Brian Cox

Brian Cox

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Brian Cox

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Unbiased data analytic strategies to improve biomarker discovery in precision medicine.

Drug Discov Today 2019 Sep 31;24(9):1735-1748. Epub 2019 May 31.

Reproduction and Development Platform, Department of Physiology, University of Toronto, Medical Sciences Building, Room 3360, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2019.05.018DOI Listing
September 2019

Accurate ethnicity prediction from placental DNA methylation data.

Epigenetics Chromatin 2019 Aug 9;12(1):51. Epub 2019 Aug 9.

Department of Medical Genetics, University of British Columbia, C201-4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.

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http://dx.doi.org/10.1186/s13072-019-0296-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688210PMC
August 2019

Both "canonical" and "immunological" preeclampsia subtypes demonstrate changes in placental immune cell composition.

Placenta 2019 Aug 27;83:53-56. Epub 2019 Jun 27.

Department of Physiology, University of Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2019.06.384DOI Listing
August 2019

Addressing the Opioid Crisis: Medical Student Instruction in Opiate Drug Pharmacology and Pain Management.

J Pharmacol Exp Ther 2019 Jul 18. Epub 2019 Jul 18.

Uniformed Services University.

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http://dx.doi.org/10.1124/jpet.119.257329DOI Listing
July 2019

Trends in myeloma incidence, mortality and survival in New Zealand (1985-2016).

Cancer Epidemiol 2019 Jun 25;60:55-59. Epub 2019 Mar 25.

Department of Pathology, Dunedin School of Medicine, University of Otago, PO Box 56, Dunedin 9054, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2019.03.006DOI Listing
June 2019

Recurrent Placental Transcriptional Profile With a Different Histological and Clinical Presentation: A Case Report.

Pediatr Dev Pathol 2019 Jun 7:1093526619852871. Epub 2019 Jun 7.

4 Department of Pathology and Laboratory Medicine, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1177/1093526619852871DOI Listing
June 2019

Code of Rights and bowel screening.

N Z Med J 2019 Jun 21;132(1497):78-79. Epub 2019 Jun 21.

Senior Research Fellow, Hugh Adam Cancer Epidemiology Unit, Dunedin School of Medicine, University of Otago, Dunedin.

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June 2019

First Clinical Application of Low-Cost OCT.

Transl Vis Sci Technol 2019 May 28;8(3):61. Epub 2019 Jun 28.

Department of Biomedical Engineering, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1167/tvst.8.3.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602122PMC
May 2019

Understanding the Alkylation of a Phenol by 1-(3-Chloropropyl)pyrrolidine: Evidence for the Intermediacy of an Azetidinium Ion.

J Org Chem 2019 Apr 13;84(8):4754-4762. Epub 2018 Nov 13.

Early Product Development, Pharmaceutical Sciences, IMED Biotech Unit , AstraZeneca , Silk Road Business Park , Macclesfield , SK10 2NA , United Kingdom.

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http://dx.doi.org/10.1021/acs.joc.8b02458DOI Listing
April 2019

The discovery of novel predictive biomarkers and early-stage pathophysiology for the transition from gestational diabetes to type 2 diabetes.

Diabetologia 2019 04 15;62(4):687-703. Epub 2019 Jan 15.

Endocrine and Diabetes Platform, Department of Physiology, University of Toronto, Medical Sciences Building, Room 3352, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.

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http://dx.doi.org/10.1007/s00125-018-4800-2DOI Listing
April 2019

Correction to: The discovery of novel predictive biomarkers and early-stage pathophysiology for the transition from gestational diabetes to type 2 diabetes.

Diabetologia 2019 04;62(4):730-731

Endocrine and Diabetes Platform, Department of Physiology, University of Toronto, Medical Sciences Building, Room 3352, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.

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http://dx.doi.org/10.1007/s00125-019-4827-zDOI Listing
April 2019

Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia.

Clin Epigenetics 2018 2;10:28. Epub 2018 Mar 2.

1Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, ON Canada.

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http://dx.doi.org/10.1186/s13148-018-0463-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833042PMC
February 2019

A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling.

Cell 2019 Feb 24;176(4):913-927.e18. Epub 2019 Jan 24.

Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON M5S 3E5, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada; Toronto General Hospital Research Institute, Toronto, ON M5G 2C4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.11.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456036PMC
February 2019

Placental transcriptional and histologic subtypes of normotensive fetal growth restriction are comparable to preeclampsia.

Am J Obstet Gynecol 2019 Jan 9;220(1):110.e1-110.e21. Epub 2018 Oct 9.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029378183087
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http://dx.doi.org/10.1016/j.ajog.2018.10.003DOI Listing
January 2019

The Synthesis of Waltherione F and Its Analogues with Modifications at the 2- and 3-Positions as Potential Antitrypanosomal Agents.

Chemistry 2019 Jan 20;25(5):1286-1292. Epub 2018 Dec 20.

School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK.

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http://doi.wiley.com/10.1002/chem.201804061
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http://dx.doi.org/10.1002/chem.201804061DOI Listing
January 2019

Mitochondrial and chloroplast genomes provide insights into the evolutionary origins of quinoa (Chenopodium quinoa Willd.).

Sci Rep 2019 Jan 17;9(1):185. Epub 2019 Jan 17.

Brigham Young University, Department of Plant and Wildlife Sciences, College of Life Sciences, Provo, Utah 84602, USA.

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http://dx.doi.org/10.1038/s41598-018-36693-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336861PMC
January 2019

Cellular systems biology identifies dynamic trophoblast populations in early human placentas.

Placenta 2019 Jan 11;76:10-18. Epub 2019 Jan 11.

Department of Physiology, University of Toronto, Toronto, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2018.12.012DOI Listing
January 2019

Preface.

Prog Med Chem 2018;57(1):ix-x

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http://dx.doi.org/10.1016/S0079-6468(18)30010-9DOI Listing
December 2018

The clinical heterogeneity of preeclampsia is related to both placental gene expression and placental histopathology.

Am J Obstet Gynecol 2018 12 29;219(6):604.e1-604.e25. Epub 2018 Sep 29.

Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Interdisciplinary School of Health Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2018.09.036DOI Listing
December 2018

Targeting histone deacetylation for recovery of maternal deprivation-induced changes in BDNF and AKAP150 expression in the VTA.

Exp Neurol 2018 11 10;309:160-168. Epub 2018 Aug 10.

Uniformed Services University of the Health Sciences, Department of Pharmacology, Bethesda, MD 20814, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139260PMC
November 2018

Response to Smith et al.

J Am Soc Cytopathol 2018 Nov - Dec;7(6):338. Epub 2018 Oct 3.

Department of Preventive and Social Medicine, Hugh Adam Cancer Epidemiology Unit, University of Otago, Otago, New Zealand.

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http://dx.doi.org/10.1016/j.jasc.2018.09.003DOI Listing
October 2018

HPV screening, invasive cervical cancer and screening policy in Australia.

J Am Soc Cytopathol 2018 Nov - Dec;7(6):292-299. Epub 2018 Jul 19.

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1016/j.jasc.2018.07.003DOI Listing
July 2018

Global Versus Momentary Osteoarthritis Pain and Emotional Distress: Emotional Intelligence as Moderator.

Ann Behav Med 2018 07;52(8):713-723

Program in Public Health, Department of Family, Population, and Preventive Medicine, Stony Brook University, Stony Brook, NY, USA.

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http://dx.doi.org/10.1093/abm/kax044DOI Listing
July 2018

Recommendations for cervical cancer prevention and control in Ghana: public education and human papillomavirus vaccination.

Ghana Med J 2018 Jun;52(2):94-102

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, University of Otago, Dunedin, Otago, New Zealand.

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https://www.ajol.info/index.php/gmj/article/view/174670
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http://dx.doi.org/10.4314/gmj.v52i2.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326540PMC
June 2018

Development of a systems-based in situ multiplex biomarker screening approach for the assessment of immunopathology and neural tissue plasticity in male rats after traumatic brain injury.

J Neurosci Res 2018 04 2;96(4):487-500. Epub 2017 May 2.

Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, Maryland.

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http://dx.doi.org/10.1002/jnr.24054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668208PMC
April 2018

Uncertain Environmental Footprint of Current and Future Battery Electric Vehicles.

