Brian S Appleby

Brian S Appleby

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Brian S Appleby

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Clinical Laboratory Tests Used To Aid in Diagnosis of Human Prion Disease.

J Clin Microbiol 2019 Oct 24;57(10). Epub 2019 Sep 24.

National Prion Disease Pathology Surveillance Center, Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA

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http://dx.doi.org/10.1128/JCM.00769-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760952PMC
October 2019

Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species.

MBio 2019 Jul 23;10(4). Epub 2019 Jul 23.

National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1128/mBio.01091-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650550PMC
July 2019

Human prion diseases.

Curr Opin Infect Dis 2019 Jun;32(3):272-276

Department of Neurology, University Hospitals Cleveland Medical Center.

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http://dx.doi.org/10.1097/QCO.0000000000000552DOI Listing
June 2019

Feasibility of Remote Assessment of Human Prion Diseases for Research and Surveillance.

Dement Geriatr Cogn Disord 2019 12;47(1-2):79-90. Epub 2019 Mar 12.

Neurology Center Inc., Lorain, Ohio, USA.

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http://dx.doi.org/10.1159/000497055DOI Listing
March 2019

Therapeutic strategies for prion disease: a practical perspective.

Curr Opin Pharmacol 2019 02 30;44:15-19. Epub 2018 Nov 30.

Department of Neurology, University Hospitals Cleveland Medical Center, 3619 Park East Drive, Suite 206, Beachwood, OH 44122, USA.

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http://dx.doi.org/10.1016/j.coph.2018.11.006DOI Listing
February 2019

Variably protease-sensitive prionopathy.

Handb Clin Neurol 2018 ;153:175-190

Department of Pathology, Case Western Reserve University, Cleveland, OH, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/B97804446394550
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http://dx.doi.org/10.1016/B978-0-444-63945-5.00010-6DOI Listing
September 2018

Fatal familial insomnia and sporadic fatal insomnia.

Handb Clin Neurol 2018 ;153:271-299

Department of Pathology, Case Western Reserve University, Cleveland, OH, United States. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-63945-5.00015-5DOI Listing
September 2018

Symptomatic treatment, care, and support of CJD patients.

Handb Clin Neurol 2018 ;153:399-408

CJD Foundation, Akron, OH, United States.

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http://dx.doi.org/10.1016/B978-0-444-63945-5.00021-0DOI Listing
September 2018

A Practical Primer on Prion Pathology.

J Neuropathol Exp Neurol 2018 05;77(5):346-352

National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1093/jnen/nly019DOI Listing
May 2018

Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Correlation of Histopathology and MRI in Prion Disease.

Alzheimer Dis Assoc Disord 2017 Jan-Mar;31(1):1-7

Departments of *Neurology ‡Diagnostic Radiology ¶Quantitative Health Sciences, Cleveland Clinic Departments of †Radiology §Pathology **Neurology, University Hospitals Case Medical Center ∥National Prion Disease Pathology Surveillance Center #Department of Neuroradiology, Humanitas Research Hospital IRCCS, Milano, Italy.

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http://dx.doi.org/10.1097/WAD.0000000000000188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322151PMC
November 2017

Comprehensive and Methodical: Diagnostic and Management Approaches to Rapidly Progressive Dementia.

Curr Treat Options Neurol 2017 Sep 30;19(11):40. Epub 2017 Sep 30.

Department of Neurology, University Hospitals Cleveland Medical Center, 3619 Park East Drive, Suite 206, Beachwood, OH, 44122, USA.

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http://dx.doi.org/10.1007/s11940-017-0474-1DOI Listing
September 2017

Many challenges of conducting clinical trials in CJD.

Authors:
Brian S Appleby

J Neurol Neurosurg Psychiatry 2017 02 4;88(2):98. Epub 2016 Nov 4.

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http://dx.doi.org/10.1136/jnnp-2016-314578DOI Listing
February 2017

Autoimmune-mediated cognitive impairment: a case report.

Psychosomatics 2014 Nov-Dec;55(6):698-702. Epub 2014 Jan 1.

Division of Geriatrics and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University of Medicine, Baltimore, MD.

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https://linkinghub.elsevier.com/retrieve/pii/S00333182130024
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http://dx.doi.org/10.1016/j.psym.2013.12.012DOI Listing
October 2016

Visual art therapy in sporadic Creutzfeldt-Jakob disease: a case study.

