Brian B Graham

Brian B Graham

UNVERIFIED PROFILE

Are you Brian B Graham?   Register this Author

Register author
Brian B Graham

Brian B Graham

Publications by authors named "Brian B Graham"

Are you Brian B Graham?   Register this Author

61Publications

1032Reads

28Profile Views

The Role of Type 2 Inflammation in -Induced Pulmonary Hypertension.

Front Immunol 2019 24;10:27. Epub 2019 Jan 24.

Program in Translational Lung Research, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353826PMC
December 2019

Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.

Eur Respir J 2019 Dec 12;54(6). Epub 2019 Dec 12.

Cardiovascular Pulmonary Research Laboratories, Division of Pulmonary Sciences and Critical Care Medicine, Division of Pediatrics-Critical Care, Depts of Medicine and Pediatrics, University of Colorado, Aurora, CO, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.00378-2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911916PMC
December 2019

Interstitial Macrophage-Derived Thrombospondin-1 Contributes to Hypoxia-Induced Pulmonary Hypertension.

Cardiovasc Res 2019 Nov 9. Epub 2019 Nov 9.

Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, University of California San Francisco, USA, Building 100, 3rd floor, 1001 Potrero Ave, San Francisco, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cvr/cvz304DOI Listing
November 2019

Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome.

Am J Respir Cell Mol Biol 2019 06;60(6):637-649

1 Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.

View Article

Download full-text PDF

Source
https://www.atsjournals.org/doi/10.1165/rcmb.2018-0368OC
Publisher Site
http://dx.doi.org/10.1165/rcmb.2018-0368OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543748PMC
June 2019

BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.

Circulation 2019 05;139(19):2238-2255

Center for Pulmonary Vascular Biology and Medicine, Center for Metabolism and Mitochondrial Medicine, Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, Division of Cardiology and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, PA (Q.Y., Y.-Y.T., Y.T., J.Z., V.N., M.K.C., J.P., W.S., J.S., M.R., M.S., N.K., T.S., M.Z., N.F., S.S., S.Y.C.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519484PMC
May 2019

Common genetic variants in pulmonary arterial hypertension.

Lancet Respir Med 2019 Mar 5;7(3):190-191. Epub 2018 Dec 5.

Program in Translational Lung Research, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(18)30448-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768546PMC
March 2019

Finding the Target: In Silico and Genetic Screening for Mechanistically Novel Drugs in Pulmonary Arterial Hypertension.

Am J Respir Crit Care Med 2019 01;199(1):9-11

2 Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201808-1427EDDOI Listing
January 2019

Paclitaxel blocks Th2-mediated TGF-β activation in Schistosoma mansoni-induced pulmonary hypertension.

Pulm Circ 2019 Jan-Mar;9(1):2045894018820813. Epub 2018 Dec 4.

Program in Translational Lung Research, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2045894018820813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304706PMC
December 2018

Urocortin 2: will a drug targeting both the vasculature and the right ventricle be the future of pulmonary hypertension therapy?

Cardiovasc Res 2018 07;114(8):1057-1059

Cardiovascular Pulmonary Research Laboratories, Departments of Pediatrics and Medicine; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cvr/cvy117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279057PMC
July 2018

Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension.

Cardiovasc Res 2018 03;114(4):551-564

Pulmonary and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, RC2, B131, Aurora, CO 80045, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/cardiovascres/article/114/4/551/482
Publisher Site
http://dx.doi.org/10.1093/cvr/cvy004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852549PMC
March 2018

A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.

J Immunol 2017 06 12;198(12):4802-4812. Epub 2017 May 12.

Cardiovascular Pulmonary Research Laboratories, Departments of Pediatrics and Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1601692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501258PMC
June 2017

Fatty Acid Metabolism, Bone Morphogenetic Protein Receptor Type 2, and the Right Ventricle.

Am J Respir Crit Care Med 2016 09;194(6):655-6

1 Department of Medicine University of Colorado Anschutz Medical Campus Aurora, Colorado.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201603-0592EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027232PMC
September 2016

Severe pulmonary hypertension is associated with altered right ventricle metabolic substrate uptake.

Am J Physiol Lung Cell Mol Physiol 2015 Sep 26;309(5):L435-40. Epub 2015 Jun 26.

Department of Medicine, University of Colorado Denver, Aurora, Colorado;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00169.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556932PMC
September 2015

The crossroads of iron with hypoxia and cellular metabolism. Implications in the pathobiology of pulmonary hypertension.

Am J Respir Cell Mol Biol 2014 Dec;51(6):721-9

1 Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2014-0021TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291546PMC
December 2014

Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation.

Am J Pathol 2014 Sep 9;184(9):2382-9. Epub 2014 Jul 9.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2014.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188171PMC
September 2014

Schistosomiasis and the pulmonary vasculature (2013 Grover Conference series).

Pulm Circ 2014 Sep;4(3):353-62

Program in Translational Lung Research, University of Colorado Denver, Aurora, Colorado, USA; and Pulmonary Vascular Research Institute.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/675983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278594PMC
September 2014

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.

J Immunol 2014 Jul 13;193(2):597-609. Epub 2014 Jun 13.

Division of Critical Care Medicine/Cardiovascular Pulmonary Research Laboratories, Department of Pediatrics and Medicine, School of Medicine, University of Colorado Denver, Aurora, CO 80045;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1303048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100597PMC
July 2014

Role of vascular endothelial growth factor signaling in Schistosoma-induced experimental pulmonary hypertension.

