Publications by authors named "Brian D Bennett"

28Publications

Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes.

Sci Adv 2020 Nov 20;6(47). Epub 2020 Nov 20.

Chromatin and Gene Expression Section, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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November 2020

Single-cell analyses identify dysfunctional CD16 CD8 T cells in smokers.

Cell Rep Med 2020 Jul;1(4)

Environmental Epigenomics and Disease Group, Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, 27709.

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July 2020

Cancer-specific mutation of GATA3 disrupts the transcriptional regulatory network governed by Estrogen Receptor alpha, FOXA1 and GATA3.

Nucleic Acids Res 2020 05;48(9):4756-4768

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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May 2020

Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity.

J Biol Chem 2020 01 5;295(5):1271-1287. Epub 2019 Dec 5.

Chromatin and Gene Expression Section, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina 27709

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January 2020

NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region.

Nat Commun 2019 07 11;10(1):3072. Epub 2019 Jul 11.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, NC, 27709, USA.

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July 2019

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

J Allergy Clin Immunol 2019 06 21;143(6):2062-2074. Epub 2018 Dec 21.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC. Electronic address:

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June 2019

Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells.

Sci Total Environ 2019 Feb 20;651(Pt 1):1038-1046. Epub 2018 Sep 20.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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February 2019

Revealing a human p53 universe.

Nucleic Acids Res 2018 09;46(16):8153-8167

Genome Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences/National Institutes of Health, Research Triangle Park, NC 27709, USA.

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September 2018

Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver.

Sci Rep 2018 07 4;8(1):10138. Epub 2018 Jul 4.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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July 2018

Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression.

Environ Health Perspect 2018 04 27;126(4):047015. Epub 2018 Apr 27.

Environmental Epigenomics and Disease Group, Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA.

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April 2018

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network.

Nat Commun 2018 03 13;9(1):1059. Epub 2018 Mar 13.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, 27709, USA.

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March 2018

Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation.

Nucleic Acids Res 2017 Dec;45(22):12723-12738

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, RTP, NC 27709, USA.

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December 2017

goSTAG: gene ontology subtrees to tag and annotate genes within a set.

Source Code Biol Med 2017 13;12. Epub 2017 Apr 13.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, 27709 NC USA.

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April 2017

ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data.

Nucleic Acids Res 2017 Jun;45(10):5678-5690

Office of Scientific Computing, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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June 2017

Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes.

PLoS One 2016 9;11(12):e0166486. Epub 2016 Dec 9.

Environmental Genomics Group, Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, United States of America.

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July 2017

CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State.

Stem Cell Reports 2016 11 13;7(5):897-910. Epub 2016 Oct 13.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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November 2016

Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters.

PLoS Genet 2016 08 3;12(8):e1006224. Epub 2016 Aug 3.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.

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August 2016

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma.

Genes Dev 2016 06;30(12):1440-53

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA;

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June 2016

A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.

Stem Cell Reports 2016 05 3;6(5):704-716. Epub 2016 Mar 3.

Department of Molecular Biology, Center for Regenerative Medicine and Cancer Center, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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May 2016

LIN28A Modulates Splicing and Gene Expression Programs in Breast Cancer Cells.

Mol Cell Biol 2015 Sep 6;35(18):3225-43. Epub 2015 Jul 6.

Chromatin and Gene Expression Section, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA

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September 2015

Expression of ORAII, a plasma membrane resident subunit of the CRAC channel, in rodent and non-rodent species.

J Histochem Cytochem 2014 Dec 23;62(12):864-78. Epub 2014 Sep 23.

Departments of Pathology (RG, EGV, JP, EP, MQ), Amgen, Inc. Thousand Oaks, CaliforniaTherapeutic Discovery (FFL, VB), Amgen, Inc. Thousand Oaks, CaliforniaDiscovery Toxicology (HJM), Amgen, Inc. Thousand Oaks, CaliforniaInflammation Research (BDB, DHF), Amgen, Inc. Thousand Oaks, California

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December 2014

Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells.

Cell Rep 2013 Nov 14;5(4):933-40. Epub 2013 Nov 14.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA; Program in Molecular Cancer Biology, Duke University, Durham, NC 27710, USA.

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November 2013

A predictive framework for integrating disparate genomic data types using sample-specific gene set enrichment analysis and multi-task learning.

PLoS One 2012 13;7(9):e44635. Epub 2012 Sep 13.

Department of Statistical Science, Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America.

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March 2013