Brian A Walker

Brian A Walker

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Brian A Walker

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Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://dx.doi.org/10.1038/s41467-018-08107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Knick-knack PADIMAC.

Authors:
Brian A Walker

Blood 2018 Nov;132(20):2110-2111

University of Arkansas for Medical Sciences.

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http://dx.doi.org/10.1182/blood-2018-10-875138DOI Listing
November 2018

The genomic features associated with high-risk multiple myeloma.

Oncotarget 2018 Oct 26;9(84):35478-35479. Epub 2018 Oct 26.

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR.

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http://dx.doi.org/10.18632/oncotarget.26269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231458PMC
October 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-04989-w
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http://dx.doi.org/10.1038/s41467-018-04989-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.

BMC Cancer 2018 Jul 6;18(1):724. Epub 2018 Jul 6.

Myeloma Institute, University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, 4301 West Markham St., Slot 776, Rm 914, Little Rock, AR, 72205, USA.

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http://dx.doi.org/10.1186/s12885-018-4602-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035431PMC
July 2018

Whole Exome Sequencing in Multiple Myeloma to Identify Somatic Single Nucleotide Variants and Key Translocations Involving Immunoglobulin Loci and MYC.

Authors:
Brian A Walker

Methods Mol Biol 2018 ;1792:71-95

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.1007/978-1-4939-7865-6_6DOI Listing
January 2018

A Rapid and Robust Protocol for Reduced Representation Bisulfite Sequencing in Multiple Myeloma.

Methods Mol Biol 2018 ;1792:179-191

Department of Internal Medicine, Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.1007/978-1-4939-7865-6_13DOI Listing
January 2018

Correction to: A Rapid and Robust Protocol for Reduced Representation Bisulfite Sequencing in Multiple Myeloma.

Methods Mol Biol 2018 ;1792:E3

Department of Internal Medicine, Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.1007/978-1-4939-7865-6_17DOI Listing
January 2018

Phenotypic characterization of epibulbar dermoids.

Int Ophthalmol 2017 Jun 12;37(3):499-505. Epub 2016 Jul 12.

Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s10792-016-0285-5DOI Listing
June 2017

Understanding next generation sequencing in oncology: A guide for oncologists.

Crit Rev Oncol Hematol 2015 Dec 29;96(3):463-74. Epub 2015 Jun 29.

The Royal Marsden NHS Foundation Trust, Surrey, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2015.06.007DOI Listing
December 2015

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

J Clin Oncol 2015 Nov 17;33(33):3911-20. Epub 2015 Aug 17.

Brian A. Walker, Eileen M. Boyle, Christopher P. Wardell, Alex Murison, Dil B. Begum, Nasrin M. Dahir, Paula Z. Proszek, David C. Johnson, Martin F. Kaiser, Lorenzo Melchor, Lauren I. Aronson, Charlotte Pawlyn, Fabio Mirabella, John R. Jones, Annamaria Brioli, Faith E. Davies, and Gareth J. Morgan, The Institute of Cancer Research, London; Matthew Scales, The Institute of Cancer Research, Surrey; David A. Cairns, Walter M. Gregory, and Ana Quartilho, University of Leeds; Gordon Cook, St James's University Hospital, Leeds; Mark T. Drayson, University of Birmingham, Birmingham; Nigel Russell, Nottingham University Hospital, Nottingham; Graham H. Jackson, Newcastle University, Newcastle upon Tyne, United Kingdom; Aneta Mikulasova, Masaryk University, Brno, Czech Republic; and Xavier Leleu, Hôpital C. Huriez, Centre Hospitalier Régional Universitaire de Lille, Lille, France.

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http://ascopubs.org/doi/10.1200/JCO.2014.59.1503
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http://dx.doi.org/10.1200/JCO.2014.59.1503DOI Listing
November 2015

The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway.

Oncotarget 2015 Jul;6(19):17314-27

Haemato-Oncology Research Unit, Division of Molecular Pathology, Cancer Therapeutics and Clinical Studies, The Institute of Cancer Research, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627310PMC
http://dx.doi.org/10.18632/oncotarget.1168DOI Listing
July 2015

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma.

Genes Chromosomes Cancer 2015 Feb 7;54(2):91-8. Epub 2014 Oct 7.

Division of Molecular Pathology, The Institute of Cancer Research, London, UK; Service des maladies du Sang, Hopital Huriez, Centre Hospitalier Regional Universitaire de Lille, Lille, France.

