Brian Kavanagh

Brian Kavanagh

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Brian Kavanagh

Brian Kavanagh

Publications by authors named "Brian Kavanagh"

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Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats.

Anesthesiology 2020 Jan;132(1):140-154

From the Keenan Research Centre for Biomedical Science, St. Michael's Hospital (M.J., S.G., R.R., T.W.-A., C.M., G.F.C., J.M., J.G.L.) Departments of Surgery and Interdepartmental Division of Critical Care (J.M.) Departments of Anesthesia, Physiology and Interdepartmental Division of Critical Care (B.P.K., J.G.L.), University of Toronto, Toronto, Canada Regenerative Medicine Institute at CÚRAM Centre for Research in Medical Devices, National University of Ireland Galway, Galway, Ireland (C.M., J.G.L.) Translational Medicine (G.O.) Department of Critical Care Medicine (B.P.K.), Hospital for Sick Children, Toronto, Canada Departments of Anesthesia and Critical Care Medicine, St. Michael's Hospital, Toronto, Canada (G.F.C., J.G.L.) Department of Anesthesia and Critical Care, Royal College of Surgeons in Ireland, Dublin, Ireland (G.F.C.).

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http://dx.doi.org/10.1097/ALN.0000000000003018DOI Listing
January 2020

Electromagnetic wave propagation in a fast pulse line ion accelerator.

Med Phys 2019 Dec 4;46(12):5714-5721. Epub 2019 Nov 4.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1002/mp.13875DOI Listing
December 2019

Effect of grid geometry on the transmission properties of 2D grids for flat detectors in CBCT.

Phys Med Biol 2019 11 15;64(22):225006. Epub 2019 Nov 15.

Author to whom correspondence should be addressed.

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http://dx.doi.org/10.1088/1361-6560/ab4af4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937210PMC
November 2019

Impact of Radiation Dose to the Host Immune System on Tumor Control and Survival for Stage III Non-Small Cell Lung Cancer Treated with Definitive Radiation Therapy.

Int J Radiat Oncol Biol Phys 2019 10 5;105(2):346-355. Epub 2019 Jun 5.

Department of Radiation Oncology, Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.05.064DOI Listing
October 2019

Imaging the Injured Lung: Mechanisms of Action and Clinical Use.

Anesthesiology 2019 09;131(3):716-749

From the Department of Anesthesiology and Critical Care and the Department of Radiology (M.C., Y.X., R.R.R.), University of Pennsylvania, Philadelphia, Pennsylvania the Interdepartmental Division of Critical Care Medicine and Department of Medicine (A.G.) Hospital for Sick Children (B.P.K., T.Y.), University of Toronto, Toronto, Ontario, Canada the Departments of Anesthesia and Biomedical Engineering (J.H.) Anesthesia, Radiology, and Biomedical Engineering (D.W.K.), University of Iowa, Iowa City, Iowa the Hedenstierna Laboratory and Uppsala University Hospital, Uppsala University, Uppsala, Sweden (G.P.).

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http://dx.doi.org/10.1097/ALN.0000000000002583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692186PMC
September 2019

Phase II study of stereotactic radiosurgery for the treatment of patients with oligoprogression on erlotinib.

Cancer Treat Res Commun 2019 26;19:100126. Epub 2019 Feb 26.

Lineberger Cancer Center at the University of North Carolina, 170 Manning Drive, Room 3115, Campus Box 7305, Chapel Hill, NC 27514, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ctarc.2019.100126DOI Listing
September 2019

Driving Pressure Is Associated with Outcome during Assisted Ventilation in Acute Respiratory Distress Syndrome.

Anesthesiology 2019 09;131(3):594-604

From the Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy (G.B., A.G., S.S., S.G., G.F.) Department of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy (G.B., A.G., S.S., S.G., G.F.) Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada (B.P.K.) Department of Anesthesia, Critical Care and Emergency Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy (A.P.).

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http://dx.doi.org/10.1097/ALN.0000000000002846DOI Listing
September 2019

Radiation Oncology APM: Why Us? Why Now?

Authors:
Brian Kavanagh

Int J Radiat Oncol Biol Phys 2019 09 11;105(1):22-24. Epub 2019 Jul 11.

Department of Radiation Oncology, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.07.002DOI Listing
September 2019

Halfway Toward Half Full.

