Bradley A Maron

Bradley A Maron

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Bradley A Maron

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Pulmonary arterial hypertension in the modern era: The intersection of genotype and phenotype.

J Heart Lung Transplant 2020 Feb 9;39(2):113-114. Epub 2019 Nov 9.

Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Department of Cardiology, Boston VA Healthcare System, West Roxbury, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2019.10.003DOI Listing
February 2020

Metabolic syndrome, neurohumoral modulation and pulmonary arterial hypertension.

Br J Pharmacol 2019 Dec 27. Epub 2019 Dec 27.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1111/bph.14968DOI Listing
December 2019

Circulating NEDD9 is increased in pulmonary arterial hypertension: A multicenter, retrospective analysis.

J Heart Lung Transplant 2019 Dec 31. Epub 2019 Dec 31.

Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2019.12.002DOI Listing
December 2019

Mildly increased pulmonary arterial pressure: a new disease entity or just a marker of poor prognosis?

Eur J Heart Fail 2019 Sep 13;21(9):1057-1061. Epub 2019 Aug 13.

Medical University of Graz, Graz, Austria.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ejhf.1570
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http://dx.doi.org/10.1002/ejhf.1570DOI Listing
September 2019

Association of Mild Echocardiographic Pulmonary Hypertension With Mortality and Right Ventricular Function.

JAMA Cardiol 2019 Sep 18. Epub 2019 Sep 18.

Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1001/jamacardio.2019.3345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751783PMC
September 2019

Pulmonary Hypertension in Patients with Heart Failure with Preserved Ejection Fraction. Where to Draw the Line.

Am J Respir Crit Care Med 2019 Aug;200(3):278-279

4Department of MedicineBrigham and Women's Hospital and Harvard Medical SchoolBoston, Massachusettsand.

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http://dx.doi.org/10.1164/rccm.201903-0689EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680312PMC
August 2019

Toward Early Diagnosis of Pulmonary Hypertension: Lessons From Oz.

J Am Coll Cardiol 2019 Jun;73(21):2673-2675

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2019.03.473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747056PMC
June 2019

Correspondence on the debate regarding the haemodynamic definition of pulmonary hypertension.

Eur Respir J 2019 Jun 5;53(6). Epub 2019 Jun 5.

Dept of Cardiology, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1183/13993003.00727-2019DOI Listing
June 2019

Back to the Future: Building Up the Case for Exploring Red Blood Cell Morphology in Pulmonary Arterial Hypertension.

Authors:
Bradley A Maron

Ann Am Thorac Soc 2019 May;16(5):548-550

Division of Cardiovascular Medicine, Brigham and Women's Hospital Boston, MA and Department of Cardiology, Boston VA Healthcare System, West Roxbury, Massachusetts.

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http://dx.doi.org/10.1513/AnnalsATS.201901-043EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491058PMC
May 2019

A Concerning Trend for Patients With Pulmonary Hypertension in the Era of Evidence-Based Medicine.

Circulation 2019 04;139(16):1861-1864

Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City (J.J.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.037613DOI Listing
April 2019

Precision Medicine in Pulmonary Arterial Hypertension.

Circ Res 2019 03;124(6):832-833

From the Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.314757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419751PMC
March 2019

TORward a Molecular Convergence Point in Pulmonary Arterial Hypertension With mTOR.

JACC Basic Transl Sci 2018 Dec 31;3(6):763-765. Epub 2018 Dec 31.

Department of Medicine, Imperial College of London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacbts.2018.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315047PMC
December 2018

Systems Biology Approaches to Redox Metabolism in Stress and Disease States.

Antioxid Redox Signal 2018 10 20;29(10):953-972. Epub 2017 Dec 20.

1 Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts.

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http://dx.doi.org/10.1089/ars.2017.7256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104248PMC
October 2018

Mild Pulmonary Hypertension Is Associated With Increased Mortality: A Systematic Review and Meta-Analysis.

J Am Heart Assoc 2018 09;7(18):e009729

1 Providence Veterans Affairs Medical Center Warren Alpert Medical School of Brown University Providence RI.

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http://dx.doi.org/10.1161/JAHA.118.009729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222957PMC
September 2018

Update in Pulmonary Vascular Disease 2016 and 2017.