Environ Sci Technol 2018 04 30;52(8):4989-4995. Epub 2018 Mar 30.

PBL Netherlands Environmental Assessment Agency , The Hague 2594 , Netherlands.

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http://dx.doi.org/10.1021/acs.est.8b00261DOI Listing
April 2018

Author Correction: The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.

Sci Rep 2018 Apr 5;8(1):5762. Epub 2018 Apr 5.

Laboratory of Transgenic Models of Diseases, Division, BIOCEV, Institute of Molecular Genetics of the CAS, v.v.i., Vestec, Czech Republic.

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http://dx.doi.org/10.1038/s41598-018-22650-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886979PMC
April 2018

Design and implementation of a low-cost, portable OCT system.

Biomed Opt Express 2018 Mar 20;9(3):1232-1243. Epub 2018 Feb 20.

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1364/BOE.9.001232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846526PMC
March 2018

The life of [PSI].

Curr Genet 2018 Feb 26;64(1):1-8. Epub 2017 Jun 26.

Kent Fungal Group, School of Biosciences, University of Kent, Canterbury, Kent, CT2 7NJ, UK.

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http://dx.doi.org/10.1007/s00294-017-0714-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778180PMC
February 2018

Characteristics of Women Diagnosed with Invasive Cervical Cancer in Ghana

Asian Pac J Cancer Prev 2018 Feb 26;19(2):357-363. Epub 2018 Feb 26.

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand. Email:

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http://dx.doi.org/10.22034/APJCP.2018.19.2.357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980920PMC
February 2018

Mining DNA methylation alterations towards a classification of placental pathologies.

Hum Mol Genet 2018 01;27(1):135-146

BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.

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http://dx.doi.org/10.1093/hmg/ddx391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886226PMC
January 2018

WWL70 protects against chronic constriction injury-induced neuropathic pain in mice by cannabinoid receptor-independent mechanisms.

J Neuroinflammation 2018 Jan 8;15(1). Epub 2018 Jan 8.

Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.

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http://dx.doi.org/10.1186/s12974-017-1045-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759843PMC
January 2018

Cervical Cancer in the Greater Accra and Ashanti Regions of Ghana.

J Glob Oncol 2017 Dec 28;3(6):782-790. Epub 2016 Oct 28.

Yvonne Nartey, Philip C. Hill, and Brian Cox, University of Otago, Dunedin, New Zealand; Kwabena Amo-Antwi, Komfo Anokye Teaching Hospital, Kumasi; Kofi M. Nyarko, Ghana Health Service; and Joel Yarney, Korle Bu Teaching Hospital, Accra, Ghana.

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http://dx.doi.org/10.1200/JGO.2016.005744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735962PMC
December 2017

Cellular analysis of trophoblast and placenta.

Placenta 2017 Nov 30;59 Suppl 1:S2-S7. Epub 2016 Nov 30.

Department of Physiology, University of Toronto, Toronto, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2016.11.015DOI Listing
November 2017

Factors Contributing to the Low Survival Among Women With a Diagnosis of Invasive Cervical Cancer in Ghana.

Int J Gynecol Cancer 2017 11;27(9):1926-1934

*Hugh Adam Cancer Epidemiology Unit and †Centre for International Health, University of Otago, Dunedin, New Zealand; and ‡Department of Obstetrics and Gynecology, Komfo Anokye Teaching Hospital, Kumasi; and §Disease Control and Prevention Department, Ghana Health Service; and ∥National Centre for Radiotherapy and Nuclear Medicine, Korle Bu Teaching Hospital, Accra, Ghana.

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http://dx.doi.org/10.1097/IGC.0000000000001088DOI Listing
November 2017

Zika Virus Causes Persistent Infection in Porcine Conceptuses and may Impair Health in Offspring.

EBioMedicine 2017 Nov 21;25:73-86. Epub 2017 Sep 21.

Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac), University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada; Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; School of Public Health, University of Saskatchewan, Saskatoon, SK, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704061PMC
November 2017

Corrigendum to "Zika Virus Causes Persistent Infection in Porcine Conceptuses and May Impair Health in Offspring".

