Brenda Lilly

Brenda Lilly

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Brenda Lilly

Brenda Lilly

Publications by authors named "Brenda Lilly"

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31Publications

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Evaluation of Notch3 Deficiency in Diabetes-Induced Pericyte Loss in the Retina.

J Vasc Res 2018 22;55(5):308-318. Epub 2018 Oct 22.

Center for Cardiovascular Research, Columbus, Ohio,

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https://www.karger.com/Article/FullText/493151
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http://dx.doi.org/10.1159/000493151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280662PMC
September 2019

Analysis of Uncharacterized Expression during Mouse Development and Cardiovascular Morphogenesis.

J Cardiovasc Dev Dis 2019 06 22;6(2). Epub 2019 Jun 22.

HB Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.3390/jcdd6020024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617212PMC
June 2019

Endothelial cell-induced cytoglobin expression in vascular smooth muscle cells contributes to modulation of nitric oxide.

Vascul Pharmacol 2018 11 30;110:7-15. Epub 2018 Jun 30.

Center for Cardiovascular Research, The Ohio State University, Columbus, OH, USA; The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.vph.2018.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135703PMC
November 2018

Loss of Notch2 and Notch3 in vascular smooth muscle causes patent ductus arteriosus.

Genesis 2015 Dec 30;53(12):738-48. Epub 2015 Oct 30.

Nationwide Children's Hospital, Center for Cardiovascular and Pulmonary Research and the Heart Center, Columbus, Ohio.

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http://dx.doi.org/10.1002/dvg.22904DOI Listing
December 2015

Potential Molecular Mechanism of Retrograde Aortic Arch Stenosis in the Hybrid Approach to Hypoplastic Left Heart Syndrome.

Ann Thorac Surg 2015 Sep 7;100(3):1013-9; discussion 1019-20. Epub 2015 Jul 7.

The Heart Center, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio; Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00034975150080
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http://dx.doi.org/10.1016/j.athoracsur.2015.04.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567479PMC
September 2015

Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.

J Biol Chem 2015 Jun 8;290(26):16226-37. Epub 2015 May 8.

From the Center for Cardiovascular and Pulmonary Research, and The Heart Center at Nationwide Children's Hospital, and the Department of Pediatrics, The Ohio State University, Columbus, Ohio 43205

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http://dx.doi.org/10.1074/jbc.M115.655548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481222PMC
June 2015

Temporal and embryonic lineage-dependent regulation of human vascular SMC development by NOTCH3.

Stem Cells Dev 2015 Apr 25;24(7):846-56. Epub 2015 Feb 25.

1 Anne Mclaren Laboratory for Regenerative Medicine, Wellcome Trust-Medical Research Council, Cambridge Stem Cell Institute, University of Cambridge , Cambridge, United Kingdom .

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http://dx.doi.org/10.1089/scd.2014.0520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367523PMC
April 2015

MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.

Circ Res 2015 Jan 16;116(1):23-34. Epub 2014 Oct 16.

From the Center for Cardiovascular and Pulmonary Research and Heart Center, Nationwide Children's Hospital, Department of Pediatrics, The Ohio State University, Columbus.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.303970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299754PMC
January 2015

Evidence of Aortopathy in Mice with Haploinsufficiency of in -Null Background.

J Cardiovasc Dev Dis 2015;2(1):17-30

The Center for Cardiovascular and Pulmonary Research and Heart Center, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA ; Department of Pediatrics, The Ohio State University, 700 Children's Drive, Columbus, OH 43205, USA ; Department of Molecular Genetics, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.3390/jcdd2010017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407710PMC
January 2015

Endothelial cells direct mesenchymal stem cells toward a smooth muscle cell fate.

Stem Cells Dev 2014 Nov 14;23(21):2581-90. Epub 2014 Jul 14.

Department of Pediatrics, The Heart Center, Nationwide Children's Hospital, The Ohio State University , Columbus, Ohio.

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https://www.liebertpub.com/doi/10.1089/scd.2014.0163
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http://dx.doi.org/10.1089/scd.2014.0163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201243PMC
November 2014

Notch signaling governs phenotypic modulation of smooth muscle cells.

Vascul Pharmacol 2014 Nov;63(2):88-96

Nationwide Children's Hospital, The Heart Center, Department of Pediatrics, The Ohio State University, Columbus, OH, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15371891140016
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http://dx.doi.org/10.1016/j.vph.2014.09.004DOI Listing
November 2014

We have contact: endothelial cell-smooth muscle cell interactions.

Authors:
Brenda Lilly

Physiology (Bethesda) 2014 Jul;29(4):234-41

Department of Pediatrics, Nationwide Children's Hospital, The Heart Center, The Ohio State University, Columbus, Ohio

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http://dx.doi.org/10.1152/physiol.00047.2013DOI Listing
July 2014

Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.

J Mol Cell Cardiol 2013 Jul 11;60:27-35. Epub 2013 Apr 11.