Am J Respir Crit Care Med 2018 07;198(1):13-23

5 Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201801-0062UPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034126PMC
July 2018

Pulmonary Vascular Disease Across the Life Span: A Call for Bridging Pediatric and Adult Cardiopulmonary Research and Care.

Am J Respir Crit Care Med 2018 Jul 18. Epub 2018 Jul 18.

Brigham and Women's Hospital Biomedical Research Institute, 278479, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1164/rccm.201807-1240EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298635PMC
July 2018

Segmental Arterial Mediolysis: An Important but Often Overlooked Cause of Multi-Vessel Thrombosis.

Am J Med 2018 06 2;131(6):e231-e234. Epub 2018 Mar 2.

Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Department of Cardiology, Boston VA Healthcare System, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2018.01.057DOI Listing
June 2018

Pulmonary Hypertension: Good Intentions, But a Questionable Approach.

Ann Am Thorac Soc 2018 06;15(6):664-666

6 Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana; and.

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http://dx.doi.org/10.1513/AnnalsATS.201803-197EDDOI Listing
June 2018

Redefining pulmonary hypertension.

Lancet Respir Med 2018 03 18;6(3):168-170. Epub 2017 Dec 18.

Department of Medicine, University of Pittsburgh Medical Center and Pittsburgh Heart, Lung, Blood, and Vascular Medical Institute, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/S2213-2600(17)30498-8DOI Listing
March 2018

Network Analysis to Risk Stratify Patients With Exercise Intolerance.

Circ Res 2018 03 5;122(6):864-876. Epub 2018 Feb 5.

From the Department of Medicine (W.M.O., R.K.F.O., R.-S.W., D.M.R., B.M.W., C.A.M., J.L., A.B.W., D.M.S., J.A.L.), Division of Pulmonary and Critical Care Medicine (W.M.O., B.M.W., A.B.W., D.M.S.), Division of Cardiovascular Medicine (A.R.O., C.A.M., J.L., J.A.L., B.A.M.), and Department of Radiology (J.H.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Division of Respiratory Diseases, Department of Medicine, Federal University of São Paulo (UNIFESP), Brazil (R.K.F.O.); Department of Cardiology, Boston Children's Hospital and Harvard Medical School, MA (A.R.O.); Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston (G.A.A.); Division of Cardiology, Department of Medicine, Providence Veterans Affairs Medical Center and Alpert Medical School of Brown University, Providence, RI (G.C.); Department of Pulmonology, Medical University of Graz, Austria (A.T., H.O., G.K.); Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria (A.T., H.O., G.K.); and Department of Cardiology, Boston VA Healthcare System, MA (B.A.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924425PMC
March 2018

Under Pressure to Clarify Pulmonary Hypertension Clinical Risk.

Am J Respir Crit Care Med 2018 02;197(4):423-426

4 University of Pittsburgh Medical Center and.

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http://dx.doi.org/10.1164/rccm.201711-2306EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821912PMC
February 2018

PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics.

Circ Res 2017 10;121(10):1136-1139

From the Vanderbilt University, Nashville, TN (A.R.H., J.H.N.); Cleveland Clinic, OH (G.J.B., M.A.A., J.B., S.A.A.C., S.C.E., B.H., J.K.L., M.A.O., W.H.W.T.); Wayne State University/John D. Dingell VAMC, Detroil, MI (A.A.); Columbia University, New York, NY (E.B.R., W.K.C.); Mayo Clinic, Rochester, MN (B.A.B., R.P.F.); Pulmonary Hypertension Association, Silver Spring, MD (M.P.G.); New York University Medical Center (G.G.); Johns Hopkins Hospital, Baltimore, MD (P.M.H., S.C.M.); Tufts Medical Center, Boston, MA (N.S.H.); Weill Cornell Medicine, New York, NY (E.M.H.); Brigham and Women's Hospital, Boston, MA (B.A.M., D.M.S., A.B.W., J.A.L.); The University of Arizona, Tucson (F.P.R., J.X.-J.Y.); and National Heart, Lung and Blood Institute, Bethesda, MD (L.X.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685561PMC
October 2017

What's in a side effect? The association between pulmonary vasodilator adverse drug events and clinical outcomes in patients with pulmonary arterial hypertension.

