Publications by authors named "Bronislaw Pytowski"

42Publications

VEGF-C promotes the development of lymphatics in bone and bone loss.

Elife 2018 04 5;7. Epub 2018 Apr 5.

Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, United States.

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http://dx.doi.org/10.7554/eLife.34323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903859PMC
April 2018

Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents.

Pharmacol Ther 2016 08 8;164:204-25. Epub 2016 Jun 8.

Eli Lilly and Company, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2016.06.001DOI Listing
August 2016

Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period.

Circ Res 2014 Feb 15;114(5):806-22. Epub 2014 Jan 15.

From the Department of Anatomy, Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, San Francisco (L.-C.Y., P.B., D.M.M.); Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden (C.T., L.C.-W.); Wihuri Research Institute and Translational Cancer Biology Program, Biomedicum Helsinki and University of Helsinki, Helsinki, Finland (D.T., A.A., K.A.); Department of Pathology, Boston Children's Hospital, Harvard University, MA (S.O.V.), and Department of Cell Biology, ImClone Systems, Eli Lilly and Company, New York (B.P.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.303119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969887PMC
February 2014

Inhibition of VEGFR-3 activation in tumor-draining lymph nodes suppresses the outgrowth of lymph node metastases in the MT-450 syngeneic rat breast cancer model.

Clin Exp Metastasis 2014 Mar 31;31(3):351-65. Epub 2013 Dec 31.

Centre for Biomedicine and Medical Technology Mannheim (CBTM), Medizinische Fakultät Mannheim, Universitätsmedizin Mannheim, Universität Heidelberg, TRIDOMUS-Gebäude Haus C, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s10585-013-9633-2DOI Listing
March 2014

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.

Nature 2012 Mar 18;484(7392):110-4. Epub 2012 Mar 18.

Max Planck Institute for Molecular Biomedicine, Department of Tissue Morphogenesis, D-48149 Münster, Germany.

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http://dx.doi.org/10.1038/nature10908DOI Listing
March 2012

Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.

J Exp Med 2010 Sep 13;207(10):2255-69. Epub 2010 Sep 13.

Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.1084/jem.20100559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947063PMC
September 2010

Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.

Circulation 2010 Mar 15;121(12):1413-22. Epub 2010 Mar 15.

Cardiopulmonary Research Group, Transplantation Laboratory, Haartman Institute, FI-00014 University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.910703DOI Listing
March 2010

Vascular endothelial growth factor receptor 2 (VEGFR-2) functions to promote uterine decidual angiogenesis during early pregnancy in the mouse.

Endocrinology 2009 Aug 30;150(8):3845-54. Epub 2009 Apr 30.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1210/en.2008-1207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717882PMC
August 2009

Suppression of prostate cancer nodal and systemic metastasis by blockade of the lymphangiogenic axis.

Cancer Res 2008 Oct;68(19):7828-37

Department of Molecular and Medical Pharmacology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095-1738, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800077PMC
October 2008

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.

Nature 2008 Jul 25;454(7204):656-60. Epub 2008 Jun 25.

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki and the Haartman Institute University of Helsinki, PO Box 63 (Haartmaninkatu 8), 00014 Helsinki, Finland.

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http://dx.doi.org/10.1038/nature07083DOI Listing
July 2008

The resolution of lymphedema by interstitial flow in the mouse tail skin.

Am J Physiol Heart Circ Physiol 2008 Mar 18;294(3):H1326-34. Epub 2008 Jan 18.

Biomedical Engineering Department, Michigan Technological University, Houghton, MI 49931, USA.

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http://dx.doi.org/10.1152/ajpheart.00900.2007DOI Listing
March 2008

Blockade of VEGFR3-signalling specifically inhibits lymphangiogenesis in inflammatory corneal neovascularisation.

Graefes Arch Clin Exp Ophthalmol 2008 Jan 2;246(1):115-9. Epub 2007 Oct 2.

Department of Ophthalmology, University of Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00417-007-0683-5DOI Listing
January 2008

Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth.

Cancer Res 2007 Jan;67(2):593-9

Molecular/Cancer Biology Research Program and Ludwig Institute for Cancer Research, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3567DOI Listing
January 2007

Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis.

FASEB J 2007 Apr 8;21(4):1003-12. Epub 2007 Jan 8.

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1096/fj.06-6656comDOI Listing
April 2007

Regulation of lymphatic capillary regeneration by interstitial flow in skin.

Am J Physiol Heart Circ Physiol 2007 May 22;292(5):H2176-83. Epub 2006 Dec 22.

Biomedical Engineering Department, Michigan Technological University, Houghton, MI 49931, USA.

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http://dx.doi.org/10.1152/ajpheart.01011.2006DOI Listing
May 2007

Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision.

Proc Natl Acad Sci U S A 2006 Jul 18;103(30):11405-10. Epub 2006 Jul 18.

Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0506112103
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http://dx.doi.org/10.1073/pnas.0506112103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544098PMC
July 2006

Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection.

J Biol Chem 2005 Jul 4;280(28):26216-24. Epub 2005 May 4.

Division of Experimental Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M411392200DOI Listing
July 2005

Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development.

FASEB J 2004 Oct;18(13):1507-15

Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://www.fasebj.org/doi/10.1096/fj.03-1276com
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http://dx.doi.org/10.1096/fj.03-1276comDOI Listing
October 2004

Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity.

Nat Med 2004 Aug 4;10(8):813-5. Epub 2004 Jul 4.

Laboratory of Immunology, Schepens Eye Research Institute and the Massachusetts Eye and Ear Infirmary and Department of Ophthalmology, Harvard Medical School, 20 Staniford Street, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nm1078DOI Listing
August 2004