Publications by authors named "Brigitte M Frey"

54Publications

Corrigendum to "Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: Tracing the complexity of human postnatal steroidogenesis" [J. Steroid Biochem. Mol. Biol. 154 (2015) 226-236].

J Steroid Biochem Mol Biol 2018 Oct 16;183:238. Epub 2018 Aug 16.

Department of Pediatrics (Pediatric Endocrinology and Diabetology, University Children's Hospital) and Department of Clinical Research, University of Bern, Freiburgstrasse 15, 3010, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2018.08.005DOI Listing
October 2018

Androgen biosynthesis during minipuberty favors the backdoor pathway over the classic pathway: Insights into enzyme activities and steroid fluxes in healthy infants during the first year of life from the urinary steroid metabolome.

J Steroid Biochem Mol Biol 2017 01 25;165(Pt B):312-322. Epub 2016 Jul 25.

Department of Pediatrics (Pediatric Endocrinology and Diabetology, University Children's Hospital) and Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15/C845, 3010 Bern, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2016.07.009DOI Listing
January 2017

Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: Tracing the complexity of human postnatal steroidogenesis.

J Steroid Biochem Mol Biol 2015 Nov 19;154:226-36. Epub 2015 Aug 19.

Department of Pediatrics (Pediatric Endocrinology and Diabetology, University Children's Hospital) and Department of Clinical Research, University of Bern, Freiburgstrasse 15, 3010, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2015.07.024DOI Listing
November 2015

Detection and functional portrayal of a novel class of dihydrotestosterone derived selective progesterone receptor modulators (SPRM).

J Steroid Biochem Mol Biol 2015 Mar 23;147:111-23. Epub 2014 Dec 23.

Department of Nephrology and Hypertension and Clinical Pharmacology, University of Berne, Berne, Switzerland; Department of Clinical Research, University of Berne, Berne, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09600760140031
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http://dx.doi.org/10.1016/j.jsbmb.2014.12.009DOI Listing
March 2015

18F-RB390: innovative ligand for imaging the T877A androgen receptor mutant in prostate cancer via positron emission tomography (PET).

Prostate 2015 Mar 30;75(4):348-59. Epub 2014 Oct 30.

Department of Nephrology & Hypertension and Clinical Pharmacology, University of Berne, Berne, Switzerland.

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http://doi.wiley.com/10.1002/pros.22919
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http://dx.doi.org/10.1002/pros.22919DOI Listing
March 2015

Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11β-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines.

PLoS One 2014 18;9(8):e105354. Epub 2014 Aug 18.

Department of Nephrology & Hypertension and Clinical Pharmacology and Department of Clinical Research, University Hospital of Berne, Berne, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105354PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136812PMC
December 2015

Regulation of 11β-hydroxysteroid dehydrogenase type 2 by microRNA.

Hypertension 2014 Oct 30;64(4):860-6. Epub 2014 Jun 30.

From the Department of Nephrology, Hypertension, and Clinical Pharmacology (M.R., T.A., D.M., F.J.F., B.V., B.M.F.) and Department of Biology and Bioinformatics (S.N., R.B.), University of Bern, Bern, Switzerland; Vital-IT, Swiss Institute of Bioinformatics, University of Lausanne, Lausanne, Switzerland (S.N.); and Department of Clinical Research, University Hospital Bern, Bern, Switzerland (B.M.F.)

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.00002DOI Listing
October 2014

Evidence for glucocorticoid-mediated hypertension after uninephrectomy.

Physiol Rep 2013 Oct 11;1(5):e00101. Epub 2013 Oct 11.

Department of Nephrology, Hypertension and Clinical Pharmacology, University Hospital Berne Berne, Switzerland.

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http://dx.doi.org/10.1002/phy2.101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841037PMC
October 2013

Major cardiac surgery induces an increase in sex steroids in prepubertal children.

Steroids 2014 Mar 16;81:57-63. Epub 2013 Nov 16.

Dept. of Nephrology & Hypertension, University Hospital Bern, Bern, Switzerland; Dept. of Clinical Research, University Hospital Bern, Bern, Switzerland.

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http://dx.doi.org/10.1016/j.steroids.2013.11.003DOI Listing
March 2014

Vascular endothelial growth factor-A and aldosterone: relevance to normal pregnancy and preeclampsia.

Hypertension 2013 May 4;61(5):1111-7. Epub 2013 Mar 4.