Int J Radiat Oncol Biol Phys 2019 08;104(5):997-998

Department of Radiation Oncology, University of Colorado, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.05.061DOI Listing
August 2019

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

N Engl J Med 2019 08;381(8):786-787

University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1056/NEJMc1908874DOI Listing
August 2019

Model Insurance Coverage Policies: The Power of Suggestion, the Force of Evidence.

Int J Radiat Oncol Biol Phys 2019 07;104(4):745-747

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.ijrobp.2019.04.004DOI Listing
July 2019

Overexpression of IL-10 Enhances the Efficacy of Human Umbilical-Cord-Derived Mesenchymal Stromal Cells in Pneumosepsis.

J Clin Med 2019 Jun 13;8(6). Epub 2019 Jun 13.

Regenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, Biomedical Sciences Building, National University of Ireland Galway, Galway H91 TK33, Ireland.

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https://www.mdpi.com/2077-0383/8/6/847
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http://dx.doi.org/10.3390/jcm8060847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616885PMC
June 2019

A novel total variation based ring artifact suppression method for CBCT imaging with two-dimensional antiscatter grids.

Med Phys 2019 May 20;46(5):2181-2193. Epub 2019 Mar 20.

Department of Radiation Oncology, University of Colorado School of Medicine, 1665 Aurora Court, Suite 1032, Mail stop F-706, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1002/mp.13456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559363PMC
May 2019

Impact of spontaneous breathing during mechanical ventilation in acute respiratory distress syndrome.

Curr Opin Crit Care 2019 04;25(2):192-198

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1097/MCC.0000000000000597DOI Listing
April 2019

Can a Physiologic Insight "Resuscitate" Research in Cardiopulmonary Resuscitation?

Am J Respir Crit Care Med 2019 Mar;199(6):682-684

3 The Research Institute and Department of Critical Care Medicine Hospital for Sick Children Toronto, Ontario, Canada and.

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http://dx.doi.org/10.1164/rccm.201810-1912EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423109PMC
March 2019

Reply to Santini et al.: High Positive End-Expiratory Pressure: Only a Dam against Edema Formation? Probably Not (Again).

Am J Respir Crit Care Med 2019 02;199(4):544

1 Hospital for Sick Children Toronto, Ontario, Canada.

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http://dx.doi.org/10.1164/rccm.201810-2000LEDOI Listing
February 2019

Impact of Altered Airway Pressure on Intracranial Pressure, Perfusion, and Oxygenation: A Narrative Review.

Crit Care Med 2019 02;47(2):254-263

Translational Medicine, The Research Institute, Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000003558DOI Listing
February 2019

Could nanotechnology make vitamin E therapeutically effective?

Am J Physiol Lung Cell Mol Physiol 2019 01 8;316(1):L1-L5. Epub 2018 Nov 8.

Program in Translational Medicine, The Research Institute, and the Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto , Toronto , Canada.

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http://dx.doi.org/10.1152/ajplung.00430.2018DOI Listing
January 2019

Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure.

Lancet Respir Med 2019 01 16;7(1):90-98. Epub 2018 Nov 16.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada; Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Physiology, University of Toronto, Toronto, ON, Canada; Department of Medicine, Division of Respirology, University Health Network, Toronto, ON, Canada; Toronto General Hospital Research Institute, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S22132600183036
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http://dx.doi.org/10.1016/S2213-2600(18)30366-7DOI Listing
January 2019

Understanding spontaneous vs. ventilator breaths: impact and monitoring.

Intensive Care Med 2018 Dec 24;44(12):2235-2238. Epub 2018 Mar 24.

Translational Medicine, Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Canada.

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http://link.springer.com/10.1007/s00134-018-5145-5
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http://dx.doi.org/10.1007/s00134-018-5145-5DOI Listing
December 2018

Abrupt Deflation after Sustained Inflation Causes Lung Injury.

Am J Respir Crit Care Med 2018 11;198(9):1165-1176

1 Translational Medicine, The Research Institute.

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http://dx.doi.org/10.1164/rccm.201801-0178OCDOI Listing
November 2018

Reverse Triggering Causes an Injurious Inflation Pattern during Mechanical Ventilation.

Am J Respir Crit Care Med 2018 10;198(8):1096-1099

2 University of Toronto Toronto, Ontario, Canada.

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http://dx.doi.org/10.1164/rccm.201804-0649LEDOI Listing
October 2018

Declaration of conflicts of interest: a 'crooked' line towards scientific integrity.