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http://dx.doi.org/10.1002/gcc.22222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310140PMC
February 2015

Biology and treatment of myeloma.

Clin Lymphoma Myeloma Leuk 2014 Sep;14 Suppl:S65-70

Centre for Myeloma Research, Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2014.06.011DOI Listing
September 2014

Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR.

Genes Chromosomes Cancer 2013 Sep 13;52(9):817-22. Epub 2013 Jun 13.

Molecular Haematology, Haemato-Oncology Research Unit, Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1002/gcc.22077DOI Listing
September 2013

Improved risk stratification in myeloma using a microRNA-based classifier.

Br J Haematol 2013 Aug 30;162(3):348-59. Epub 2013 May 30.

Section of Haemato-Oncology, Institute of Cancer Research, Sutton, Surrey, UK.

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http://dx.doi.org/10.1111/bjh.12394DOI Listing
August 2013

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

Blood 2013 Jul 22;122(2):219-26. Epub 2013 May 22.

Haemato-Oncology Research Unit, Division of Molecular Pathology, The Institute of Cancer Research, Cotswold Rd, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1182/blood-2013-03-487884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709654PMC
July 2013

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

Blood 2013 Apr 22;121(17):3413-9. Epub 2013 Feb 22.

Molecular Haematology, Haemato-Oncology Research Unit, Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-12-47
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http://dx.doi.org/10.1182/blood-2012-12-471888DOI Listing
April 2013

The genetic architecture of multiple myeloma.

Nat Rev Cancer 2012 Apr 12;12(5):335-48. Epub 2012 Apr 12.

Haemato-oncology Research Unit, Division of Molecular Pathology, The Institute of Cancer Research and Royal Marsden Hospital, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK.

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http://www.nature.com/articles/nrc3257
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http://dx.doi.org/10.1038/nrc3257DOI Listing
April 2012

The reconstruction of transcriptional networks reveals critical genes with implications for clinical outcome of multiple myeloma.

Clin Cancer Res 2011 Dec 2;17(23):7402-12. Epub 2011 Sep 2.

Department of Medical Sciences, University of Milan and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0596DOI Listing
December 2011

A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment.

Clin Cancer Res 2011 Oct 19;17(19):6347-55. Epub 2011 Aug 19.

Section of Haemato-Oncology Research Unit, Division of Molecular Pathology, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-11-0994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866998PMC
October 2011

Could DNA methylation become a useful measure for multiple myeloma prognoses?

Expert Rev Hematol 2011 Apr;4(2):125-7

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http://dx.doi.org/10.1586/ehm.11.7DOI Listing
April 2011

Aminopeptidase inhibition as a targeted treatment strategy in myeloma.

Mol Cancer Ther 2009 Apr;8(4):762-70

Section of Haemato-Oncology, Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0735DOI Listing
April 2009

Energy expenditure of sedentary screen time compared with active screen time for children.

Pediatrics 2006 Dec;118(6):e1831-5

Endocrine Research Unit, Mayo Clinic, 200 First St, SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1542/peds.2006-1087DOI Listing
December 2006

Use of single nucleotide polymorphism-based mapping arrays to detect copy number changes and loss of heterozygosity in multiple myeloma.

Clin Lymphoma Myeloma 2006 Nov;7(3):186-91

Section of Haemato-Oncology, Institute of Cancer Research, Surrey, UK.

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http://dx.doi.org/10.3816/CLM.2006.n.057DOI Listing
November 2006

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma.

Blood 2006 Sep 16;108(5):1733-43. Epub 2006 May 16.

Section of Haemato-Oncology, Institute for Cancer Research, 15 Cotswold Rd, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1182/blood-2006-02-005496DOI Listing
September 2006

Chicken TAP genes differ from their human orthologues in locus organisation, size, sequence features and polymorphism.

Immunogenetics 2005 May 2;57(3-4):232-47. Epub 2005 Apr 2.

Institute For Animal Health, Compton, Nr Newbury, Berkshire, RG20 7NN, UK.

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http://link.springer.com/10.1007/s00251-005-0786-2
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http://dx.doi.org/10.1007/s00251-005-0786-2DOI Listing
May 2005

A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms.

Nature 2004 Dec;432(7018):717-22

Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing Proteomics Institute, Beijing 101300, China.

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http://dx.doi.org/10.1038/nature03156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263125PMC
December 2004