Department of Nephrology, Hypertension and Clinical Pharmacology, University Hospital Bern, Berne, Switzerland.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00575DOI Listing
May 2013

A novel steroidal antiandrogen targeting wild type and mutant androgen receptors.

Biochem Pharmacol 2011 Dec 1;82(11):1651-62. Epub 2011 Sep 1.

Department of Nephrology & Hypertension, University of Berne, Berne, Switzerland.

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http://dx.doi.org/10.1016/j.bcp.2011.08.020DOI Listing
December 2011

Sodium thiosulfate pharmacokinetics in hemodialysis patients and healthy volunteers.

Clin J Am Soc Nephrol 2011 Jun 12;6(6):1447-55. Epub 2011 May 12.

Department of Nephrology and Hypertension, Inselspital, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.2215/CJN.10241110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109943PMC
June 2011

Effect of electroporation-mediated diphtheria toxin A expression on PSA positive human prostate xenograft tumors in SCID mice.

Prostate 2011 Jun 4;71(8):872-80. Epub 2010 Nov 4.

Department of Nephrology and Hypertension, University of Berne, Berne, Switzerland.

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http://doi.wiley.com/10.1002/pros.21303
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http://dx.doi.org/10.1002/pros.21303DOI Listing
June 2011

Epigenetic regulation of somatic angiotensin-converting enzyme by DNA methylation and histone acetylation.

Epigenetics 2011 Apr 1;6(4):478-89. Epub 2011 Apr 1.

UMR M100 IFREMER-UCBN, Physiologie et Ecophysiologie des Mollusques Marins, Esplanade de la Paix, Université de Caen Basse-Normandie, Caen, France.

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http://dx.doi.org/10.4161/epi.6.4.14961DOI Listing
April 2011

Regulation of placental growth by aldosterone and cortisol.

Endocrinology 2011 Jan 10;152(1):263-71. Epub 2010 Nov 10.

Department of Nephrology/Hypertension, University Hospital Bern, 3010 Berne, Switzerland.

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http://dx.doi.org/10.1210/en.2010-0525DOI Listing
January 2011

Urinary proteomics before and after extracorporeal circulation in patients with and without acute kidney injury.

J Thorac Cardiovasc Surg 2010 Mar;139(3):692-700

Department of Nephrology/Hypertension, Inselspital, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1016/j.jtcvs.2009.11.015DOI Listing
March 2010

'Pergularain e I'--a plant cysteine protease with thrombin-like activity from Pergularia extensa latex.

Thromb Res 2010 Mar 24;125(3):e100-5. Epub 2009 Oct 24.

Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysore 570 006, India.

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http://dx.doi.org/10.1016/j.thromres.2009.10.002DOI Listing
March 2010

Glycyrrhetinic acid food supplementation lowers serum potassium concentration in chronic hemodialysis patients.

Kidney Int 2009 Oct 29;76(8):877-84. Epub 2009 Jul 29.

Department of Nephrology and Hypertension, Inselspital, University of Berne, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S008525381554066
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http://dx.doi.org/10.1038/ki.2009.269DOI Listing
October 2009

Role of DNA methylation in the tissue-specific expression of the CYP17A1 gene for steroidogenesis in rodents.

J Endocrinol 2009 Jul 29;202(1):99-109. Epub 2009 Apr 29.

Pediatric Endocrinology and Diabetology, University Children's Hospital Bern, Bern, Switzerland.

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http://dx.doi.org/10.1677/JOE-08-0353DOI Listing
July 2009

Tumor necrosis factor-alpha upregulates 11beta-hydroxysteroid dehydrogenase type 1 expression by CCAAT/enhancer binding protein-beta in HepG2 cells.

Am J Physiol Endocrinol Metab 2009 Feb 16;296(2):E367-77. Epub 2008 Dec 16.

Depts. of Nephrology and Hypertension and Clinical Research, Freiburgstrasse 15, Univ. Hospital, Berne, CH-3010 Berne, Switzerland.

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http://dx.doi.org/10.1152/ajpendo.90531.2008DOI Listing
February 2009

Prematurity is related to high placental cortisol in preeclampsia.

Pediatr Res 2009 Feb;65(2):198-202

Department of Nephrology and Hypertension, University of Bern, 3010 Berne, Switzerland.

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http://dx.doi.org/10.1203/PDR.0b013e31818d6c24DOI Listing
February 2009

Sodium thiosulfate prevents vascular calcifications in uremic rats.

Kidney Int 2008 Dec 24;74(11):1444-53. Epub 2008 Sep 24.

