Bradley Bernstein

Bradley Bernstein

UNVERIFIED PROFILE

Are you Bradley Bernstein?   Register this Author

Register author
Bradley Bernstein

Bradley Bernstein

Publications by authors named "Bradley Bernstein"

Are you Bradley Bernstein?   Register this Author

100Publications

4443Reads

45Profile Views

Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis.

Oral Oncol 2019 Dec 6;99:104458. Epub 2019 Nov 6.

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; Department of Otolaryngology, Harvard Medical School, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2019.104458DOI Listing
December 2019

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.

Cancer Cell 2019 Nov 17;36(5):528-544.e10. Epub 2019 Oct 17.

Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2019.09.005DOI Listing
November 2019

Epigenome editing strategies for the functional annotation of CTCF insulators.

Nat Commun 2019 09 18;10(1):4258. Epub 2019 Sep 18.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-12166-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751197PMC
September 2019

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Cell 2019 Aug 18;178(4):835-849.e21. Epub 2019 Jul 18.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703186PMC
August 2019

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.

Cell 2019 03 28;176(6):1265-1281.e24. Epub 2019 Feb 28.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Ludwig Center at Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674193009
Publisher Site
http://dx.doi.org/10.1016/j.cell.2019.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515904PMC
March 2019

Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution.

Nat Genet 2019 01 17;51(1):19-25. Epub 2018 Dec 17.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0290-xDOI Listing
January 2019

GABPβ1L Wakes Up TERT.

Cancer Cell 2018 09;34(3):358-360

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.08.011DOI Listing
September 2018

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.

Cancer Cell 2018 01 14;33(1):29-43.e7. Epub 2017 Dec 14.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760343PMC
January 2018

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.

Cell 2017 Dec 30;171(7):1611-1624.e24. Epub 2017 Nov 30.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674173127
Publisher Site
http://dx.doi.org/10.1016/j.cell.2017.10.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878932PMC
December 2017

Cohesin Loss Eliminates All Loop Domains.

Cell 2017 Oct;171(2):305-320.e24

The Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Center for Theoretical Biological Physics, Rice University, Houston, TX 77030, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Departments of Computer Science and Computational and Applied Mathematics, Rice University, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.09.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846482PMC
October 2017

Epigenetic plasticity and the hallmarks of cancer.

Science 2017 Jul;357(6348)

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA, and Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aal2380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940341PMC
July 2017

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.

Cell 2017 Jul;170(3):522-533.e15

Broad Institute of MIT and Harvard University, Cambridge, MA, USA; Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.06.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785707PMC
July 2017

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.

Cell Stem Cell 2017 02 15;20(2):233-246.e7. Epub 2016 Dec 15.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291795PMC
February 2017

Single-molecule decoding of combinatorially modified nucleosomes.

Science 2016 May;352(6286):717-21

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad7701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904710PMC
May 2016

High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics.

PLoS One 2015 22;10(5):e0116328. Epub 2015 May 22.

Department of Physics and School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116328PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441486PMC
March 2016

Widespread RNA binding by chromatin-associated proteins.

Genome Biol 2016 Feb 16;17:28. Epub 2016 Feb 16.

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-016-0878-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756407PMC
February 2016

A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.

Mol Cell 2016 Jan 10;61(1):170-80. Epub 2015 Dec 10.

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707994PMC
January 2016

Insulator dysfunction and oncogene activation in IDH mutant gliomas.

Nature 2016 Jan 23;529(7584):110-4. Epub 2015 Dec 23.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature16490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831574PMC
January 2016

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.

Nat Biotechnol 2015 Nov 12;33(11):1165-72. Epub 2015 Oct 12.

Epigenomics Program, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.3383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636926PMC
November 2015

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.

Cancer Discov 2015 Oct 30;5(10):1058-71. Epub 2015 Jul 30.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Broad Institute of Harvard University and MIT, Cambridge, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-15-0370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592453PMC
October 2015

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

Blood 2015 Oct 28;126(16):1930-9. Epub 2015 Aug 28.

Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2015-06-649087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608240PMC
October 2015

Genetic and epigenetic fine mapping of causal autoimmune disease variants.

Nature 2015 Feb 29;518(7539):337-43. Epub 2014 Oct 29.

1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336207PMC
February 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530010PMC
February 2015

Comparative analysis of metazoan chromatin organization.

Nature 2014 Aug;512(7515):449-52

1] Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Informatics Program, Children's Hospital, Boston, Massachusetts 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227084PMC
August 2014

Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.

