Publications by authors named "Britta Engelhardt"

100Publications

T Cell-Mediated Transport of Polymer Nanoparticles across the Blood-Brain Barrier.

Adv Healthc Mater 2020 Nov 25:e2001375. Epub 2020 Nov 25.

École Polytechnique Fédérale de Lausanne (EPFL), Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques, Laboratoire des Polymères, Bâtiment MXD, Station 12, Lausanne, CH-1015, Switzerland.

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http://dx.doi.org/10.1002/adhm.202001375DOI Listing
November 2020

Brain Barriers and Multiple Sclerosis: Novel Treatment Approaches from a Brain Barriers Perspective.

Handb Exp Pharmacol 2020 Nov 26. Epub 2020 Nov 26.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1007/164_2020_407DOI Listing
November 2020

Microglia Get a Little Help from "Th"-eir Friends.

Immunity 2020 Sep;53(3):484-486

Theodor Kocher Institute, University of Bern, Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.08.011DOI Listing
September 2020

Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation.

Vasc Biol 2020 20;2(1):H1-H18. Epub 2020 Mar 20.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1530/VB-19-0033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439848PMC
March 2020

Oligomeric Forms of Human Amyloid-Beta(1-42) Inhibit Antigen Presentation.

Front Immunol 2020 5;11:1029. Epub 2020 Jun 5.

Institute for Regenerative Medicine - IREM, University of Zurich, Schlieren, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2020.01029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290131PMC
June 2020

CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin.

Cell Host Microbe 2020 07 3;28(1):69-78.e6. Epub 2020 Jun 3.

Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse-Faculty, University of Bern, 3012 Bern, Switzerland; COMPATH, Vetsuisse-Faculty & Faculty of Medicine, University of Bern, 3012 Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.05.003DOI Listing
July 2020

Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis.

J Neuroinflammation 2020 Jan 8;17(1). Epub 2020 Jan 8.

Department of Neurology, Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Freiburgstrasse, 3010, Bern, Switzerland.

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http://dx.doi.org/10.1186/s12974-019-1677-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951012PMC
January 2020

Sleep enhances numbers and function of monocytes and improves bacterial infection outcome in mice.

Brain Behav Immun 2020 07 3;87:329-338. Epub 2020 Jan 3.

Department of Internal Medicine II, University of Tübingen, 72076 Tübingen, Germany; Core Facility Flow Cytometry of the Medical Faculty Tübingen, University of Tübingen, 72076 Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2020.01.001DOI Listing
July 2020

Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection.

J Neuroinflammation 2019 Nov 21;16(1):232. Epub 2019 Nov 21.

Pediatric Infectious Diseases, University Children's Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1186/s12974-019-1626-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868812PMC
November 2019

Structure and Junctional Complexes of Endothelial, Epithelial and Glial Brain Barriers.

Int J Mol Sci 2019 Oct 29;20(21). Epub 2019 Oct 29.

Theodor Kocher Institute, University of Bern, 3012 Bern, Switzerland.

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http://dx.doi.org/10.3390/ijms20215372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862204PMC
October 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

CD49d/CD29-integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation.

Eur J Immunol 2019 11 26;49(11):2030-2043. Epub 2019 Jul 26.

Centre de Physiopathologie de Toulouse Purpan (CPTP), Université de Toulouse, INSERM, CNRS, UPS, Toulouse, France.

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http://dx.doi.org/10.1002/eji.201948086DOI Listing
November 2019

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo.

J Vis Exp 2019 03 26(145). Epub 2019 Mar 26.

Theodor Kocher Institute, University of Bern;

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http://dx.doi.org/10.3791/59249DOI Listing
March 2019

Ischemia-reperfusion injury in stroke: impact of the brain barriers and brain immune privilege on neutrophil function.

Ther Adv Neurol Disord 2018 27;11:1756286418794184. Epub 2018 Aug 27.

Theodor Kocher Institute, University of Bern, Freiestrasse 1, Bern 3012, Switzerland.

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http://dx.doi.org/10.1177/1756286418794184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111395PMC
August 2018

Lack of junctional adhesion molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis.

Brain Behav Immun 2018 10 18;73:3-20. Epub 2018 Jun 18.

Theodor Kocher Institute, University of Bern, Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2018.06.014DOI Listing
October 2018

Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod.

CNS Neurosci Ther 2018 10 13;24(10):984-986. Epub 2018 Jun 13.

