Brigitte Strahm

Hematopoietic cell transplantation in chronic granulomatous disease: a study of 712 children and adults.

Blood 2020 Sep;136(10):1201-1211

Department of Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, United Kingdom.

September 2020

Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency.

Leukemia 2020 10 18;34(10):2673-2687. Epub 2020 Jun 18.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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October 2020

Favorable outcomes of hematopoietic stem cell transplantation in children and adolescents with Diamond-Blackfan anemia.

Blood Adv 2020 04;4(8):1760-1769

Robert Debré Hospital, Groupe Hospitalier, Assistance Publique-Hôpitaux de Paris Nord, Université de Paris, Paris, France.

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April 2020

Psychometric properties of the Activities Scale for Kids-performance after allogeneic hematopoietic stem cell transplantation in adolescents and children : Results of a prospective study on behalf of the German-Austrian-Swiss GVHD Consortium.

Authors:

Anita Lawitschka Matthias Brunmair Dorothea Bauer Natalia Zubarovskaya Rosemarie Felder-Puig Brigitte Strahm Peter Bader Gabriele Strauss Michael Albert Irene von Luettichau Hildegard Greinix Daniel Wolff Christina Peters

Wien Klin Wochenschr 2020 Apr 3. Epub 2020 Apr 3.

St. Anna Children's Hospital, SCT-Outpatient & Aftercare Clinic, Medical University Vienna and Children's Cancer Research Institute, Kinderspitalgasse 15, 1090, Vienna, Austria.

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April 2020

Pediatric acute graft-versus-host disease prophylaxis and treatment: surveyed real-life approach reveals dissimilarities compared to published recommendations.

Authors:

Anita Lawitschka Giovanna Lucchini Brigitte Strahm Jean-Hugues Dalle Adriana Balduzzi Brenda Gibson Cristina Diaz De Heredia Jacek Wachowiak Arnaud Dalissier Kim Vettenranta Isaac Yaniv Victoria Bordon Dorothea Bauer Peter Bader Roland Meisel Christina Peters Selim Corbacioglu

Transpl Int 2020 Jul 2;33(7):762-772. Epub 2020 Apr 2.

Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Hospital Regensburg, Regensburg, Germany.

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July 2020

Correction: Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial.

Leukemia 2020 05;34(5):1486

Department of Pediatrics, Division of Pediatric Hematology and Oncology, University of Düsseldorf, Düsseldorf, Germany.

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May 2020

Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets.

Blood Adv 2019 10;3(20):3143-3156

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.

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October 2019

Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial.

Leukemia 2020 02 2;34(2):613-624. Epub 2019 Oct 2.

Department of Pediatrics, Division of Pediatric Hematology and Oncology, University of Düsseldorf, Düsseldorf, Germany.

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February 2020

Allogeneic hematopoietic stem cell transplantation from unrelated donors is associated with higher infection rates in children with acute lymphoblastic leukemia-A prospective international multicenter trial on behalf of the BFM-SG and the EBMT-PDWP.

Am J Hematol 2019 08 29;94(8):880-890. Epub 2019 May 29.

St. Anna Kinderspital and Children's Cancer Research Institute (CCRI), Department of Paediatrics, Medical University of Vienna, Vienna, Austria.

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August 2019

Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL.

Bone Marrow Transplant 2019 11 14;54(11):1847-1858. Epub 2019 May 14.

Division of Pediatric Stem Cell Therapy, Clinic for Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.

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November 2019

Concise Review: Cheating Death for a Better Transplant.

Authors:

Sehar Afreen Julia Miriam Weiss Brigitte Strahm Miriam Erlacher

Stem Cells 2018 11 1;36(11):1646-1654. Epub 2018 Oct 1.

Faculty of Medicine, Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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November 2018

Low incidence of symptomatic osteonecrosis after allogeneic HSCT in children with high-risk or relapsed ALL - results of the ALL-SCT 2003 trial.

Br J Haematol 2018 10 20;183(1):104-109. Epub 2018 Jul 20.

Department of Paediatrics, Medical University of Vienna, Children's Cancer Research Institute (CCRI), St. Anna Kinderkrebsforschung, Vienna, Austria.

