Publications by authors named "Brien P Riley"

61Publications

A large-scale genome-wide association study meta-analysis of cannabis use disorder.

Authors:
Emma C Johnson Ditte Demontis Thorgeir E Thorgeirsson Raymond K Walters Renato Polimanti Alexander S Hatoum Sandra Sanchez-Roige Sarah E Paul Frank R Wendt Toni-Kim Clarke Dongbing Lai Gunnar W Reginsson Hang Zhou June He David A A Baranger Daniel F Gudbjartsson Robbee Wedow Daniel E Adkins Amy E Adkins Jeffry Alexander Silviu-Alin Bacanu Tim B Bigdeli Joseph Boden Sandra A Brown Kathleen K Bucholz Jonas Bybjerg-Grauholm Robin P Corley Louisa Degenhardt Danielle M Dick Benjamin W Domingue Louis Fox Alison M Goate Scott D Gordon Laura M Hack Dana B Hancock Sarah M Hartz Ian B Hickie David M Hougaard Kenneth Krauter Penelope A Lind Jeanette N McClintick Matthew B McQueen Jacquelyn L Meyers Grant W Montgomery Ole Mors Preben B Mortensen Merete Nordentoft John F Pearson Roseann E Peterson Maureen D Reynolds John P Rice Valgerdur Runarsdottir Nancy L Saccone Richard Sherva Judy L Silberg Ralph E Tarter Thorarinn Tyrfingsson Tamara L Wall Bradley T Webb Thomas Werge Leah Wetherill Margaret J Wright Stephanie Zellers Mark J Adams Laura J Bierut Jason D Boardman William E Copeland Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Richard A Grucza Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William G Iacono Eric O Johnson Kenneth S Kendler Martin A Kennedy Henry R Kranzler Pamela A F Madden Hermine H Maes Brion S Maher Nicholas G Martin Matthew McGue Andrew M McIntosh Sarah E Medland Elliot C Nelson Bernice Porjesz Brien P Riley Michael C Stallings Michael M Vanyukov Scott Vrieze Lea K Davis Ryan Bogdan Joel Gelernter Howard J Edenberg Kari Stefansson Anders D Børglum Arpana Agrawal

Lancet Psychiatry 2020 Dec 20;7(12):1032-1045. Epub 2020 Oct 20.

Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2215-0366(20)30339-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674631PMC
December 2020

Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence.

Alcohol Clin Exp Res 2020 Oct 17. Epub 2020 Oct 17.

Virginia Institute for Psychiatric and Behavioral Genetics, (GOM, ESV, CC, MM, KSK, BPR, MFM, S-AB, VIV), Virginia Commonwealth University, Richmond, Virginia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acer.14479DOI Listing
October 2020

TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders.

Am J Med Genet B Neuropsychiatr Genet 2020 Dec 21;183(8):454-463. Epub 2020 Sep 21.

Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.32823DOI Listing
December 2020

mTADA is a framework for identifying risk genes from de novo mutations in multiple traits.

Nat Commun 2020 06 10;11(1):2929. Epub 2020 Jun 10.

Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-020-16487-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287090PMC
June 2020

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.

Authors:
Melissa A Munn-Chernoff Emma C Johnson Yi-Ling Chou Jonathan R I Coleman Laura M Thornton Raymond K Walters Zeynep Yilmaz Jessica H Baker Christopher Hübel Scott Gordon Sarah E Medland Hunna J Watson Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Jakob Grove Anjali K Henders Janne T Larsen Richard Parker Liselotte V Petersen Jennifer Jordan Martin A Kennedy Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Preben Bo Mortensen Renato Polimanti Jeanette N McClintick Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Franziska Degenhardt Anna R Docherty Alexis C Edwards Jerome C Foo Louis Fox Josef Frank Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Colin Hodgkinson Per Hoffmann Jouke-Jan Hottenga Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen Roseann E Peterson Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Hang Zhou Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Mark A Frye Wolfgang Gäebel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer Gabriele Koller John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie H Witt Norbert Wodarz Peter Zill Daniel E Adkins Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz E Jane Costello Harriet de Wit Nancy Diazgranados Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Victor Hesselbrock John K Hewitt Christian J Hopfer William G Iacono Eric O Johnson Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik K E Magnusson Elliot C Nelson Markus M Nöthen Abraham A Palmer Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard J Rose Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Tracey D Wade Andrew C Heath Grant W Montgomery Nicholas G Martin Patrick F Sullivan Jaakko Kaprio Gerome Breen Joel Gelernter Howard J Edenberg Cynthia M Bulik Arpana Agrawal

Addict Biol 2020 Feb 16:e12880. Epub 2020 Feb 16.

Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/adb.12880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429266PMC
February 2020

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2019 04 23;180(3):223-231. Epub 2019 Feb 23.

Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition & Genomics (NICOG) Centre & NCBES Galway Neuroscience Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.32716DOI Listing
April 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Polygenic prediction of the phenome, across ancestry, in emerging adulthood.

Psychol Med 2018 08 27;48(11):1814-1823. Epub 2017 Nov 27.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0033291717003312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971142PMC
August 2018

Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students.

Front Genet 2017 15;8:30. Epub 2017 Mar 15.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth UniversityRichmond, VA, USA; Department of Psychiatry, Virginia Commonwealth UniversityRichmond, VA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2017.00030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350109PMC
March 2017

The Genetic Architecture of Major Depressive Disorder in Han Chinese Women.

JAMA Psychiatry 2017 02;74(2):162-168

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamapsychiatry.2016.3578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319866PMC
February 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence.

PLoS One 2015 18;10(9):e0137671. Epub 2015 Sep 18.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, United States of America; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, United States of America; Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond, VA, United States of America; Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137671PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575063PMC
May 2016

Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes.

Schizophr Bull 2016 Mar 27;42(2):279-87. Epub 2015 Aug 27.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, VA; Mental Health Service Line, Washington VA Medical Center, Washington, DC; Department of Psychiatry, Georgetown University School of Medicine, Washington, DC.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/schbul/sbv119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753595PMC
March 2016

DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts.

Bioinformatics 2015 Oct 9;31(19):3099-104. Epub 2015 Jun 9.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btv348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576696PMC
October 2015

Genome-wide gene pathway analysis of psychotic illness symptom dimensions based on a new schizophrenia-specific model of the OPCRIT.

Schizophr Res 2015 May 13;164(1-3):181-6. Epub 2015 Mar 13.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth, University School of Medicine, VA, USA; Washington Veterans Affairs Healthcare System, Washington D.C. USA; Georgetown University School of Medicine, Washington D.C. USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09209964150011
Publisher Site
http://dx.doi.org/10.1016/j.schres.2015.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409533PMC
May 2015

SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans.

Proc Natl Acad Sci U S A 2015 Mar 23;112(10):3032-7. Epub 2015 Feb 23.

Departments of Pharmacology and Toxicology, Virginia Commonwealth University-Alcohol Research Center, Virginia Commonwealth University, Richmond, VA 23298

View Article

Download full-text PDF

Source
http://www.pnas.org/lookup/doi/10.1073/pnas.1413451112
Publisher Site
http://dx.doi.org/10.1073/pnas.1413451112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364201PMC
March 2015

JEPEG: a summary statistics based tool for gene-level joint testing of functional variants.

Bioinformatics 2015 Apr 12;31(8):1176-82. Epub 2014 Dec 12.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Center for Biomarker Research & Personalized Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/bioinformatics/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btu816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393522PMC
April 2015

No evidence that runs of homozygosity are associated with schizophrenia in an Irish genome-wide association dataset.

Schizophr Res 2014 Apr 20;154(1-3):79-82. Epub 2014 Feb 20.

Department of Psychiatry & Neuropsychiatric Genetics Research Group, School of Medicine, The Trinity Centre for Health Sciences, St. James's Hospital, Dublin 8, Ireland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.schres.2014.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034753PMC
April 2014

DIST: direct imputation of summary statistics for unmeasured SNPs.

Bioinformatics 2013 Nov 28;29(22):2925-7. Epub 2013 Aug 28.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btt500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810851PMC
November 2013