Department of Neurology, Bern University Hospital and University of Bern, Switzerland.

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http://dx.doi.org/10.1111/cns.12992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489842PMC
October 2018

ICAM-1 C57BL/6 Mice Are Not Protected from Experimental Ischemic Stroke.

Transl Stroke Res 2018 12 4;9(6):608-621. Epub 2018 Feb 4.

Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland.

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http://dx.doi.org/10.1007/s12975-018-0612-4DOI Listing
December 2018

Cluster: barriers of the central nervous system.

Acta Neuropathol 2018 03;135(3):307-310

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1007/s00401-018-1816-0DOI Listing
March 2018

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease.

Acta Neuropathol 2018 03 24;135(3):337-361. Epub 2018 Jan 24.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1007/s00401-018-1807-1DOI Listing
March 2018

Immunosenescence in persons with spinal cord injury in relation to urinary tract infections -a cross-sectional study.

Immun Ageing 2017 15;14:22. Epub 2017 Nov 15.

Biomedical Laboratories, Swiss Paraplegic Research, Guido A. Zäch Strasse 4, 6207, Nottwil, Switzerland.

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http://dx.doi.org/10.1186/s12979-017-0103-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688733PMC
November 2017

TNFα blockade mediates bone protection in antigen-induced arthritis by reducing osteoclast precursor supply.

Bone 2018 02 14;107:56-65. Epub 2017 Nov 14.

Department of Rheumatology, Immunology & Allergology, University Hospital, Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.10.020DOI Listing
February 2018

Impaired T-cell migration to the CNS under fingolimod and dimethyl fumarate.

Neurol Neuroimmunol Neuroinflamm 2017 Nov 11;4(6):e401. Epub 2017 Oct 11.

Laboratory of Neuroimmunology (A.M., S.P., M.C., C.G., R.D.P.), Center of Research in Neurosciences, Service of Neurology (M.S., R.D.P.), Department of Clinical Neurosciences, CHUV, Lausanne, Switzerland; and Theodor Kocher Institute (C.B., B.E.), University of Bern, Switzerland.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639463PMC
November 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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http://doi.wiley.com/10.1002/eji.201646632
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http://dx.doi.org/10.1002/eji.201646632DOI Listing
October 2017

The choroid plexus is a key cerebral invasion route for T cells after stroke.

Acta Neuropathol 2017 12 31;134(6):851-868. Epub 2017 Jul 31.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Feodor-Lynen-Str. 17, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00401-017-1758-yDOI Listing
December 2017

Brain barriers in health and disease.

Neurobiol Dis 2017 11 25;107:1-3. Epub 2017 May 25.

Theodor Kocher Institute, Universitat Bern, Switzerland.

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http://dx.doi.org/10.1016/j.nbd.2017.05.008DOI Listing
November 2017

The movers and shapers in immune privilege of the CNS.

Nat Immunol 2017 02 16;18(2):123-131. Epub 2017 Jan 16.

Neuropathology, Southampton University Hospital, Southampton, UK.

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http://dx.doi.org/10.1038/ni.3666DOI Listing
February 2017

Non-invasive near-infrared fluorescence imaging of the neutrophil response in a mouse model of transient cerebral ischaemia.

J Cereb Blood Flow Metab 2017 Aug 1;37(8):2833-2847. Epub 2016 Jan 1.

1 Institute for Biomedical Engineering, ETH & University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1177/0271678X16676825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536255PMC
August 2017

Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.

Nat Commun 2016 08 31;7:12658. Epub 2016 Aug 31.

Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle Drive, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/ncomms12658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013657PMC
August 2016

Vascular, glial, and lymphatic immune gateways of the central nervous system.

Acta Neuropathol 2016 09 13;132(3):317-38. Epub 2016 Aug 13.

Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1007/s00401-016-1606-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992028PMC
September 2016

Refined clinical scoring in comparative EAE studies does not enhance the chance to observe statistically significant differences.

Eur J Immunol 2016 10 31;46(10):2481-2483. Epub 2016 Aug 31.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/eji.201546272DOI Listing
October 2016

Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis.

Eur J Immunol 2016 09;46(9):2078-90

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/eji.201646485DOI Listing
September 2016

Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments.

Neuropharmacology 2016 06 23;105:341-350. Epub 2016 Jan 23.

Institute of Pharmacology, University of Bern, Inselspital INO-F, CH-3010 Bern, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00283908163003
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http://dx.doi.org/10.1016/j.neuropharm.2016.01.031DOI Listing
June 2016

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke.

