Brian M Wolpin

Brian M Wolpin

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Brian M Wolpin

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Influence of genetic variation in the vitamin D pathway on plasma 25-hydroxyvitamin D levels and survival among patients with metastatic colorectal cancer.

Cancer Causes Control 2019 Jul 18;30(7):757-765. Epub 2019 May 18.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Ave, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10552-019-01183-1DOI Listing
July 2019

Metabolic Alterations as a Signpost to Early Pancreatic Cancer.

Gastroenterology 2019 05 26;156(6):1560-1563. Epub 2019 Mar 26.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.03.028DOI Listing
May 2019

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.

Authors:
Naomi Walsh Han Zhang Paula L Hyland Qi Yang Evelina Mocci Mingfeng Zhang Erica J Childs Irene Collins Zhaoming Wang Alan A Arslan Laura Beane-Freeman Paige M Bracci Paul Brennan Federico Canzian Eric J Duell Steven Gallinger Graham G Giles Michael Goggins Gary E Goodman Phyllis J Goodman Rayjean J Hung Charles Kooperberg Robert C Kurtz Núria Malats Loic LeMarchand Rachel E Neale Sara H Olson Ghislaine Scelo Xiao O Shu Stephen K Van Den Eeden Kala Visvanathan Emily White Wei Zheng Demetrius Albanes Gabriella Andreotti Ana Babic William R Bamlet Sonja I Berndt Ayelet Borgida Marie-Christine Boutron-Ruault Lauren Brais Paul Brennan Bas Bueno-de-Mesquita Julie Buring Kari G Chaffee Stephen Chanock Sean Cleary Michelle Cotterchio Lenka Foretova Charles Fuchs J Michael M Gaziano Edward Giovannucci Michael Goggins Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Vladimir Janout Eric A Klein Robert C Kurtz Daniel Laheru I-Min Lee Lingeng Lu Núria Malats Satu Mannisto Roger L Milne Ann L Oberg Irene Orlow Alpa V Patel Ulrike Peters Miquel Porta Francisco X Real Nathaniel Rothman Howard D Sesso Gianluca Severi Debra Silverman Oliver Strobel Malin Sund Mark D Thornquist Geoffrey S Tobias Jean Wactawski-Wende Nick Wareham Elisabete Weiderpass Nicolas Wentzensen William Wheeler Herbert Yu Anne Zeleniuch-Jacquotte Peter Kraft Donghui Li Eric J Jacobs Gloria M Petersen Brian M Wolpin Harvey A Risch Laufey T Amundadottir Kai Yu Alison P Klein Rachael Z Stolzenberg-Solomon

J Natl Cancer Inst 2018 Dec 12. Epub 2018 Dec 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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https://academic.oup.com/jnci/advance-article/doi/10.1093/jn
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http://dx.doi.org/10.1093/jnci/djy155DOI Listing
December 2018

Prediagnosis Use of Statins Associates With Increased Survival Times of Patients With Pancreatic Cancer.

Clin Gastroenterol Hepatol 2018 Aug 21;16(8):1300-1306.e3. Epub 2018 Feb 21.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056316PMC
August 2018

Reply.

Gastroenterology 2018 Aug 9. Epub 2018 Aug 9.

Department of Medical Oncology, Dana-Farber Cancer Institute and, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1053/j.gastro.2018.08.013DOI Listing
August 2018

Re: Regular use of aspirin or non-aspirin nonsteroidal anti-inflammatory drugs is not associated with risk of incident pancreatic cancer in two large cohort studies.

Gastroenterology 2018 Aug 9. Epub 2018 Aug 9.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1053/j.gastro.2018.08.013DOI Listing
August 2018

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Authors:
Alison P Klein Brian M Wolpin Harvey A Risch Rachael Z Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J Childs Jason W Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A Arslan Ana Babic William R Bamlet Laura Beane-Freeman Sonja I Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G Chaffee Charles C Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J Michael M Gaziano Maria Gazouli Graham G Giles Edward Giovannucci Michael Goggins Gary E Goodman Phyllis J Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Eric J Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A Klein Manolis Kogevinas Charles Kooperberg Matthew H Kulke Juozas Kupcinskas Robert J Kurtz Daniel Laheru Stefano Landi Rita T Lawlor I-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L Milne Beatrice Mohelníková-Duchoňová Rachel E Neale John P Neoptolemos Ann L Oberg Sara H Olson Irene Orlow Claudio Pasquali Alpa V Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X Real Nathaniel Rothman Ghislaine Scelo Howard D Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D Thornquist Geoffrey S Tobias Stephen K Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M Petersen Laufey T Amundadottir

Nat Commun 2018 02 8;9(1):556. Epub 2018 Feb 8.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-02942-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805680PMC
February 2018

Cigarette Smoking and Pancreatic Cancer Survival.

J Clin Oncol 2017 Jun 30;35(16):1822-1828. Epub 2017 Mar 30.

Chen Yuan, Vicente Morales-Oyarvide, Ana Babic, Zhi Rong Qian, Douglas A. Rubinson, Kimmie Ng, Shuji Ogino, Charles S. Fuchs, and Brian M. Wolpin, Dana-Farber Cancer Institute and Harvard Medical School; Chen Yuan, Peter Kraft, Edward L. Giovannucci, Shuji Ogino, Meir J. Stampfer, Howard D. Sesso, and JoAnn E. Manson, Harvard School of Public Health; Ying Bao, Edward L. Giovannucci, Shuji Ogino, Meir J. Stampfer, John Michael Gaziano, Howard D. Sesso, JoAnn E. Manson, and Charles S. Fuchs, Brigham and Women's Hospital and Harvard Medical School; John Michael Gaziano, Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston; Clary B. Clish, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA; and Barbara B. Cochrane, University of Washington School of Nursing, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2016.71.2026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455596PMC
June 2017

Reply to A. Braillon.

J Clin Oncol 2017 04 17;35(10):1136-1137. Epub 2017 Jan 17.

Chen Yuan, Dana-Farber Cancer Institute, Boston, MA; and Brian M. Wolpin, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2016.70.9261DOI Listing
April 2017

When, What, and Why of Perioperative Treatment of Potentially Curable Pancreatic Adenocarcinoma.

J Clin Oncol 2017 Feb 28;35(5):485-489. Epub 2016 Dec 28.

Kimberly Perez, Thomas E. Clancy, Joseph D. Mancias, Michael H. Rosenthal, and Brian M. Wolpin, Brigham and Women's Hospital, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2016.70.2134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455317PMC
February 2017

Cumulative consumption of branched-chain amino acids and incidence of type 2 diabetes.

Int J Epidemiol 2016 10 13;45(5):1482-1492. Epub 2016 Jul 13.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA

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http://dx.doi.org/10.1093/ije/dyw143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100612PMC
October 2016

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21.

