Publications by authors named "Brigitte Schlegelberger"

100Publications

Risk of tumor lysis syndrome in patients with acute myeloid leukemia treated with venetoclax-containing regimens without dose ramp-up.

Ann Hematol 2020 Jul 23. Epub 2020 Jul 23.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Carl-Neuberg Straße 1, 30625, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-020-04181-5DOI Listing
July 2020

Wnt status-dependent oncogenic role of BCL9 and BCL9L in hepatocellular carcinoma.

Hepatol Int 2020 May 22;14(3):373-384. Epub 2019 Aug 22.

Department of Human Genetics, Hannover Medical School, Carl-Neuberg-Straße 1, Hannover, 30625, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12072-019-09977-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220899PMC
May 2020

Imatinib dose reduction in major molecular response of chronic myeloid leukemia: results from the German Chronic Myeloid Leukemia-Study IV.

Haematologica 2019 05 4;104(5):955-962. Epub 2018 Dec 4.

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität München, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2018.206797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518910PMC
May 2019

Octasomy 21 in a patient with secondary AML after CMML: the role of acquired NRAS mutations in triggering aneuploidy.

Leuk Lymphoma 2018 10 31;59(10):2478-2481. Epub 2018 Jan 31.

a Department of Human Genetics , Hannover Medical School , Hannover , Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2018.1427861DOI Listing
October 2018

Mutational Spectrum of Fanconi Anemia Associated Myeloid Neoplasms.

Klin Padiatr 2017 Nov 13;229(6):329-334. Epub 2017 Nov 13.

Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0043-117046DOI Listing
November 2017

RUNX1 deficiency (familial platelet disorder with predisposition to myeloid leukemia, FPDMM).

Semin Hematol 2017 04 13;54(2):75-80. Epub 2017 Apr 13.

Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, IDIM-CONICET, Buenos Aires, Argentina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.seminhematol.2017.04.006DOI Listing
April 2017

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.38142DOI Listing
April 2017

A common ancestral DNMT3A-mutated preleukemic clone giving rise to AML and MDS in an adolescent girl.

Leuk Lymphoma 2017 03 28;58(3):718-721. Epub 2016 Nov 28.

e Division of Pediatric Hematology and Oncology, Department of Pediatrics , University Medical Center Freiburg , Freiburg , Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2016.1207765DOI Listing
March 2017

HDAC inhibition activates the apoptosome via Apaf1 upregulation in hepatocellular carcinoma.

Eur J Med Res 2016 Jun 24;21(1):26. Epub 2016 Jun 24.

Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40001-016-0217-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919854PMC
June 2016

Clinical utility gene card for: Familial platelet disorder with associated myeloid malignancies.

Eur J Hum Genet 2016 08 27;24(8). Epub 2016 Jan 27.

Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2015.278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970691PMC
August 2016

Acute lymphoblastic leukemia and lymphoma in the context of constitutional mismatch repair deficiency syndrome.

Eur J Med Genet 2016 Mar 30;59(3):133-42. Epub 2015 Dec 30.

Institute of Human Genetics, Hannover Medical School, Hannover, Germany.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S17697212153005
Publisher Site
http://dx.doi.org/10.1016/j.ejmg.2015.12.014DOI Listing
March 2016

The stem cell zinc finger 1 (SZF1)/ZNF589 protein has a human-specific evolutionary nucleotide DNA change and acts as a regulator of cell viability in the hematopoietic system.

Exp Hematol 2016 Apr 29;44(4):257-68. Epub 2015 Dec 29.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2015.12.005DOI Listing
April 2016

The heteromeric transcription factor GABP activates the ITGAM/CD11b promoter and induces myeloid differentiation.

Biochim Biophys Acta 2015 Sep 11;1849(9):1145-54. Epub 2015 Jul 11.

Institute of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2015.07.005DOI Listing
September 2015

A child with Li-Fraumeni syndrome: Modes to inactivate the second allele of TP53 in three different malignancies.

Pediatr Blood Cancer 2015 Aug 18;62(8):1481-4. Epub 2015 Mar 18.

Department of Pediatric Hematology and Oncology, University Hospital Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.25486DOI Listing
August 2015

Comprehensive MALDI-TOF biotyping of the non-redundant Harvard Pseudomonas aeruginosa PA14 transposon insertion mutant library.

PLoS One 2015 9;10(2):e0117144. Epub 2015 Feb 9.

Department of Molecular Bacteriology, Helmholtz Center for Infection Research, Braunschweig, Germany; Institute of Molecular Bacteriology, Twincore, Center for Experimental and Clinical Infection Research, A joint venture of the Helmholtz Center for Infection Research Braunschweig and the MHH, Hannover, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117144PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321832PMC
January 2016

Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis.

J Mol Med (Berl) 2015 Jan 18;93(1):39-49. Epub 2014 Nov 18.

Department of Tumorigenesis and Cell Differentiation, Max Delbrueck Center for Molecular Medicine, Robert-Roessle-Str.10, 13125, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-014-1215-5DOI Listing
January 2015

Equivalence of BCR-ABL transcript levels with complete cytogenetic remission in patients with chronic myeloid leukemia in chronic phase.

J Cancer Res Clin Oncol 2014 Nov 22;140(11):1965-9. Epub 2014 Jun 22.

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-014-1746-8DOI Listing
November 2014

TET2 mutations in cytogenetically normal acute myeloid leukemia: clinical implications and evolutionary patterns.

Genes Chromosomes Cancer 2014 Oct 5;53(10):824-32. Epub 2014 Jun 5.

INSERM U985, Institut Gustave Roussy, Villejuif, France; Department of Hematology, Oncology, and Tumor Immunology, Charité, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22191DOI Listing
October 2014

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Cancer Cell 2014 Jun 15;25(6):794-808. Epub 2014 May 15.

Haematopoietic Stem Cell Biology Laboratory, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Departments of Cell and Molecular Biology, Medicine Huddinge, and Laboratory Medicine, Huddinge, Karolinska Institutet and Center for Hematology and Regenerative Medicine, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2014.03.036DOI Listing
June 2014

Lack of noncanonical RAS mutations in cytogenetically normal acute myeloid leukemia.

Ann Hematol 2014 Jun 16;93(6):977-82. Epub 2014 Apr 16.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-014-2061-9DOI Listing
June 2014

Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia.

Cancers (Basel) 2013 Jul 4;5(3):857-74. Epub 2013 Jul 4.

Institute of Cell and Molecular Pathology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6694/5/3/857
Publisher Site
http://dx.doi.org/10.3390/cancers5030857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795368PMC
July 2013

Genetic instability of modified stem cells - a first step towards malignant transformation?

Am J Stem Cells 2013 8;2(1):39-51. Epub 2013 Mar 8.

Institute of Cell and Molecular Pathology, Hannover Medical School Hannover, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636728PMC
May 2013