Publications by authors named "Brian D Strahl"

100Publications

Molecular mechanism of the MORC4 ATPase activation.

Nat Commun 2020 10 29;11(1):5466. Epub 2020 Oct 29.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.

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October 2020

The SAGA continues: The rise of cis- and trans-histone crosstalk pathways.

Biochim Biophys Acta Gene Regul Mech 2020 Jul 6:194600. Epub 2020 Jul 6.

Department of Biochemistry and Purdue University Center for Cancer Research, Purdue University, Hansen Life Science Research Building, 201S, University Street, West Lafayette, IN 47907; USA. Electronic address:

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July 2020

Unique and Shared Roles for Histone H3K36 Methylation States in Transcription Regulation Functions.

Cell Rep 2020 06;31(10):107751

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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June 2020

Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal.

ACS Infect Dis 2020 07 30;6(7):1719-1733. Epub 2020 May 30.

UNC HIV Cure Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.

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July 2020

The histone H4 basic patch regulates SAGA-mediated H2B deubiquitination and histone acetylation.

J Biol Chem 2020 05 3;295(19):6561-6569. Epub 2020 Apr 3.

Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599

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May 2020

Engineered Reader Proteins for Enhanced Detection of Methylated Lysine on Histones.

ACS Chem Biol 2020 01 1;15(1):103-111. Epub 2019 Nov 1.

Department of Chemistry , University of North Carolina at Chapel Hill , CB 3290, Chapel Hill , North Carolina 27599 , United States.

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January 2020

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules.

Sci Rep 2019 10 2;9(1):14226. Epub 2019 Oct 2.

Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.

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October 2019

Improved methods for the detection of histone interactions with peptide microarrays.

Sci Rep 2019 04 18;9(1):6265. Epub 2019 Apr 18.

Department of Biochemistry and Biophysics, 120 Mason Farm Rd, University of North Carolina at Chapel Hill, NC, Chapel Hill, 27599, USA.

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April 2019

Neutrophils: back in the thrombosis spotlight.

Blood 2019 05 21;133(20):2186-2197. Epub 2019 Mar 21.

Department of Medicine.

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May 2019

H3K9 Promotes Under-Replication of Pericentromeric Heterochromatin in Drosophila Salivary Gland Polytene Chromosomes.

Genes (Basel) 2019 01 29;10(2). Epub 2019 Jan 29.

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

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January 2019

Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation.

PLoS Genet 2019 01 30;15(1):e1007932. Epub 2019 Jan 30.

Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.

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January 2019

Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction.

Cell Rep 2018 12;25(12):3476-3489.e5

Department of Biochemistry & Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA. Electronic address:

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December 2018

Engineering Improved Photoswitches for the Control of Nucleocytoplasmic Distribution.

ACS Synth Biol 2018 12 29;7(12):2898-2907. Epub 2018 Nov 29.

Department of Biochemistry & Biophysics , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.

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December 2018

Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in .

Genome Res 2018 11 2;28(11):1688-1700. Epub 2018 Oct 2.

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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November 2018

Recognition of cancer mutations in histone H3K36 by epigenetic writers and readers.

Epigenetics 2018 23;13(7):683-692. Epub 2018 Aug 23.

a Department of Pharmacology , University of Colorado School of Medicine , Aurora , CO , USA.

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March 2019

PBRM1 bromodomains variably influence nucleosome interactions and cellular function.

J Biol Chem 2018 08 9;293(35):13592-13603. Epub 2018 Jul 9.

From the Department of Genetics, Curriculum in Genetics and Molecular Biology,

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August 2018

Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription.

Mol Cell 2018 06;70(6):1054-1066.e4

Department of Biochemistry & Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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June 2018

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1.

Biochemistry 2018 04 28;57(14):2140-2149. Epub 2018 Mar 28.

Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.

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April 2018

Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster.

BMC Genomics 2018 02 21;19(1):157. Epub 2018 Feb 21.

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, 27599, USA.

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February 2018

The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer.

Cell Rep 2017 Dec;21(12):3390-3397

Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA; Program in Genetics and Epigenetics, The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Electronic address:

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December 2017

Functional Redundancy of Variant and Canonical Histone H3 Lysine 9 Modification in .

Genetics 2018 01 13;208(1):229-244. Epub 2017 Nov 13.

Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, North Carolina 27599

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January 2018

A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO.

Structure 2017 10 14;25(10):1530-1539.e3. Epub 2017 Sep 14.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address:

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October 2017

Redundant Functions for Nap1 and Chz1 in H2A.Z Deposition.

Sci Rep 2017 09 7;7(1):10791. Epub 2017 Sep 7.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

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September 2017

H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity.