Authors:
Mingfeng Zhang Zhaoming Wang Ofure Obazee Jinping Jia Erica J Childs Jason Hoskins Gisella Figlioli Evelina Mocci Irene Collins Charles C Chung Christopher Hautman Alan A Arslan Laura Beane-Freeman Paige M Bracci Julie Buring Eric J Duell Steven Gallinger Graham G Giles Gary E Goodman Phyllis J Goodman Aruna Kamineni Laurence N Kolonel Matthew H Kulke Núria Malats Sara H Olson Howard D Sesso Kala Visvanathan Emily White Wei Zheng Christian C Abnet Demetrius Albanes Gabriella Andreotti Lauren Brais H Bas Bueno-de-Mesquita Daniela Basso Sonja I Berndt Marie-Christine Boutron-Ruault Maarten F Bijlsma Hermann Brenner Laurie Burdette Daniele Campa Neil E Caporaso Gabriele Capurso Giulia Martina Cavestro Michelle Cotterchio Eithne Costello Joanne Elena Ugo Boggi J Michael Gaziano Maria Gazouli Edward L Giovannucci Michael Goggins Myron Gross Christopher A Haiman Manal Hassan Kathy J Helzlsouer Nan Hu David J Hunter Elzbieta Iskierka-Jazdzewska Mazda Jenab Rudolf Kaaks Timothy J Key Kay-Tee Khaw Eric A Klein Manolis Kogevinas Vittorio Krogh Juozas Kupcinskas Robert C Kurtz Maria T Landi Stefano Landi Loic Le Marchand Andrea Mambrini Satu Mannisto Roger L Milne Rachel E Neale Ann L Oberg Salvatore Panico Alpa V Patel Petra H M Peeters Ulrike Peters Raffaele Pezzilli Miquel Porta Mark Purdue J Ramón Quiros Elio Riboli Nathaniel Rothman Aldo Scarpa Ghislaine Scelo Xiao-Ou Shu Debra T Silverman Pavel Soucek Oliver Strobel Malin Sund Ewa Małecka-Panas Philip R Taylor Francesca Tavano Ruth C Travis Mark Thornquist Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Yogesh Vashist Pavel Vodicka Jean Wactawski-Wende Nicolas Wentzensen Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Charles Kooperberg Harvey A Risch Eric J Jacobs Donghui Li Charles Fuchs Robert Hoover Patricia Hartge Stephen J Chanock Gloria M Petersen Rachael S Stolzenberg-Solomon Brian M Wolpin Peter Kraft Alison P Klein Federico Canzian Laufey T Amundadottir

Oncotarget 2016 Oct;7(41):66328-66343

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.18632/oncotarget.11041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340084PMC
October 2016

Nurses' Health Study Contributions on the Epidemiology of Less Common Cancers: Endometrial, Ovarian, Pancreatic, and Hematologic.

Am J Public Health 2016 Sep 26;106(9):1608-15. Epub 2016 Jul 26.

Brenda M. Birmann, Ying Bao, Marta Crous-Bou, Immaculata De Vivo, and Shelley S. Tworoger are with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Mollie E. Barnard is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston. Kimberly A. Bertrand is with the Slone Epidemiology Center, Boston University, Boston. Brian M. Wolpin is with the Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School.

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http://dx.doi.org/10.2105/AJPH.2016.303337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981809PMC
September 2016

Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report.

Pancreas 2016 09;45(8):1080-91

From the *Division of Cancer Prevention, National Cancer Institute, Bethesda, MD; †Department of Surgery, David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY; ‡Division of Gastroenterology, University of Washington at Seattle, Seattle, WA; §Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD; ∥Department of Epidemiology, Health Sciences Research, Mayo Clinic, Rochester, MN; ¶Department of Medicine, Center for Cancer Prevention and Drug Development Program, PC Stephenson Oklahoma Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK; #Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA; **Department of Medicine, Mayo Clinic, Rochester, MN; ††Department of Oncology, National Familial Pancreas Tumor Registry, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD; ‡‡Department of Surgery, Pancreatic Cancer Center, University of Michigan, Ann Arbor, MI; §§Department of Internal Medicine, Pancreatic Cancer Center, University of Michigan, Ann Arbor, MI; ∥∥Department of Surgery, Translational Oncology Program, Pancreatic Cancer Center, University of Michigan, Ann Arbor, MI; and ¶¶Department of Medicine, Pancreatic Tumor Center, Dana-Farber Cancer Institute, Harvard Medical School, Cambridge, MA.

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https://insights.ovid.com/crossref?an=00006676-201609000-000
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http://dx.doi.org/10.1097/MPA.0000000000000705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988336PMC
September 2016

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.

Science 2016 09;353(6304):1161-5

Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Broad Institute, Seven Cambridge Center, Cambridge, MA 02142, USA. Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/science.aaf5171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245791PMC
September 2016

Prediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival.

J Clin Oncol 2016 08 20;34(24):2899-905. Epub 2016 Jun 20.

Chen Yuan, Zhi Rong Qian, Ana Babic, Vicente Morales-Oyarvide, Douglas A. Rubinson, Kimmie Ng, Shuji Ogino, Charles S. Fuchs, and Brian M. Wolpin, Dana-Farber Cancer Institute and Harvard Medical School; Peter Kraft, Edward L. Giovannucci, Shuji Ogino, Meir J. Stampfer, Howard D. Sesso, Julie E. Buring, and JoAnn E. Manson, Harvard School of Public Health; Ying Bao, Edward L. Giovannucci, Shuji Ogino, Meir J. Stampfer, John Michael Gaziano, Howard D. Sesso, JoAnn E. Manson, and Charles S. Fuchs, Brigham and Women's Hospital and Harvard Medical School; John Michael Gaziano, Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA; Barbara B. Cochrane, University of Washington School of Nursing, Seattle, WA; Rowan T. Chlebowski, Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles Medical Center, Torrance, CA; and Linda G. Snetselaar, University of Iowa College of Public Health, Iowa City, IA.

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http://dx.doi.org/10.1200/JCO.2015.66.3005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012662PMC
August 2016

Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study.

Cancer Epidemiol Biomarkers Prev 2016 07 16;25(7):1185-91. Epub 2016 May 16.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland. Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-1217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321211PMC
July 2016

Circulating Metabolites and Survival Among Patients With Pancreatic Cancer.

J Natl Cancer Inst 2016 Jun 11;108(6):djv409. Epub 2016 Jan 11.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (CY, ZRQ, DAR, KN, SO, MGVH, CSF, BMW); Broad Institute of MIT and Harvard University, Cambridge, MA (CBC, MGVH); Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China (CW); Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA (JRM, MET, MGVH); Department of Epidemiology (PK, SST, ELG, SO, MJS, JM, HDS, JEM), Department of Biostatistics (PK), and Department of Nutrition (ELG, MJS), Harvard School of Public Health, Boston, MA; Department of Pathology (SO), and Channing Division of Network Medicine (MKT, SST, YB, ELG, MJS, JM, JEM, CSF) and Division of Preventive Medicine (JMG, HDS, JEM), Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD (MZ, LTA); Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA (JMG); Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (GLA); University of Washington School of Nursing, Seattle, WA (BBC); Division of Genomic Stability and DNA repair, Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA (ACK).

