Publications by authors named "Brion W Murray"

33Publications

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling.

Cell Rep 2020 02;30(6):1935-1950.e8

Tumor Cell Biology, Pfizer Oncology Research & Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.celrep.2020.01.054DOI Listing
February 2020

Countering Breast Cancer's Counterpunch.

Authors:
Brion W Murray

Mol Cancer Ther 2019 10;18(10):1682-1683

Turning Point Therapeutics, San Diego, California

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http://dx.doi.org/10.1158/1535-7163.MCT-19-0875DOI Listing
October 2019

Analysis of Cysteine Redox Post-Translational Modifications in Cell Biology and Drug Pharmacology.

Methods Mol Biol 2017 ;1558:191-212

Oncology Research Unit, Pfizer Worldwide Research and Development, 10770 Science Center Drive, San Diego, CA, 92121, USA.

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http://dx.doi.org/10.1007/978-1-4939-6783-4_9DOI Listing
February 2018

Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance.

Mol Cancer Ther 2016 10 5;15(10):2273-2281. Epub 2016 Aug 5.

Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0300DOI Listing
October 2016

Recent progress on third generation covalent EGFR inhibitors.

Bioorg Med Chem Lett 2016 Apr 23;26(8):1861-8. Epub 2016 Feb 23.

Oncology Research Unit, La Jolla Laboratories, Pfizer Worldwide Research and Development, 10770 Science Center Drive, San Diego, CA 92121, United States.

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http://dx.doi.org/10.1016/j.bmcl.2016.02.067DOI Listing
April 2016

Durability of Kinase-Directed Therapies--A Network Perspective on Response and Resistance.

Mol Cancer Ther 2015 Sep 11;14(9):1975-84. Epub 2015 Aug 11.

Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0088DOI Listing
September 2015

Maleimide-based method for elaboration of cysteine-containing peptide phage libraries.

Methods Mol Biol 2015 ;1248:267-76

Pfizer Worldwide Research and Development, 10646 Science Center Dr, San Diego, CA, 92121, USA.

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http://dx.doi.org/10.1007/978-1-4939-2020-4_18DOI Listing
September 2015

An algebraic model for the kinetics of covalent enzyme inhibition at low substrate concentrations.

Anal Biochem 2015 Sep 27;484:82-90. Epub 2014 Nov 27.

Oncology Research Unit, Pfizer Worldwide Research and Development, La Jolla, Pfizer, San Diego, CA 92121, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00032697140054
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http://dx.doi.org/10.1016/j.ab.2014.11.014DOI Listing
September 2015

Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology.

Front Pharmacol 2014 6;5:224. Epub 2014 Oct 6.

Oncology Research Unit, Pfizer Worldwide Research and Development San Diego, CA, USA.

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http://dx.doi.org/10.3389/fphar.2014.00224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186267PMC
October 2014

Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.

Bioorg Med Chem Lett 2014 Sep 22;24(17):4187-91. Epub 2014 Jul 22.

Oncology Research Unit, Pfizer Worldwide Research & Development, San Diego, CA 92121, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.07.044DOI Listing
September 2014

A simple and efficient maleimide-based approach for peptide extension with a cysteine-containing peptide phage library.

Bioorg Med Chem Lett 2013 Oct 13;23(20):5680-3. Epub 2013 Aug 13.

Pfizer Worldwide Research and Development, San Diego, CA 92121,USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.08.032DOI Listing
October 2013

Substrate-specific conformational regulation of the receptor tyrosine kinase VEGFR2 catalytic domain.

ACS Chem Biol 2013 May 6;8(5):978-86. Epub 2013 Mar 6.

Oncology Research Unit, Pfizer Worldwide Research and Development, 10777 Science Center Drive, San Diego, CA 92121, USA.

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http://pubs.acs.org/doi/10.1021/cb400040z
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http://dx.doi.org/10.1021/cb400040zDOI Listing
May 2013

Protein kinase biochemistry and drug discovery.

Bioorg Chem 2011 Dec 3;39(5-6):192-210. Epub 2011 Aug 3.

Pfizer Worldwide Research and Development, La Jolla, Pfizer Inc., San Diego, CA 92121, United States.

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http://dx.doi.org/10.1016/j.bioorg.2011.07.004DOI Listing
December 2011

Structure-based design of novel human Pin1 inhibitors (II).

Bioorg Med Chem Lett 2010 Apr 14;20(7):2210-4. Epub 2010 Feb 14.

Pfizer Global Research and Development, 10770 Science Center Drive, San Diego, CA 92121, United States.

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http://dx.doi.org/10.1016/j.bmcl.2010.02.033DOI Listing
April 2010

Characterizing the effects of the juxtamembrane domain on vascular endothelial growth factor receptor-2 enzymatic activity, autophosphorylation, and inhibition by axitinib.

Biochemistry 2009 Jul;48(29):7019-31

Pfizer Global Research and Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/bi900522yDOI Listing
July 2009

Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.

Biochemistry 2009 Jun;48(23):5339-49

Pfizer Global Research and Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/bi900438wDOI Listing
June 2009

Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.

Biochemistry 2008 Feb 1;47(8):2617-30. Epub 2008 Feb 1.

Pfizer Global Research and Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/bi702107vDOI Listing
February 2008

Protein-inhibitor complexes analyzed by alkaline capillary LC-MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Oct;825(2):176-85

Pfizer Global Research & Development-La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S157002320500303
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http://dx.doi.org/10.1016/j.jchromb.2005.04.026DOI Listing
October 2005

Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases.

J Am Chem Soc 2004 Feb;126(7):1971-9

CEA, CE-Saclay, Service de Marquage Moléculaire et de Chimie Bioorganique, Bât 547, Département de Biologie Joliot-Curie, 91191 Gif Sur Yvette, France.

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http://dx.doi.org/10.1021/ja037822rDOI Listing
February 2004