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

Authors:
Stephan Ripke Colm O'Dushlaine Kimberly Chambert Jennifer L Moran Anna K Kähler Susanne Akterin Sarah E Bergen Ann L Collins James J Crowley Menachem Fromer Yunjung Kim Sang Hong Lee Patrik K E Magnusson Nick Sanchez Eli A Stahl Stephanie Williams Naomi R Wray Kai Xia Francesco Bettella Anders D Borglum Brendan K Bulik-Sullivan Paul Cormican Nick Craddock Christiaan de Leeuw Naser Durmishi Michael Gill Vera Golimbet Marian L Hamshere Peter Holmans David M Hougaard Kenneth S Kendler Kuang Lin Derek W Morris Ole Mors Preben B Mortensen Benjamin M Neale Francis A O'Neill Michael J Owen Milica Pejovic Milovancevic Danielle Posthuma John Powell Alexander L Richards Brien P Riley Douglas Ruderfer Dan Rujescu Engilbert Sigurdsson Teimuraz Silagadze August B Smit Hreinn Stefansson Stacy Steinberg Jaana Suvisaari Sarah Tosato Matthijs Verhage James T Walters Douglas F Levinson Pablo V Gejman Kenneth S Kendler Claudine Laurent Bryan J Mowry Michael C O'Donovan Michael J Owen Ann E Pulver Brien P Riley Sibylle G Schwab Dieter B Wildenauer Frank Dudbridge Peter Holmans Jianxin Shi Margot Albus Madeline Alexander Dominique Campion David Cohen Dimitris Dikeos Jubao Duan Peter Eichhammer Stephanie Godard Mark Hansen F Bernard Lerer Kung-Yee Liang Wolfgang Maier Jacques Mallet Deborah A Nertney Gerald Nestadt Nadine Norton Francis A O'Neill George N Papadimitriou Robert Ribble Alan R Sanders Jeremy M Silverman Dermot Walsh Nigel M Williams Brandon Wormley Maria J Arranz Steven Bakker Stephan Bender Elvira Bramon David Collier Benedicto Crespo-Facorro Jeremy Hall Conrad Iyegbe Assen Jablensky Rene S Kahn Luba Kalaydjieva Stephen Lawrie Cathryn M Lewis Kuang Lin Don H Linszen Ignacio Mata Andrew McIntosh Robin M Murray Roel A Ophoff John Powell Dan Rujescu Jim Van Os Muriel Walshe Matthias Weisbrod Durk Wiersma Peter Donnelly Ines Barroso Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden P Corvin Panos Deloukas Audrey Duncanson Janusz Jankowski Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas W Wood Chris C A Spencer Gavin Band Céline Bellenguez Colin Freeman Garrett Hellenthal Eleni Giannoulatou Matti Pirinen Richard D Pearson Amy Strange Zhan Su Damjan Vukcevic Peter Donnelly Cordelia Langford Sarah E Hunt Sarah Edkins Rhian Gwilliam Hannah Blackburn Suzannah J Bumpstead Serge Dronov Matthew Gillman Emma Gray Naomi Hammond Alagurevathi Jayakumar Owen T McCann Jennifer Liddle Simon C Potter Radhi Ravindrarajah Michelle Ricketts Avazeh Tashakkori-Ghanbaria Matthew J Waller Paul Weston Sara Widaa Pamela Whittaker Ines Barroso Panos Deloukas Christopher G Mathew Jenefer M Blackwell Matthew A Brown Aiden P Corvin Mark I McCarthy Chris C A Spencer Elvira Bramon Aiden P Corvin Michael C O'Donovan Kari Stefansson Edward Scolnick Shaun Purcell Steven A McCarroll Pamela Sklar Christina M Hultman Patrick F Sullivan

Nat Genet 2013 Oct 25;45(10):1150-9. Epub 2013 Aug 25.

1] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827979PMC
October 2013

Molecular validation of the schizophrenia spectrum.

Schizophr Bull 2014 Jan 22;40(1):60-5. Epub 2013 Aug 22.

*To whom correspondence should be addressed; Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics of VCU, Box 980126, Richmond, VA 23298-0126, US; tel: (804)-828-8590, fax: (804)-828-1471, e-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/schbul/sbt122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885304PMC
January 2014

Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.

J Stud Alcohol Drugs 2011 Sep;72(5):752-62

Department of Public Health and Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 100, Taiwan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174022PMC
http://dx.doi.org/10.15288/jsad.2011.72.752DOI Listing
September 2011

Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).

Alcohol Clin Exp Res 2011 Feb 17;35(2):376-85. Epub 2010 Nov 17.

Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1530-0277.2010.01353.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443636PMC
February 2011

MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Schizophr Res 2010 Dec 2;124(1-3):183-91. Epub 2010 Aug 2.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA 23298-0424, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.schres.2010.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373420PMC
December 2010

Schizophrenia gene networks and pathways and their applications for novel candidate gene selection.

PLoS One 2010 Jun 29;5(6):e11351. Epub 2010 Jun 29.

Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011351PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894047PMC
June 2010

Allelic heterogeneity in genetic association meta-analysis: an application to DTNBP1 and schizophrenia.

Hum Hered 2010 4;69(2):71-9. Epub 2009 Dec 4.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298-0126, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000264445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077085PMC
February 2010

No association of dysbindin with symptom factors of schizophrenia in an Irish case-control sample.

Am J Med Genet B Neuropsychiatr Genet 2010 Mar;153B(2):700-705

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.31029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859300PMC
March 2010

Psychiatric genetics gets a boost.

Nat Genet 2008 Sep;40(9):1042-4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng0908-1042DOI Listing
September 2008

Unraveling the molecular mechanisms of alcohol dependence.

Trends Genet 2009 Jan 17;25(1):49-55. Epub 2008 Nov 17.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, PO Box 980424, Virginia Commonwealth University, Richmond, VA 23298-0424, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016895250800287
Publisher Site
http://dx.doi.org/10.1016/j.tig.2008.10.005DOI Listing
January 2009

The trace amine associated receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sample.

Schizophr Res 2009 Feb 30;107(2-3):249-54. Epub 2008 Oct 30.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 800 East Leigh Street, Biotech 1-110, Richmond VA 23298, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.schres.2008.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673704PMC
February 2009

Commentary on 'The case for gene-environment interactions in psychiatry'.

Authors:
Brien P Riley

Curr Opin Psychiatry 2008 Jul;21(4):324-5

Department of Psychiatry, Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.yco.0000320757.22733.30DOI Listing
July 2008

Genetic and Environmental Influences on Symptom Domains in Twins and Siblings with Autism.

Res Autism Spectr Disord 2008 Apr;2(2):320-331

Drs. Mazefsky, Riley, and Maes were in the Virginia Institute for Psychiatric and Behavioral Genetics at Virginia Commonwealth University at the time of the study. Dr. Mazefsky is now in the Departments of Pediatrics and Psychiatry at the University of Pittsburgh. Dr. Goin-Kochel is in the Department of Molecular and Human Genetics at Baylor College of Medicine. Send reprint requests to Carla Mazefsky, 3705 5th Ave, Child Development Unit, Children's Hospital of Pittsburgh, Pittsburgh, PA 15213; 412-692-6520;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rasd.2007.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734093PMC
April 2008

Candidate genes for schizophrenia: a survey of association studies and gene ranking.

Am J Med Genet B Neuropsychiatr Genet 2008 Oct;147B(7):1173-81

Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.30743DOI Listing
October 2008

Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.

Alcohol Clin Exp Res 2008 May 4;32(5):785-95. Epub 2008 Mar 4.

Institute of Clinical Medicine, College of Medicine, National Cheng Kung University Hospital 138, National Cheng Kung University, Sheng-Li Road, Tainan 704, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1530-0277.2008.00642.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665790PMC
May 2008

Level of functioning in autism spectrum disorders: phenotypic congruence among affected siblings.

J Autism Dev Disord 2008 Jul 30;38(6):1019-27. Epub 2007 Oct 30.

Molecular and Human Genetics, Baylor College of Medicine, Texas Children's Hospital, 6621 Fannin Street, CC1560, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10803-007-0476-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104536PMC
July 2008

A genome-wide linkage analysis for the personality trait neuroticism in the Irish affected sib-pair study of alcohol dependence.

Am J Med Genet B Neuropsychiatr Genet 2007 Jun;144B(4):463-8

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia 23298-0126, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.30478DOI Listing
June 2007

A genome-wide scan for modifier loci in schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2007 Jul;144B(5):589-95

Washington VA Medical Center, Washington, DC 20422, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.30442DOI Listing
July 2007

Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence.

Alcohol Clin Exp Res 2006 Nov;30(11):1807-16

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1530-0277.2006.00217.x
Publisher Site
http://dx.doi.org/10.1111/j.1530-0277.2006.00217.xDOI Listing
November 2006

Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia.

Am J Psychiatry 2005 Oct;162(10):1824-32

Washington VA Medical Center-Georgetown University Medical Center Schizophrenia Research Program, 50 Irving St. NW, Washington, DC 20422, USA.

View Article

Download full-text PDF

Source
http://psychiatryonline.org/doi/abs/10.1176/appi.ajp.162.10.
Publisher Site
http://dx.doi.org/10.1176/appi.ajp.162.10.1824DOI Listing
October 2005