Int J Cardiol 2017 Aug 6;240:386-391. Epub 2017 Apr 6.

Stanford University Medical Center, Division of PCCM, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.04.016DOI Listing
August 2017

Functional impact of exercise pulmonary hypertension in patients with borderline resting pulmonary arterial pressure.

Pulm Circ 2017 Jul-Sep;7(3):654-665. Epub 2017 Jun 8.

1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/2045893217709025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841910PMC
June 2017

Revisiting Athlete's Heart Versus Pathologic Hypertrophy: ARVC and the Right Ventricle.

JACC Cardiovasc Imaging 2017 04 17;10(4):394-397. Epub 2016 Aug 17.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Cardiology, Boston VA Healthcare System, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcmg.2016.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303558PMC
April 2017

Mechanism of Progressive Heart Failure and Significance of Pulmonary Hypertension in Obstructive Hypertrophic Cardiomyopathy.

Circ Heart Fail 2017 Apr;10(4):e003689

From the Division of Cardiology, Hypertrophic Cardiomyopathy Institute (M.C., E.J.R., B.J.M., M.S.M.) and Division of Pulmonary, Critical Care and Sleep Medicine (N.S.H., I.R.P.), Tufts Medical Center, Boston, MA; Division of Internal Medicine, Department of Medical Sciences, University of Torino, Italy (M.C., A.M.); Department of Pediatric Cardiology, Boston Children's Hospital, MA (A.R.O.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (B.A.M.); and Department of Cardiology, Boston VA Healthcare System, MA (B.A.M.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390526PMC
April 2017

Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome: Clinical Determinants and Association With Outcome From the Fluid and Catheter Treatment Trial Cohort.

Crit Care Med 2017 03;45(3):422-429

1Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD. 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD. 3Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA. 4Department of Cardiology, Boston VA Healthcare System, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0000000000002186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315617PMC
March 2017

Death or Severe Injury at the Ball Game.

Curr Sports Med Rep 2016 May-Jun;15(3):132-3

1Department of Emergency Medicine, Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, RI; 2Villanova University, Villanova, PA; and 3Division of Cardiovascular Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1249/JSR.0000000000000256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868395PMC
February 2017

Diagnosis, Treatment, and Clinical Management of Pulmonary Arterial Hypertension in the Contemporary Era: A Review.

JAMA Cardiol 2016 Dec;1(9):1056-1065

Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna, Italy.

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http://jamanetwork.com/data/Journals/CARDIOLOGY/935934/HRV16
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http://dx.doi.org/10.1001/jamacardio.2016.4471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177491PMC
December 2016

Pulmonary vascular and ventricular dysfunction in the susceptible patient (2015 Grover Conference series).

Pulm Circ 2016 Dec;6(4):426-438

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1086/688315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210067PMC
December 2016

Treatment differences in pulmonary arterial hypertension management.

Pulm Circ 2016 Dec;6(4):619

University Hospital, University of Utah, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1086/688909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210068PMC
December 2016

Systems biology: An emerging strategy for discovering novel pathogenetic mechanisms that promote cardiovascular disease.

Glob Cardiol Sci Pract 2016 Sep 30;2016(3):e201627. Epub 2016 Sep 30.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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https://globalcardiologyscienceandpractice.com/index.php/gcs
Publisher Site
http://dx.doi.org/10.21542/gcsp.2016.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642838PMC
September 2016

Genetic Misdiagnoses and the Potential for Health Disparities.