Cell Rep 2017 06;19(11):2371-2382

Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biochemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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June 2017

Shaping the cellular landscape with Set2/SETD2 methylation.

Cell Mol Life Sci 2017 09 6;74(18):3317-3334. Epub 2017 Apr 6.

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, 27599, USA.

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September 2017

Expanding the Reader Landscape of Histone Acylation.

Structure 2017 04;25(4):571-573

Department of Biochemistry and Biophysics, The University of North Carolina, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA. Electronic address:

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April 2017

Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity.

Elife 2017 03 27;6. Epub 2017 Mar 27.

Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, United States.

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March 2017

Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions.

Epigenetics Chromatin 2017 14;10:12. Epub 2017 Mar 14.

Department of Biochemistry and Biophysics, The University of North Carolina, Chapel Hill, NC 27599 USA.

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January 2018

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.

Cell Rep 2016 12;17(10):2724-2737

Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building Roosevelt Drive, Oxford OX3 7DQ, UK. Electronic address:

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December 2016

Direct interrogation of the role of H3K9 in metazoan heterochromatin function.

Genes Dev 2016 08 26;30(16):1866-80. Epub 2016 Aug 26.

Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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August 2016

Histone H3 and TORC1 prevent organelle dysfunction and cell death by promoting nuclear retention of HMGB proteins.

Epigenetics Chromatin 2016 17;9:34. Epub 2016 Aug 17.

Department of Pathology and Laboratory Medicine, UT Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN USA.

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August 2016

Insights into newly discovered marks and readers of epigenetic information.

Nat Chem Biol 2016 Aug;12(9):662-8

Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado, USA.

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August 2016

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.

J Biol Chem 2016 Sep 15;291(40):21283-21295. Epub 2016 Aug 15.

From the Department of Genetics, Curriculum in Genetics and Molecular Biology, the Lineberger Comprehensive Cancer Center, and the Division of Hematology and Oncology, Department of Cancer Biology, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee 37232

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September 2016

Combinatorial Histone Readout by the Dual Plant Homeodomain (PHD) Fingers of Rco1 Mediates Rpd3S Chromatin Recruitment and the Maintenance of Transcriptional Fidelity.

J Biol Chem 2016 Jul 16;291(28):14796-802. Epub 2016 May 16.

From the Curriculum in Genetics and Molecular Biology and the Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599,

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July 2016

Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation.

J Biol Chem 2016 Jun 3;291(26):13410-20. Epub 2016 May 3.

the Department of Biochemistry and Molecular Biology and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana 46202, and

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June 2016

Light-induced nuclear export reveals rapid dynamics of epigenetic modifications.

Nat Chem Biol 2016 06 18;12(6):399-401. Epub 2016 Apr 18.

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, USA.

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June 2016

The Taf14 YEATS domain is a reader of histone crotonylation.

Nat Chem Biol 2016 06 18;12(6):396-8. Epub 2016 Apr 18.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado, USA.

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June 2016

The essential role of acetyllysine binding by the YEATS domain in transcriptional regulation.

Transcription 2016 ;7(1):14-20

b Department of Biochemistry & Biophysics , The University of North Carolina School of Medicine , Chapel Hill , NC , USA.

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November 2016

Histone H3K36 methylation regulates pre-mRNA splicing in Saccharomyces cerevisiae.

RNA Biol 2016 29;13(4):412-26. Epub 2016 Jan 29.

c Department of Biology , The College of New Jersey , Ewing , NJ , USA.

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December 2016

Regulation of Methyllysine Readers through Phosphorylation.

ACS Chem Biol 2016 Mar 6;11(3):547-53. Epub 2016 Jan 6.

Department of Pharmacology, University of Colorado School of Medicine , Aurora, Colorado 80045, United States.

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March 2016

Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation.

Cell Host Microbe 2015 Dec;18(6):649-58

Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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December 2015

A course-based undergraduate research experience investigating p300 bromodomain mutations.

Biochem Mol Biol Educ 2016 Jan-Feb;44(1):68-74. Epub 2015 Nov 5.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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October 2016

Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.

Genes Dev 2015 Sep;29(17):1795-800

Department of Biochemistry and Biophysics, The University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 USA; Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, North Carolina 27599 USA; Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 USA;

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September 2015

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin.

J Biol Chem 2015 Oct 3;290(43):26088-102. Epub 2015 Sep 3.

the Center for Integrative Chemical Biology and Drug Discovery, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina 27599,

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October 2015

An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.

Cell Rep 2015 Sep 20;12(9):1400-6. Epub 2015 Aug 20.

Department of Biochemistry, University of California, Riverside, Riverside, CA 92521, USA. Electronic address:

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September 2015

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes.

J Biol Chem 2015 Sep 30;290(38):22919-30. Epub 2015 Jul 30.

