Publications by authors named "Brandon B Holmes"

19Publications

Adult-Onset Subacute Sclerosing Panencephalitis With a 30-Year Latent Period.

Neurohospitalist 2020 Apr 18;10(2):127-132. Epub 2019 Aug 18.

Department of Neurology, University of California, San Francisco, CA, USA.

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April 2020

A synthetic heparinoid blocks Tau aggregate cell uptake and amplification.

J Biol Chem 2020 03 23;295(10):2974-2983. Epub 2020 Jan 23.

Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390

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March 2020

Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics.

J Biol Chem 2019 01 26;294(3):1045-1058. Epub 2018 Nov 26.

the Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.

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January 2019

Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau α-synuclein and β-amyloid aggregates.

J Biol Chem 2018 07 11;293(27):10826-10840. Epub 2018 May 11.

From the Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390,

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July 2018

Vertebrobasilar Dolichoectasia Causing An Optic Tract Syndrome.

J Neuroophthalmol 2017 06;37(2):179-181

Medical Scientist Training Program (BBH), Washington University School of Medicine, St. Louis, Missouri Departments of Ophthalmology and Visual Sciences (WCG, NHK, GPVS) and Otolaryngology-Head & Neck Surgery (JAG), Washington University, St. Louis, Missouri.

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June 2017

Cellular Models for the Study of Prions.

Cold Spring Harb Perspect Med 2017 Feb 1;7(2). Epub 2017 Feb 1.

Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390.

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February 2017

Prions and Protein Assemblies that Convey Biological Information in Health and Disease.

Neuron 2016 Feb;89(3):433-48

Center for Alzheimer's and Neurodegenerative Diseases, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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February 2016

Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells.

Mol Neurodegener 2016 Jan 22;11. Epub 2016 Jan 22.

Department of Neurological Surgery, Washington University School of Medicine, Hope Center Program on Protein Aggregation and Neurodegeneration, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Campus Box 8057, 660 South Euclid Avenue, St. Louis, Missouri, 63110, USA.

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January 2016

Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry.

J Vis Exp 2015 Dec 8(106):e53205. Epub 2015 Dec 8.

Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center.

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December 2015

Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation.

J Biol Chem 2015 Jun 17;290(24):14893-903. Epub 2015 Apr 17.

From the Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390 and

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June 2015

Proteopathic tau seeding predicts tauopathy in vivo.

Proc Natl Acad Sci U S A 2014 Oct 26;111(41):E4376-85. Epub 2014 Sep 26.

Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, and

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October 2014

Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target.

J Biol Chem 2014 Jul 23;289(29):19855-61. Epub 2014 May 23.

From the Department of Neurology, Washington University in St. Louis, St. Louis, Missouri 63110

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July 2014

An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1.

J Biol Chem 2013 Mar 14;288(9):6063-71. Epub 2013 Jan 14.

Department of Neurology, Washington University, St Louis, Missouri 63110, USA.

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March 2013

Amyotrophic lateral sclerosis and organ donation: is there risk of disease transmission?

Ann Neurol 2012 Dec;72(6):832-6

Department of Neurology, Hope Center for Neurological Disorders, Washington University in St Louis, School of Medicine, St Louis, MO 63110, USA.

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December 2012

Cellular mechanisms of protein aggregate propagation.

Curr Opin Neurol 2012 Dec;25(6):721-6

Department of Neurology, Washington University in St Louis, Missouri 63110, USA.

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December 2012

Trans-cellular propagation of Tau aggregation by fibrillar species.

J Biol Chem 2012 Jun 29;287(23):19440-51. Epub 2012 Mar 29.

Department of Neurology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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June 2012