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http://dx.doi.org/10.1093/jnci/djv409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849356PMC
June 2016

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.

Authors:
Mitchell J Machiela Weiyin Zhou Eric Karlins Joshua N Sampson Neal D Freedman Qi Yang Belynda Hicks Casey Dagnall Christopher Hautman Kevin B Jacobs Christian C Abnet Melinda C Aldrich Christopher Amos Laufey T Amundadottir Alan A Arslan Laura E Beane-Freeman Sonja I Berndt Amanda Black William J Blot Cathryn H Bock Paige M Bracci Louise A Brinton H Bas Bueno-de-Mesquita Laurie Burdett Julie E Buring Mary A Butler Federico Canzian Tania Carreón Kari G Chaffee I-Shou Chang Nilanjan Chatterjee Chu Chen Constance Chen Kexin Chen Charles C Chung Linda S Cook Marta Crous Bou Michael Cullen Faith G Davis Immaculata De Vivo Ti Ding Jennifer Doherty Eric J Duell Caroline G Epstein Jin-Hu Fan Jonine D Figueroa Joseph F Fraumeni Christine M Friedenreich Charles S Fuchs Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Mia M Gaudet J Michael Gaziano Graham G Giles Elizabeth M Gillanders Edward L Giovannucci Lynn Goldin Alisa M Goldstein Christopher A Haiman Goran Hallmans Susan E Hankinson Curtis C Harris Roger Henriksson Elizabeth A Holly Yun-Chul Hong Robert N Hoover Chao A Hsiung Nan Hu Wei Hu David J Hunter Amy Hutchinson Mazda Jenab Christoffer Johansen Kay-Tee Khaw Hee Nam Kim Yeul Hong Kim Young Tae Kim Alison P Klein Robert Klein Woon-Puay Koh Laurence N Kolonel Charles Kooperberg Peter Kraft Vittorio Krogh Robert C Kurtz Andrea LaCroix Qing Lan Maria Teresa Landi Loic Le Marchand Donghui Li Xiaolin Liang Linda M Liao Dongxin Lin Jianjun Liu Jolanta Lissowska Lingeng Lu Anthony M Magliocco Nuria Malats Keitaro Matsuo Lorna H McNeill Robert R McWilliams Beatrice S Melin Lisa Mirabello Lee Moore Sara H Olson Irene Orlow Jae Yong Park Ana Patiño-Garcia Beata Peplonska Ulrike Peters Gloria M Petersen Loreall Pooler Jennifer Prescott Ludmila Prokunina-Olsson Mark P Purdue You-Lin Qiao Preetha Rajaraman Francisco X Real Elio Riboli Harvey A Risch Benjamin Rodriguez-Santiago Avima M Ruder Sharon A Savage Fredrick Schumacher Ann G Schwartz Kendra L Schwartz Adeline Seow Veronica Wendy Setiawan Gianluca Severi Hongbing Shen Xin Sheng Min-Ho Shin Xiao-Ou Shu Debra T Silverman Margaret R Spitz Victoria L Stevens Rachael Stolzenberg-Solomon Daniel Stram Ze-Zhong Tang Philip R Taylor Lauren R Teras Geoffrey S Tobias David Van Den Berg Kala Visvanathan Sholom Wacholder Jiu-Cun Wang Zhaoming Wang Nicolas Wentzensen William Wheeler Emily White John K Wiencke Brian M Wolpin Maria Pik Wong Chen Wu Tangchun Wu Xifeng Wu Yi-Long Wu Jay S Wunder Lucy Xia Hannah P Yang Pan-Chyr Yang Kai Yu Krista A Zanetti Anne Zeleniuch-Jacquotte Wei Zheng Baosen Zhou Regina G Ziegler Luis A Perez-Jurado Neil E Caporaso Nathaniel Rothman Margaret Tucker Michael C Dean Meredith Yeager Stephen J Chanock

Nat Commun 2016 06 13;7:11843. Epub 2016 Jun 13.

Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ncomms11843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909985PMC
June 2016

Impact of Pre-analytic Blood Sample Collection Factors on Metabolomics.

Cancer Epidemiol Biomarkers Prev 2016 05 3;25(5):823-829. Epub 2016 Mar 3.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873428PMC
May 2016

Circulating Exosomes in Pancreatic Cancer: Will They Succeed on the Long, Littered Road to Early Detection Marker?

Clin Chem 2016 Feb 31;62(2):307-9. Epub 2015 Dec 31.

Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, MA.

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http://intl.clinchem.org/content/early/2015/12/29/clinchem.2
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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2015.246538
Publisher Site
http://dx.doi.org/10.1373/clinchem.2015.246538DOI Listing
February 2016