Department of Nephrology and Hypertension, Inselspital, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1038/ki.2008.455DOI Listing
December 2008

Age-dependent decrease in 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) activity in hypertensive patients.

Am J Hypertens 2008 Jun 3;21(6):644-9. Epub 2008 Apr 3.

Department of Geriatrics, Inselspital University Hospital, Berne, Switzerland.

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http://dx.doi.org/10.1038/ajh.2008.152DOI Listing
June 2008

Analbuminemic Nagase rats: blood pressure response to dietary salt challenge.

Nephron Physiol 2006 19;104(2):p81-6. Epub 2006 Jun 19.

Clinic and Policlinic of Nephrology and Hypertension, University Hospital Inselspital, Berne, Switzerland.

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https://www.karger.com/Article/FullText/94002
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http://dx.doi.org/10.1159/000094002DOI Listing
October 2006

Extracellular ATP determines 11beta-hydroxysteroid dehydrogenase type 2 activity via purinergic receptors.

J Am Soc Nephrol 2005 Dec 26;16(12):3507-16. Epub 2005 Oct 26.

Department of Nephrology/Hypertension, University Hospital Berne, Berne, Switzerland.

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http://dx.doi.org/10.1681/ASN.2005010108DOI Listing
December 2005

Inhibition of secretory phospholipase A(2) enzyme by bilirubin: a new role as endogenous anti-inflammatory molecule.

Mol Cell Biochem 2005 Aug;276(1-2):219-25

Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysore 570 006, India.

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http://dx.doi.org/10.1007/s11010-005-4441-xDOI Listing
August 2005

Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin.

FASEB J 2005 Oct 4;19(12):1689-91. Epub 2005 Aug 4.

Department of Nephrology and Hypertension, University of Bern, Bern, Switzerland.

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http://www.fasebj.org/doi/10.1096/fj.04-3647fje
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http://dx.doi.org/10.1096/fj.04-3647fjeDOI Listing
October 2005

Regulation of epithelial sodium channel in puromycin aminonucleoside-induced unilateral experimental nephrotic syndrome in normal and analbuminemic Nagase rats.

Nephron Physiol 2005 12;101(3):p51-62. Epub 2005 Jul 12.

Division of Nephrology and Hypertension, University Hospital Inselspital, Berne, Switzerland.

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http://dx.doi.org/10.1159/000086716DOI Listing
May 2006

Sodium retention in rats with liver cirrhosis is associated with increased renal abundance of NaCl cotransporter (NCC).

Nephrol Dial Transplant 2005 Sep 14;20(9):1833-41. Epub 2005 Jun 14.

Division of Nephrology and Hypertension, University Hospital Inselspital, University of Berne, Freiburgstrasse 15, 3010, Berne, Switzerland.

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http://dx.doi.org/10.1093/ndt/gfh916DOI Listing
September 2005

Use of Pavo cristatus feather extract for the better management of snakebites: neutralization of inflammatory reactions.

J Ethnopharmacol 2005 Jun 11;99(2):229-37. Epub 2005 Apr 11.

Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysore 570006, Karnataka, India.

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http://dx.doi.org/10.1016/j.jep.2005.02.027DOI Listing
June 2005

Tumor necrosis factor alpha and phorbol 12-myristate-13-acetate down-regulate human 11beta-hydroxysteroid dehydrogenase type 2 through p50/p50 NF-kappaB homodimers and Egr-1.

FASEB J 2005 Apr 19;19(6):650-2. Epub 2005 Jan 19.

Department of Nephrology and Hypertension, University Hospital, Bern, Switzerland.

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http://dx.doi.org/10.1096/fj.04-2820fjeDOI Listing
April 2005

CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity.

J Clin Endocrinol Metab 2005 Feb 26;90(2):1220-5. Epub 2004 Oct 26.

Division of Nephrology, Zoological Institute, University of Berne, Berne 3010, Switzerland.

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http://dx.doi.org/10.1210/jc.2004-1031DOI Listing
February 2005

Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression.

J Clin Invest 2004 Oct;114(8):1146-57

Department of Nephrology and Hypertension, University Hospital of Berne, Berne UNK 3010, Switzerland.

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http://dx.doi.org/10.1172/JCI21647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC522246PMC
October 2004

Low prevalence of nonconservative mutations of serum and glucocorticoid-regulated kinase (SGK1) gene in hypertensive and renal patients.

Nephrol Dial Transplant 2004 Oct 10;19(10):2499-504. Epub 2004 Aug 10.