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October 2018

Clofarabine, high-dose cytarabine and liposomal daunorubicin in pediatric relapsed/refractory acute myeloid leukemia: a phase IB study.

Authors:

Natasha K A van Eijkelenburg Mareike Rasche Essam Ghazaly Michael N Dworzak Thomas Klingebiel Claudia Rossig Guy Leverger Jan Stary Eveline S J M De Bont Dana A Chitu Yves Bertrand Benoit Brethon Brigitte Strahm Inge M van der Sluis Gertjan J L Kaspers Dirk Reinhardt C Michel Zwaan

Haematologica 2018 09 17;103(9):1484-1492. Epub 2018 May 17.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands

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September 2018

How I treat myelodysplastic syndromes of childhood.

Authors:

Franco Locatelli Brigitte Strahm

Blood 2018 03 8;131(13):1406-1414. Epub 2018 Feb 8.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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March 2018

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

Nat Commun 2017 12 19;8(1):2126. Epub 2017 Dec 19.

Cancer Epigenetics Group, Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), INF 280, 69120, Heidelberg, Germany.

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December 2017

Constitutional mutations cause familial myelodysplastic syndrome and transient monosomy 7.

Haematologica 2018 03 7;103(3):427-437. Epub 2017 Dec 7.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Germany

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March 2018

Outcome of relapse after allogeneic HSCT in children with ALL enrolled in the ALL-SCT 2003/2007 trial.

Br J Haematol 2018 01 28;180(1):82-89. Epub 2017 Nov 28.

St. Anna Children's Hospital, Vienna, Austria.

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January 2018

Corrigendum: Clinical and Molecular Heterogeneity of RTEL1 Deficiency.

Front Immunol 2017 2;8:1250. Epub 2017 Oct 2.

Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Centre, University of Freiburg, Freiburg, Germany.

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October 2017

Clinical and Molecular Heterogeneity of RTEL1 Deficiency.

Front Immunol 2017 1;8:449. Epub 2017 May 1.

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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May 2017

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.

J Clin Invest 2017 May 27;127(5):1700-1713. Epub 2017 Mar 27.

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May 2017

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Authors:

Tim Ripperger Stefan S Bielack Arndt Borkhardt Ines B Brecht Birgit Burkhardt Gabriele Calaminus Klaus-Michael Debatin Hedwig Deubzer Uta Dirksen Cornelia Eckert Angelika Eggert Miriam Erlacher Gudrun Fleischhack Michael C Frühwald Astrid Gnekow Gudrun Goehring Norbert Graf Helmut Hanenberg Julia Hauer Barbara Hero Simone Hettmer Katja von Hoff Martin Horstmann Juliane Hoyer Thomas Illig Peter Kaatsch Roland Kappler Kornelius Kerl Thomas Klingebiel Udo Kontny Uwe Kordes Dieter Körholz Ewa Koscielniak Christof M Kramm Michaela Kuhlen Andreas E Kulozik Britta Lamottke Ivo Leuschner Dietmar R Lohmann Andrea Meinhardt Markus Metzler Lüder H Meyer Olga Moser Michaela Nathrath Charlotte M Niemeyer Rainer Nustede Kristian W Pajtler Claudia Paret Mareike Rasche Dirk Reinhardt Olaf Rieß Alexandra Russo Stefan Rutkowski Brigitte Schlegelberger Dominik Schneider Reinhard Schneppenheim Martin Schrappe Christopher Schroeder Dietrich von Schweinitz Thorsten Simon Monika Sparber-Sauer Claudia Spix Martin Stanulla Doris Steinemann Brigitte Strahm Petra Temming Kathrin Thomay Andre O von Bueren Peter Vorwerk Olaf Witt Marcin Wlodarski Willy Wössmann Martin Zenker Stefanie Zimmermann Stefan M Pfister Christian P Kratz

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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April 2017

A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis.

J Allergy Clin Immunol 2017 Apr 19;139(4):1302-1310.e4. Epub 2016 Sep 19.

Department of Pediatric Hematology and Oncology, Center for Pediatrics, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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April 2017

Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience.

Blood 2016 07 23;128(3):440-8. Epub 2016 May 23.

Department of Paediatric Immunology, Great North Children´s Hospital, Newcastle Upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.