Intensive Care Med 2018 Oct 3;44(10):1732-1734. Epub 2018 Sep 3.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1007/s00134-018-5358-7DOI Listing
October 2018

Cardiopulmonary Adaptation During First Day of Life in Human Neonates.

J Pediatr 2018 09 24;200:50-57.e2. Epub 2018 May 24.

Division of Neonatology, The Hospital for Sick Children, Toronto, Ontario, Canada; Critical Care, The Hospital for Sick Children, Toronto, Ontario, Canada; School of Medicine (Department of Paediatrics), The Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jpeds.2018.04.051DOI Listing
September 2018

Negative trials in critical care: why most research is probably wrong.

Lancet Respir Med 2018 09 27;6(9):659-660. Epub 2018 Jul 27.

Department of Anaesthesia, Department of Physiology, and Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON M5G 1X8, Canada; Department of Critical Care Medicine, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30279-0DOI Listing
September 2018

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors.

Anesthesiology 2018 07;129(1):143-153

From Translation Medicine (G.O., D.E., M.P., C.M., B.P.K.) the Departments of Critical Care Medicine and Anesthesia (B.P.K.) Hospital for Sick Children, and the Interdepartmental Division of Critical Care Medicine (B.P.K.), University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/ALN.0000000000002140DOI Listing
July 2018

Reply to Abrams et al. and to Duggal and Krishnan.

Am J Respir Crit Care Med 2018 07;198(1):141-142

1 University of Toronto Toronto, Canada.

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http://dx.doi.org/10.1164/rccm.201802-0371LEDOI Listing
July 2018

Continuous negative abdominal pressure: mechanism of action and comparison with prone position.

J Appl Physiol (1985) 2018 07 29;125(1):107-116. Epub 2018 Mar 29.

Physiology and Experimental Medicine, Hospital for Sick Children , Toronto, Ontario , Canada.

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http://dx.doi.org/10.1152/japplphysiol.01125.2017DOI Listing
July 2018

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model.

Anesthesiology 2018 07;129(1):163-172

From the Department of Translational Medicine (T.Y., D.E., G.O., B.K., M.P., B.P.K.) Departments of Critical Care Medicine and Anesthesia (T.Y., B.K., B.P.K.), Hospital for Sick Children, University of Toronto, Toronto, Canada Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada (T.Y., B.K., N.F., L.B., B.P.K.) Division of Respirology, Department of Medicine, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada (N.F.) Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (L.B.) the Cardio-Pulmonary Department, Pulmonary Division, Heart Institute (Incor), University of São Paulo, Brazil (M.A.).

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http://dx.doi.org/10.1097/ALN.0000000000002236DOI Listing
July 2018

From the Guest Editor: New Lenses, New Visions for Radiotherapy in the Molecular-Genetic-Immunomodulator Era of Oncology.

Authors:
Brian D Kavanagh

Cancer J 2016 Jul-Aug;22(4):245-6

From the Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1097/PPO.0000000000000211DOI Listing
June 2018

Honor Was Never Lost: The National Farm Machinery Show and the American Society for Radiation Oncology Annual Meeting.

Authors:
Brian D Kavanagh

Int J Radiat Oncol Biol Phys 2018 06;101(2):259-260

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.02.036DOI Listing
June 2018

Radiosurgery alone is associated with favorable outcomes for brain metastases from small-cell lung cancer.

Lung Cancer 2018 06 2;120:88-90. Epub 2018 Apr 2.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, United States. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.03.027DOI Listing
June 2018

Design considerations for a pulse line ion accelerator (PLIA)-based PET isotope generator.

Med Phys 2018 Jun 15. Epub 2018 Jun 15.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1002/mp.13050DOI Listing
June 2018

Unproven and Expensive before Proven and Cheap: Extracorporeal Membrane Oxygenation versus Prone Position in Acute Respiratory Distress Syndrome.

Am J Respir Crit Care Med 2018 04;197(8):991-993

1 Department of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1164/rccm.201711-2216CPDOI Listing
April 2018

Esophageal Manometry and Regional Transpulmonary Pressure in Lung Injury.

Am J Respir Crit Care Med 2018 04;197(8):1018-1026

2 Translational Medicine, Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, and.

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http://dx.doi.org/10.1164/rccm.201709-1806OCDOI Listing
April 2018

Implementation of hypofractionated prostate radiation therapy in the United States: A National Cancer Database analysis.