EBioMedicine 2017 11 21;25:187. Epub 2017 Oct 21.

Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac), University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada; Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada; School of Public Health, University of Saskatchewan, Saskatoon, SK, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704060PMC
November 2017

Associations between imprinted gene expression in the placenta, human fetal growth and preeclampsia.

Biol Lett 2017 11;13(11)

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1098/rsbl.2017.0643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719389PMC
November 2017

Mass Spectrometric Imaging of Ceramide Biomarkers Tracks Therapeutic Response in Traumatic Brain Injury.

ACS Chem Neurosci 2017 10 14;8(10):2266-2274. Epub 2017 Aug 14.

Structural Biology Unit, Integrative Neuroscience Branch, NIH/NIDA-IRP , Baltimore, Maryland 21224, United States.

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http://dx.doi.org/10.1021/acschemneuro.7b00189DOI Listing
October 2017

Gene markers of normal villous maturation and their expression in placentas with maturational pathology.

Placenta 2017 Oct 12;58:52-59. Epub 2017 Aug 12.

Department of Physiology, University of Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2017.08.005DOI Listing
October 2017

Functional Enterospheres Derived In Vitro from Human Pluripotent Stem Cells.

Stem Cell Reports 2017 09 31;9(3):897-912. Epub 2017 Aug 31.

McMaster Stem Cell and Cancer Research Institute, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8N 3Z5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599260PMC
September 2017

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.

Sci Rep 2017 08 24;7(1):9322. Epub 2017 Aug 24.

Laboratory of Transgenic Models of Diseases, Division, BIOCEV, Institute of Molecular Genetics of the CAS, v.v.i., Vestec, Czech Republic.

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http://dx.doi.org/10.1038/s41598-017-09490-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570896PMC
August 2017

Racial/ethnic differences in sleep quality among older adults with osteoarthritis.

Sleep Health 2017 06 22;3(3):163-169. Epub 2017 Apr 22.

Department of Preventive Medicine, Program in Public Health, Stony Brook University, Stony Brook, NY 11794.

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http://dx.doi.org/10.1016/j.sleh.2017.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501090PMC
June 2017

Breast Cancer Screening in a Resource Poor Country: Ultrasound Versus Mammography.

Ghana Med J 2017 06;51(2):98-99

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, University of Otago, P. O. Box 56 Dunedin, New Zealand.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611902PMC
June 2017

Overexpression of Trophoblast Stem Cell-Enriched MicroRNAs Promotes Trophoblast Fate in Embryonic Stem Cells.

Cell Rep 2017 05;19(6):1101-1109

Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173053
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http://dx.doi.org/10.1016/j.celrep.2017.04.040DOI Listing
May 2017

Over-expression of the molecular chaperone Hsp104 in Saccharomyces cerevisiae results in the malpartition of [PSI ] propagons.

Mol Microbiol 2017 04 21;104(1):125-143. Epub 2017 Feb 21.

Kent Fungal Group, School of Biosciences, University of Kent, Canterbury, Kent, NJ CT2 7, UK.

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http://dx.doi.org/10.1111/mmi.13617DOI Listing
April 2017

The renewal of the National Cervical Screening Program.

Authors:
Brian Cox

Med J Aust 2017 04;206(6):274

University of Otago, Dunedin, New Zealand

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http://dx.doi.org/10.5694/mja16.01228DOI Listing
April 2017

Oral cancer risk factors in New Zealand.

N Z Med J 2017 Mar 3;130(1451):30-38. Epub 2017 Mar 3.

Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin.

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March 2017

Response to Sarfati et al.

Authors:
Brian Cox

N Z Med J 2016 Dec 2;129(1446):114-115. Epub 2016 Dec 2.

Cancer Screening and Cancer Control, Hugh Adam Cancer Epidemiology Unit, Dunedin School of Medicine, University of Otago, Dunedin.

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December 2016

Magnetic resonance neurography in the management of peripheral trigeminal neuropathy: experience in a tertiary care centre.

Eur Radiol 2016 Oct 21;26(10):3392-400. Epub 2016 Jan 21.

Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9178, USA.

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http://dx.doi.org/10.1007/s00330-015-4182-5DOI Listing
October 2016

Mass spectrometry imaging of rat brain lipid profile changes over time following traumatic brain injury.