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

Authors:
Joshua N Sampson William A Wheeler Meredith Yeager Orestis Panagiotou Zhaoming Wang Sonja I Berndt Qing Lan Christian C Abnet Laufey T Amundadottir Jonine D Figueroa Maria Teresa Landi Lisa Mirabello Sharon A Savage Philip R Taylor Immaculata De Vivo Katherine A McGlynn Mark P Purdue Preetha Rajaraman Hans-Olov Adami Anders Ahlbom Demetrius Albanes Maria Fernanda Amary She-Juan An Ulrika Andersson Gerald Andriole Irene L Andrulis Emanuele Angelucci Stephen M Ansell Cecilia Arici Bruce K Armstrong Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Nikolaus Becker Yolanda Benavente Simone Benhamou Christine Berg David Van Den Berg Leslie Bernstein Kimberly A Bertrand Brenda M Birmann Amanda Black Heiner Boeing Paolo Boffetta Marie-Christine Boutron-Ruault Paige M Bracci Louise Brinton Angela R Brooks-Wilson H Bas Bueno-de-Mesquita Laurie Burdett Julie Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Alfredo Carrato Tania Carreon Angela Carta John K C Chan Ellen T Chang Gee-Chen Chang I-Shou Chang Jiang Chang Jenny Chang-Claude Chien-Jen Chen Chih-Yi Chen Chu Chen Chung-Hsing Chen Constance Chen Hongyan Chen Kexin Chen Kuan-Yu Chen Kun-Chieh Chen Ying Chen Ying-Hsiang Chen Yi-Song Chen Yuh-Min Chen Li-Hsin Chien María-Dolores Chirlaque Jin Eun Choi Yi Young Choi Wong-Ho Chow Charles C Chung Jacqueline Clavel Françoise Clavel-Chapelon Pierluigi Cocco Joanne S Colt Eva Comperat Lucia Conde Joseph M Connors David Conti Victoria K Cortessis Michelle Cotterchio Wendy Cozen Simon Crouch Marta Crous-Bou Olivier Cussenot Faith G Davis Ti Ding W Ryan Diver Miren Dorronsoro Laure Dossus Eric J Duell Maria Grazia Ennas Ralph L Erickson Maria Feychting Adrienne M Flanagan Lenka Foretova Joseph F Fraumeni Neal D Freedman Laura E Beane Freeman Charles Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina García-Closas Randy D Gascoyne Julie Gastier-Foster Mia M Gaudet J Michael Gaziano Carol Giffen Graham G Giles Edward Giovannucci Bengt Glimelius Michael Goggins Nalan Gokgoz Alisa M Goldstein Richard Gorlick Myron Gross Robert Grubb Jian Gu Peng Guan Marc Gunter Huan Guo Thomas M Habermann Christopher A Haiman Dina Halai Goran Hallmans Manal Hassan Claudia Hattinger Qincheng He Xingzhou He Kathy Helzlsouer Brian Henderson Roger Henriksson Henrik Hjalgrim Judith Hoffman-Bolton Chancellor Hohensee Theodore R Holford Elizabeth A Holly Yun-Chul Hong Robert N Hoover Pamela L Horn-Ross G M Monawar Hosain H Dean Hosgood Chin-Fu Hsiao Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang Jose-Maria Huerta Jen-Yu Hung Amy Hutchinson Peter D Inskip Rebecca D Jackson Eric J Jacobs Mazda Jenab Hyo-Sung Jeon Bu-Tian Ji Guangfu Jin Li Jin Christoffer Johansen Alison Johnson Yoo Jin Jung Rudolph Kaaks Aruna Kamineni Eleanor Kane Chang Hyun Kang Margaret R Karagas Rachel S Kelly Kay-Tee Khaw Christopher Kim Hee Nam Kim Jin Hee Kim Jun Suk Kim Yeul Hong Kim Young Tae Kim Young-Chul Kim Cari M Kitahara Alison P Klein Robert J Klein Manolis Kogevinas Takashi Kohno Laurence N Kolonel Charles Kooperberg Anne Kricker Vittorio Krogh Hideo Kunitoh Robert C Kurtz Sun-Seog Kweon Andrea LaCroix Charles Lawrence Fernando Lecanda Victor Ho Fun Lee Donghui Li Haixin Li Jihua Li Yao-Jen Li Yuqing Li Linda M Liao Mark Liebow Tracy Lightfoot Wei-Yen Lim Chien-Chung Lin Dongxin Lin Sara Lindstrom Martha S Linet Brian K Link Chenwei Liu Jianjun Liu Li Liu Börje Ljungberg Josep Lloreta Simonetta Di Lollo Daru Lu Eiluv Lund Nuria Malats Satu Mannisto Loic Le Marchand Neyssa Marina Giovanna Masala Giuseppe Mastrangelo Keitaro Matsuo Marc Maynadie James McKay Roberta McKean-Cowdin Mads Melbye Beatrice S Melin Dominique S Michaud Tetsuya Mitsudomi Alain Monnereau Rebecca Montalvan Lee E Moore Lotte Maxild Mortensen Alexandra Nieters Kari E North Anne J Novak Ann L Oberg Kenneth Offit In-Jae Oh Sara H Olson Domenico Palli William Pao In Kyu Park Jae Yong Park Kyong Hwa Park Ana Patiño-Garcia Sofia Pavanello Petra H M Peeters Reury-Perng Perng Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Ludmila Prokunina-Olsson Biyun Qian You-Lin Qiao Marco Rais Elio Riboli Jacques Riby Harvey A Risch Cosmeri Rizzato Rebecca Rodabough Eve Roman Morgan Roupret Avima M Ruder Silvia de Sanjose Ghislaine Scelo Alan Schned Fredrick Schumacher Kendra Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Veronica Wendy Setiawan Gianluca Severi Richard K Severson Tait D Shanafelt Hongbing Shen Wei Shen Min-Ho Shin Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesúmaga Alan Dart Loon Sihoe Christine F Skibola Alex Smith Martyn T Smith Melissa C Southey John J Spinelli Anthony Staines Meir Stampfer Marianna C Stern Victoria L Stevens Rachael S Stolzenberg-Solomon Jian Su Wu-Chou Su Malin Sund Jae Sook Sung Sook Whan Sung Wen Tan Wei Tang Adonina Tardón David Thomas Carrie A Thompson Lesley F Tinker Roberto Tirabosco Anne Tjønneland Ruth C Travis Dimitrios Trichopoulos Fang-Yu Tsai Ying-Huang Tsai Margaret Tucker Jenny Turner Claire M Vajdic Roel C H Vermeulen Danylo J Villano Paolo Vineis Jarmo Virtamo Kala Visvanathan Jean Wactawski-Wende Chaoyu Wang Chih-Liang Wang Jiu-Cun Wang Junwen Wang Fusheng Wei Elisabete Weiderpass George J Weiner Stephanie Weinstein Nicolas Wentzensen Emily White Thomas E Witzig Brian M Wolpin Maria Pik Wong Chen Wu Guoping Wu Junjie Wu Tangchun Wu Wei Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Ping Xu Pan-Chyr Yang Tsung-Ying Yang Yuanqing Ye Zhihua Yin Jun Yokota Ho-Il Yoon Chong-Jen Yu Herbert Yu Kai Yu Jian-Min Yuan Andrew Zelenetz Anne Zeleniuch-Jacquotte Xu-Chao Zhang Yawei Zhang Xueying Zhao Zhenhong Zhao Hong Zheng Tongzhang Zheng Wei Zheng Baosen Zhou Meng Zhu Mariagrazia Zucca Simina M Boca James R Cerhan Giovanni M Ferri Patricia Hartge Chao Agnes Hsiung Corrado Magnani Lucia Miligi Lindsay M Morton Karin E Smedby Lauren R Teras Joseph Vijai Sophia S Wang Paul Brennan Neil E Caporaso David J Hunter Peter Kraft Nathaniel Rothman Debra T Silverman Susan L Slager Stephen J Chanock Nilanjan Chatterjee