Pract Radiat Oncol 2017 Jul - Aug;7(4):270-278

Department of Radiation Oncology, University of Colorado Denver School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.prro.2017.03.011DOI Listing
March 2018

Post-Treatment Mortality After Surgery and Stereotactic Body Radiotherapy for Early-Stage Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 03 18;36(7):642-651. Epub 2018 Jan 18.

William A. Stokes, Michael R. Bronsert, Robert A. Meguid, Bernard L. Jones, Laurie E. Gaspar, Brian D. Kavanagh, and Chad G. Rusthoven, University of Colorado School of Medicine, Aurora; Matthew G. Blum, Memorial Hospital, Colorado Springs, CO; Matthew Koshy, University of Chicago School of Medicine, Chicago, IL; David J. Sher, University of Texas Southwestern School of Medicine, Dallas, TX; Alexander V. Louie and David A. Palma, London Health Sciences Centre, London, Ontario, Canada; and Suresh Senan, Vrije Universiteit University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2017.75.6536DOI Listing
March 2018

Two-dimensional antiscatter grid: A novel scatter rejection device for Cone-beam computed tomography.

Med Phys 2018 Feb 8;45(2):529-534. Epub 2018 Jan 8.

Department of Radiation Oncology, University of Colorado School of Medicine, 1665 Aurora Court, Suite 1032, Mail stop F-706 , Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1002/mp.12724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807157PMC
February 2018

Medical operability and inoperability drive survival in retrospective analyses comparing surgery and SBRT for early-stage lung cancer.

J Thorac Cardiovasc Surg 2018 02;155(2):810-811

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colo.

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http://dx.doi.org/10.1016/j.jtcvs.2017.09.087DOI Listing
February 2018

The 2017 American Society of Radiation Oncology (ASTRO) annual meeting: Taking a deeper dive into social media.

Adv Radiat Oncol 2018 Jul-Sep;3(3):230-233. Epub 2018 Feb 26.

Department of Radiation Oncology, Lowell General Hospital, Lowell, Massachusetts.

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http://dx.doi.org/10.1016/j.adro.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127968PMC
February 2018

Training Neurosurgery and Radiation Oncology Residents in Stereotactic Radiosurgery: Assessment Gathered from Participants in AANS and ASTRO Training Course.

World Neurosurg 2018 Jan 20;109:e669-e675. Epub 2017 Oct 20.

Department of Radiation Oncology, University of Colorado, Denver, Colorado, USA; Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S18788750173178
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http://dx.doi.org/10.1016/j.wneu.2017.10.053DOI Listing
January 2018

Hypercapnic Acidosis Regulates Mer Tyrosine Kinase Receptor Shedding and Activity.

Am J Respir Cell Mol Biol 2018 01;58(1):132-134

1 Hospital for Sick Children Toronto, Ontario, Canada and.

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http://dx.doi.org/10.1165/rcmb.2017-0316LEDOI Listing
January 2018

Radiation Dose-Volume Effects for Liver SBRT.

Int J Radiat Oncol Biol Phys 2018 Jan 6. Epub 2018 Jan 6.

Radiation Medicine Program, Princess Margaret Cancer Centre and Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ijrobp.2017.12.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095822PMC
January 2018

Prophylactic Cranial Irradiation (PCI) versus Active MRI Surveillance for Small Cell Lung Cancer: The Case for Equipoise.

J Thorac Oncol 2017 12 4;12(12):1746-1754. Epub 2017 Sep 4.

University of Colorado School of Medicine, Aurora, Colorado.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864173072
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http://dx.doi.org/10.1016/j.jtho.2017.08.016DOI Listing
December 2017

Tidal changes on CT and progression of ARDS.

Thorax 2017 11 20;72(11):981-989. Epub 2017 Jun 20.

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2016-209833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738538PMC
November 2017

National trends in radiotherapy for brain metastases at time of diagnosis of non-small cell lung cancer.

J Clin Neurosci 2017 Nov 31;45:48-53. Epub 2017 Aug 31.

Department of Radiation Oncology, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1016/j.jocn.2017.08.028DOI Listing
November 2017

Acute respiratory distress syndrome.

BMJ 2017 11 16;359:j5055. Epub 2017 Nov 16.

Departments of Anesthesia, Physiology and Interdepartmental Division of Critical Care Medicine, University of Toronto, Canada.

