Bradley E Bernstein

Oral Oncol 2019 Dec 6;99:104458. Epub 2019 Nov 6.

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA. Electronic address:

Cancer Cell 2019 Nov 17;36(5):528-544.e10. Epub 2019 Oct 17.

Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

Nat Cell Biol 2019 Nov 28;21(11):1449-1461. Epub 2019 Oct 28.

Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.

Nature 2019 11 16;575(7781):229-233. Epub 2019 Oct 16.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Nat Med 2019 Oct;25(10):1627

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Nat Commun 2019 09 18;10(1):4258. Epub 2019 Sep 18.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

Leukemia 2019 08 31;33(8):2061-2077. Epub 2019 Jan 31.

Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.

Nat Med 2019 08 1;25(8):1260-1265. Epub 2019 Jul 1.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Cell 2019 Aug 18;178(4):835-849.e21. Epub 2019 Jul 18.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

Nature 2019 08 24;572(7767):74-79. Epub 2019 Jul 24.

Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA.

Nat Commun 2019 04 23;10(1):1874. Epub 2019 Apr 23.

New York Genome Center, New York, 10013, NY, USA.

Cell 2019 03 28;176(6):1265-1281.e24. Epub 2019 Feb 28.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Ludwig Center at Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

Nat Neurosci 2019 01 17;22(1):37-46. Epub 2018 Dec 17.

Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.

Nat Genet 2019 01 17;51(1):19-25. Epub 2018 Dec 17.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Nat Commun 2018 09 4;9(1):3588. Epub 2018 Sep 4.

Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

Cancer Cell 2018 09;34(3):358-360

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

Cell 2018 09 13;175(1):101-116.e25. Epub 2018 Sep 13.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

Mol Cell 2018 06 7;70(5):983. Epub 2018 Jun 7.

Nat Genet 2018 04 9;50(4):621-629. Epub 2018 Apr 9.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Cancer Cell 2018 04;33(4):785-787

Science 2018 04;360(6386):331-335

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Nat Biotechnol 2018 02 18;36(2):179-189. Epub 2017 Dec 18.

Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.

Cancer Cell 2018 01 14;33(1):29-43.e7. Epub 2017 Dec 14.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

Cell 2017 Dec 30;171(7):1611-1624.e24. Epub 2017 Nov 30.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

Cell 2017 Oct;171(2):305-320.e24

The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Center for Theoretical Biological Physics, Rice University, Houston, TX 77030, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Departments of Computer Science and Computational and Applied Mathematics, Rice University, Houston, TX 77030, USA. Electronic address:

Cell Rep 2017 Oct;21(3):784-797

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

Elife 2017 09 11;6. Epub 2017 Sep 11.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, United States.

Nature 2017 07 5;547(7663):355-359. Epub 2017 Jul 5.

Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

Science 2017 Jul;357(6348)

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA, and Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

Cell 2017 Jul;170(3):522-533.e15

Broad Institute of MIT and Harvard University, Cambridge, MA, USA; Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

Science 2017 03;355(6332)

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Nat Genet 2017 Feb 12;49(2):289-295. Epub 2016 Dec 12.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

Cell Stem Cell 2017 02 15;20(2):233-246.e7. Epub 2016 Dec 15.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

Proc Natl Acad Sci U S A 2017 02 30;114(7):E1291-E1300. Epub 2017 Jan 30.

Broad Institute, Cambridge, MA 02142;

Nature 2016 11 2;539(7628):309-313. Epub 2016 Nov 2.

Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.

J Clin Invest 2016 07 20;126(7):2757-72. Epub 2016 Jun 20.

Science 2016 May;352(6286):717-21

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

PLoS One 2015 22;10(5):e0116328. Epub 2015 May 22.

Department of Physics and School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America.

Nat Genet 2016 Mar 1;48(3):265-72. Epub 2016 Feb 1.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Mol Cell 2016 Jan 10;61(1):170-80. Epub 2015 Dec 10.

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

Nature 2016 Jan 23;529(7584):110-4. Epub 2015 Dec 23.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

Nat Biotechnol 2015 Nov 12;33(11):1165-72. Epub 2015 Oct 12.

Epigenomics Program, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

Cancer Discov 2015 Oct 30;5(10):1058-71. Epub 2015 Jul 30.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Broad Institute of Harvard University and MIT, Cambridge, Massachusetts.

Blood 2015 Oct 28;126(16):1930-9. Epub 2015 Aug 28.

Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA;

Nature 2015 Feb 29;518(7539):337-43. Epub 2014 Oct 29.

1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

Nature 2015 Feb 24;518(7539):355-359. Epub 2014 Dec 24.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

Proc Natl Acad Sci U S A 2014 Nov 4;111(46):E4946-53. Epub 2014 Nov 4.

Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, and

Cancer Cell 2014 Nov 30;26(5):668-681. Epub 2014 Oct 30.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Cancer Discov 2014 Oct 7;4(10):1154-67. Epub 2014 Aug 7.

Merck Research Laboratory, Boston, Massachusetts.

Nat Neurosci 2014 Sep 17;17(9):1156-63. Epub 2014 Aug 17.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

Nature 2014 Aug;512(7515):449-52

1] Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Informatics Program, Children's Hospital, Boston, Massachusetts 02215, USA.

Proc Natl Acad Sci U S A 2014 Aug;111(33):E3366

Genome Res 2014 Jun 21;24(6):920-9. Epub 2014 Apr 21.

Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA; US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA;

Science 2014 Jun 12;344(6190):1396-401. Epub 2014 Jun 12.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Broad Institute of Harvard and Massachusetts Institute of Techonology (MIT), Cambridge, MA 02142, USA. Howard Hughes Medical Institute Chevy Chase, MD 20815, USA.

Nat Genet 2014 Apr 2;46(4):364-70. Epub 2014 Mar 2.

1] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

Cell 2014 Apr 10;157(3):580-94. Epub 2014 Apr 10.

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

Proc Natl Acad Sci U S A 2014 Apr 21;111(17):6131-8. Epub 2014 Apr 21.

Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139.

Nat Biotechnol 2013 Dec 8;31(12):1133-6. Epub 2013 Sep 8.

1] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA. [2] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [3] Broad Institute of Harvard and MIT, Cambridge Massachusetts, USA. [4] Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

Nat Biotechnol 2013 Dec 9;31(12):1137-42. Epub 2013 Oct 9.

1] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts, USA. [4].

J Exp Med 2013 Nov 11;210(12):2641-59. Epub 2013 Nov 11.

Human Oncology and Pathogenesis Program, 2 Leukemia Service, 3 Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, and 4 Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.

Nucleic Acids Res 2013 Oct 14;41(19):e181. Epub 2013 Aug 14.

Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129, USA, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA, Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 01238, USA, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA and Howard Hughes Medical Institute, Chevy Chase, MD 02815, USA.

Dev Cell 2013 Sep;26(6):565-77

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan; CREST, Japan Science and Technology Agency, 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan; PREST, Japan Science and Technology Agency, 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan. Electronic address:

Nature 2013 Aug 7;500(7463):477-81. Epub 2013 Aug 7.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Cell 2013 May 9;153(5):1149-63. Epub 2013 May 9.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Cell Rep 2013 May 23;3(5):1567-79. Epub 2013 May 23.

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

Science 2013 Mar;339(6127):1567-70

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

PLoS Genet 2012 26;8(7):e1002774. Epub 2012 Jul 26.

Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan.

Cell 2013 Jan 17;152(3):642-54. Epub 2013 Jan 17.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Cancer Res 2012 Dec 27;72(24):6319-24. Epub 2012 Nov 27.

Research Department of Cancer Biology, University College London Cancer Institute, University College London, London, United Kingdom.

Cell 2012 Dec;151(6):1185-99

The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.

Genes Dev 2012 Dec;26(24):2802-16

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Genome Biol 2012 Oct 3;13(10):R85. Epub 2012 Oct 3.

Nature 2012 Sep;489(7414):155-9

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

Mol Cell 2012 Sep 30;47(5):810-22. Epub 2012 Aug 30.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Genome Res 2012 Sep;22(9):1813-31

Department of Genetics, Stanford University, Stanford, California 94305, USA.

PLoS One 2011 14;6(12):e28585. Epub 2011 Dec 14.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

Cancer Cell 2012 Aug;22(2):180-93

Human Oncology and Pathogenesis Program and Leukemia Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

Science 2012 Jun;336(6088):1513-4

Howard Hughes Medical Institute, Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Cell 2012 Jun;149(7):1474-87

Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA.

Cancer Cell 2012 Mar;21(3):329-31

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

Genome Biol 2012 Jan 27;13(1):139. Epub 2012 Jan 27.

Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

PLoS Genet 2011 Dec 8;7(12):e1002389. Epub 2011 Dec 8.

Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.

Cell 2011 Dec;147(7):1628-39

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Proc Natl Acad Sci U S A 2011 Sep 7;108(36):14908-13. Epub 2011 Jul 7.

Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

Proc Natl Acad Sci U S A 2011 Sep 11;108(36):14902-7. Epub 2011 Jul 11.

Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

Nat Protoc 2011 Sep 29;6(10):1656-68. Epub 2011 Sep 29.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

Nature 2011 May 23;473(7345):43-9. Epub 2011 Mar 23.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature 2011 Mar;471(7339):467-72

The Eli and Edythe L. Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02412, USA.

Cell 2011 Feb;144(4):513-25

Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, 10065, USA.

Mol Cell Biol 2011 Jan 8;31(2):351-64. Epub 2010 Nov 8.

RIKEN Research Center for Allergy and Immunology, 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan.

Nat Rev Genet 2011 Jan 30;12(1):7-18. Epub 2010 Nov 30.

Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

Cell Stem Cell 2011 Jan;8(1):96-105

Broad Institute, Cambridge, MA 02142, USA.

PLoS Genet 2010 Dec 9;6(12):e1001244. Epub 2010 Dec 9.

Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

Nat Biotechnol 2010 Oct 19;28(10):1097-105. Epub 2010 Sep 19.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.

Nat Biotechnol 2010 Oct;28(10):1045-8

Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.

Nat Methods 2010 Aug 11;7(8):615-8. Epub 2010 Jul 11.

Howard Hughes Medical Institute, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Cell Stem Cell 2010 Jun;6(6):591-602

Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

Genome Res 2010 Apr 4;20(4):519-25. Epub 2010 Feb 4.

Helicos BioSciences Corporation, Cambridge, MA 02139, USA.

Genes Dev 2010 Feb 1;24(4):368-80. Epub 2010 Feb 1.

Howard Hughes Medical Institute, New York University Medical School, New York, New York 10016, USA.