J Neurosci Methods 2016 10 10;272:19-32. Epub 2016 Feb 10.

Structural Biology Unit, Integrative Neuroscience Branch, NIH/NIDA-IRP, Baltimore, MD 21224, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01650270160005
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http://dx.doi.org/10.1016/j.jneumeth.2016.02.004DOI Listing
October 2016

[PSI(+)] turns 50.

Prion 2015 ;9(5):318-32

a Kent Fungal Group; School of Biosciences; University of Kent ; Canterbury , Kent , UK.

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http://dx.doi.org/10.1080/19336896.2015.1111508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964859PMC
September 2016

Morphine-induced synaptic plasticity in the VTA is reversed by HDAC inhibition.

J Neurophysiol 2016 09 15;116(3):1093-103. Epub 2016 Jun 15.

Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, Maryland

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http://dx.doi.org/10.1152/jn.00238.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013166PMC
September 2016

A Predictive Metabolic Signature for the Transition From Gestational Diabetes Mellitus to Type 2 Diabetes.

Diabetes 2016 09 23;65(9):2529-39. Epub 2016 Jun 23.

Department of Medicine, University of Toronto, Ontario, Canada Department of Physiology, University of Toronto, Ontario, Canada

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http://dx.doi.org/10.2337/db15-1720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001181PMC
September 2016

Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human Preeclampsia.

Hypertension 2016 07 9;68(1):137-47. Epub 2016 May 9.

From the Department of Physiology (K.L., J.C.K., B.J.C.) and Department of Obstetrics and Gynaecology, (J.C.K., B.J.C.), University of Toronto, Toronto, Ontario, Canada; and Department of Cellular and Molecular Medicine (S.J.B., S.A.B.), Department of Pathology and Laboratory Medicine (D.G.), and Interdisciplinary School of Health Sciences (S.A.B.), University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07293DOI Listing
July 2016

Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.

Pharmacol Rev 2016 Apr 8;68(2):419-57. Epub 2016 Mar 8.

Torrey Pines Institute for Molecular Studies, Port St. Lucie, Florida (L.T.); Departments of Anesthesiology, and Neuroscience, Washington University School of Medicine, St. Louis, Missouri (M.R.B.); Section of Pharmacology, Department of Medical Science, and National Institute of Neurosciences, University of Ferrara, Ferrara, Italy (G.C.); Professor of Pharmacology & Neuroscience, Uniformed Services University, Bethesda, Maryland (B.M.C.); and Astraea Therapeutics, LLC, Mountain View, California (N.T.Z.).

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http://dx.doi.org/10.1124/pr.114.009209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813427PMC
April 2016

Rapid Elevation in CMPF May Act As a Tipping Point in Diabetes Development.

Cell Rep 2016 Mar 17;14(12):2889-900. Epub 2016 Mar 17.

Department of Physiology, University of Toronto, 1 King's College Circle, Medical Sciences Building, Room 3352, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.079DOI Listing
March 2016

The proposed change to primary HPV screening in New Zealand: reasons for caution.

N Z Med J 2016 Mar 11;129(1431):18-22. Epub 2016 Mar 11.

Southern Community Laboratories, Plunket House, 472 George Street, Dunedin 9016, New Zealand.

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March 2016

Cells as strain-cued automata.

J Mech Phys Solids 2016 Feb 2;87:177-226. Epub 2015 Dec 2.

Center for Craniofacial Molecular Biology, Ostrow School of Dentistry of USC, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/j.jmps.2015.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550492PMC
February 2016

Flexible sigmoidoscopy is the best approach for a national bowel screening programme.

Authors:
Brian Cox

N Z Med J 2016 Feb 19;129(1430):14-7. Epub 2016 Feb 19.

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, University of Otago, PO Box 913, Dunedin.

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February 2016

Changing causes of heart valve disease mortality in New Zealand from 1988 to 2007.

N Z Med J 2016 Jan 8;129(1428):56-65. Epub 2016 Jan 8.

Department of Cardiology, Dunedin Hospital, 201 Great King Street, Dunedin 9016, New Zealand.