Neurocase 2016 18;22(2):243-7. Epub 2016 Jan 18.

a Departments of Neurology and Psychiatry , Case Western Reserve University School of Medicine and University Hospitals , Cleveland , OH , USA.

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http://dx.doi.org/10.1080/13554794.2015.1135963DOI Listing
October 2016

A young-onset frontal dementia with dramatic calcifications due to a novel CSF1R mutation.

Neurocase 2016 06 19;22(3):257-62. Epub 2016 Apr 19.

a Department of Neurology , Case Western Reserve University Hospitals , Beachwood , OH , USA.

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http://dx.doi.org/10.1080/13554794.2016.1175635DOI Listing
June 2016

Caregiver burden in atypical dementias: comparing frontotemporal dementia, Creutzfeldt-Jakob disease, and Alzheimer's disease.

Int Psychogeriatr 2016 Feb 5;28(2):269-73. Epub 2015 Oct 5.

Departments of Neurology, Psychiatry, and Pathology,Case Western Reserve University School of Medicine,Cleveland,OH,USA.

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http://dx.doi.org/10.1017/S1041610215001647DOI Listing
February 2016

Unusual Case of Sporadic Creutzfeldt-Jakob Disease Subtype VV1.

J Neuropsychiatry Clin Neurosci 2015 ;27(2):e172-3

Brain Health and Memory Center, University Hospitals Case Medical Center, Beachwood, OH.

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http://dx.doi.org/10.1176/appi.neuropsych.14070160DOI Listing
January 2016

Severe hyponatremia and seizures secondary to psychogenic polydipsia in a case of frontotemporal dementia.

J Neuropsychiatry Clin Neurosci 2014 ;26(4):E19-20

Dept. of Neurology, Case Western Reserve University School of Medicine, Cleveland, OH (BSA); and Dept. of Neurology, Cleveland Clinic Foundation, Cleveland, OH.

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http://dx.doi.org/10.1176/appi.neuropsych.13100237DOI Listing
December 2015

Subclavian steal syndrome presenting as a reversible dementia.

J Neuropsychiatry Clin Neurosci 2015 ;27(1):e74-5

Depts. of Neurology and Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH (BSA); and Dept. of Vascular Surgery, Cleveland Clinic Foundation, Cleveland, OH (RK).

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http://dx.doi.org/10.1176/appi.neuropsych.13110353DOI Listing
November 2015

Initial diagnoses of patients ultimately diagnosed with prion disease.

J Alzheimers Dis 2014 ;42(3):833-9

Veterans Affairs Healthcare System, Department of Neurology, Washington, DC, USA Department of Neurology, Georgetown University Hospital, Washington, DC, USA.

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http://dx.doi.org/10.3233/JAD-132465DOI Listing
August 2015

Rapidly progressive young-onset dementias: neuropsychiatric aspects.

Psychiatr Clin North Am 2015 Jun 2;38(2):221-32. Epub 2015 Mar 2.

Department of Neurology, Case Western Reserve University School of Medicine & University Hospitals, 3619 Park East Drive, Suite 211, Beachwood, OH 44122, USA; Department of Psychiatry, Case Western Reserve University School of Medicine & University Hospitals, 3619 Park East Drive, Suite 211, Beachwood, OH 44122, USA; Department of Pathology, Case Western Reserve University School of Medicine & University Hospitals, 3619 Park East Drive, Suite 211, Beachwood, OH 44122, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psc.2015.01.001DOI Listing
June 2015

Rapidly progressive Alzheimer's disease features distinct structures of amyloid-β.

Brain 2015 Apr 15;138(Pt 4):1009-22. Epub 2015 Feb 15.

1 Department of Pathology, Case Western Reserve University School of Medicine, 2085 Adelbert Rd, Cleveland, OH 44106, USA 2 National Prion Disease Pathology Surveillance Centre, Case Western Reserve University School of Medicine, 2085 Adelbert Rd, Cleveland, OH 44106, USA 3 Department of Neurology, Case Western Reserve University School of Medicine, 2085 Adelbert Rd, Cleveland, OH 44106, USA

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http://dx.doi.org/10.1093/brain/awv006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014074PMC
April 2015

Discovering new treatments for Alzheimer's disease by repurposing approved medications.

Curr Top Med Chem 2013 ;13(18):2306-27

Cleveland Clinic Lou Ruvo Center for Brain Health, 9500 Euclid Avenue/U10, Cleveland, OH 44195.