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July 2016

Risk assessment of relapse by lineage-specific monitoring of chimerism in children undergoing allogeneic stem cell transplantation for acute lymphoblastic leukemia.

Haematologica 2016 06 11;101(6):741-6. Epub 2016 Feb 11.

Children's Cancer Research Institute, Vienna, Austria Department of Pediatrics, Medical University Vienna, Austria

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June 2016

Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency.

Authors:

Christian Klemann Ulrich Pannicke Deborah J Morris-Rosendahl Katerina Vlantis Marta Rizzi Holm Uhlig Thomas Vraetz Carsten Speckmann Brigitte Strahm Manolis Pasparakis Klaus Schwarz Stephan Ehl Jan C Rohr

Clin Immunol 2016 Mar 23;164:52-6. Epub 2016 Jan 23.

Center of Chronic Immunodeficiency, University Medical Center Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Germany. Electronic address:

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March 2016

Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG-MDS study group.

Authors:

Annamaria M Cseh Charlotte M Niemeyer Ayami Yoshimi Albert Catala Michael C Frühwald Henrik Hasle Mary M van den Heuvel-Eibrink Melchior Lauten Barbara De Moerloose Owen P Smith Toralf Bernig Bernd Gruhn Andreas E Kulozik Markus Metzler Lale Olcay Meinolf Suttorp Ingrid Furlan Brigitte Strahm Christian Flotho

Br J Haematol 2016 Mar 13;172(6):930-6. Epub 2016 Jan 13.

Division of Paediatric Haematology-Oncology, Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany.

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March 2016

Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents.

Blood 2016 Mar 23;127(11):1387-97; quiz 1518. Epub 2015 Dec 23.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium, Freiburg, Germany, and German Cancer Research Center, Heidelberg, Germany;

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March 2016

Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients.

Authors:

Marcus Weitz Brigitte Strahm Joerg J Meerpohl Maria Schmidt Dirk Bassler

Cochrane Database Syst Rev 2015 Dec 15(12):CD009898. Epub 2015 Dec 15.

Pediatric Nephrology, University Children's Hospital, Steinwiesstrasse 75, Zurich, Switzerland, 8032.

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December 2015

Extracorporeal photopheresis versus standard treatment for acute graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients.

Authors:

Marcus Weitz Brigitte Strahm Joerg J Meerpohl Maria Schmidt Dirk Bassler

Cochrane Database Syst Rev 2015 Dec 15(12):CD009759. Epub 2015 Dec 15.

Pediatric Nephrology, University Children's Hospital, Steinwiesstrasse 75, Zurich, Switzerland, 8032.

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December 2015

Second allogeneic stem cell transplant for aplastic anaemia: a retrospective study by the Severe Aplastic Anaemia Working Party of the European Society for Blood and Marrow Transplantation.

Authors:

Simone Cesaro Regis Peffault de Latour Gloria Tridello Marta Pillon Kristina Carlson Franca Fagioli Jean-Pierre Jouet Mickey B C Koh Irene Sara Panizzolo Slawomira Kyrcz-Krzemien Johan Maertens Alessandro Rambaldi Brigitte Strahm Didier Blaise Alexei Maschan Judith Marsh Carlo Dufour

Br J Haematol 2015 Nov 25;171(4):606-14. Epub 2015 Aug 25.

Paediatric Haematology, Institute G. Gaslini, Genova, Italy.

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November 2015

Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency.

Authors:

Sebastian Fuchs Anne Rensing-Ehl Ulrich Pannicke Myriam R Lorenz Paul Fisch Yogesh Jeelall Jan Rohr Carsten Speckmann Thomas Vraetz Susan Farmand Annette Schmitt-Graeff Marcus Krüger Brigitte Strahm Philipp Henneke Anselm Enders Keisuke Horikawa Christopher Goodnow Klaus Schwarz Stephan Ehl

Blood 2015 Oct 19;126(14):1658-69. Epub 2015 Aug 19.

Center for Chronic Immunodeficiency (CCI), University Medical Center and University of Freiburg, Freiburg, Germany; Center of Pediatric and Adolescent Medicine, University Medical Center and University of Freiburg, Freiburg, Germany;

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October 2015

Missing Cells: Pathophysiology, Diagnosis, and Management of (Pan)Cytopenia in Childhood.