J Natl Cancer Inst 2015 Dec 12;107(12):djv279. Epub 2015 Oct 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JNS, OP, SIB, QL, CCA, LTA, JDF, MTL, LM, SAS, PRT, KAM, PR, DA, DB, BAB, AB, LBr, WHC, CCC, JSC, JFFJr, NDF, LEBF, MGC, AMG, RNH, NH, WH, PDI, BTJ, CK, CMK, LML, MSL, LEM, LPO, RSSS, WeiT, MT, CWa, SW, NW, KY, PH, LMM, NEC, NR, DTS, SJC, NC); Information Management Services, Silver Spring, MD (WAW, CG); Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MD (MY, ZW, LBu, AH, CLi); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (IDV, KAB, BMB, CoC, MCB, CF, EG, SL, JP, MSt, DJH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (IDV, OA, KAB, CoC, MCB, EG, RSK, SL, JP, HDS, MSt, DTr, DJH, PK); Ontario Health Study, Toronto, Ontario, Canada (MPP); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (HOA, EWe); Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (AA, MF); UCL Cancer Institute, London, UK (MFA, AMF, DH); Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK (MFA, AMF, DH, RT); Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (SJA, JS, YLW, XCZ); Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden (UA, RH, BSM); Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, MO (GAJr, RGIII); Litwin Centre for Cancer Genetics, University of Toronto, Ontario, Canada (ILA, NG, JSW); Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (ILA, SG, NG, JSW); Hematology Unit, Ospedale Oncologico di Riferimento Regionale A. Businco, Cagliari, Italy (EA); Department of Medicin

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December 2015

TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.

Int J Cancer 2015 Nov 19;137(9):2175-83. Epub 2015 Jun 19.

Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548797PMC
November 2015

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.

Nat Genet 2015 Aug 22;47(8):911-6. Epub 2015 Jun 22.

1] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. [2] Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520746PMC
August 2015

Therapeutic Approaches for Metastatic Pancreatic Adenocarcinoma.

Hematol Oncol Clin North Am 2015 Aug 9;29(4):761-76. Epub 2015 Jun 9.

Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA; Pancreas and Biliary Tumor Center, Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. Electronic address:

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August 2015

Pancreatic Cancer.

Authors:
Brian M Wolpin

Hematol Oncol Clin North Am 2015 Aug;29(4):xiii-xiv

Center for Gastrointestinal Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA. Electronic address:

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August 2015

Reply to Y. Mao et al.

J Clin Oncol 2015 Jun 4;33(18):2121-2. Epub 2015 May 4.

Dana-Farber Cancer Institute; Brigham and Women's Hospital; and Harvard Medical School, Boston, MA

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June 2015

Characterization of large structural genetic mosaicism in human autosomes.

Authors:
Mitchell J Machiela Weiyin Zhou Joshua N Sampson Michael C Dean Kevin B Jacobs Amanda Black Louise A Brinton I-Shou Chang Chu Chen Constance Chen Kexin Chen Linda S Cook Marta Crous Bou Immaculata De Vivo Jennifer Doherty Christine M Friedenreich Mia M Gaudet Christopher A Haiman Susan E Hankinson Patricia Hartge Brian E Henderson Yun-Chul Hong H Dean Hosgood Chao A Hsiung Wei Hu David J Hunter Lea Jessop Hee Nam Kim Yeul Hong Kim Young Tae Kim Robert Klein Peter Kraft Qing Lan Dongxin Lin Jianjun Liu Loic Le Marchand Xiaolin Liang Jolanta Lissowska Lingeng Lu Anthony M Magliocco Keitaro Matsuo Sara H Olson Irene Orlow Jae Yong Park Loreall Pooler Jennifer Prescott Radhai Rastogi Harvey A Risch Fredrick Schumacher Adeline Seow Veronica Wendy Setiawan Hongbing Shen Xin Sheng Min-Ho Shin Xiao-Ou Shu David VanDen Berg Jiu-Cun Wang Nicolas Wentzensen Maria Pik Wong Chen Wu Tangchun Wu Yi-Long Wu Lucy Xia Hannah P Yang Pan-Chyr Yang Wei Zheng Baosen Zhou Christian C Abnet Demetrius Albanes Melinda C Aldrich Christopher Amos Laufey T Amundadottir Sonja I Berndt William J Blot Cathryn H Bock Paige M Bracci Laurie Burdett Julie E Buring Mary A Butler Tania Carreón Nilanjan Chatterjee Charles C Chung Michael B Cook Michael Cullen Faith G Davis Ti Ding Eric J Duell Caroline G Epstein Jin-Hu Fan Jonine D Figueroa Joseph F Fraumeni Neal D Freedman Charles S Fuchs Yu-Tang Gao Susan M Gapstur Ana Patiño-Garcia Montserrat Garcia-Closas J Michael Gaziano Graham G Giles Elizabeth M Gillanders Edward L Giovannucci Lynn Goldin Alisa M Goldstein Mark H Greene Goran Hallmans Curtis C Harris Roger Henriksson Elizabeth A Holly Robert N Hoover Nan Hu Amy Hutchinson Mazda Jenab Christoffer Johansen Kay-Tee Khaw Woon-Puay Koh Laurence N Kolonel Charles Kooperberg Vittorio Krogh Robert C Kurtz Andrea LaCroix Annelie Landgren Maria Teresa Landi Donghui Li Linda M Liao Nuria Malats Katherine A McGlynn Lorna H McNeill Robert R McWilliams Beatrice S Melin Lisa Mirabello Beata Peplonska Ulrike Peters Gloria M Petersen Ludmila Prokunina-Olsson Mark Purdue You-Lin Qiao Kari G Rabe Preetha Rajaraman Francisco X Real Elio Riboli Benjamín Rodríguez-Santiago Nathaniel Rothman Avima M Ruder Sharon A Savage Ann G Schwartz Kendra L Schwartz Howard D Sesso Gianluca Severi Debra T Silverman Margaret R Spitz Victoria L Stevens Rachael Stolzenberg-Solomon Daniel Stram Ze-Zhong Tang Philip R Taylor Lauren R Teras Geoffrey S Tobias Kala Viswanathan Sholom Wacholder Zhaoming Wang Stephanie J Weinstein William Wheeler Emily White John K Wiencke Brian M Wolpin Xifeng Wu Jay S Wunder Kai Yu Krista A Zanetti Anne Zeleniuch-Jacquotte Regina G Ziegler Mariza de Andrade Kathleen C Barnes Terri H Beaty Laura J Bierut Karl C Desch Kimberly F Doheny Bjarke Feenstra David Ginsburg John A Heit Jae H Kang Cecilia A Laurie Jun Z Li William L Lowe Mary L Marazita Mads Melbye Daniel B Mirel Jeffrey C Murray Sarah C Nelson Louis R Pasquale Kenneth Rice Janey L Wiggs Anastasia Wise Margaret Tucker Luis A Pérez-Jurado Cathy C Laurie Neil E Caporaso Meredith Yeager Stephen J Chanock

Am J Hum Genet 2015 Mar;96(3):487-97

Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA. Electronic address:

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March 2015

Survival among patients with pancreatic cancer and long-standing or recent-onset diabetes mellitus.

J Clin Oncol 2015 Jan 17;33(1):29-35. Epub 2014 Nov 17.

