Brandon W Higgs

Brandon W Higgs

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Brandon W Higgs

Brandon W Higgs

Publications by authors named "Brandon W Higgs"

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Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab.

Clin Cancer Res 2018 12 9;24(24):6212-6222. Epub 2018 Aug 9.

Translational Medicine Oncology, MedImmune, Gaithersburg, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0386DOI Listing
December 2018

Synergistic immunosuppression and unintended consequences.

Pediatr Transplant 2017 11 21;21(7). Epub 2017 Aug 21.

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/petr.13047DOI Listing
November 2017

Predicting Cellular Rejection With a Cell-Based Assay: Preclinical Evaluation in Children.

Transplantation 2017 Jan;101(1):131-140

1 Thomas E. Starzl Transplantation Institute, Hillman Center for Pediatric Transplantation, Department of Transplant Surgery, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA. 2 Plexision Inc, Pittsburgh, PA. 3 Tissue Typing Laboratory, Department of Pathology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1097/TP.0000000000001076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011025PMC
January 2017

Profile of the Pleximmune blood test for transplant rejection risk prediction.

Expert Rev Mol Diagn 2016 16;16(4):387-93. Epub 2016 Feb 16.

c Tissue Typing Laboratory, Department of Pathology , Children's Hospital of Pittsburgh of UPMC , Pittsburgh , PA , USA.

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http://dx.doi.org/10.1586/14737159.2016.1139455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965161PMC
December 2016

Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.

Sci Rep 2016 12 2;6:38347. Epub 2016 Dec 2.

Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, 4401 Penn Avenue, Pediatric Abdominal Transplant Surgery, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1038/srep38347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133573PMC
December 2016

Genome-wide association studies in biliary atresia.

Wiley Interdiscip Rev Syst Biol Med 2015 Sep-Oct;7(5):267-73. Epub 2015 May 11.

Department of Surgery, Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/wsbm.1303DOI Listing
June 2016

The Role of ARF6 in Biliary Atresia.

PLoS One 2015 17;10(9):e0138381. Epub 2015 Sep 17.

Hillman Center for Pediatric Transplantation of the Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, 15224, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138381PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574480PMC
May 2016

In Vivo Therapeutic Success of MicroRNA-155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage.

Arthritis Rheumatol 2016 Apr;68(4):953-64

Renji Hospital, Institute of Health Sciences of Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Shanghai Jiao Tong University School of Medicine, Shanghai, China, and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/art.39485DOI Listing
April 2016

CallSim: Evaluation of Base Calls Using Sequencing Simulation.

ISRN Bioinform 2012 12;2012:371718. Epub 2012 Dec 12.

Center for Biotechnology Education, Johns Hopkins University, Baltimore, MD 21218, USA.

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https://www.hindawi.com/archive/2012/371718/
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http://dx.doi.org/10.5402/2012/371718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393072PMC
May 2015

Low-frequency coding variants at 6p21.33 and 20q11.21 are associated with lung cancer risk in Chinese populations.

Am J Hum Genet 2015 May 30;96(5):832-40. Epub 2015 Apr 30.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, China; Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 211166, China. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570553PMC
May 2015

The transcription factor, T-bet, primes intestine transplantation rejection and is associated with disrupted mucosal homeostasis.

Transplantation 2015 Apr;99(4):890-4

1Division of Pediatric Pathology, Department of Pathology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA. 2Hillman Center for Pediatric Transplantation of the Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA. 3Histology Core Laboratory, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1097/TP.0000000000000445DOI Listing
April 2015

Antithymocyte globulin facilitates alloreactive T-cell apoptosis by means of caspase-3: potential implications for monitoring rejection-free outcomes.

Transplantation 2015 Jan;99(1):164-70

1 Thomas E. Starzl Transplantation Institute, Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC), Department of Transplant Surgery, Pittsburgh, PA. 2 Tissue Typing Laboratory, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

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http://dx.doi.org/10.1097/TP.0000000000000289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274752PMC
January 2015

Molecular profiling to diagnose a case of atypical dermatomyositis.