Authors:

Miriam Erlacher Brigitte Strahm

Front Pediatr 2015 13;3:64. Epub 2015 Jul 13.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center of Freiburg , Freiburg , Germany.

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July 2015

Unmistakable Morphology? Infantile Malignant Osteopetrosis Resembling Juvenile Myelomonocytic Leukemia in Infants.

Authors:

Anne Strauss Ingrid Furlan Sandra Steinmann Bernd Buchholz Bernhard Kremens Claudia Rossig Selim Corbacioglu Revathi Rajagopal Georgia Lahr Ayami Yoshimi Brigitte Strahm Charlotte M Niemeyer Ansgar Schulz

J Pediatr 2015 Aug 15;167(2):486-8. Epub 2015 May 15.

Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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August 2015

Bridging to transplant with azacitidine in juvenile myelomonocytic leukemia: a retrospective analysis of the EWOG-MDS study group.

Authors:

Annamaria Cseh Charlotte M Niemeyer Ayami Yoshimi Michael Dworzak Henrik Hasle Marry M van den Heuvel-Eibrink Franco Locatelli Riccardo Masetti Markus Schmugge Ute Groß-Wieltsch Andrea Candás Andreas E Kulozik Lale Olcay Meinolf Suttorp Ingrid Furlan Brigitte Strahm Christian Flotho

Blood 2015 Apr;125(14):2311-3

Division of Pediatric Hematology-Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center, Freiburg, Germany German Cancer Consortium (DKTK), Heidelberg, Germany.

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April 2015

Stem-cell transplantation in children with acute lymphoblastic leukemia: A prospective international multicenter trial comparing sibling donors with matched unrelated donors-The ALL-SCT-BFM-2003 trial.

J Clin Oncol 2015 Apr 9;33(11):1265-74. Epub 2015 Mar 9.

Christina Peters, Susanne Matthes-Martin, and Ulrike Poetschger, St Anna Children's Hospital, Vienna, Austria; Martin Schrappe, University Medical Center Schleswig-Holstein and Christian-Albrechts-University Kiel; André Schrauder, Kinderarztpraxis am Aalborgring, Kiel; Arend von Stackelberg and Wolfram Ebell, Charité-Children's Hospital Berlin, Berlin; Peter Bader and Thomas Klingebiel, Johann Wolfgang Goethe University, Frankfurt; Peter Lang, University Hospital Tübingen, Tübingen; Karl-Walter Sykora and Martin Zimmerman, Hannover Medical School, Hannover; Johanna Schrum, University Medical Center Hamburg-Eppendorf, Hamburg; Bernhard Kremens, University Hospital Essen, Essen; Karoline Ehlert, University Clinic Greifswald, Greifswald; Michael H. Albert, Dr. von Hauner University Children's Hospital, München; Roland Meisel, University Hospital Düsseldorf, Düsseldorf; Wolfgang Holter, Children's University Hospital Erlangen, Erlangen; Brigitte Strahm, University Hospital Freiburg, Freiburg; Bernd Gruhn, University Hospital Jena, Jena; Ansgar Schulz, University Hospital Ulm, Ulm; Wilhelm Woessmann, University Clinic Giessen, Giessen, Germany; and Tayfun Gungor, University Children's Hospital Zürich, Zürich, Switzerland.

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April 2015

Monitoring of hematopoietic chimerism after transplantation for pediatric myelodysplastic syndrome: real-time or conventional short tandem repeat PCR in peripheral blood or bone marrow?

Authors:

Andre M Willasch Hermann Kreyenberg Nona Shayegi Eva Rettinger Vida Meyer Marion Zabel Peter Lang Bernhard Kremens Roland Meisel Brigitte Strahm Claudia Rossig Bernd Gruhn Thomas Klingebiel Charlotte M Niemeyer Peter Bader

Biol Blood Marrow Transplant 2014 Dec 31;20(12):1918-25. Epub 2014 Jul 31.

Division for Stem Cell Transplantation and Immunology, Department for Children and Adolescents, University Hospital, Goethe University, Frankfurt/Main, Germany.

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December 2014

Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients.

Authors:

Marcus Weitz Brigitte Strahm Joerg J Meerpohl Dirk Bassler

Cochrane Database Syst Rev 2014 Feb 25(2):CD009898. Epub 2014 Feb 25.