Chen Yuan, Douglas A. Rubinson, Zhi Rong Qian, Shuji Ogino, Kimmie Ng, Megan J. Gorman, Lauren K. Brais, Tingting Li, Matthew H. Kulke, Charles S. Fuchs, and Brian M. Wolpin, Dana-Farber Cancer Institute; Chen Wu, Peter Kraft, Shuji Ogino, Meir J. Stampfer, Frank B. Hu, and Edward L. Giovannucci, Harvard School of Public Health; and Ying Bao, Shuji Ogino, Kimmie Ng, Thomas E. Clancy, Richard S. Swanson, Meir J. Stampfer, Frank B. Hu, Edward L. Giovannucci, Matthew H. Kulke, Charles S. Fuchs, and Brian M. Wolpin, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2014.57.5688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268250PMC
January 2015

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.

Authors:
Zhaoming Wang Bin Zhu Mingfeng Zhang Hemang Parikh Jinping Jia Charles C Chung Joshua N Sampson Jason W Hoskins Amy Hutchinson Laurie Burdette Abdisamad Ibrahim Christopher Hautman Preethi S Raj Christian C Abnet Andrew A Adjei Anders Ahlbom Demetrius Albanes Naomi E Allen Christine B Ambrosone Melinda Aldrich Pilar Amiano Christopher Amos Ulrika Andersson Gerald Andriole Irene L Andrulis Cecilia Arici Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Laura E Beane Freeman Christine D Berg Sonja I Berndt Pier Alberto Bertazzi Richard B Biritwum Amanda Black William Blot Heiner Boeing Paolo Boffetta Kelly Bolton Marie-Christine Boutron-Ruault Paige M Bracci Paul Brennan Louise A Brinton Michelle Brotzman H Bas Bueno-de-Mesquita Julie E Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Guangwen Cao Neil E Caporaso Alfredo Carrato Tania Carreon Angela Carta Gee-Chen Chang I-Shou Chang Jenny Chang-Claude Xu Che Chien-Jen Chen Chih-Yi Chen Chung-Hsing Chen Constance Chen Kuan-Yu Chen Yuh-Min Chen Anand P Chokkalingam Lisa W Chu Francoise Clavel-Chapelon Graham A Colditz Joanne S Colt David Conti Michael B Cook Victoria K Cortessis E David Crawford Olivier Cussenot Faith G Davis Immaculata De Vivo Xiang Deng Ti Ding Colin P Dinney Anna Luisa Di Stefano W Ryan Diver Eric J Duell Joanne W Elena Jin-Hu Fan Heather Spencer Feigelson Maria Feychting Jonine D Figueroa Adrienne M Flanagan Joseph F Fraumeni Neal D Freedman Brooke L Fridley Charles S Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina Garcia-Closas Julie M Gastier-Foster J Michael Gaziano Daniela S Gerhard Carol A Giffen Graham G Giles Elizabeth M Gillanders Edward L Giovannucci Michael Goggins Nalan Gokgoz Alisa M Goldstein Carlos Gonzalez Richard Gorlick Mark H Greene Myron Gross H Barton Grossman Robert Grubb Jian Gu Peng Guan Christopher A Haiman Goran Hallmans Susan E Hankinson Curtis C Harris Patricia Hartge Claudia Hattinger Richard B Hayes Qincheng He Lee Helman Brian E Henderson Roger Henriksson Judith Hoffman-Bolton Chancellor Hohensee Elizabeth A Holly Yun-Chul Hong Robert N Hoover H Dean Hosgood Chin-Fu Hsiao Ann W Hsing Chao Agnes Hsiung Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang David J Hunter Peter D Inskip Hidemi Ito Eric J Jacobs Kevin B Jacobs Mazda Jenab Bu-Tian Ji Christoffer Johansen Mattias Johansson Alison Johnson Rudolf Kaaks Ashish M Kamat Aruna Kamineni Margaret Karagas Chand Khanna Kay-Tee Khaw Christopher Kim In-Sam Kim Jin Hee Kim Yeul Hong Kim Young-Chul Kim Young Tae Kim Chang Hyun Kang Yoo Jin Jung Cari M Kitahara Alison P Klein Robert Klein Manolis Kogevinas Woon-Puay Koh Takashi Kohno Laurence N Kolonel Charles Kooperberg Christian P Kratz Vittorio Krogh Hideo Kunitoh Robert C Kurtz Nilgun Kurucu Qing Lan Mark Lathrop Ching C Lau Fernando Lecanda Kyoung-Mu Lee Maxwell P Lee Loic Le Marchand Seth P Lerner Donghui Li Linda M Liao Wei-Yen Lim Dongxin Lin Jie Lin Sara Lindstrom Martha S Linet Jolanta Lissowska Jianjun Liu Börje Ljungberg Josep Lloreta Daru Lu Jing Ma Nuria Malats Satu Mannisto Neyssa Marina Giuseppe Mastrangelo Keitaro Matsuo Katherine A McGlynn Roberta McKean-Cowdin Lorna H McNeill Robert R McWilliams Beatrice S Melin Paul S Meltzer James E Mensah Xiaoping Miao Dominique S Michaud Alison M Mondul Lee E Moore Kenneth Muir Shelley Niwa Sara H Olson Nick Orr Salvatore Panico Jae Yong Park Alpa V Patel Ana Patino-Garcia Sofia Pavanello Petra H M Peeters Beata Peplonska Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Xia Pu Mark P Purdue You-Lin Qiao Preetha Rajaraman Elio Riboli Harvey A Risch Rebecca J Rodabough Nathaniel Rothman Avima M Ruder Jeong-Seon Ryu Marc Sanson Alan Schned Fredrick R Schumacher Ann G Schwartz Kendra L Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Gianluca Severi Hongbing Shen Min Shen Sanjay Shete Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesumaga Sabina Sierri Alan Dart Loon Sihoe Debra T Silverman Matthias Simon Melissa C Southey Logan Spector Margaret Spitz Meir Stampfer Par Stattin Mariana C Stern Victoria L Stevens Rachael Z Stolzenberg-Solomon Daniel O Stram Sara S Strom Wu-Chou Su Malin Sund Sook Whan Sung Anthony Swerdlow Wen Tan Hideo Tanaka Wei Tang Ze-Zhang Tang Adonina Tardon Evelyn Tay Philip R Taylor Yao Tettey David M Thomas Roberto Tirabosco Anne Tjonneland Geoffrey S Tobias Jorge R Toro Ruth C Travis Dimitrios Trichopoulos Rebecca Troisi Ann Truelove Ying-Huang Tsai Margaret A Tucker Rosario Tumino David Van Den Berg Stephen K Van Den Eeden Roel Vermeulen Paolo Vineis Kala Visvanathan Ulla Vogel Chaoyu Wang Chengfeng Wang Junwen Wang Sophia S Wang Elisabete Weiderpass Stephanie J Weinstein Nicolas Wentzensen William Wheeler Emily White John K Wiencke Alicja Wolk Brian M Wolpin Maria Pik Wong Margaret Wrensch Chen Wu Tangchun Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Hannah P Yang Pan-Chyr Yang Yasushi Yatabe Yuanqing Ye Edward D Yeboah Zhihua Yin Chen Ying Chong-Jen Yu Kai Yu Jian-Min Yuan Krista A Zanetti Anne Zeleniuch-Jacquotte Wei Zheng Baosen Zhou Lisa Mirabello Sharon A Savage Peter Kraft Stephen J Chanock Meredith Yeager Maria Terese Landi Jianxin Shi Nilanjan Chatterjee Laufey T Amundadottir

Hum Mol Genet 2014 Dec 15;23(24):6616-33. Epub 2014 Jul 15.