J Invest Dermatol 2013 Dec 3;133(12):2796-2799. Epub 2013 Jun 3.

Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/jid.2013.240DOI Listing
December 2013

Expression profiles of mitochondrial genes in the frontal cortex and the caudate nucleus of developing humans and mice selectively bred for high and low fear.

PLoS One 2012 13;7(11):e49183. Epub 2012 Nov 13.

Department of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049183PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496717PMC
May 2013

Mucosal plasma cell barrier disruption during intestine transplant rejection.

Transplantation 2012 Dec;94(12):1236-42

Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/TP.0b013e3182708d9dDOI Listing
December 2012

Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus.

Arthritis Rheum 2012 Nov;64(11):3715-25

Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences, Shanghai JiaoTong University School of Medicine, Chinese Academy of Sciences, China.

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http://doi.wiley.com/10.1002/art.34596
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http://dx.doi.org/10.1002/art.34596DOI Listing
November 2012

Interferon and biologic signatures in dermatomyositis skin: specificity and heterogeneity across diseases.

PLoS One 2012 3;7(1):e29161. Epub 2012 Jan 3.

Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029161PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250414PMC
May 2012

Allospecific CD154 + T-cytotoxic memory cells as potential surrogate for rejection risk in pediatric intestine transplantation.

Pediatr Transplant 2012 Feb 29;16(1):83-91. Epub 2011 Nov 29.

Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2011.01617.xDOI Listing
February 2012

Cellular alloresponses for rejection-risk assessment after pediatric transplantation.

Curr Opin Organ Transplant 2011 Oct;16(5):515-21

Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/MOT.0b013e32834a94e3DOI Listing
October 2011

Allospecific CD154+ T-cytotoxic memory cells identify recipients experiencing acute cellular rejection after renal transplantation.

Transplantation 2011 Aug;92(4):433-8

Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/TP.0b013e318225276dDOI Listing
August 2011

Gene expression and genetic variation data implicate PCLO in bipolar disorder.

Biol Psychiatry 2011 Feb 24;69(4):353-9. Epub 2010 Dec 24.

Stanley Laboratory of Brain Research, Rockville, Maryland, USA.

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http://dx.doi.org/10.1016/j.biopsych.2010.09.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278480PMC
February 2011

Allospecific CD154+ B cells associate with intestine allograft rejection in children.

Transplantation 2010 Dec;90(11):1226-31

Department of Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/TP.0b013e3181f995ceDOI Listing
December 2010

Elevated myeloid: plasmacytoid dendritic cell ratio associates with early acute cellular rejection in pediatric small bowel transplantation.

Transplantation 2010 Jan;89(1):55-60

Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1097/TP.0b013e3181bc5d9eDOI Listing
January 2010

Expression profiles of schizophrenia susceptibility genes during human prefrontal cortical development.

J Psychiatry Neurosci 2009 Nov;34(6):450-8

Stanley Medical Research Institute, Rockville, MD 20850, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783436PMC
November 2009

Allospecific CD154+ T cells identify rejection-prone recipients after pediatric small-bowel transplantation.

Surgery 2009 Aug 26;146(2):166-73. Epub 2009 Jun 26.

Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.surg.2009.04.006DOI Listing
August 2009

Meta-analysis of 12 genomic studies in bipolar disorder.

J Mol Neurosci 2007 ;31(3):221-43

Elashoff Consulting, Germantown, MD 20876, USA.

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February 2008

An online database for brain disease research.

BMC Genomics 2006 Apr 4;7:70. Epub 2006 Apr 4.

Elashoff Consulting LLC, Germantown, MD 20876, USA.

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http://dx.doi.org/10.1186/1471-2164-7-70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489945PMC
April 2006

Spectral embedding finds meaningful (relevant) structure in image and microarray data.

BMC Bioinformatics 2006 Feb 16;7:74. Epub 2006 Feb 16.

School of Computational Sciences, George Mason University, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1186/1471-2105-7-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395341PMC
February 2006