N Engl J Med 2016 Aug;375(7):655-65

From the Departments of Biomedical Informatics (A.K.M., D.M.M., I.S.K.), Pathology (B.H.F.), and Medicine (B.A.M., J.L.), Harvard Medical School, the Departments of Pathology, Massachusetts General Hospital (B.H.F.), and the Department of Pathology (H.L.R.), Division of Cardiovascular Medicine (B.A.M.), and Department of Medicine (B.A.M., J.L.), Brigham and Women's Hospital, Boston, and the Division of Health Sciences and Technology, Harvard-Massachusetts Institute of Technology (MIT) (A.K.M., I.S.K.), the Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine (B.H.F., H.L.R.), and the Computer Science and Artificial Intelligence Laboratory, MIT (P.S.), Cambridge - all in Massachusetts; and the Laboratory of Molecular Cardiology, Department of Cardiology, the Heart Center, University Hospital of Copenhagen, Rigshospitalet, and the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen (M.S.O.) - both in Copenhagen.

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http://dx.doi.org/10.1056/NEJMsa1507092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292722PMC
August 2016

Relation of Doppler Tissue Imaging Parameters With Heart Failure Progression in Hypertrophic Cardiomyopathy.

Am J Cardiol 2016 06 19;117(11):1808-14. Epub 2016 Mar 19.

The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2016.03.018DOI Listing
June 2016

Independence Day: Separating Right Ventricular Function From Pulmonary Arterial Hypertension in Systemic Sclerosis.

Authors:
Bradley A Maron

Circulation 2016 Jun 11;133(24):2345-7. Epub 2016 May 11.

From Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, and Department of Cardiology, Boston VA Healthcare System, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928682PMC
June 2016

Update in Pulmonary Vascular Disease 2015.

Am J Respir Crit Care Med 2016 06;193(12):1337-44

4 Division of Cardiology, Department of Medicine, University of Pittsburgh Medical Center and Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201601-0143UPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910895PMC
June 2016

Molecular Mechanisms of Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.

Int J Mol Sci 2016 May 18;17(5). Epub 2016 May 18.

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/ijms17050761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881582PMC
May 2016

Systems medicine: evolution of systems biology from bench to bedside.

Wiley Interdiscip Rev Syst Biol Med 2015 Jul-Aug;7(4):141-61. Epub 2015 Apr 17.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/wsbm.1297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457580PMC
March 2016

The quest for biomarker discovery in pulmonary arterial hypertension: the right takes lessons from the left.

Authors:
Bradley A Maron

Heart 2016 Mar;102(5):335-6

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA Department of Cardiology, Boston VA Healthcare System, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/heartjnl-2015-309070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758692PMC
March 2016

Association of Borderline Pulmonary Hypertension With Mortality and Hospitalization in a Large Patient Cohort: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program.

Circulation 2016 Mar 12;133(13):1240-8. Epub 2016 Feb 12.

From Veterans Affairs Boston Healthcare System, MA (B.A.M., R.H.G.); Brigham and Women's Hospital and Harvard Medical School, Boston, MA (B.A.M., A.R.O., T.S., J.A.L.); Veterans Affairs Eastern Colorado Health Care System, Denver (E.H., T.M.M., M.A.S., M.E.P., G.K.G., A.E.B., J.R.); University of Colorado School of Medicine (T.M.M.); Boston Children's Hospital, MA (A.R.O.); Department of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (R.J.T.); Indiana University School of Medicine and Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis (T.L.); Office of the Assistant Secretary for Planning and Evaluation, United States Department of Health and Human Services, Washington, DC (K.E.J.); Veterans Affairs Pittsburgh Healthcare System, PA (D.J.K.); VA Puget Sound Health Care System and University of Washington, Seattle (E.R.S.); Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, CA (R.T.Z.); Cincinnati Veterans Affairs Medical Center and University of Cincinnati, OH (J.M.E.); and Providence Veterans Affairs Medical Center and Alpert Medical School of Brown University, Providence, RI (G.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811678PMC
March 2016

Echocardiographic predictors of mortality in patients with pulmonary hypertension and cardiopulmonary comorbidities.

PLoS One 2015 16;10(3):e0119277. Epub 2015 Mar 16.

Vascular Research Laboratory, Providence VA Medical Center, Providence, Rhode Island, United States of America; Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119277PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361665PMC
January 2016

Protocol for exercise hemodynamic assessment: performing an invasive cardiopulmonary exercise test in clinical practice.

Pulm Circ 2015 Dec;5(4):610-8

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA ; Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston Massachusetts, USA.