Biochim Biophys Acta 2016 03 23;1862(3):461-71. Epub 2015 Oct 23.

Department of Molecular Cell Biology and Immunology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.10.018DOI Listing
March 2016

Leptomeningeal contrast enhancement and blood-CSF barrier dysfunction in aseptic meningitis.

Neurol Neuroimmunol Neuroinflamm 2015 Dec 15;2(6):e164. Epub 2015 Oct 15.

Department of Neurology (A.A., P.E., A.D.E., M.G., K.S., M.G.H., A.G.), Universitätsmedizin Mannheim, University of Heidelberg, Mannheim, Germany; and Theodor Kocher Institute (B.E.), University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1212/NXI.0000000000000164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608759PMC
December 2015

Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV-induced meningitis.

Eur J Immunol 2016 Jan 2;46(1):104-13. Epub 2015 Nov 2.

Division of Immunology, Department of Biology, University of Konstanz, Konstanz, Germany.

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http://doi.wiley.com/10.1002/eji.201545578
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http://dx.doi.org/10.1002/eji.201545578DOI Listing
January 2016

Wiring the Vascular Network with Neural Cues: A CNS Perspective.

Neuron 2015 Jul;87(2):271-96

Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012 Bern, Switzerland.

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http://dx.doi.org/10.1016/j.neuron.2015.06.038DOI Listing
July 2015

Brain barriers: Crosstalk between complex tight junctions and adherens junctions.

J Cell Biol 2015 May;209(4):493-506

Theodor Kocher Institute, University of Bern, CH-3012 Bern, Switzerland

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http://www.jcb.org/lookup/doi/10.1083/jcb.201412147
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http://dx.doi.org/10.1083/jcb.201412147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442813PMC
May 2015

Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers.

Biomaterials 2015 Jun 27;54:9-20. Epub 2015 Mar 27.

Leibniz-Institut für Molekulare Pharmakologie, Berlin-Buch 13125, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.03.007DOI Listing
June 2015

Investigation of leptomeningeal enhancement in MS: a postcontrast FLAIR MRI study.

Neurology 2015 Feb 23;84(8):770-5. Epub 2015 Jan 23.

From the Department of Neurology (P.E., M.G., K.S., M.E.W., A.A., M.G.H., A.G.), Universitätsmedizin Mannheim, University of Heidelberg, Mannheim, Germany; and Theodor Kocher Institute (B.E.), University of Bern, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000001286DOI Listing
February 2015

Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier.

Eur J Immunol 2015 Apr 23;45(4):1043-58. Epub 2015 Jan 23.

Theodor Kocher Institute, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.

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http://doi.wiley.com/10.1002/eji.201445125
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April 2015

Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases.

J Immunol 2014 Sep 21;193(5):2438-54. Epub 2014 Jul 21.

Centre de Recherche du Centre Hospitalier Universitaire de Québec-Centre Hospitalier de l'Université Laval, Quebec, Quebec G1V 4G2, Canada; Département de Médecine Moléculaire, Faculté de Médecine, Université Laval, Quebec, Quebec G1V 0A6, Canada;

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http://dx.doi.org/10.4049/jimmunol.1400401DOI Listing
September 2014

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells.

PLoS One 2014 17;9(6):e99733. Epub 2014 Jun 17.

CNC - Center of Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal; Biomaterials and Stem Cell-based Therapeutics Laboratory, Biocant - Center of Innovation in Biotechnology, Cantanhede, Portugal.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099733PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061029PMC
February 2015

Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice.

Neuropharmacology 2014 Oct 23;85:314-27. Epub 2014 May 23.

Institute of Pharmacology, University of Bern, Friedbühlstrasse 49, CH-3010 Bern, Switzerland; Pharmazentrum Frankfurt/ZAFES, University Hospital, Goethe University Frankfurt am Main, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2014.05.012DOI Listing
October 2014

PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE.

Eur J Immunol 2014 Aug 11;44(8):2287-94. Epub 2014 May 11.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/eji.201344214DOI Listing
August 2014

Novel insights into the development and maintenance of the blood-brain barrier.

Cell Tissue Res 2014 Mar 4;355(3):687-99. Epub 2014 Mar 4.

Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012, Bern, Switzerland,

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http://dx.doi.org/10.1007/s00441-014-1811-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972432PMC
March 2014

β2 integrin-mediated crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed blood-brain barrier.