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http://dx.doi.org/10.1136/bmj.j5055DOI Listing
November 2017

Survival benefit of postoperative radiation in papillary meningioma: Analysis of the National Cancer Data Base.

Rep Pract Oncol Radiother 2017 Nov-Dec;22(6):495-501. Epub 2017 Oct 28.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, USA.

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http://dx.doi.org/10.1016/j.rpor.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671614PMC
October 2017

Transmission characteristics of a two dimensional antiscatter grid prototype for CBCT.

Med Phys 2017 Aug 16;44(8):3952-3964. Epub 2017 Jun 16.

Department of Radiation Oncology, University of Colorado School of Medicine, 1665 Aurora Court, Suite 1032, Mail stop, F-706, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1002/mp.12346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553722PMC
August 2017

Fifty Years of Research in ARDS. Insight into Acute Respiratory Distress Syndrome. From Models to Patients.

Am J Respir Crit Care Med 2017 07;196(1):18-28

4 Interdepartmental Division of Critical Care Medicine.

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http://dx.doi.org/10.1164/rccm.201612-2415CIDOI Listing
July 2017

Stereotactic Body Radiotherapy for Liver Metastases.

Semin Radiat Oncol 2017 07 20;27(3):240-246. Epub 2017 Feb 20.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1016/j.semradonc.2017.02.004DOI Listing
July 2017

Prophylactic cranial irradiation in small-cell lung cancer.

Lancet Oncol 2017 07;18(7):e365

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/S1470-2045(17)30378-9DOI Listing
July 2017

The Antineoplastic Activity of Photothermal Ablative Therapy with Targeted Gold Nanorods in an Orthotopic Urinary Bladder Cancer Model.

Bladder Cancer 2017 Jul 27;3(3):201-210. Epub 2017 Jul 27.

Department of Medicine, Division of Medical Oncology, University of Colorado School of Medicine, Aurora, CO, USA.

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http://dx.doi.org/10.3233/BLC-170096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545915PMC
July 2017

α-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury.

Thorax 2017 06 3;72(6):538-549. Epub 2017 Feb 3.

Physiology and Experimental Medicine, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1136/thoraxjnl-2016-209501DOI Listing
June 2017

The Head Start Effect: Will Acute and Delayed Postoperative Mortality Lead to Improved Survival with Stereotactic Body Radiation Therapy for Operable Stage I Non-Small-Cell Lung Cancer?

J Clin Oncol 2017 05 21;35(15):1749-1751. Epub 2017 Feb 21.

Chad G. Rusthoven, University of Colorado School of Medicine, Aurora, CO; David A. Palma, London Health Sciences Centre, London, Ontario, Canada; Suresh Senan, VU University Medical Center, Amsterdam, Netherlands; and Brian D. Kavanagh, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1200/JCO.2016.72.0003DOI Listing
May 2017

Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis.

J Clin Oncol 2017 Apr 23;35(10):1070-1077. Epub 2017 Jan 23.

William J. Magnuson, Nataniel H. Lester-Coll, Scott N. Gettinger, Joseph N. Contessa, James B. Yu, and Veronica L. Chiang, Yale School of Medicine, New Haven, CT; Abraham J. Wu, T. Jonathan Yang, Natalie A. Lockney, Naamit K. Gerber, and Kathryn Beal, Memorial Sloan Kettering Cancer Center, New York, NY; Arya Amini, Tejas Patil, Brian D. Kavanagh, and D. Ross Camidge, University of Colorado School of Medicine, Denver, CO; Steven E. Braunstein and Lauren C. Boreta, University of California-San Francisco, San Francisco, CA; Suresh K. Balasubramanian and Manmeet S. Ahluwalia, Cleveland Clinic Foundation, Cleveland, OH; and Niteshkumar G. Rana and Albert Attia, Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.1200/JCO.2016.69.7144DOI Listing
April 2017

The Impact of Postoperative Radiotherapy for Thymoma and Thymic Carcinoma.

J Thorac Oncol 2017 04 25;12(4):734-744. Epub 2017 Jan 25.

Department of Radiation Oncology, University of Colorado Cancer Center, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jtho.2017.01.002DOI Listing
April 2017

Reply to J.B. Aragon-Ching and D. Dalela et al.

J Clin Oncol 2017 03 12;35(8):916-917. Epub 2016 Dec 12.

