of California, Irvine, California.

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http://dx.doi.org/10.1111/bcpt.13214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708505PMC
August 2019

Tetrabromobisphenol-A Promotes Early Adipogenesis and Lipogenesis in 3T3-L1 Cells.

Toxicol Sci 2018 Dec;166(2):332-344

National Toxicology Program Laboratory (NTPL), Division of the National Toxicology Program, National Institutes of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709.

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http://dx.doi.org/10.1093/toxsci/kfy209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260163PMC
December 2018

RARγ is required for mesodermal gene expression prior to gastrulation in .

Development 2018 09 17;145(18). Epub 2018 Sep 17.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, 92697-2300, USA

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http://dx.doi.org/10.1242/dev.147769DOI Listing
September 2018

Environmental Obesogens: Mechanisms and Controversies.

Annu Rev Pharmacol Toxicol 2019 01 25;59:89-106. Epub 2018 Jul 25.

Department of Developmental and Cell Biology, Department of Pharmaceutical Sciences, and Department of Biomedical Engineering, University of California, Irvine, California 92697, USA; email:

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http://dx.doi.org/10.1146/annurev-pharmtox-010818-021304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559802PMC
January 2019

Retinoid X Receptor Activation During Adipogenesis of Female Mesenchymal Stem Cells Programs a Dysfunctional Adipocyte.

Endocrinology 2018 08;159(8):2863-2883

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California.

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http://dx.doi.org/10.1210/en.2018-00056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669823PMC
August 2018

Effects of Perinatal Exposure to Dibutyltin Chloride on Fat and Glucose Metabolism in Mice, and Molecular Mechanisms, .

Environ Health Perspect 2018 05 21;126(5):057006. Epub 2018 May 21.

Department of Developmental and Cell Biology, University of California, Irvine, California, USA.

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http://dx.doi.org/10.1289/EHP3030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072003PMC
May 2018

Exploring the Issues Surrounding Clinical Exome Sequencing in the Prenatal Setting.

J Genet Couns 2018 09 10;27(5):1228-1237. Epub 2018 Mar 10.

Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, 645 N. Michigan Avenue, Suite 630, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1007/s10897-018-0245-5DOI Listing
September 2018

Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice.

Nat Commun 2017 12 8;8(1):2012. Epub 2017 Dec 8.

Department of Developmental and Cell Biology, University of California, 2011 Biological Sciences 3, Irvine, CA, 92697-2300, USA.

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http://dx.doi.org/10.1038/s41467-017-01944-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722856PMC
December 2017

Innovative partnerships to advance public health training in community-based academic residency programs.

Adv Med Educ Pract 2017 5;8:703-706. Epub 2017 Oct 5.

Graduate Medical Education, Kaiser Permanente Northern California, Oakland, CA, USA.

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http://dx.doi.org/10.2147/AMEP.S135834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635850PMC
October 2017

Retinoid X Receptor Activation Alters the Chromatin Landscape To Commit Mesenchymal Stem Cells to the Adipose Lineage.

Endocrinology 2017 10;158(10):3109-3125

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697-2300.

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http://dx.doi.org/10.1210/en.2017-00348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659689PMC
October 2017

Endocrine Disruptors and Health Effects in Africa: A Call for Action.

Environ Health Perspect 2017 08 22;125(8):085005. Epub 2017 Aug 22.

Division of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services , Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1289/EHP1774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783641PMC
August 2017

Coupling clinical exome sequencing with functional characterization studies to diagnose a patient with familial Mediterranean fever and haploinsufficiency syndromes.

Clin Case Rep 2017 06 18;5(6):833-840. Epub 2017 Apr 18.

UCLA Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California, Los Angeles Los Angeles California.

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http://dx.doi.org/10.1002/ccr3.904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458005PMC
June 2017

RARβ2 is required for vertebrate somitogenesis.

Development 2017 06 21;144(11):1997-2008. Epub 2017 Apr 21.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, CA 92697-2300, USA

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http://dx.doi.org/10.1242/dev.144345DOI Listing
June 2017

Reply to "Comment on 'On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens'".

Environ Health Perspect 2017 01;125(1):A12-A14

Department of Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1289/EHP1122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224935PMC
January 2017

The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPARγ in Xenopus tropicalis.