Center for Cardiovascular and Pulmonary Research at Nationwide Children's Hospital, Columbus, OH 43205, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2013.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058883PMC
July 2013

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

PLoS One 2012 17;7(5):e37365. Epub 2012 May 17.

Center for Cardiovascular and Pulmonary Research, Nationwide Children's Hospital, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037365PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355134PMC
September 2012

Reciprocal regulation of syndecan-2 and Notch signaling in vascular smooth muscle cells.

J Biol Chem 2012 May 21;287(20):16111-20. Epub 2012 Mar 21.

Center for Cardiovascular and Pulmonary Research, Nationwide Children's Hospital, Columbus, Ohio 43205, USA.

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http://dx.doi.org/10.1074/jbc.M111.322107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351283PMC
May 2012

Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis.

Biochem Pharmacol 2012 Apr 18;83(7):866-73. Epub 2012 Jan 18.

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.bcp.2012.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288401PMC
April 2012

Endothelial cells downregulate apolipoprotein D expression in mural cells through paracrine secretion and Notch signaling.

Am J Physiol Heart Circ Physiol 2011 Sep 24;301(3):H784-93. Epub 2011 Jun 24.

Vascular Biology Center, Medical College of Georgia, Augusta, Georgia, USA.

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http://dx.doi.org/10.1152/ajpheart.00116.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191092PMC
September 2011

Notch3 is critical for proper angiogenesis and mural cell investment.

Circ Res 2010 Oct 5;107(7):860-70. Epub 2010 Aug 5.

National Children's Research Institute, The Ohio State University, Columbus, OH 43205, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.218271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948576PMC
October 2010

Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse.

Arterioscler Thromb Vasc Biol 2010 Apr 7;30(4):694-701. Epub 2010 Jan 7.

Huntsman Cancer Institute, Department of Biology, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.200741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998921PMC
April 2010

NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1.

Circ Res 2009 Feb 15;104(4):466-75. Epub 2009 Jan 15.

Vascular Biology Center and Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.108.184846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747310PMC
February 2009

Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling.

Physiol Genomics 2009 Jan 4;36(2):69-78. Epub 2008 Nov 4.

Vascular Biology Center and Department of Obstetrics and Gynecology, Medical College of Georgia, 1459 Laney Walker Blvd., Augusta, GA 30912, USA.

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http://dx.doi.org/10.1152/physiolgenomics.90318.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636923PMC
January 2009

Fibroblasts potentiate blood vessel formation partially through secreted factor TIMP-1.

Angiogenesis 2008 14;11(3):223-34. Epub 2008 Feb 14.

Vascular Biology Center, Department of Obstetrics and Gynecology, Medical College of Georgia, 1459 Laney Walker Blvd., Augusta, GA 30912, USA.

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http://dx.doi.org/10.1007/s10456-008-9102-8DOI Listing
December 2008

Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice.

Genesis 2008 Mar;46(3):167-76

Cardiovascular Development Group, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://doi.wiley.com/10.1002/dvg.20379
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http://dx.doi.org/10.1002/dvg.20379DOI Listing
March 2008

Transforming growth factor-beta (TGF- 1) down-regulates Notch3 in fibroblasts to promote smooth muscle gene expression.

J Biol Chem 2008 Jan 2;283(3):1324-33. Epub 2007 Nov 2.

Vascular Biology Center and Department of Obstetrics and Gynecology, Medical College of Georgia, 1459 Laney Walker Boulevard, Augusta, GA 30912, USA.

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http://dx.doi.org/10.1074/jbc.M706651200DOI Listing
January 2008

Protein kinase C and downstream signaling pathways in a three-dimensional model of phorbol ester-induced angiogenesis.

Angiogenesis 2006 11;9(2):39-51. Epub 2006 Apr 11.

Vascular Biology Center, Medical College of Georgia, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1007/s10456-006-9028-yDOI Listing
December 2006

Hypoxia-inducible factor 1alpha modulates adhesion, migration, and FAK phosphorylation in vascular smooth muscle cells.

J Cell Biochem 2005 Dec;96(5):971-85

Vascular Biology Center and Department of Obstetrics and Gynecology, Medical College of Georgia, 1459 Laney Walker Blvd., Augusta, Georgia 30912, USA.

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http://doi.wiley.com/10.1002/jcb.20559
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http://dx.doi.org/10.1002/jcb.20559DOI Listing
December 2005

Ca2+/calmodulin-dependent protein kinase IV activates cysteine-rich protein 1 through adjacent CRE and CArG elements.

Am J Physiol Cell Physiol 2005 Oct 25;289(4):C785-93. Epub 2005 May 25.

Vascular Biology Center and Department of Obstetrics and Gynecology, Medical College of Georgia, 1459 Laney Walker Blvd., CB3207, Augusta, Georgia 30912-2500, USA.

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http://dx.doi.org/10.1152/ajpcell.00098.2005DOI Listing
October 2005