Brian F Kiesel

Brian F Kiesel

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Brian F Kiesel

Brian F Kiesel

Publications by authors named "Brian F Kiesel"

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LC-MS/MS assay for the quantitation of the ribonucleotide reductase inhibitor triapine in human plasma.

J Pharm Biomed Anal 2017 Nov 31;146:154-160. Epub 2017 Aug 31.

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, United States; Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07317085173168
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http://dx.doi.org/10.1016/j.jpba.2017.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636190PMC
November 2017

LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma.

J Pharm Biomed Anal 2017 Nov 31;146:244-250. Epub 2017 Aug 31.

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA; Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2017.08.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632222PMC
November 2017

Phase I study of veliparib in combination with gemcitabine.

Cancer Chemother Pharmacol 2017 Sep 2;80(3):631-643. Epub 2017 Aug 2.

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Hillman Research Pavilion, Room G27E, 5117 Centre Avenue, Pittsburgh, PA, 15213-1863, USA.

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http://dx.doi.org/10.1007/s00280-017-3409-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734661PMC
September 2017

LC-MS/MS assay for the simultaneous quantitation of the ATM inhibitor AZ31 and the ATR inhibitor AZD6738 in mouse plasma.

J Pharm Biomed Anal 2017 May 4;138:158-165. Epub 2017 Feb 4.

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA; Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07317085173024
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http://dx.doi.org/10.1016/j.jpba.2017.01.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357441PMC
May 2017

LC-MS/MS assay for the quantitation of the tyrosine kinase inhibitor neratinib in human plasma.

J Pharm Biomed Anal 2017 Feb 22;134:130-136. Epub 2016 Nov 22.

Cancer Therapeutics Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA; Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2016.11.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183482PMC
February 2017

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation.

Cancer Chemother Pharmacol 2016 Dec 24;78(6):1225-1235. Epub 2016 Oct 24.

Cancer Therapeutics Program, The University of Pittsburgh Cancer Institute, Hillman Cancer Center, Room G27e, 5117 Centre Ave, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1007/s00280-016-3181-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115981PMC
December 2016

Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation.

Br J Clin Pharmacol 2015 Nov 19;80(5):1097-108. Epub 2015 Sep 19.

Department of Pharmaceutical Sciences, School of Pharmacy, Pittsburgh, PA.

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http://dx.doi.org/10.1111/bcp.12723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631182PMC
November 2015

LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma.

J Pharm Biomed Anal 2013 Jul-Aug;81-82:89-98. Epub 2013 Apr 9.

Molecular Therapeutics Drug Discovery Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213-1863, USA.

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http://dx.doi.org/10.1016/j.jpba.2013.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663884PMC
December 2013