J Immunol 2014 Jan 20;192(1):324-37. Epub 2013 Nov 20.

Theodor Kocher Institute, University of Bern, Bern CH-3012, Switzerland.

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http://dx.doi.org/10.4049/jimmunol.1300858DOI Listing
January 2014

Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells.

Proc Natl Acad Sci U S A 2013 Oct 2;110(42):17005-10. Epub 2013 Oct 2.

Department of Molecular Medicine, Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1073/pnas.1316032110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801036PMC
October 2013

Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo.

Fluids Barriers CNS 2013 Jan 21;10(1). Epub 2013 Jan 21.

Theodor Kocher Institute, University of Bern, Bern, 3012, Switzerland.

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http://dx.doi.org/10.1186/2045-8118-10-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560242PMC
January 2013

Going against the tide--how encephalitogenic T cells breach the blood-brain barrier.

J Vasc Res 2012 29;49(6):497-509. Epub 2012 Aug 29.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1159/000341232DOI Listing
January 2013

Capture, crawl, cross: the T cell code to breach the blood-brain barriers.

Trends Immunol 2012 Dec 25;33(12):579-89. Epub 2012 Aug 25.

Theodor Kocher Institute, University of Bern, Freiestrasse 1, CH-3012 Bern, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S14714906120012
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http://dx.doi.org/10.1016/j.it.2012.07.004DOI Listing
December 2012

The anatomical and cellular basis of immune surveillance in the central nervous system.

Nat Rev Immunol 2012 Sep 20;12(9):623-35. Epub 2012 Aug 20.

Neuroinflammation Research Center and Mellen Center for MS Treatment and Research, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://www.nature.com/articles/nri3265
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September 2012

T-cell trafficking in the central nervous system.

Immunol Rev 2012 Jul;248(1):216-27

Institute for Research in Biomedicine, Bellinzona, Switzerland.

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http://dx.doi.org/10.1111/j.1600-065X.2012.01140.xDOI Listing
July 2012

Neuroscience. Blood-brain barrier differentiation.

Science 2011 Dec;334(6063):1652-3

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1126/science.1216853DOI Listing
December 2011

Caveolin-1 opens endothelial cell junctions by targeting catenins.

Cardiovasc Res 2012 Jan 29;93(1):130-40. Epub 2011 Sep 29.

Institute of Physiology, Medical Faculty of the TU-Dresden, Germany.

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http://dx.doi.org/10.1093/cvr/cvr256DOI Listing
January 2012

β1-integrin/matrix interactions support blood-brain barrier integrity.

J Cereb Blood Flow Metab 2011 Oct 20;31(10):1969-71. Epub 2011 Jul 20.

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http://dx.doi.org/10.1038/jcbfm.2011.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208158PMC
October 2011

Brain infiltration of leukocytes contributes to the pathophysiology of temporal lobe epilepsy.

J Neurosci 2011 Mar;31(11):4037-50

Institute of Pharmacology and Toxicology and Institute of Molecular Cancer Research, University of Zurich, CH-8057 Zurich, Switzerland.

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http://dx.doi.org/10.1523/JNEUROSCI.6210-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623535PMC
March 2011

Tight junctions in brain barriers during central nervous system inflammation.

Antioxid Redox Signal 2011 Sep 25;15(5):1285-303. Epub 2011 May 25.

Theodor Kocher Institute, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1089/ars.2011.3929DOI Listing
September 2011

Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T-cell homing into the CNS.

Eur J Immunol 2010 Dec 11;40(12):3489-98. Epub 2010 Nov 11.

INSERM, U563, Centre de Physiopathologie de Toulouse Purpan, Toulouse, France.

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http://dx.doi.org/10.1002/eji.201040678DOI Listing
December 2010

PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice.

J Neuroimmunol 2011 Mar 3;232(1-2):207-8. Epub 2010 Nov 3.

Theodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, Switzerland.

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http://dx.doi.org/10.1016/j.jneuroim.2010.10.008DOI Listing
March 2011

Alpha4beta1 integrin mediates the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis.

J Immunol 2010 Jun 17;184(12):7196-206. Epub 2010 May 17.

Department of Microbiology and Immunology and Drexel Institute for Biotechnology and Virology Research, Drexel University College of Medicine, Doylestown, PA 18902, USA.

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http://dx.doi.org/10.4049/jimmunol.0901404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999618PMC
June 2010