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January 2016

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

Genes Dev 2015 Dec 19;29(23):2435-48. Epub 2015 Nov 19.

Epigenetics Programme, The Babraham Institute, Cambridge CB22 3AT, United Kingdom; Centre for Trophoblast Research, University of Cambridge, Cambridge CB2 3EG, United Kingdom;

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http://dx.doi.org/10.1101/gad.268821.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691948PMC
December 2015

Health conditions in a cohort of New Zealand Vietnam veterans: hospital admissions between 1988 and 2009.

BMJ Open 2015 Dec 9;5(12):e008409. Epub 2015 Dec 9.

Department of Oral Diagnostic and Surgical Sciences, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1136/bmjopen-2015-008409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679881PMC
December 2015

Can the research community respond adequately to the health risks of vaping?

Authors:
Brian Cox

Addiction 2015 Nov;110(11):1708-9

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1111/add.13085DOI Listing
November 2015

Letter by Coffey et al Regarding Article, "Temporal Trends in the Incidence and Prognosis of Aortic Stenosis: A Nationwide Study of the Swedish Population".

Circulation 2015 Nov;132(20):e239

Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.017209DOI Listing
November 2015

Mu opioid receptor activation enhances regulator of G protein signaling 4 association with the mu opioid receptor/G protein complex in a GTP-dependent manner.

J Neurochem 2015 Oct 16;135(1):76-87. Epub 2015 Jul 16.

Department of Pharmacology, The Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.

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http://doi.wiley.com/10.1111/jnc.13222
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034817PMC
http://dx.doi.org/10.1111/jnc.13222DOI Listing
October 2015

Placental transcriptome in development and pathology: expression, function, and methods of analysis.

Am J Obstet Gynecol 2015 Oct;213(4 Suppl):S138-51

Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ajog.2015.07.046DOI Listing
October 2015

Histone Deacetylase Inhibition Rescues Maternal Deprivation-Induced GABAergic Metaplasticity through Restoration of AKAP Signaling.

Neuron 2015 Jun;86(5):1240-52

Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273150043
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http://dx.doi.org/10.1016/j.neuron.2015.05.024DOI Listing
June 2015

Challenges for opioid receptor nomenclature: IUPHAR Review 9.

Br J Pharmacol 2015 Jan 1;172(2):317-23. Epub 2014 Jul 1.

Department of Pharmacology, Uniformed Services University, Bethesda, MD, USA.

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http://doi.wiley.com/10.1111/bph.12612
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http://dx.doi.org/10.1111/bph.12612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292949PMC
January 2015

Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα.

Nat Commun 2015 Jan 19;6:6018. Epub 2015 Jan 19.

1] Department of Physiology, University of Toronto, 1 King's College Cir., Toronto, Ontario, Canada M5S1A8 [2] Department of Medicine, University of Toronto, 1 King's College Cir., Toronto, Ontario, Canada M5S1A8 [3] Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, 200 Elizabeth St, Toronto, Ontario, Canada M5G2C4 [4] Heart &Stroke Richard Lewar Centre of Excellence, University of Toronto, 1 King's College Cir., Toronto, Ontario, Canada M5S1A8.

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http://dx.doi.org/10.1038/ncomms7018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661059PMC
January 2015

Projected costs of colorectal cancer treatment in New Zealand in the absence of population screening.

N Z Med J 2015 Jan 30;128(1408):72-85. Epub 2015 Jan 30.

Department of Population Health, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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January 2015

Are New Zealand's cancer services second best?

Authors:
Brian Cox

N Z Med J 2014 Dec 19;127(1407):10-3. Epub 2014 Dec 19.

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, PO Box 913, Dunedin, New Zealand.

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December 2014

Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.

J Am Heart Assoc 2014 Oct 20;3(5):e001018. Epub 2014 Oct 20.

Department of Physiology, University of Toronto, Ontario, Canada (D.Y.W., C.A., J.Y.L., P.S., N.B., S.S., P.H.B., B.C., X.Y.W., P.P.L., A.O.G.) Faculty of Medicine and Institute of Medical Science, University of Toronto, Ontario, Canada (S.E.R., F.D., K.N., P.H.B., X.Y.W., P.P.L., A.O.G.).