Genome Res 2014 Jun 21;24(6):920-9. Epub 2014 Apr 21.

Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA; US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.168930.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032856PMC
June 2014

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.

Science 2014 Jun 12;344(6190):1396-401. Epub 2014 Jun 12.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Broad Institute of Harvard and Massachusetts Institute of Techonology (MIT), Cambridge, MA 02142, USA. Howard Hughes Medical Institute Chevy Chase, MD 20815, USA.

View Article

Download full-text PDF

Source
http://www.sciencemag.org/cgi/doi/10.1126/science.1254257
Publisher Site
http://dx.doi.org/10.1126/science.1254257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123637PMC
June 2014

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Nat Genet 2014 Apr 2;46(4):364-70. Epub 2014 Mar 2.

1] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ng.2913
Publisher Site
http://dx.doi.org/10.1038/ng.2913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086945PMC
April 2014

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.

Cell 2014 Apr 10;157(3):580-94. Epub 2014 Apr 10.

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2014.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004670PMC
April 2014

Locus-specific editing of histone modifications at endogenous enhancers.

Nat Biotechnol 2013 Dec 8;31(12):1133-6. Epub 2013 Sep 8.

1] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA. [2] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [3] Broad Institute of Harvard and MIT, Cambridge Massachusetts, USA. [4] Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.2701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858395PMC
December 2013

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.

Nat Biotechnol 2013 Dec 9;31(12):1137-42. Epub 2013 Oct 9.

1] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts, USA. [4].

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nbt.2726
Publisher Site
http://dx.doi.org/10.1038/nbt.2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858462PMC
December 2013

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.

J Exp Med 2013 Nov 11;210(12):2641-59. Epub 2013 Nov 11.

Human Oncology and Pathogenesis Program, 2 Leukemia Service, 3 Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, and 4 Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20131141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832937PMC
November 2013

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.

Nucleic Acids Res 2013 Oct 14;41(19):e181. Epub 2013 Aug 14.

Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129, USA, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA, Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 01238, USA, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA and Howard Hughes Medical Institute, Chevy Chase, MD 02815, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkt716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799455PMC
October 2013

SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing.

Dev Cell 2013 Sep;26(6):565-77

Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan; CREST, Japan Science and Technology Agency, 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan; PREST, Japan Science and Technology Agency, 1-7-22 Suehiro, Tsurumi-ku, Yokohama 230-0045, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2013.08.016DOI Listing
September 2013

Epigenetic reprogramming in cancer.

Science 2013 Mar;339(6127):1567-70

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1230184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821556PMC
March 2013

A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.

Cancer Res 2012 Dec 27;72(24):6319-24. Epub 2012 Nov 27.

Research Department of Cancer Biology, University College London Cancer Institute, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-12-3658DOI Listing
December 2012

Molecular biology. Genetic events that shape the cancer epigenome.

Science 2012 Jun;336(6088):1513-4

Howard Hughes Medical Institute, Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1223730DOI Listing
June 2012

A tell-tail sign of chromatin: histone mutations drive pediatric glioblastoma.

Cancer Cell 2012 Mar;21(3):329-31

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2012.03.001DOI Listing
March 2012

DNA-protein interactions in high definition.

Genome Biol 2012 Jan 27;13(1):139. Epub 2012 Jan 27.

Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2012-13-1-139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334573PMC
January 2012

Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq.

Nat Protoc 2011 Sep 29;6(10):1656-68. Epub 2011 Sep 29.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2011.402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493313PMC
September 2011

Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains.

Cell 2011 Feb;144(4):513-25

Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, 10065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2011.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572774PMC
February 2011

Charting histone modifications and the functional organization of mammalian genomes.

Nat Rev Genet 2011 Jan 30;12(1):7-18. Epub 2010 Nov 30.

Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
https://www.cs.duke.edu/courses/cps262/spring13/pdf/zhou.201
Web Search
http://dx.doi.org/10.1038/nrg2905DOI Listing
January 2011

GC-rich sequence elements recruit PRC2 in mammalian ES cells.

PLoS Genet 2010 Dec 9;6(12):e1001244. Epub 2010 Dec 9.

Howard Hughes Medical Institute and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
https://dash.harvard.edu/bitstream/handle/1/4874826/3000368.
Web Search
http://dx.plos.org/10.1371/journal.pgen.1001244
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1001244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000368PMC
December 2010