Department of Pediatrics, University of Tuebingen, Hoppe-Seyler-Strasse 1, Tübingen, Germany, 72076.

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February 2014

Extracorporeal photopheresis versus standard treatment for acute graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients.

Authors:

Marcus Weitz Brigitte Strahm Joerg J Meerpohl Dirk Bassler

Cochrane Database Syst Rev 2014 Feb 25(2):CD009759. Epub 2014 Feb 25.

Pediatric Nephrology, University Children's Hospital, Steinwiesstrasse 75, Zurich, Switzerland, 8032.

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February 2014

Hematopoietic stem cell transplantation in children and young adults with secondary myelodysplastic syndrome and acute myelogenous leukemia after aplastic anemia.

Authors:

Ayami Yoshimi Brigitte Strahm Irith Baumann Ingrid Furlan Stephan Schwarz Andrea Teigler-Schlegel Joachim-Ulrich Walther Brigitte Schlegelberger Gudrun Göhring Peter Nöllke Monika Führer Charlotte M Niemeyer

Biol Blood Marrow Transplant 2014 Mar 5;20(3):425-9. Epub 2013 Dec 5.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany.

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March 2014

Comparison of horse and rabbit antithymocyte globulin in immunosuppressive therapy for refractory cytopenia of childhood.

Haematologica 2014 Apr 25;99(4):656-63. Epub 2013 Oct 25.

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April 2014

Analysis of risk factors influencing outcomes after cord blood transplantation in children with juvenile myelomonocytic leukemia: a EUROCORD, EBMT, EWOG-MDS, CIBMTR study.

Blood 2013 Sep 7;122(12):2135-41. Epub 2013 Aug 7.

Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Bambino Gesù, Università di Pavia, Rome, Italy;

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September 2013

Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation: priorities of the Westhafen Intercontinental Group.

Biol Blood Marrow Transplant 2013 Sep 21;19(9):1279-87. Epub 2013 Jul 21.

Pediatric Hematology/Oncology/BMT, British Columbia Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada.

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September 2013

Next-generation-sequencing-spectratyping reveals public T-cell receptor repertoires in pediatric very severe aplastic anemia and identifies a β chain CDR3 sequence associated with hepatitis-induced pathogenesis.

Authors:

Pina F I Krell Susanne Reuther Ute Fischer Thomas Keller Stephan Weber Michael Gombert Friedhelm R Schuster Corinna Asang Polina Stepensky Brigitte Strahm Roland Meisel Jens Stoye Arndt Borkhardt

Haematologica 2013 Sep 28;98(9):1388-96. Epub 2013 May 28.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children’s Hospital, Medical Faculty, Heinrich Heine University, Duesseldorf, Germany.

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September 2013

Comparison of the efficacy of rabbit and horse antithymocyte globulin for the treatment of severe aplastic anemia in children.

Authors:

Ayami Yoshimi Charlotte M Niemeyer Monika M Führer Brigitte Strahm

Blood 2013 Jan;121(5):860-1

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January 2013

High incidence of Fanconi anaemia in patients with a morphological picture consistent with refractory cytopenia of childhood.

Authors:

Ayami Yoshimi Charlotte Niemeyer Irith Baumann Stephan Schwarz-Furlan Detlev Schindler Wolfram Ebell Brigitte Strahm

Br J Haematol 2013 Jan 9;160(1):109-11. Epub 2012 Oct 9.

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January 2013

Prolonged KI polyomavirus infection in immunodeficient child.

Authors:

Valeria Falcone Marcus Panning Brigitte Strahm Thomas Vraetz Sibylle Bierbaum Dieter Neumann-Haefelin Daniela Huzly

Emerg Infect Dis 2012 Apr;18(4):706-8

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April 2012

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML.

Blood 2012 Mar 11;119(11):e96-9. Epub 2012 Jan 11.

Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany.

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March 2012

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency.

J Immunol 2012 Feb 21;188(3):1523-33. Epub 2011 Dec 21.

Centre of Chronic Immunodeficiency, University of Freiburg, Freiburg 79106, Germany.

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February 2012

Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation.