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http://dx.doi.org/10.1086/683815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671735PMC
December 2015

Emerging Concepts in the Molecular Basis of Pulmonary Arterial Hypertension: Part II: Neurohormonal Signaling Contributes to the Pulmonary Vascular and Right Ventricular Pathophenotype of Pulmonary Arterial Hypertension.

Circulation 2015 Jun;131(23):2079-91

From Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (B.A.M., J.A.L.); and Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston, MA (B.A.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.006980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465126PMC
June 2015

Hemodynamics should be the primary approach to diagnosing, following, and managing pulmonary arterial hypertension.

Authors:
Bradley A Maron

Can J Cardiol 2015 Apr 28;31(4):515-20. Epub 2014 Sep 28.

Brigham and Women's Hospital and Harvard Medical School, Department of Medicine, Division of Cardiovascular Medicine, 75 Francis St, Boston, and the Department of Cardiology, Veterans Affairs Boston Healthcare System, West Roxbury, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2014.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377110PMC
April 2015

Building the case for novel clinical trials in pulmonary arterial hypertension.

Circ Cardiovasc Qual Outcomes 2015 Jan;8(1):114-23

From the Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City (J.J.R.); Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.D.R.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (B.A.M.); and Department of Cardiology, Boston VA Heathcare System, Boston, MA (B.A.M.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.114.001319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304412PMC
January 2015

Explaining unexplained dyspnea: the ever "holesome" heart.

Circulation 2014 Dec;130(23):2057-66

From the Massachusetts General Hospital and Harvard Medical School, Division of Cardiology, Boston (D.M.D.); Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston, MA (D.L.B., J.R.A., B.A.M.); and Brigham and Women's Hospital and Harvard Medical School, Division of Cardiovascular Medicine, Boston, MA (D.L.B., J.R.A., B.A.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.010810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255914PMC
December 2014

Emerging hemodynamic signatures of the right heart (Third International Right Heart Failure Summit, part 2).

Authors:
Bradley A Maron

Pulm Circ 2014 Dec;4(4):705-16

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; and Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1086/678544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278630PMC
December 2014

The heterogeneity of clinical practice patterns among an international cohort of pulmonary arterial hypertension experts.

Pulm Circ 2014 Sep;4(3):441-51

Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; and Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1086/677357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278603PMC
September 2014

Pulmonary hypertension: pathophysiology and signaling pathways.

Handb Exp Pharmacol 2013 ;218:31-58

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, NRB Room 0630-AO, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/978-3-642-38664-0_2DOI Listing
July 2014

Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis.

Circulation 2014 Jul 28;130(2):168-79. Epub 2014 Apr 28.

From the Divisions of Cardiovascular Medicine (B.A.M., S.Y.C., E.A., Y.-Y.Z., J.L., J.A.L.) and Pulmonary and Critical Care Medicine (W.M.O.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston, MA (B.A.M.); and Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA (S.O.V.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.007690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090713PMC
July 2014

The role of the renin-angiotensin-aldosterone system in the pathobiology of pulmonary arterial hypertension (2013 Grover Conference series).

Pulm Circ 2014 Jun;4(2):200-10

Brigham and Women's Hospital, Division of Cardiovascular Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1086/675984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070776PMC
June 2014

Contemporary approach to paradoxical embolism.

Circulation 2014 May;129(18):1892-7

From Brigham and Women's Hospital and Harvard Medical School, Department of Medicine, Division of Cardiovascular Medicine, Boston, MA (M.N., B.A.M.); Dyspnea Center at Brigham and Women's Hospital and Harvard Medical School, Boston, MA (B.A.M.); and Department of Cardiology, Veterans Affairs Boston Healthcare System, Boston, MA (B.A.M.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053687PMC
May 2014

Towards widespread noninvasive assessment of pulmonary vascular resistance in clinical practice.

J Am Soc Echocardiogr 2014 Jan 23;27(1):108-9. Epub 2013 Nov 23.

Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.