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http://dx.doi.org/10.2174/15680266113136660162DOI Listing
April 2014

A review: treatment of Alzheimer's disease discovered in repurposed agents.

Dement Geriatr Cogn Disord 2013 9;35(1-2):1-22. Epub 2013 Jan 9.

Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland, OH, USA.

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http://dx.doi.org/10.1159/000345791DOI Listing
August 2013

The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease.

Am J Geriatr Psychiatry 2013 Jul 6;21(7):685-95. Epub 2013 Feb 6.

Johns Hopkins University School of Medicine, Division of Geriatric Psychiatry and Neuropsychiatry, Baltimore, MD 21224, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10647481130001
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http://dx.doi.org/10.1016/j.jagp.2013.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428504PMC
July 2013

Racial and ethnic differences in individuals with sporadic Creutzfeldt-jakob disease in the United States of America.

PLoS One 2012 18;7(6):e38884. Epub 2012 Jun 18.

Lou Ruvo Center for Brain Health, Department of Psychiatry and Psychology, Neurological Institute, Cleveland Clinic Foundation, Cleveland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038884PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377728PMC
December 2012

D178N, 129Val and N171S, 129Val genotype in a family with Creutzfeldt-Jakob disease.

Dement Geriatr Cogn Disord 2010 12;30(5):424-31. Epub 2010 Nov 12.

Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, Md., USA.

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https://www.karger.com/Article/FullText/321472
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http://dx.doi.org/10.1159/000321472DOI Listing
April 2011

Rapidly progressive dementias and the treatment of human prion diseases.

Expert Opin Pharmacother 2011 Jan 23;12(1):1-12. Epub 2010 Nov 23.

Johns Hopkins University School of Medicine, Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Meyer 279, 600 N. Wolfe St., Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1517/14656566.2010.514903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304579PMC
January 2011

Estimating severity of illness and disability in Frontotemporal Dementia: Preliminary analysis of the Dementia Disability Rating (DDR).

Acta Neuropsychol 2011 ;9(2):141-153

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903383PMC
January 2011

Psychotropic medications and the treatment of human prion diseases.

Authors:
Brian S Appleby

CNS Neurol Disord Drug Targets 2009 Nov;8(5):353-62

Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Division of Geriatric Psychiatry and Neuropsychiatry, Baltimore, MD, USA.

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http://dx.doi.org/10.2174/187152709789541961DOI Listing
November 2009

Prion diseases: targets and treatments of symptoms and disease progression. Editorial.

Authors:
Brian S Appleby

CNS Neurol Disord Drug Targets 2009 Nov;8(5):315

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http://dx.doi.org/10.2174/187152709789542032DOI Listing
November 2009

Predictors of depression and anxiety in patients with intracranial neoplasms.

J Neuropsychiatry Clin Neurosci 2008 ;20(4):447-9

Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1176/jnp.2008.20.4.447DOI Listing
April 2009

Characteristics of established and proposed sporadic Creutzfeldt-Jakob disease variants.

Arch Neurol 2009 Feb;66(2):208-15

Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1001/archneurol.2008.533DOI Listing
February 2009

Trace and transference: therapy in a post-structuralist era.

Authors:
Brian S Appleby

Am J Psychother 2008 ;62(2):103-15

Johns Hopkins Hospital, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1176/appi.psychotherapy.2008.62.2.103DOI Listing
August 2008

Does the presentation of Creutzfeldt-Jakob disease vary by age or presumed etiology? A meta-analysis of the past 10 years.

J Neuropsychiatry Clin Neurosci 2007 ;19(4):428-35

The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1176/jnp.2007.19.4.428DOI Listing
January 2008

Psychiatric and neuropsychiatric adverse events associated with deep brain stimulation: A meta-analysis of ten years' experience.

Mov Disord 2007 Sep;22(12):1722-8

Department of Psychiatry, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1002/mds.21551DOI Listing
September 2007

Should we be teaching philosophy to psychiatrists-in-training?

Authors:
Brian S Appleby

Acad Psychiatry 2007 May-Jun;31(3):246-7

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http://dx.doi.org/10.1176/appi.ap.31.3.246DOI Listing
August 2007

Mania as a possible prodrome to dementia.

J Neuropsychiatry Clin Neurosci 2007 ;19(2):194

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http://dx.doi.org/10.1176/jnp.2007.19.2.194DOI Listing
June 2007