Toxicol Appl Pharmacol 2017 Jan 25;314:91-97. Epub 2016 Nov 25.

State Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2016.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183475PMC
January 2017

Reply.

Am J Obstet Gynecol 2016 10 27;215(4):533. Epub 2016 May 27.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2016.05.030DOI Listing
October 2016

Obesogens: an emerging threat to public health.

Am J Obstet Gynecol 2016 05 29;214(5):559-65. Epub 2016 Jan 29.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2016.01.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851574PMC
May 2016

On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens.

Environ Health Perspect 2016 08 13;124(8):1214-26. Epub 2016 Jan 13.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California, USA.

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http://dx.doi.org/10.1289/ehp.1510352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977052PMC
August 2016

Membrane and nuclear estrogen receptor α collaborate to suppress adipogenesis but not triglyceride content.

FASEB J 2016 Jan 15;30(1):230-40. Epub 2015 Sep 15.

*Division of Endocrinology, Veterans Affairs Medical Center, Long Beach, California, USA; Department of Developmental and Cell Biology, Department of Medicine, and Department of Biochemistry, University of California, Irvine, Irvine, California, USA

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http://dx.doi.org/10.1096/fj.15-274878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684544PMC
January 2016

High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype-Phenotype Correlation.

Hum Mutat 2015 Nov 21;36(11):1052-63. Epub 2015 Aug 21.

Department of Genetics, Medical Genomics Laboratory, University of Alabama at Birmingham, Birmingham, Alabama.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049609PMC
http://dx.doi.org/10.1002/humu.22832DOI Listing
November 2015

Looking at Graduate Medical Education Through a Different Lens: A Health Care System's Perspective.

Acad Med 2015 Sep;90(9):1231-5

B.M. Roemer is executive director of medical education implementation strategy, Kaiser Permanente Program Office, Oakland, California. T. Azevedo is associate institutional director of graduate medical education, Kaiser Permanente Northern California, Oakland, California. B. Blumberg is institutional director of graduate medical education, Kaiser Permanente Northern California, Oakland, California.

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http://dx.doi.org/10.1097/ACM.0000000000000828DOI Listing
September 2015

Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage.

PLoS One 2015 6;10(3):e0119177. Epub 2015 Mar 6.

Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan; Department of Anti-aging Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1241, Japan.

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http://blumberg-serv.bio.uci.edu/reprints/azuma-2015.pdf
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http://dx.plos.org/10.1371/journal.pone.0119177
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119177PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352085PMC
January 2016

Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union.

J Clin Endocrinol Metab 2015 Apr 5;100(4):1278-88. Epub 2015 Mar 5.

Department of Chemistry and Biology (J.L.), Institute for Environmental Studies, VU University, 1081 HV Amsterdam, The Netherlands; London School of Tropical Hygiene (T.F.), London WC1E 7HT, United Kingdom; Environmental Risk and Health (E.G.), Flemish Institute for Technological Research, 2400 Mol, Belgium; School of Medicine (M.P.), Universitat Autònoma de Barcelona, 08193 Barcelona, Spain; Hospital del Mar Institute of Medical Research (M.P.), 08003 Barcelona, Spain; Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP) (M.P.), 28029 Madrid, Spain; Department of Developmental and Cell Biology (B.B.), University of California, Irvine, Irvine, California 92697; National Institute of Environmental Health Sciences (J.J.H.), Research Triangle Park, North Carolina 27709; New York University (NYU) School of Medicine (L.T.), New York, New York 10016; NYU Wagner School of Public Service (L.T.), New York, New York 10012; NYU Steinhardt School of Culture, Education, and Human Development (L.T.), Department of Nutrition, Food & Public Health, New York, New York 10003; and NYU Global Institute of Public Health (L.T.), New York, New York 10003.

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http://dx.doi.org/10.1210/jc.2014-4326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399302PMC
April 2015

Retinoic acid signaling and neuronal differentiation.

Cell Mol Life Sci 2015 Apr 6;72(8):1559-76. Epub 2015 Jan 6.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, 92697-2300, USA.

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http://dx.doi.org/10.1007/s00018-014-1815-9DOI Listing
April 2015

Transgenerational effects of obesogens and the obesity epidemic.