Chad G. Rusthoven, Bernard L. Jones, Brian D. Kavanagh, and Thomas J. Pugh, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1200/JCO.2016.70.9220DOI Listing
March 2017

Assessing the use of 4DCT-ventilation in pre-operative surgical lung cancer evaluation.

Med Phys 2017 Jan;44(1):200-208

Department of Radiation Oncology, University of Colorado School of Medicine, 1665 Aurora Court, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1002/mp.12026DOI Listing
January 2017

Spontaneous Effort During Mechanical Ventilation: Maximal Injury With Less Positive End-Expiratory Pressure.

Crit Care Med 2016 08;44(8):e678-88

1Laboratório de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. 2Intensive Care Unit, Osaka University Hospital, Suita, Japan. 3Unidad de Cuidados Intensivos, Hospital Rebagliati, Lima, Perú. 4Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil. 5Research and Education Institute, Hospital Sirio-Libanês, São Paulo, Brazil. 6Department of Mechanical Engineering, Escola Politécnica, Universidade de São Paulo, São Paulo, Brazil. 7Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000001649DOI Listing
August 2016

Simple Factors Associated With Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy of the Thorax: A Pooled Analysis of 88 Studies.

Int J Radiat Oncol Biol Phys 2016 08 25;95(5):1357-1366. Epub 2016 Mar 25.

Department of Radiation Oncology, GRU Cancer Center/Medical College of Georgia, Georgia Regents University, Augusta, Georgia; Currently at Department of Radiation Oncology, Simon Cancer Center, Indiana University Medical School, Indianapolis, Indiana. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2016.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541363PMC
August 2016

Improved Survival With Prostate Radiation in Addition to Androgen Deprivation Therapy for Men With Newly Diagnosed Metastatic Prostate Cancer.

J Clin Oncol 2016 08 20;34(24):2835-42. Epub 2016 Jun 20.

Chad. G. Rusthoven, Bernard L. Jones, Thomas W. Flaig, E. David Crawford, Brian D. Kavanagh, and Thomas J. Pugh, University of Colorado School of Medicine, Aurora, CO; Matthew Koshy, University of Illinois at Chicago School of Medicine; Matthew Koshy, The University of Chicago School of Medicine, Chicago, IL; David J. Sher, University of Texas Southwestern, Dallas; Usama Mahmood and Brian F. Chapin University of Texas, MD Anderson Cancer Center, Houston, TX; and Ronald C. Chen University of North Carolina at Chapel Hill, Chapel Hill, NC.

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http://dx.doi.org/10.1200/JCO.2016.67.4788DOI Listing
August 2016

How Will Big Data Impact Clinical Decision Making and Precision Medicine in Radiation Therapy?

Int J Radiat Oncol Biol Phys 2016 07 6;95(3):880-884. Epub 2015 Nov 6.

Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.ijrobp.2015.10.052DOI Listing
July 2016

Survival Outcomes of Dose-Escalated External Beam Radiotherapy versus Combined Brachytherapy for Intermediate and High Risk Prostate Cancer Using the National Cancer Data Base.

J Urol 2016 May 11;195(5):1453-1458. Epub 2015 Nov 11.

Department of Radiation Oncology and Division of Urology, Department of Surgery (PM), University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2015.11.005DOI Listing
May 2016

Job shortages in anesthesia: a pro or con?

Can J Anaesth 2016 May 11;63(5):529-36. Epub 2016 Feb 11.

Department of Anesthesia, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s12630-016-0608-zDOI Listing
May 2016

Survival outcomes of radiotherapy with or without androgen-deprivation therapy for patients with intermediate-risk prostate cancer using the National Cancer Data Base.

Urol Oncol 2016 Apr 11;34(4):165.e1-9. Epub 2015 Dec 11.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1016/j.urolonc.2015.11.004DOI Listing
April 2016

Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial.