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https://linkinghub.elsevier.com/retrieve/pii/S08947317130083
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http://dx.doi.org/10.1016/j.echo.2013.10.010DOI Listing
January 2014

SDF-1α in glycan nanoparticles exhibits full activity and reduces pulmonary hypertension in rats.

Biomacromolecules 2013 Nov 18;14(11):4009-20. Epub 2013 Oct 18.

Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/bm401122qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833441PMC
November 2013

A simple echocardiographic method to estimate pulmonary vascular resistance.

Am J Cardiol 2013 Sep 1;112(6):873-82. Epub 2013 Jun 1.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.amjcard.2013.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317360PMC
September 2013

Subcellular localization of oxidants and redox modulation of endothelial nitric oxide synthase.

Circ J 2012 18;76(11):2497-512. Epub 2012 Oct 18.

Department of Medicine, Cardiovascular Medicine Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1253/circj.cj-12-1207DOI Listing
March 2013

Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study.

Eur J Heart Fail 2013 Mar 30;15(3):277-83. Epub 2012 Oct 30.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://doi.wiley.com/10.1093/eurjhf/hfs173
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http://dx.doi.org/10.1093/eurjhf/hfs173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576899PMC
March 2013

The invasive cardiopulmonary exercise test.

Circulation 2013 Mar;127(10):1157-64

Department of Internal Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.112.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.104463DOI Listing
March 2013

S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system.

Antioxid Redox Signal 2013 Jan 5;18(3):270-87. Epub 2012 Sep 5.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1089/ars.2012.4744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518544PMC
January 2013

Protocol for vasoreactivity testing with epoprostenol in pulmonary hypertension.

Crit Pathw Cardiol 2012 Mar;11(1):40-2

Department of Cardiology, Veterans Affairs Boston Healthcare System, West Roxbury, MA, USA.

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https://insights.ovid.com/crossref?an=00132577-201203000-000
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http://dx.doi.org/10.1097/HPC.0b013e3182480725DOI Listing
March 2012

Paradoxical embolism.

Circulation 2010 Nov;122(19):1968-72

Division of Cardiovascular Medicine, Brigham and Women's Hospital, PBB-1, 75 Francis St, Boston, MA 02115, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.110.961920DOI Listing
November 2010

Aldosterone receptor antagonists: effective but often forgotten.

Circulation 2010 Feb;121(7):934-9

Brigham and Women's Hospital, Division of Cardiovascular Medicine, PBB-1, 75 Francis St, Boston, MA 02115, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.109.8
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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.895235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828634PMC
February 2010

Catheter-directed thrombolysis for giant right atrial thrombus.

Circ Cardiovasc Imaging 2010 Jan;3(1):126-7

Department of Internal Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.109.906487DOI Listing
January 2010

The treatment of hyperhomocysteinemia.

Annu Rev Med 2009 ;60:39-54

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.med.60.0418
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http://dx.doi.org/10.1146/annurev.med.60.041807.123308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716415PMC
September 2009

Echocardiographic capture of right ventricular wall rupture during inferior wall acute myocardial infarction.

Am J Cardiol 2009 May 1;103(10):1478-80. Epub 2009 Apr 1.

Department of Internal Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.amjcard.2009.01.357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563804PMC
May 2009

Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells.

J Biol Chem 2009 Mar 13;284(12):7665-72. Epub 2009 Jan 13.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M809460200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658060PMC
March 2009

Mineralocorticoid receptor antagonists and endothelial function.

Curr Opin Investig Drugs 2008 Sep;9(9):963-9

Harvard Medical School, Brigham and Women's Hospital, Department of Medicine, Cardiovascular Division, 77 Avenue Louis Pasteur, NRB 0630K, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967484PMC
September 2008

Personality as a prognostic factor for specialty choice: a prospective study of 4 medical school classes.

Medscape J Med 2008 Feb 27;10(2):49. Epub 2008 Feb 27.

Department of Internal Medicine, Boonshoft School of Medicine at Wright State University, Dayton, Ohio, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270893PMC
February 2008

Should hyperhomocysteinemia be treated in patients with atherosclerotic disease?

Curr Atheroscler Rep 2007 Nov;9(5):375-83

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s11883-007-0048-xDOI Listing
November 2007