Curr Opin Pharmacol 2014 Dec;19:153-8

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, Irvine, CA 92697-2300, USA.

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http://dx.doi.org/10.1016/j.coph.2014.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297575PMC
December 2014

Andrés Carrasco (1946-2014).

Authors:
Bruce Blumberg

Dev Biol 2014 Sep;393(1):1-2

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http://dx.doi.org/10.1016/j.ydbio.2014.07.001DOI Listing
September 2014

Transgenerational inheritance of prenatal obesogen exposure.

Mol Cell Endocrinol 2014 Dec 16;398(1-2):31-5. Epub 2014 Sep 16.

Department of Developmental and Cell Biology, University of California, 2011 Biological Sciences 3, Irvine, CA 92697-2300, United States; Department of Pharmaceutical Sciences, University of California, Irvine, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262625PMC
December 2014

Creating a longitudinal integrated clerkship with mutual benefits for an academic medical center and a community health system.

Perm J 2014 ;18(2):50-6

Professor of Clinical Family and Community Medicine at the University of California, San Francisco and the Permanente Medical Group Teaching Chair for Primary Care.

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http://dx.doi.org/10.7812/TPP/13-137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022558PMC
December 2014

Active repression by RARγ signaling is required for vertebrate axial elongation.

Development 2014 Jun 12;141(11):2260-70. Epub 2014 May 12.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, CA 92697-2300, USA Department of Pharmaceutical Sciences, University of California, Irvine, CA 92697-2300, USA

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http://dx.doi.org/10.1242/dev.103705DOI Listing
June 2014

Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47.

Environ Sci Technol 2014 Apr 11;48(7):4110-9. Epub 2014 Mar 11.

Institute for Environmental Studies, VU University Amsterdam , Amsterdam, 1081HV, The Netherlands.

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http://pubs.acs.org/doi/10.1021/es405524b
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http://dx.doi.org/10.1021/es405524bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983330PMC
April 2014

Reprint of "In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective".

Toxicol Lett 2014 Oct 28;230(2):314-21. Epub 2013 Nov 28.

Center for Occupational and Environmental Health, Department of Medicine, 100 Theory Drive, Suite 100, University of California Irvine, Irvine, CA 92617, USA; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92697-2300, USA; Program in Public Health, University of California Irvine, Irvine, CA 92697-3957, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2013.11.017DOI Listing
October 2014

In utero exposure to benzo[a]pyrene increases adiposity and causes hepatic steatosis in female mice, and glutathione deficiency is protective.

Toxicol Lett 2013 Nov 6;223(2):260-7. Epub 2013 Oct 6.

Center for Occupational and Environmental Health, Department of Medicine, 100 Theory Drive, Suite 100, University of California Irvine, Irvine, CA 92617, USA.

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http://dx.doi.org/10.1016/j.toxlet.2013.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856224PMC
November 2013

ERF and ETV3L are retinoic acid-inducible repressors required for primary neurogenesis.

Development 2013 Aug 3;140(15):3095-106. Epub 2013 Jul 3.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, CA 92697-2300, USA.

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http://dx.doi.org/10.1242/dev.093716DOI Listing
August 2013

The obesogenic effect of high fructose exposure during early development.

Nat Rev Endocrinol 2013 Aug 4;9(8):494-500. Epub 2013 Jun 4.

Department of Preventive Medicine and Childhood Obesity Research Centre, University of Southern California, 2250 Alcazar Street, Los Angeles, CA 90089, USA.

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http://www.nature.com/articles/nrendo.2013.108
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http://dx.doi.org/10.1038/nrendo.2013.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916951PMC
August 2013

Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice.

Environ Health Perspect 2013 Mar 15;121(3):359-66. Epub 2013 Jan 15.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1289/ehp.1205701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621201PMC
March 2013

Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ).

Environ Health Perspect 2012 Dec 22;120(12):1720-6. Epub 2012 Sep 22.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1289/ehp.1205383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548286PMC
December 2012

Bisphenol A diglycidyl ether induces adipogenic differentiation of multipotent stromal stem cells through a peroxisome proliferator-activated receptor gamma-independent mechanism.

Environ Health Perspect 2012 Jul 25;120(7):984-9. Epub 2012 May 25.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1289/ehp.1205063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404682PMC
July 2012

Predicting later-life outcomes of early-life exposures.