Authors:
Alain Deschamps Richard Hall Hilary Grocott C David Mazer Peter T Choi Alexis F Turgeon Etienne de Medicis Jean S Bussières Christopher Hudson Summer Syed Doug Seal Stuart Herd Jean Lambert André Denault Alain Deschamps Alan Mutch Alexis Turgeon Andre Denault Andrea Todd Angela Jerath Ashraf Fayad Barry Finnegan Blaine Kent Brent Kennedy Brian H Cuthbertson Brian Kavanagh Brian Warriner Charles MacAdams Christian Lehmann Christine Fudorow Christopher Hudson Colin McCartney Dan McIsaac Daniel Dubois David Campbell David Mazer David Neilpovitz David Rosen Davy Cheng Dennis Drapeau Derek Dillane Diem Tran Dolores Mckeen Duminda Wijeysundera Eric Jacobsohn Etienne Couture Etienne de Medicis Fahad Alam Faraj Abdallah Fiona E Ralley Frances Chung Francois Lellouche Gary Dobson Genevieve Germain George Djaiani Ian Gilron Gregory Hare Gregory Bryson Hance Clarke Heather McDonald Helen Roman-Smith Hilary Grocott Homer Yang James Douketis James Paul Jean Beaubien Jean Bussières Jeremy Pridham J N Armstrong Joel Parlow John Murkin Jonathan Gamble Kaylene Duttchen Keyvan Karkouti Kim Turner Leyla Baghirzada Linda Szabo Manoj Lalu Marcin Wasowicz Michael Bautista Michael Jacka Michael Murphy Michael Schmidt Michaël Verret Michel-Antoine Perrault Nicolas Beaudet Norman Buckley Peter Choi Peter MacDougall Philip Jones Pierre Drolet Pierre Beaulieu Ravi Taneja Rene Martin Richard Hall Ronald George Rosa Chun Sarah McMullen Scott Beattie Sonia Sampson Stephen Choi Stephen Kowalski Stuart McCluskey Summer Syed Sylvain Boet Tim Ramsay Tarit Saha Thomas Mutter Tumul Chowdhury Vishal Uppal William Mckay

Anesthesiology 2016 Apr;124(4):826-36

From the Department of Anesthesiology (A. Deschamps, A. Denault) and Department of Intensive Care Medicine (A. Denault), Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada; Department of Anesthesiology and Critical Care Medicine, Queen Elizabeth II Health Science Centre, Dalhousie University, Halifax, Canada (R.H.); Department of Anesthesiology, University of Manitoba, St. Boniface Hospital, Winnipeg, Manitoba, Canada (H.G.); Department of Anesthesia, University of Toronto, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada (C.D.M.); Department of Anesthesiology Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada (P.T.C.); Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, and Population Health and Optimal Health Practices, CHU de Québec Research Center, CHU de Québec, Université Laval, Quebec City, Quebec, Canada (A.F.T.); Department of Anesthesiology, CHU de Sherbrooke, Université de Sherbrooke, Sherbrooke, Quebec, Canada (E.d.M.); Department of Anesthesiology, Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Quebec, Canada (J.S.B.); Department of Anesthesiology, Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada (C.H.); Department of Anesthesiology, McMaster University, Hamilton, Ontario, Canada (S.S.); Department of Anesthesiology, Calgary Foothills Hospital, University of Calgary, Calgary, Alberta, Canada (D.S.); Department of Anesthesiology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada (S.H.); and Department of Social and Preventive Medicine, University of Montreal, Montreal, Quebec, Canada (J.L.).Montreal Heart Institute, Montreal, QuébecUniversity of Manitoba, Winnipeg, ManitobaUniversité Laval, Québec, QuébecPh.D., Montreal Heart Institute, Montreal, Qu

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http://dx.doi.org/10.1097/ALN.0000000000001029DOI Listing
April 2016

What do we treat when we treat ARDS?

Intensive Care Med 2016 Feb 14;42(2):284-6. Epub 2015 Dec 14.

Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1007/s00134-015-4150-1DOI Listing
February 2016

Visualizing the Propagation of Acute Lung Injury.

Anesthesiology 2016 Jan;124(1):121-31

From the Departments of Anesthesiology and Critical Care (M.C., N.M.), Radiology (Y.X., J.Z., Y.J., H.H., H.P., S.K., J.C., J.W., J.C.G., R.R.R.), and Pathology and Laboratory Medicine (C.G.D.), University of Pennsylvania, Philadelphia, Pennsylvania; and Department of Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada (B.P.K.).

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http://dx.doi.org/10.1097/ALN.0000000000000916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681653PMC
January 2016

Survival Outcomes of Whole-Pelvic Versus Prostate-Only Radiation Therapy for High-Risk Prostate Cancer Patients With Use of the National Cancer Data Base.

Int J Radiat Oncol Biol Phys 2015 Dec 18;93(5):1052-63. Epub 2015 Sep 18.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.09.006DOI Listing
December 2015