From the Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045,

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September 2015

An Interactive Database for the Assessment of Histone Antibody Specificity.

Mol Cell 2015 Aug 23;59(3):502-11. Epub 2015 Jul 23.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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August 2015

Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX.

Chem Biol 2015 Jul 25;22(7):849-61. Epub 2015 Jun 25.

Department of Chemistry & Institutes of Biomedical Sciences, Fudan University, Shanghai 20032, China; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Program in Molecular & Cellular Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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July 2015

From histones to ribosomes: a chromatin regulator tangoes with translation.

Cancer Discov 2015 Mar;5(3):228-30

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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March 2015

Interrogating the function of metazoan histones using engineered gene clusters.

Dev Cell 2015 Feb;32(3):373-86

Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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February 2015

Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.

ACS Chem Biol 2015 Apr 28;10(4):1072-81. Epub 2015 Jan 28.

†Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

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April 2015

Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1.

Structure 2015 Feb 8;23(2):312-21. Epub 2015 Jan 8.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address:

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February 2015

Product binding enforces the genomic specificity of a yeast polycomb repressive complex.

Cell 2015 Jan 18;160(1-2):204-18. Epub 2014 Dec 18.

Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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January 2015

A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.

Mol Cell Proteomics 2014 Nov 6;13(11):2883-95. Epub 2014 Aug 6.

From the ‡Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205; §Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205;

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November 2014

SET-ting the stage for DNA repair.

Nat Struct Mol Biol 2014 Aug;21(8):655-7

1] Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, North Carolina, USA. [2] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina, USA.

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August 2014

Catalysis-dependent stabilization of Bre1 fine-tunes histone H2B ubiquitylation to regulate gene transcription.

Genes Dev 2014 Aug;28(15):1647-52

Curriculum in Genetics and Molecular Biology, Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA

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August 2014

Chromatin biochemistry enters the next generation of code 'seq-ing'.

Nat Methods 2014 Aug;11(8):799-800

1] Department of Biochemistry &Biophysics, University of North Carolina at Chapel Hill, North Carolina, USA [2] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina, USA.

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August 2014

An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair.

Nat Commun 2014 Jun 9;5:3965. Epub 2014 Jun 9.

1] Department of Biochemistry and Biophysics, School of Medicine, UNC-Chapel Hill, North Carolina, USA [2] Lineberger Comprehensive Cancer Center, School of Medicine, UNC-Chapel Hill, North Carolina 27599, USA.

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June 2014

A histone methylation network regulates transgenerational epigenetic memory in C. elegans.

Cell Rep 2014 Apr 27;7(1):113-26. Epub 2014 Mar 27.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Division of Newborn Medicine, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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April 2014

Hitting the 'mark': interpreting lysine methylation in the context of active transcription.

Biochim Biophys Acta 2014 Dec 12;1839(12):1353-61. Epub 2014 Mar 12.

Curriculum in Genetics and Molecular Biology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA. Electronic address:

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December 2014

Interpreting the language of histone and DNA modifications.

Biochim Biophys Acta 2014 Aug 12;1839(8):627-43. Epub 2014 Mar 12.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

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August 2014

The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.

Cell Rep 2014 Jan 9;6(2):325-35. Epub 2014 Jan 9.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Molecular Biology Program, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address:

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January 2014

A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation.

Nucleic Acids Res 2014 Jan 25;42(2):870-81. Epub 2013 Oct 25.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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January 2014

Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue.

Proc Natl Acad Sci U S A 2013 Sep 3;110(38):15277-82. Epub 2013 Sep 3.

Gene Center Munich and Department of Biochemistry, Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

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September 2013

Stress-free with Rpd3: a unique chromatin complex mediates the response to oxidative stress.

Mol Cell Biol 2013 Oct 12;33(19):3726-7. Epub 2013 Aug 12.

Curriculum in Genetics and Molecular Biology.

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October 2013

Molecular basis for chromatin binding and regulation of MLL5.

Proc Natl Acad Sci U S A 2013 Jul 24;110(28):11296-301. Epub 2013 Jun 24.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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July 2013

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.

Nature 2013 Jun 1;498(7454):385-9. Epub 2013 May 1.

Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, California 90095, USA.

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June 2013

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.

Mol Cell 2013 Feb 27;49(3):571-82. Epub 2012 Dec 27.

UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.

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February 2013

Broad ranges of affinity and specificity of anti-histone antibodies revealed by a quantitative peptide immunoprecipitation assay.

J Mol Biol 2012 Dec 2;424(5):391-9. Epub 2012 Oct 2.

Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.

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December 2012

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.

Nat Struct Mol Biol 2012 Nov 30;19(11):1155-60. Epub 2012 Sep 30.

Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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November 2012