Environ Health Perspect 2012 Oct 6;120(10):1353-61. Epub 2012 Jun 6.

Department of Pathology and Laboratory Medicine, Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dels.nas.edu/resources/static-assets/materials-based-
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http://ehp.niehs.nih.gov/1204934
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http://dx.doi.org/10.1289/ehp.1204934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491941PMC
October 2012

The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver.

Mol Endocrinol 2012 Jun 11;26(6):916-25. Epub 2012 Apr 11.

Developmental and Cell Biology, University of California, Irvine, CA 92697-2300, USA.

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http://dx.doi.org/10.1210/me.2011-1303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355537PMC
June 2012

Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence.

J Toxicol Sci 2012 ;37(2):373-80

Division of Cellular and Molecular Toxicology, Biological Safety Research Center, National Institute of Health Sciences, Tokyo, Japan.

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http://dx.doi.org/10.2131/jts.37.373DOI Listing
August 2012

RIPPLY3 is a retinoic acid-inducible repressor required for setting the borders of the pre-placodal ectoderm.

Development 2012 Mar;139(6):1213-24

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, CA 92697-2300, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.071456
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http://dx.doi.org/10.1242/dev.071456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283127PMC
March 2012

Endocrine disrupting chemicals and disease susceptibility.

J Steroid Biochem Mol Biol 2011 Nov 27;127(3-5):204-15. Epub 2011 Aug 27.

National Institute of Environmental Health Sciences, Division of Extramural Research and Training, Cellular, Organ and Systems Pathobiology Branch, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.jsbmb.2011.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220783PMC
November 2011

Endocrine disrupting chemicals.

J Steroid Biochem Mol Biol 2011 Oct 4;127(1-2):1-3. Epub 2011 Aug 4.

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https://linkinghub.elsevier.com/retrieve/pii/S09600760110015
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http://dx.doi.org/10.1016/j.jsbmb.2011.07.012DOI Listing
October 2011

B-1 cell lymphoma in mice lacking the steroid and xenobiotic receptor, SXR.

Mol Endocrinol 2011 Jun 24;25(6):933-43. Epub 2011 Mar 24.

Developmental and Cell Biology, University of California, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1210/me.2010-0486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100607PMC
June 2011

Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity.

Birth Defects Res C Embryo Today 2011 Mar;93(1):34-50

Department of Developmental and Cell Biology, University of California, Irvine, 92697-2300, USA.

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http://doi.wiley.com/10.1002/bdrc.20197
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http://dx.doi.org/10.1002/bdrc.20197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919125PMC
March 2011

The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes.

J Steroid Biochem Mol Biol 2011 Oct 21;127(1-2):9-15. Epub 2011 Mar 21.

Department of Developmental and Cell Biology, University of California, Irvine, CA 92697-2300, United States.

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http://dx.doi.org/10.1016/j.jsbmb.2011.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281769PMC
October 2011

Minireview: PPARγ as the target of obesogens.

J Steroid Biochem Mol Biol 2011 Oct 18;127(1-2):4-8. Epub 2011 Jan 18.

Department of Developmental and Cell Biology, University of California, Irvine, CA 92697-2300, United States.

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http://dx.doi.org/10.1016/j.jsbmb.2011.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116997PMC
October 2011

Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone resorption.

J Endocrinol 2010 Dec 27;207(3):257-63. Epub 2010 Sep 27.

Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

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http://dx.doi.org/10.1677/JOE-10-0208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476281PMC
December 2010

Designing green oxidation catalysts for purifying environmental waters.

J Am Chem Soc 2010 Jul;132(28):9774-81

Department of Chemistry, Institute of Green Science, Mellon Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1021/ja102524vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925145PMC
July 2010

The dynamic genome of Hydra.

Nature 2010 Mar 14;464(7288):592-6. Epub 2010 Mar 14.

US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA.

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http://dx.doi.org/10.1038/nature08830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479502PMC
March 2010

Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes.

Mol Endocrinol 2010 Mar 16;24(3):526-39. Epub 2010 Feb 16.

Department of Developmental and Cell Biology, 2011 Biological Sciences 3, University of California, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1210/me.2009-0261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840805PMC
March 2010

Endocrine disrupters as obesogens.