Authors:

Eva Rettinger Andre M Willasch Hermann Kreyenberg Arndt Borkhardt Wolfgang Holter Bernhard Kremens Brigitte Strahm Wilhelm Woessmann Christine Mauz-Koerholz Bernd Gruhn Stefan Burdach Michael H Albert Paul-Gerhardt Schlegel Thomas Klingebiel Peter Bader

Blood 2011 Nov 26;118(20):5681-8. Epub 2011 Sep 26.

Department of Pediatric Hematology, Oncology and Hemostaseology, Goethe-University, University Children's Hospital, Theodor-Stern-Kai 7, Frankfurt/Main, Germany.

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November 2011

Deletion of human GP1BB and SEPT5 is associated with Bernard-Soulier syndrome, platelet secretion defect, polymicrogyria, and developmental delay.

Authors:

Ingrid Bartsch Kirstin Sandrock Francois Lanza Paquita Nurden Ina Hainmann Anna Pavlova Andreas Greinacher Uta Tacke Michael Barth Anja Busse Johannes Oldenburg Martin Bommer Brigitte Strahm Andrea Superti-Furga Barbara Zieger

Thromb Haemost 2011 Sep 28;106(3):475-83. Epub 2011 Jul 28.

Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Mathildenstr 1, 79106 Freiburg, Germany.

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September 2011

NOD2/CARD15 gene polymorphisms affect outcome in pediatric allogeneic stem cell transplantation.

Blood 2011 Jul;118(4):1181-4

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July 2011

Long term survival in children with acute leukaemia and complications requiring mechanical ventilation.

Authors:

Daniel Steinbach Bernhard Wilhelm Hans-Rudolf Kiermaier Ursula Creutzig Martin Schrappe Martin Zimmermann Klaus-Michael Debatin Bernd Gruhn Arend von Stackelberg Heribert Jürgens Brigitte Strahm Dirk Reinhardt Anja Möricke

Arch Dis Child 2011 Nov 29;96(11):1026-32. Epub 2011 Jun 29.

Children's Hospital, University Children's Hospital Ulm, Eythstrasse 24, 89075 Ulm, Germany.

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November 2011

Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome.

Blood 2011 May 15;117(18):4871-80. Epub 2011 Mar 15.

Department of Pediatrics and Adolescent Medicine, University Medical Center, Freiburg, Germany.

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May 2011

X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease.

Blood 2011 Jan 6;117(1):53-62. Epub 2010 Oct 6.

Center of Immunodeficiency, Molecular Immunology Unit, Institute of Child Health, London, United Kingdom.

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January 2011

Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases.

Haematologica 2010 Dec 7;95(12):2080-7. Epub 2010 Sep 7.

Centre of Pediatrics and Adolescent Medicine, University Medical Centre, Freiburg, Germany.

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December 2010

Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome.

Blood 2010 Nov 27;116(19):3766-9. Epub 2010 Aug 27.

Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.

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November 2010

Persistence of human bocavirus DNA in immunocompromised children.

Authors:

Thomas Schenk Barbara Maier Markus Hufnagel Brigitte Strahm Udo Kontny Dieter Neumann-Haefelin Valeria Falcone

Pediatr Infect Dis J 2011 Jan;30(1):82-4

Department of Virology, Freiburg University Medical Center, Freiburg, Germany.

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January 2011

Therapeutic strategy in p47-phox deficient chronic granulomatous disease presenting as inflammatory bowel disease.

Authors:

Folke Freudenberg Uwe Wintergerst Angela Roesen-Wolff Michael H Albert Christine Prell Brigitte Strahm Sibylle Koletzko Stephan Ehl Dirk Roos Alberto Tommasini Alessandro Ventura Bernd H Belohradsky Reinhard Seger Joachim Roesler Tayfun Güngör

J Allergy Clin Immunol 2010 Apr;125(4):943-946.e1

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April 2010

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis.