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http://dx.doi.org/10.1161/JAHA.114.001018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323785PMC
October 2014

Bioinformatic approach to the genetics of preeclampsia.

Authors:
Brian Cox

Obstet Gynecol 2014 Sep;124(3):633

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/AOG.0000000000000436DOI Listing
September 2014

Zygotic Porcn paternal allele deletion in mice to model human focal dermal hypoplasia.

PLoS One 2013 1;8(11):e79139. Epub 2013 Nov 1.

Program in Developmental and Stem Cell Biology, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada ; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079139PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815152PMC
August 2014

The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists.

Bioorg Med Chem Lett 2014 Aug 14;24(15):3285-90. Epub 2014 Jun 14.

Novartis Institutes for BioMedical Research, Horsham Research Centre, Wimblehurst Road, Horsham, West Sussex RH12 5AB, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X140063
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http://dx.doi.org/10.1016/j.bmcl.2014.06.011DOI Listing
August 2014

Tensile testing of materials at high temperatures above 1700 °C with in situ synchrotron X-ray micro-tomography.

Rev Sci Instrum 2014 Aug;85(8):083702

Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1063/1.4892437DOI Listing
August 2014

The prevalence, incidence, progression, and risks of aortic valve sclerosis: a systematic review and meta-analysis.

J Am Coll Cardiol 2014 Jul 7;63(25 Pt A):2852-61. Epub 2014 May 7.

Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097140221
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http://dx.doi.org/10.1016/j.jacc.2014.04.018DOI Listing
July 2014

Gestational hypertension and preeclampsia: are they the same disease?

J Obstet Gynaecol Can 2014 Jul;36(7):642-647

Maternal-Fetal Medicine Division, Department of Obstetrics and Gynaecology at Mount Sinai Hospital, University of Toronto, Toronto ON.

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https://linkinghub.elsevier.com/retrieve/pii/S17012163153054
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http://dx.doi.org/10.1016/S1701-2163(15)30545-4DOI Listing
July 2014

Identification of novel IP receptor agonists using historical ligand biased chemical arrays.

Bioorg Med Chem Lett 2014 May 5;24(10):2247-50. Epub 2014 Apr 5.

Novartis Institutes for BioMedical Research, Wimblehurst Road, Horsham, West Sussex RH12 5AB, UK.

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http://dx.doi.org/10.1016/j.bmcl.2014.03.089DOI Listing
May 2014

Epidemic of non-hodgkin lymphoma in new zealand remains unexplained.

J Cancer Epidemiol 2014 1;2014:315378. Epub 2014 Apr 1.

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.

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http://dx.doi.org/10.1155/2014/315378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995303PMC
May 2014

Individual risk of cutaneous melanoma in New Zealand: developing a clinical prediction aid.

BMC Cancer 2014 May 22;14:359. Epub 2014 May 22.

Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, P,O, Box 56, Dunedin 9054, New Zealand.

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http://dx.doi.org/10.1186/1471-2407-14-359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038363PMC
May 2014

Lack of progress in valvular heart disease in the pre-transcatheter aortic valve replacement era: increasing deaths and minimal change in mortality rate over the past three decades.

Am Heart J 2014 Apr 14;167(4):562-567.e2. Epub 2014 Jan 14.

Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1016/j.ahj.2013.12.030DOI Listing
April 2014

The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists.

Bioorg Med Chem Lett 2014 Jan 4;24(1):72-6. Epub 2013 Dec 4.

Novartis Institutes for BioMedical Research, Horsham Research Centre, Wimblehurst Road, Horsham, West Sussex RH12 5AB, United Kingdom.

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http://dx.doi.org/10.1016/j.bmcl.2013.11.074DOI Listing
January 2014

An unvalidated online risk predictor tool for melanoma.

Australas J Dermatol 2013 Nov;54(4):e97

Preventive and Social Medicine, Hugh Adam Cancer Epidemiology Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1111/ajd.12084DOI Listing
November 2013

Bowel cancer screening in New Zealand.

N Z Med J 2013 Nov 1;126(1385):89-90. Epub 2013 Nov 1.

Hugh Adam Cancer Epidemiology Unit, University of Otago, Dunedin, New Zealand.

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November 2013