Mol Cell Endocrinol 2009 May 9;304(1-2):19-29. Epub 2009 Mar 9.

Department of Developmental & Cell Biology, University of California Irvine, 92697-2300, USA.

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http://dx.doi.org/10.1016/j.mce.2009.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713042PMC
May 2009

Minireview: the case for obesogens.

Mol Endocrinol 2009 Aug 16;23(8):1127-34. Epub 2009 Apr 16.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1210/me.2008-0485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718750PMC
August 2009

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.

Nucl Recept Signal 2009 16;7:e001. Epub 2009 Jan 16.

Laboratory of Biochemical Genetics and Metabolism, The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1621/nrs.07001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646121PMC
April 2009

Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells.

BMC Cancer 2009 Jan 5;9. Epub 2009 Jan 5.

Department of Developmental and Cell Biology, 5205 McGaugh Hall, University of California, Irvine, CA 92697-2300, USA.

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http://dx.doi.org/10.1186/1471-2407-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631587PMC
January 2009

Subtractive hybridization and construction of cDNA libraries.

Methods Mol Biol 2008 ;461:569-87

Gene Expression Laboratory, Stem Cell Research Center, Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California, USA.

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http://dx.doi.org/10.1007/978-1-60327-483-8_39DOI Listing
January 2009

Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis.

Rev Endocr Metab Disord 2007 Jun;8(2):161-71

Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.

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http://dx.doi.org/10.1007/s11154-007-9049-xDOI Listing
June 2007

Clinical features and management issues in Mowat-Wilson syndrome.

Am J Med Genet A 2006 Dec;140(24):2730-41

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1002/ajmg.a.31530DOI Listing
December 2006

The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor.

Mol Pharmacol 2007 Jan 6;71(1):220-9. Epub 2006 Oct 6.

Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1124/mol.106.029264DOI Listing
January 2007

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia.

J Clin Invest 2006 Jun 11;116(6):1703-12. Epub 2006 May 11.

Department of Pharmaceutics, University of Washington, Seattle, Washington 98195-7610, USA.

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http://dx.doi.org/10.1172/JCI27793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459072PMC
June 2006

Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling.

Endocrinology 2006 Jun 11;147(6 Suppl):S50-5. Epub 2006 May 11.

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1210/en.2005-1129DOI Listing
June 2006

Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates.

Mol Endocrinol 2006 Sep 13;20(9):2141-55. Epub 2006 Apr 13.

Department of Developmental and Cell Biology, University of California Irvine, 2113 McGaugh Hall, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1210/me.2005-0367DOI Listing
September 2006

Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells.

J Biol Chem 2006 Jun 10;281(25):16927-34. Epub 2006 Apr 10.

Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical School, Saitama 350-1241, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M600896200
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http://dx.doi.org/10.1074/jbc.M600896200DOI Listing
June 2006

Brachydactylic multiple delta phalanges plus syndrome.

Am J Med Genet A 2005 Sep;138(1):41-4

Department of Pediatrics, Division of Medical Genetics, University of California San Francisco, 94143-0706, USA.

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http://dx.doi.org/10.1002/ajmg.a.30873DOI Listing
September 2005

New modes of action for endocrine-disrupting chemicals.

Mol Endocrinol 2006 Mar 21;20(3):475-82. Epub 2005 Jul 21.

Department of Developmental and Cell Biology, University of California, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1210/me.2004-0513DOI Listing
March 2006

Learning from and about others: towards using imitation to bootstrap the social understanding of others by robots.

Artif Life 2005 Winter-Spring;11(1-2):31-62

MIT Media Lab, 77 Massachusetts Avenue, NE18, 5th floor, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1162/1064546053278955DOI Listing
May 2005

Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues.

Mol Cell Endocrinol 2005 Feb 23;231(1-2):75-85. Epub 2005 Jan 23.

Department of Pathology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi-ken 980-8575, Japan.

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http://dx.doi.org/10.1016/j.mce.2004.12.005DOI Listing
February 2005

Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway.

J Clin Immunol 2004 Nov;24(6):623-36

Department of Developmental and Cell Biology, University of California, Irvine, California 92697-2300, USA.

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http://dx.doi.org/10.1007/s10875-004-6248-zDOI Listing
November 2004