Pulm Circ 2014 Jun;4(2):289-99

Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USA ; Pulmonary Vascular Research Institute.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1086/675992
Publisher Site
http://dx.doi.org/10.1086/675992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070790PMC
June 2014

Fat and cardiotoxicity in hereditary pulmonary hypertension.

Am J Respir Crit Care Med 2014 Feb;189(3):247-9

1 Division of Pulmonary Sciences and Critical Care Medicine University of Colorado School of Medicine Aurora, Colorado.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201312-2240EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977738PMC
February 2014

Pathology of pulmonary hypertension.

Clin Chest Med 2013 Dec 17;34(4):639-50. Epub 2013 Oct 17.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, 12700 East 19th Avenue, Research Complex 2, Room 9001, Aurora, CO 80045, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccm.2013.08.009DOI Listing
December 2013

Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease.

Am J Physiol Lung Cell Mol Physiol 2013 Nov 13;305(10):L725-36. Epub 2013 Sep 13.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Univ. of Colorado Denver, Anschutz Medical Campus, Research 2 - 9th floor, Rm. 9001; Mail stop C-272, 12700 East 19th Ave., Aurora, CO 80045.

View Article

Download full-text PDF

Source
http://www.physiology.org/doi/10.1152/ajplung.00186.2013
Publisher Site
http://dx.doi.org/10.1152/ajplung.00186.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840271PMC
November 2013

Updated approach for the assessment of ventilator-associated pneumonia.

Crit Care Med 2013 Nov;41(11):2641-2

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Aurora, CO.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e3182a84be1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828199PMC
November 2013

Transforming growth factor-β signaling promotes pulmonary hypertension caused by Schistosoma mansoni.

Circulation 2013 Sep 19;128(12):1354-64. Epub 2013 Aug 19.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine (B.B.G., J.C., L.G., J.P., E.D., L.D., T.T., L.S., N.D., R.W.V.) and Department of Pathology (X.-J.W.), Anschutz Medical Campus, Aurora, CO; Pulmonary Vascular Research Institute (B.B.G., A.B., H.C.C., G.B., R.M.T.); Memorial S. Jose Hospital, Universidade de Pernambuco in Recife, Recife, Brazil (A.B.); Division of Cardiology, University of Pittsburgh, Pittsburgh, PA (H.C.C.); School of Pharmacy, University of Kent, Kent, UK (G.B.); and Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (T.A.W.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880024PMC
September 2013

A sinus venosus atrial septal defect is diagnosed by echocardiography with an unusual bubble study.

Echocardiography 2013 Jul 1;30(6):E182-3. Epub 2013 Apr 1.

Division of Cardiology, School of Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/echo.12191DOI Listing
July 2013

Significant intrapulmonary Schistosoma egg antigens are not present in schistosomiasis-associated pulmonary hypertension.

Pulm Circ 2011 Oct-Dec;1(4):456-61

Department of Medicine, Program in Translational Lung Research, University of Colorado Denver, Denver, CO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/2045-8932.93544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329075PMC
August 2012

Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension.

Am J Respir Crit Care Med 2012 Feb 10;185(3):260-6. Epub 2011 Nov 10.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201108-1536PPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297113PMC
February 2012

Tracheal Basal cells: a facultative progenitor cell pool.

Am J Pathol 2010 Jul 3;177(1):362-76. Epub 2010 Jun 3.

Department of Pediatrics, Division of Cell Biology, National Jewish Health, Denver, Colorado, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893679PMC
July 2010

Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective.

Chest 2010 Jun;137(6 Suppl):20S-29S

Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado at Denver, Aurora, CO 80045, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00123692106032
Publisher Site
http://dx.doi.org/10.1378/chest.10-0048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989787PMC
June 2010

Diabetes mellitus does not adversely affect outcomes from a critical illness.

Crit Care Med 2010 Jan;38(1):16-24

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Denver, CO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e3181b9eaa5DOI Listing
January 2010

[Pathogenesis of pulmonary hypertension].

Zhonghua Yi Xue Za Zhi 2009 Aug;89(30):2091-3

Division of Pulmonary Medicine and Critical Care Sciences, University of Colorado at Denver and Health Sciences Center, USA.

View Article

Download full-text PDF

Source
August 2009

Clinical problem-solving. Kiss of death.

N Engl J Med 2009 Jun;360(24):2564-8

Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMcps0806935DOI Listing
June 2009

Dyspnea, chest pain, and altered mental status in a 33-year-old carpenter.

Chest 2008 Nov;134(5):1074-1079

Division of Pulmonary Medicine, National Jewish Health and Research Center, Denver, CO.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.08-1135DOI Listing
November 2008

Cigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung.

Am J Respir Cell Mol Biol 2008 Jul 25;39(1):1-6. Epub 2008 Apr 25.

Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Denver, School of Medicine, 4200 East 9th Avenue, Campus Box C272, Denver, CO 80262, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2008-0117TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720121PMC
July 2008

Primary pulmonary lymphoma.

Ann Thorac Surg 2005 Oct;80(4):1248-53

Department of Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2005.04.014DOI Listing
October 2005

End-to-side venous anastomosis with the internal jugular vein stump: a preliminary report.

Head Neck 2004 Jun;26(6):537-40

Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hed.20004
Publisher Site
http://dx.doi.org/10.1002/hed.20004DOI Listing
June 2004

Pediatric tracheal surgery.

Ann Thorac Surg 2002 Aug;74(2):308-13; discussion 314

Division of General Thoracic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0003-4975(02)03613-5DOI Listing
August 2002