Authors:

Dirk Bassler Matthias Briel Victor M Montori Melanie Lane Paul Glasziou Qi Zhou Diane Heels-Ansdell Stephen D Walter Gordon H Guyatt David N Flynn Mohamed B Elamin Mohammad Hassan Murad Nisrin O Abu Elnour Julianna F Lampropulos Amit Sood Rebecca J Mullan Patricia J Erwin Clare R Bankhead Rafael Perera Carolina Ruiz Culebro John J You Sohail M Mulla Jagdeep Kaur Kara A Nerenberg Holger Schünemann Deborah J Cook Kristina Lutz Christine M Ribic Noah Vale German Malaga Elie A Akl Ignacio Ferreira-Gonzalez Pablo Alonso-Coello Gerard Urrutia Regina Kunz Heiner C Bucher Alain J Nordmann Heike Raatz Suzana Alves da Silva Fabio Tuche Brigitte Strahm Benjamin Djulbegovic Neill K J Adhikari Edward J Mills Femida Gwadry-Sridhar Haresh Kirpalani Heloisa P Soares Paul J Karanicolas Karen E A Burns Per Olav Vandvik Fernando Coto-Yglesias Pedro Paulo M Chrispim Tim Ramsay

JAMA 2010 Mar;303(12):1180-7

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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March 2010

Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2).

Authors:

Matthias Briel Melanie Lane Victor M Montori Dirk Bassler Paul Glasziou German Malaga Elie A Akl Ignacio Ferreira-Gonzalez Pablo Alonso-Coello Gerard Urrutia Regina Kunz Carolina Ruiz Culebro Suzana Alves da Silva David N Flynn Mohamed B Elamin Brigitte Strahm M Hassan Murad Benjamin Djulbegovic Neill K J Adhikari Edward J Mills Femida Gwadry-Sridhar Haresh Kirpalani Heloisa P Soares Nisrin O Abu Elnour John J You Paul J Karanicolas Heiner C Bucher Julianna F Lampropulos Alain J Nordmann Karen E A Burns Sohail M Mulla Heike Raatz Amit Sood Jagdeep Kaur Clare R Bankhead Rebecca J Mullan Kara A Nerenberg Per Olav Vandvik Fernando Coto-Yglesias Holger Schünemann Fabio Tuche Pedro Paulo M Chrispim Deborah J Cook Kristina Lutz Christine M Ribic Noah Vale Patricia J Erwin Rafael Perera Qi Zhou Diane Heels-Ansdell Tim Ramsay Stephen D Walter Gordon H Guyatt

Trials 2009 Jul 6;10:49. Epub 2009 Jul 6.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada.

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July 2009

Disseminated bocavirus infection after stem cell transplant.

Authors:

Thomas Schenk Brigitte Strahm Udo Kontny Markus Hufnagel Dieter Neumann-Haefelin Valeria Falcone

Emerg Infect Dis 2007 Sep;13(9):1425-7

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September 2007

Extramedullary relapse of therapy-related myelodysplastic syndrome after donor leukocyte infusion.

Authors:

Mwe Mwe Chao Udo Kontny Ingo Brink Gudrun Göhring Annette Schmitt-Gräff Manfred Rister Brigitte Strahm

Ann Hematol 2008 Feb 6;87(2):165-6. Epub 2007 Sep 6.

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February 2008

The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma.

Authors:

Brigitte Strahm Adam D Durbin Elizabeth Sexsmith David Malkin

Clin Exp Metastasis 2008 1;25(1):1-10. Epub 2007 Sep 1.

Division of Haematology and Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, Canada, M5G 1X8.

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June 2008

Toxicity and outcome of children with treatment related acute myeloid leukemia.

Authors:

Uri Tabori Giselle Revach Paul C Nathan Brigitte Strahm Alisa Rachlis Mary Shago Ronald Grant John Doyle David Malkin

Pediatr Blood Cancer 2008 Jan;50(1):17-23

Departments of Hematology Oncology and Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Canada.

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January 2008

Defibrotide for the treatment of hepatic veno-occlusive disease in children.

Authors:

Sean R Bulley Brigitte Strahm John Doyle L Lee Dupuis

Pediatr Blood Cancer 2007 Jun;48(7):700-4

Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

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June 2007

Hereditary cancer predisposition in children: genetic basis and clinical implications.

Authors:

Brigitte Strahm David Malkin

Int J Cancer 2006 Nov;119(9):2001-6

Division of Haematology and Oncology, Department of Paediatrics, The Hospital for Sick Children Research Institute, University of Toronto, Toronto, Ont, Canada.

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November 2006