Brian M Suzuki

Brian M Suzuki

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Brian M Suzuki

Brian M Suzuki

Publications by authors named "Brian M Suzuki"

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Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.

ACS Chem Biol 2020 Mar 28;15(3):751-757. Epub 2020 Jan 28.

Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/acschembio.9b00992DOI Listing
March 2020

Bioactivity of Farnesyltransferase Inhibitors Against and .

Front Cell Infect Microbiol 2019 29;9:180. Epub 2019 May 29.

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fcimb.2019.00180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548881PMC
January 2020

The Proteasome as a Drug Target in the Metazoan Pathogen, .

ACS Infect Dis 2019 10 12;5(10):1802-1812. Epub 2019 Aug 12.

Center for Discovery and Innovation in Parasitic Diseases , University of California, San Diego , 9500 Gilman Drive , La Jolla , California 92093 , United States.

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http://dx.doi.org/10.1021/acsinfecdis.9b00237DOI Listing
October 2019

Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery.

Parasit Vectors 2019 Oct 22;12(1):493. Epub 2019 Oct 22.

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1186/s13071-019-3747-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805474PMC
October 2019

TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling.

Int J Parasitol Drugs Drug Resist 2018 12 20;8(3):571-586. Epub 2018 Nov 20.

Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2018.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287543PMC
December 2018

Effect of Phenotypic Screening of Extracts and Fractions of Leaf and Stem Bark on Immature and Adult Stages of .

J Parasitol Res 2018 7;2018:9431467. Epub 2018 Jun 7.

Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1155/2018/9431467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011076PMC
June 2018

Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria.

PLoS Negl Trop Dis 2016 08 8;10(8):e0004893. Epub 2016 Aug 8.

Skaggs School of Pharmacy and Pharmaceutical Chemistry, University of California, San Diego, La Jolla, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976874PMC
August 2016

Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo.

Pharmaceuticals (Basel) 2016 Jul 4;9(3). Epub 2016 Jul 4.

Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, CA 94158, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039492PMC
http://dx.doi.org/10.3390/ph9030039DOI Listing
July 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.

PLoS Negl Trop Dis 2016 Jan 11;10(1):e0004356. Epub 2016 Jan 11.

Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709140PMC
January 2016

Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil.

PLoS Negl Trop Dis 2016 Jan 11;10(1):e0004357. Epub 2016 Jan 11.

Center for Discovery and Innovation in Parasitic Diseases and the Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709075PMC
January 2016

Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni.

Molecules 2015 Jun 12;20(6):10873-83. Epub 2015 Jun 12.

Institute of Pharmacy and Food Chemistry, University of Wuerzburg, Am Hubland, D-97074 Wuerzburg, Germany.

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http://dx.doi.org/10.3390/molecules200610873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272620PMC
June 2015

The QDREC web server: determining dose-response characteristics of complex macroparasites in phenotypic drug screens.

Bioinformatics 2015 May 24;31(9):1515-8. Epub 2014 Dec 24.

Department of Computer Science, San Francisco State University, San Francisco, CA, USA, Department of Pathology and Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, CA, USA Department of Computer Science, San Francisco State University, San Francisco, CA, USA, Department of Pathology and Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, CA, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btu831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410654PMC
May 2015

Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis.

PLoS One 2014 29;9(1):e87594. Epub 2014 Jan 29.

Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087594PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906178PMC
October 2014