Division of Cancer Epidemiology and Genetics,

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December 2014

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

Authors:
Brian M Wolpin Cosmeri Rizzato Peter Kraft Charles Kooperberg Gloria M Petersen Zhaoming Wang Alan A Arslan Laura Beane-Freeman Paige M Bracci Julie Buring Federico Canzian Eric J Duell Steven Gallinger Graham G Giles Gary E Goodman Phyllis J Goodman Eric J Jacobs Aruna Kamineni Alison P Klein Laurence N Kolonel Matthew H Kulke Donghui Li Núria Malats Sara H Olson Harvey A Risch Howard D Sesso Kala Visvanathan Emily White Wei Zheng Christian C Abnet Demetrius Albanes Gabriella Andreotti Melissa A Austin Richard Barfield Daniela Basso Sonja I Berndt Marie-Christine Boutron-Ruault Michelle Brotzman Markus W Büchler H Bas Bueno-de-Mesquita Peter Bugert Laurie Burdette Daniele Campa Neil E Caporaso Gabriele Capurso Charles Chung Michelle Cotterchio Eithne Costello Joanne Elena Niccola Funel J Michael Gaziano Nathalia A Giese Edward L Giovannucci Michael Goggins Megan J Gorman Myron Gross Christopher A Haiman Manal Hassan Kathy J Helzlsouer Brian E Henderson Elizabeth A Holly Nan Hu David J Hunter Federico Innocenti Mazda Jenab Rudolf Kaaks Timothy J Key Kay-Tee Khaw Eric A Klein Manolis Kogevinas Vittorio Krogh Juozas Kupcinskas Robert C Kurtz Andrea LaCroix Maria T Landi Stefano Landi Loic Le Marchand Andrea Mambrini Satu Mannisto Roger L Milne Yusuke Nakamura Ann L Oberg Kouros Owzar Alpa V Patel Petra H M Peeters Ulrike Peters Raffaele Pezzilli Ada Piepoli Miquel Porta Francisco X Real Elio Riboli Nathaniel Rothman Aldo Scarpa Xiao-Ou Shu Debra T Silverman Pavel Soucek Malin Sund Renata Talar-Wojnarowska Philip R Taylor George E Theodoropoulos Mark Thornquist Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Pavel Vodicka Jean Wactawski-Wende Nicolas Wentzensen Chen Wu Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Robert Hoover Patricia Hartge Charles Fuchs Stephen J Chanock Rachael S Stolzenberg-Solomon Laufey T Amundadottir

Nat Genet 2014 Sep 3;46(9):994-1000. Epub 2014 Aug 3.

1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. [2].

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September 2014

Pancreatic adenocarcinoma, version 2.2014: featured updates to the NCCN guidelines.

J Natl Compr Canc Netw 2014 Aug;12(8):1083-93

From UCSF Helen Diller Family Comprehensive Cancer Center; Moffitt Cancer Center; St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Memorial Sloan Kettering Cancer Center; Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance; City of Hope Comprehensive Cancer Center; Fox Chase Cancer Center; Duke Cancer Institute; Pancreatic Cancer Action Network (PanCAN); University of Michigan Comprehensive Cancer Center; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Stanford Cancer Institute; UC San Diego Moores Cancer Center; Roswell Park Cancer Institute; Vanderbilt-Ingram Cancer Center; Huntsman Cancer Institute at the University of Utah; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; Massachusetts General Hospital Cancer Center; University of Alabama at Birmingham Comprehensive Cancer Center; Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center; University of Colorado Cancer Center; The University of Texas MD Anderson Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; and National Comprehensive Cancer Network.

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August 2014

Managing advanced colorectal cancer: have we reached the PEAK with current therapies?

J Clin Oncol 2014 Jul 16;32(21):2200-2. Epub 2014 Jun 16.

Dana-Farber Cancer Institute; Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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July 2014

An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population.

PLoS One 2013 13;8(9):e72311. Epub 2013 Sep 13.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America ; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America ; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772857PMC
June 2014

Variants associated with susceptibility to pancreatic cancer and melanoma do not reciprocally affect risk.

Cancer Epidemiol Biomarkers Prev 2014 Jun 18;23(6):1121-4. Epub 2014 Mar 18.

Authors' Affiliations: Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland; Departments of Obstetrics and Gynecology and Environmental Medicine, New York University School of Medicine, New York, New York; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; and Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120837PMC
June 2014

Reproducibility of metabolomic profiles among men and women in 2 large cohort studies.

Clin Chem 2013 Nov 29;59(11):1657-67. Epub 2013 Jul 29.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA;

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http://dx.doi.org/10.1373/clinchem.2012.199133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812240PMC
November 2013

Prediagnostic body mass index and pancreatic cancer survival.

J Clin Oncol 2013 Nov 21;31(33):4229-34. Epub 2013 Oct 21.

Chen Yuan, Shuji Ogino, Kimmie Ng, Zhi Rong Qian, Douglas A. Rubinson, and Brian M. Wolpin, Dana-Farber Cancer Institute; Ying Bao, Shuji Ogino, Kimmie Ng, Meir J. Stampfer, Edward L. Giovannucci, and Brian M. Wolpin, Brigham and Women's Hospital, Harvard Medical School; and Chen Wu, Peter Kraft, Shuji Ogino, Meir J. Stampfer, and Edward L. Giovannucci, Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2013.51.7532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821012PMC
November 2013

Inflammatory plasma markers and pancreatic cancer risk: a prospective study of five U.S. cohorts.

Cancer Epidemiol Biomarkers Prev 2013 May 5;22(5):855-61. Epub 2013 Mar 5.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650127PMC
May 2013

Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4.

Cancer Causes Control 2013 Mar 19;24(3):595-602. Epub 2013 Jan 19.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK.

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http://dx.doi.org/10.1007/s10552-012-0138-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127987PMC
March 2013

A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts.