Division of Nephrology and Hypertension, University Hospital, Berne, Switzerland.

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http://dx.doi.org/10.1093/ndt/gfh417DOI Listing
October 2004

Glucocorticoid-mediated mineralocorticoid receptor activation and hypertension.

Curr Opin Nephrol Hypertens 2004 Jul;13(4):451-8

Department of Nephrology and Hypertension, Inselspital, University of Berne, Switzerland.

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http://dx.doi.org/10.1097/01.mnh.0000133976.32559.b0DOI Listing
July 2004

The 11-ketosteroid 11-ketodexamethasone is a glucocorticoid receptor agonist.

Mol Cell Endocrinol 2004 Feb;214(1-2):27-37

Department of Clinical Research, University of Berne, Freiburgstrasse 15, 3010 Berne, Switzerland.

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http://dx.doi.org/10.1016/j.mce.2003.11.027DOI Listing
February 2004

A rapid screening assay for inhibitors of 11beta-hydroxysteroid dehydrogenases (11beta-HSD): flavanone selectively inhibits 11beta-HSD1 reductase activity.

Mol Cell Endocrinol 2003 Dec;212(1-2):41-9

Department of Clinical Research, Division of Nephrology and Hypertension, University of Berne, Freiburgstrasse 15, Berne 3010, Switzerland.

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http://dx.doi.org/10.1016/j.mce.2003.09.027DOI Listing
December 2003

Angiotensin II regulates 11beta-hydroxysteroid dehydrogenase type 2 via AT2 receptors.

Kidney Int 2003 Sep;64(3):970-7

Division of Nephrology/Hypertension, University of Berne, Berne, Switzerland.

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http://dx.doi.org/10.1046/j.1523-1755.2003.00192.xDOI Listing
September 2003

Hypoxia causes down-regulation of 11 beta-hydroxysteroid dehydrogenase type 2 by induction of Egr-1.

FASEB J 2003 May 5;17(8):917-9. Epub 2003 Mar 5.

Division of Nephrology and Hypertension, University of Berne, 3010 Berne, Switzerland.

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http://dx.doi.org/10.1096/fj.02-0582fjeDOI Listing
May 2003

Gene delivery by a steroid-peptide nucleic acid conjugate.

FASEB J 2002 Sep 1;16(11):1426-8. Epub 2002 Jul 1.

Division of Nephrology and Hypertension and Clinical Research, University of Berne, CH-3010 Berne-Inselspital, Switzerland.

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http://dx.doi.org/10.1096/fj.01-0706fjeDOI Listing
September 2002

Salt-sensitivity of blood pressure and decreased 11beta-hydroxysteroid dehydrogenase type 2 activity after renal transplantation.

Transplantation 2002 Jul;74(1):66-72

Division of Nephrology and Hypertension and Institute of Physiology, University of Fribourg, Switzerland.

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http://dx.doi.org/10.1097/00007890-200207150-00012DOI Listing
July 2002

Reduced 11beta-hydroxysteroid dehydrogenase activity in experimental nephrotic syndrome.

Nephrol Dial Transplant 2002 May;17(5):753-8

Division of Nephrology and Hypertension, University Hospital of Berne, Inselspital, Berne, Switzerland.

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http://dx.doi.org/10.1093/ndt/17.5.753DOI Listing
May 2002

Role of the alpha-adducin genotype on renal disease progression.

Kidney Int 2002 Apr;61(4):1270-5

Division of Nephrology and Hypertension, Inselspital, University of Berne, Berne, Switzerland.

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http://dx.doi.org/10.1046/j.1523-1755.2002.00275.xDOI Listing
April 2002

In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3.

J Biol Chem 2002 Apr 15;277(17):14647-56. Epub 2002 Feb 15.

Division of Nephrology and Hypertension, Department of Internal Medicine, University Hospital of Berne, CH-3010 Berne, Switzerland.

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http://dx.doi.org/10.1074/jbc.M111549200DOI Listing
April 2002

Glycyrrhetinic acid decreases plasma potassium concentrations in patients with anuria.

J Am Soc Nephrol 2002 Jan;13(1):191-6

University Hospital of Berne, Berne, Switzerland.

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January 2002

Fluid Shear Stress Reduces 11ss-Hydroxysteroid Dehydrogenase Type 2.

Hypertension 2001 Jan;37(1):160-169

Division of Nephrology/Hypertension, University of Berne, Berne, Switzerland.

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http://dx.doi.org/10.1161/01.hyp.37.1.160DOI Listing
January 2001