Publications by authors named "Brenton R Paolella"

16Publications

Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids.

ACS Chem Biol 2020 06 11;15(6):1358-1369. Epub 2020 May 11.

Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/acschembio.9b01027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521945PMC
June 2020

Gliomas "Dope Up" for Growth.

Cancer Cell 2016 06;29(6):778-780

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.05.010DOI Listing
June 2016

Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells.

Stem Cells 2016 05 1;34(5):1321-31. Epub 2016 Feb 1.

Pharmacology and Toxicology, Norris Cotton Cancer Center, One Medical Center Drive, Lebanon, NH, 03756.

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http://dx.doi.org/10.1002/stem.2291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024556PMC
May 2016

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.

Neuro Oncol 2015 Nov 29;17(11):1486-96. Epub 2015 Mar 29.

Department of Cancer Biology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, Massachusetts (G.B., P.B., B.R.P., S.E.S., B.T., R.F.-L., C.S., R.S., R.B.); Broad Institute, Cambridge, Massachusetts (G.B., P.B., B.R.P., S.E.S., B.T., R.F.-L., T.G., R.B.); Pediatric Neuro-Oncology Program, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Dana-Farber Cancer Institute and Boston Children's Hospital, and Harvard Medical School, Boston, Massachusetts (P.B., L.C.G., M.W.K.); Liver Cancer Program, Tisch Cancer Institute, Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York (Y.H.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.R., S.S., P.Y.W., A.H.L., K.L.L., J.A.C.); Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts (S.R., L.R., B.R., C.L.M., K.L.L.); Department of Neurosurgery, Acibadem University Medical Center, Istanbul, Turkey (M.O.); Department of Pathology, Acibadem University Medical Center, Istanbul, Turkey (A.S.); Department of Neurosurgery, Boston Children's Hospital, Boston, Massachusetts (L.C.G.); Departement de Cancerologie de l'enfant et de l'adolescent, Gustave Roussy and Unité Mixte de Recherche 8203 du Centre National de la Recherche Scientifique, Université Paris-Sud, Villejuif, France (J.G.); Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (K.L.L.).

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http://dx.doi.org/10.1093/neuonc/nov045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648300PMC
November 2015

Id2 mediates oligodendrocyte precursor cell maturation arrest and is tumorigenic in a PDGF-rich microenvironment.

Cancer Res 2014 Mar 14;74(6):1822-32. Epub 2014 Jan 14.

Authors' Affiliations: Norris Cotton Cancer Center; Departments of Genetics; Pediatrics; and Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061294PMC
http://dx.doi.org/10.1158/0008-5472.CAN-13-1839DOI Listing
March 2014

BET bromodomain inhibition of MYC-amplified medulloblastoma.

Clin Cancer Res 2014 Feb 2;20(4):912-25. Epub 2013 Dec 2.

Authors' Affiliations: Departments of Cancer Biology and Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School; Pediatric Neuro-Oncology, Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Pediatric Hematology/Oncology, Boston Children's Hospital; Center for Cancer Genome Characterization, Dana-Farber Cancer Institute, Boston; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Departments of Neurology and Neurological Sciences and Neurosurgery, Stanford University School of Medicine; Stanford Cancer Institute, Stanford University Medical Center, Stanford; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla; Department of Neurology, Pediatrics, and Neurosurgery, University of California, San Francisco, California; and Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://clincancerres.aacrjournals.org/content/20/4/912.full.
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-2281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198154PMC
February 2014

Behavioral abnormalities and Parkinson's-like histological changes resulting from Id2 inactivation in mice.

Dis Model Mech 2013 May 20;6(3):819-27. Epub 2012 Dec 20.

Norris Cotton Cancer Center and Department of Pediatrics, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1242/dmm.010041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634664PMC
May 2013

p53 directly represses Id2 to inhibit the proliferation of neural progenitor cells.

Stem Cells 2011 Jul;29(7):1090-101

Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.1002/stem.660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647692PMC
July 2011