J Natl Cancer Inst 2013 Jan 14;105(2):95-103. Epub 2012 Dec 14.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/jnci/djs474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545904PMC
January 2013

Phase I study of pasireotide (SOM 230) and everolimus (RAD001) in advanced neuroendocrine tumors.

Endocr Relat Cancer 2012 Oct 14;19(5):615-23. Epub 2012 Sep 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1530/ERC-11-0382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469068PMC
October 2012

Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer.

Carcinogenesis 2012 Jul 20;33(7):1384-90. Epub 2012 Apr 20.

Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1093/carcin/bgs151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405651PMC
July 2012

ABO blood group and breast cancer incidence and survival.

Int J Cancer 2012 May 10;130(9):2129-37. Epub 2012 Feb 10.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/ijc.26220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655700PMC
May 2012

Detectable clonal mosaicism and its relationship to aging and cancer.

Authors:
Kevin B Jacobs Meredith Yeager Weiyin Zhou Sholom Wacholder Zhaoming Wang Benjamin Rodriguez-Santiago Amy Hutchinson Xiang Deng Chenwei Liu Marie-Josephe Horner Michael Cullen Caroline G Epstein Laurie Burdett Michael C Dean Nilanjan Chatterjee Joshua Sampson Charles C Chung Joseph Kovaks Susan M Gapstur Victoria L Stevens Lauren T Teras Mia M Gaudet Demetrius Albanes Stephanie J Weinstein Jarmo Virtamo Philip R Taylor Neal D Freedman Christian C Abnet Alisa M Goldstein Nan Hu Kai Yu Jian-Min Yuan Linda Liao Ti Ding You-Lin Qiao Yu-Tang Gao Woon-Puay Koh Yong-Bing Xiang Ze-Zhong Tang Jin-Hu Fan Melinda C Aldrich Christopher Amos William J Blot Cathryn H Bock Elizabeth M Gillanders Curtis C Harris Christopher A Haiman Brian E Henderson Laurence N Kolonel Loic Le Marchand Lorna H McNeill Benjamin A Rybicki Ann G Schwartz Lisa B Signorello Margaret R Spitz John K Wiencke Margaret Wrensch Xifeng Wu Krista A Zanetti Regina G Ziegler Jonine D Figueroa Montserrat Garcia-Closas Nuria Malats Gaelle Marenne Ludmila Prokunina-Olsson Dalsu Baris Molly Schwenn Alison Johnson Maria Teresa Landi Lynn Goldin Dario Consonni Pier Alberto Bertazzi Melissa Rotunno Preetha Rajaraman Ulrika Andersson Laura E Beane Freeman Christine D Berg Julie E Buring Mary A Butler Tania Carreon Maria Feychting Anders Ahlbom J Michael Gaziano Graham G Giles Goran Hallmans Susan E Hankinson Patricia Hartge Roger Henriksson Peter D Inskip Christoffer Johansen Annelie Landgren Roberta McKean-Cowdin Dominique S Michaud Beatrice S Melin Ulrike Peters Avima M Ruder Howard D Sesso Gianluca Severi Xiao-Ou Shu Kala Visvanathan Emily White Alicja Wolk Anne Zeleniuch-Jacquotte Wei Zheng Debra T Silverman Manolis Kogevinas Juan R Gonzalez Olaya Villa Donghui Li Eric J Duell Harvey A Risch Sara H Olson Charles Kooperberg Brian M Wolpin Li Jiao Manal Hassan William Wheeler Alan A Arslan H Bas Bueno-de-Mesquita Charles S Fuchs Steven Gallinger Myron D Gross Elizabeth A Holly Alison P Klein Andrea LaCroix Margaret T Mandelson Gloria Petersen Marie-Christine Boutron-Ruault Paige M Bracci Federico Canzian Kenneth Chang Michelle Cotterchio Edward L Giovannucci Michael Goggins Judith A Hoffman Bolton Mazda Jenab Kay-Tee Khaw Vittorio Krogh Robert C Kurtz Robert R McWilliams Julie B Mendelsohn Kari G Rabe Elio Riboli Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Joanne W Elena Herbert Yu Laufey Amundadottir Rachael Z Stolzenberg-Solomon Peter Kraft Fredrick Schumacher Daniel Stram Sharon A Savage Lisa Mirabello Irene L Andrulis Jay S Wunder Ana Patiño García Luis Sierrasesúmaga Donald A Barkauskas Richard G Gorlick Mark Purdue Wong-Ho Chow Lee E Moore Kendra L Schwartz Faith G Davis Ann W Hsing Sonja I Berndt Amanda Black Nicolas Wentzensen Louise A Brinton Jolanta Lissowska Beata Peplonska Katherine A McGlynn Michael B Cook Barry I Graubard Christian P Kratz Mark H Greene Ralph L Erickson David J Hunter Gilles Thomas Robert N Hoover Francisco X Real Joseph F Fraumeni Neil E Caporaso Margaret Tucker Nathaniel Rothman Luis A Pérez-Jurado Stephen J Chanock

Nat Genet 2012 May 6;44(6):651-8. Epub 2012 May 6.

Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), Rockville, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372921PMC
May 2012

Dietary insulin load, dietary insulin index, and risk of pancreatic cancer.

Am J Clin Nutr 2011 Sep 20;94(3):862-8. Epub 2011 Jul 20.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.3945/ajcn.110.011205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155930PMC
September 2011

ABO blood group and risk of colorectal cancer.

Cancer Epidemiol Biomarkers Prev 2011 May 17;20(5):1017-20. Epub 2011 Mar 17.

Division of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-1250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089692PMC
May 2011

Rapid progression of combined hepatocellular carcinoma and cholangiocarcinoma.

Cancer Imaging 2011 Mar 31;11:37-41. Epub 2011 Mar 31.

Department of Radiology, Dana Farber Cancer Institute, Harvard Medical School, and Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1102/1470-7330.2011.0009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080125PMC
March 2011

ABO blood group and incidence of epithelial ovarian cancer.

Int J Cancer 2011 Jan 22;128(2):482-6. Epub 2010 Mar 22.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/ijc.25339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946962PMC
January 2011

Prospective study of ABO blood type and the risk of pulmonary embolism in two large cohort studies.

Thromb Haemost 2010 Nov 30;104(5):962-71. Epub 2010 Sep 30.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1160/TH10-05-0312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150546PMC
November 2010

A step forward in the treatment of advanced biliary tract cancer.

N Engl J Med 2010 Apr;362(14):1335-7

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http://dx.doi.org/10.1056/NEJMe1001183DOI Listing
April 2010

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.

Nat Genet 2010 Mar 24;42(3):224-8. Epub 2010 Jan 24.

Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/ng.522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853179PMC
March 2010

Clinical problem-solving. The writing on the wall.

N Engl J Med 2009 Oct;361(14):1387-92

Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1056/NEJMcps0707685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774010PMC
October 2009